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The map label for this gene is atoS [H]

Identifier: 157961579

GI number: 157961579

Start: 2133239

End: 2134972

Strand: Direct

Name: atoS [H]

Synonym: Spea_1755

Alternate gene names: 157961579

Gene position: 2133239-2134972 (Clockwise)

Preceding gene: 157961577

Following gene: 157961580

Centisome position: 41.23

GC content: 46.42

Gene sequence:

>1734_bases
ATGTCGATAAAACGCTACGTGTTTATGCTATTTGGTGCGTTAATCCTATTGCTGGCGATGAGCCAGCTATTTGTGGCGCA
GTATTTTAAGACTCAACTACAGGCAGAGCTTGAGCAAAGCTCAAAAAGTTTATCAAAGAGCTTAGTCAGCGTGGTAATTG
AGAACGCTGCAGAGCTTGAACGCATGGAGTTTTCATTTCCACAGACGCCAGCTAGGGTCGCTGAGCTCATGCCCAAAGCT
GAGGTGGATAGCATCGATTGGGTTGAGAGCAGTGAGCTGATAAACGAAAGGTTTGAGCATGAGGTTGAACGGTTGACTGA
CGAGGCTGAGCAGGAGATTGATATCCAGCTAGATAGCTTAAATAGTGAAATCGATCAGCTCGCGTTTGAGCTTGCTAAAG
GTGTGTCCGAGGGAGGGAAGTCACAACTTAAAAGCGATGCATTTAAGACAAAGCAGAAAGCATTGAAAGAGAAAGTGCAA
GCCTTGTTAGAAAAAGAACGGGTGCTATTGGAAAGCAATCGCGAGAATATGCAGCAACTGCGCAAGCAAGCGGCGCGAGA
ATATCAGCAACGAGTAGAGCGGAGTCTAGAGAGTATTGAGATCCATACCGATGAGTGGCTTAAAGAGGGGCGAGTCCTCA
TTGTTGAGGGGCAGCACAGTAATGGCGGATCCATTGAGCAGAATGAAGAGCGCAGTGTTGACTTACCCAGTGGTGGTACA
AATCATCTTTTAGAACGCTTTAGCGAATCGGTTTTGCTAGCCATTCTTATCACGAGTGTGATGGCTCTACTACTGGCCTA
CTGGCTTAGCCACCATGTGACAGGGCCCTTGAGTGAGCTGGCTGGTGGTCATCAAAAATTGGCAAAGGGCGAATTTGGTG
TGCAACTTAAAGAGCAAGGGGTTAAAGAGTTAAAGCAGATCTTAACGGGTTTTAATCGCATGAGTCTGGCATTAGCGAAC
TTGAGTAAGAAAGAGCAACAGATGTCGCAGCAGCAACACTTGGCCGATCTTGGTCAAATTACCCGGGGTATTGCCCACAG
CTTGAGAAACCCGTTACATACTTTGGGATTACTCTCAGAGCAGAGCACTTGCAGTGAAACCTTGGCCGAGCGCGAGAAAC
TTAATAATAAGATGCAGCAGAAAATTGCCTTGATGGATAAAAGCATTCAGTCGCTGTTGACGCTTTCGAGCCATGAGGTG
GCACGTGACAAAGCCATCCCGTTAAACGCCATCATTCAAGATGTACTTTTGGAGTTATCGATCACCGGGATTAAACCGAA
AGTCATGTTTGACCCACAAAGCATTAAGCTTTTCGTCAATGGAGCAGAGTCTGAGCTTAGAAGTATCTTACATGCGGTGA
TGATTAACGCGGTAGAAGCCGATCCGGATGCTAAGCAGATAAAAATCGAGTTGACTCAAGATGTGAATGCCAAGAAAGTC
ATCATTACCGATTGGGGCAAAGGGATTGATCCTTTGGTTAAGACGCAGATGTTTAAGCCTCATGTTACCACTAAAACAGA
AGGCTCGGGCATGGGGATCTATATCGCGAAGCGCTTAATCGAGAGCCACTATGATGGCGAAATCCAGTTTGATGACAACC
CCCAAGGAGGCACCATCGTGACGCTTATCTTTTGTCGTGGTGAACCAGGGCCTGACTCAAGCGCCAAATCAAACATAGAC
TCAAACTCTGACTCAAACAGAAAGCCTTCGTATCAAGGTAAGGTGAAACCATGA

Upstream 100 bases:

>100_bases
GGCCTAGAGTTTTGGTATCAATCTTGTATAAACAAACGGGTTAAGAGTCTTGTACATATAAGATATGCTCGAATTGAAAT
AGGGAAATAAAATAAGAATT

Downstream 100 bases:

>100_bases
ATAAAGCGCCGTTACAGATCTTAGTGGTGGAAGACGAGCCCGATCAACGAGAGTTAATTTGTCAAATACTTGCCTCGAAT
CAATATCAGATCACCAGCGC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 577; Mature: 576

Protein sequence:

>577_residues
MSIKRYVFMLFGALILLLAMSQLFVAQYFKTQLQAELEQSSKSLSKSLVSVVIENAAELERMEFSFPQTPARVAELMPKA
EVDSIDWVESSELINERFEHEVERLTDEAEQEIDIQLDSLNSEIDQLAFELAKGVSEGGKSQLKSDAFKTKQKALKEKVQ
ALLEKERVLLESNRENMQQLRKQAAREYQQRVERSLESIEIHTDEWLKEGRVLIVEGQHSNGGSIEQNEERSVDLPSGGT
NHLLERFSESVLLAILITSVMALLLAYWLSHHVTGPLSELAGGHQKLAKGEFGVQLKEQGVKELKQILTGFNRMSLALAN
LSKKEQQMSQQQHLADLGQITRGIAHSLRNPLHTLGLLSEQSTCSETLAEREKLNNKMQQKIALMDKSIQSLLTLSSHEV
ARDKAIPLNAIIQDVLLELSITGIKPKVMFDPQSIKLFVNGAESELRSILHAVMINAVEADPDAKQIKIELTQDVNAKKV
IITDWGKGIDPLVKTQMFKPHVTTKTEGSGMGIYIAKRLIESHYDGEIQFDDNPQGGTIVTLIFCRGEPGPDSSAKSNID
SNSDSNRKPSYQGKVKP

Sequences:

>Translated_577_residues
MSIKRYVFMLFGALILLLAMSQLFVAQYFKTQLQAELEQSSKSLSKSLVSVVIENAAELERMEFSFPQTPARVAELMPKA
EVDSIDWVESSELINERFEHEVERLTDEAEQEIDIQLDSLNSEIDQLAFELAKGVSEGGKSQLKSDAFKTKQKALKEKVQ
ALLEKERVLLESNRENMQQLRKQAAREYQQRVERSLESIEIHTDEWLKEGRVLIVEGQHSNGGSIEQNEERSVDLPSGGT
NHLLERFSESVLLAILITSVMALLLAYWLSHHVTGPLSELAGGHQKLAKGEFGVQLKEQGVKELKQILTGFNRMSLALAN
LSKKEQQMSQQQHLADLGQITRGIAHSLRNPLHTLGLLSEQSTCSETLAEREKLNNKMQQKIALMDKSIQSLLTLSSHEV
ARDKAIPLNAIIQDVLLELSITGIKPKVMFDPQSIKLFVNGAESELRSILHAVMINAVEADPDAKQIKIELTQDVNAKKV
IITDWGKGIDPLVKTQMFKPHVTTKTEGSGMGIYIAKRLIESHYDGEIQFDDNPQGGTIVTLIFCRGEPGPDSSAKSNID
SNSDSNRKPSYQGKVKP
>Mature_576_residues
SIKRYVFMLFGALILLLAMSQLFVAQYFKTQLQAELEQSSKSLSKSLVSVVIENAAELERMEFSFPQTPARVAELMPKAE
VDSIDWVESSELINERFEHEVERLTDEAEQEIDIQLDSLNSEIDQLAFELAKGVSEGGKSQLKSDAFKTKQKALKEKVQA
LLEKERVLLESNRENMQQLRKQAAREYQQRVERSLESIEIHTDEWLKEGRVLIVEGQHSNGGSIEQNEERSVDLPSGGTN
HLLERFSESVLLAILITSVMALLLAYWLSHHVTGPLSELAGGHQKLAKGEFGVQLKEQGVKELKQILTGFNRMSLALANL
SKKEQQMSQQQHLADLGQITRGIAHSLRNPLHTLGLLSEQSTCSETLAEREKLNNKMQQKIALMDKSIQSLLTLSSHEVA
RDKAIPLNAIIQDVLLELSITGIKPKVMFDPQSIKLFVNGAESELRSILHAVMINAVEADPDAKQIKIELTQDVNAKKVI
ITDWGKGIDPLVKTQMFKPHVTTKTEGSGMGIYIAKRLIESHYDGEIQFDDNPQGGTIVTLIFCRGEPGPDSSAKSNIDS
NSDSNRKPSYQGKVKP

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=229, Percent_Identity=30.1310043668122, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=24.5689655172414, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64457; Mature: 64325

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKRYVFMLFGALILLLAMSQLFVAQYFKTQLQAELEQSSKSLSKSLVSVVIENAAELE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMEFSFPQTPARVAELMPKAEVDSIDWVESSELINERFEHEVERLTDEAEQEIDIQLDSL
HHHCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSEIDQLAFELAKGVSEGGKSQLKSDAFKTKQKALKEKVQALLEKERVLLESNRENMQQL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RKQAAREYQQRVERSLESIEIHTDEWLKEGRVLIVEGQHSNGGSIEQNEERSVDLPSGGT
HHHHHHHHHHHHHHHHHHEECCHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCH
NHLLERFSESVLLAILITSVMALLLAYWLSHHVTGPLSELAGGHQKLAKGEFGVQLKEQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHCCCCCCHHHHHH
VKELKQILTGFNRMSLALANLSKKEQQMSQQQHLADLGQITRGIAHSLRNPLHTLGLLSE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QSTCSETLAEREKLNNKMQQKIALMDKSIQSLLTLSSHEVARDKAIPLNAIIQDVLLELS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ITGIKPKVMFDPQSIKLFVNGAESELRSILHAVMINAVEADPDAKQIKIELTQDVNAKKV
HCCCCCEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEE
IITDWGKGIDPLVKTQMFKPHVTTKTEGSGMGIYIAKRLIESHYDGEIQFDDNPQGGTIV
EEECCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEE
TLIFCRGEPGPDSSAKSNIDSNSDSNRKPSYQGKVKP
EEEEECCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SIKRYVFMLFGALILLLAMSQLFVAQYFKTQLQAELEQSSKSLSKSLVSVVIENAAELE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMEFSFPQTPARVAELMPKAEVDSIDWVESSELINERFEHEVERLTDEAEQEIDIQLDSL
HHHCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSEIDQLAFELAKGVSEGGKSQLKSDAFKTKQKALKEKVQALLEKERVLLESNRENMQQL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RKQAAREYQQRVERSLESIEIHTDEWLKEGRVLIVEGQHSNGGSIEQNEERSVDLPSGGT
HHHHHHHHHHHHHHHHHHEECCHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCH
NHLLERFSESVLLAILITSVMALLLAYWLSHHVTGPLSELAGGHQKLAKGEFGVQLKEQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHCCCCCCHHHHHH
VKELKQILTGFNRMSLALANLSKKEQQMSQQQHLADLGQITRGIAHSLRNPLHTLGLLSE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QSTCSETLAEREKLNNKMQQKIALMDKSIQSLLTLSSHEVARDKAIPLNAIIQDVLLELS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ITGIKPKVMFDPQSIKLFVNGAESELRSILHAVMINAVEADPDAKQIKIELTQDVNAKKV
HCCCCCEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEE
IITDWGKGIDPLVKTQMFKPHVTTKTEGSGMGIYIAKRLIESHYDGEIQFDDNPQGGTIV
EEECCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEE
TLIFCRGEPGPDSSAKSNIDSNSDSNRKPSYQGKVKP
EEEEECCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]