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The map label for this gene is nhaR [H]

Identifier: 157960855

GI number: 157960855

Start: 1250909

End: 1251817

Strand: Direct

Name: nhaR [H]

Synonym: Spea_1027

Alternate gene names: 157960855

Gene position: 1250909-1251817 (Clockwise)

Preceding gene: 157960854

Following gene: 157960856

Centisome position: 24.17

GC content: 42.35

Gene sequence:

>909_bases
ATGGCTAATCTAAACTACAACCATCTCTATTACTTCTGGATGATCCAAAAGAAAGGAACTGTTGCAAAGGCTGCAGAGGC
GTTATGTTTAACCCCTCAAACGGTTACTGGACAAATCCGAGTATTGGAGGCCAGTCTTAAGGGAAGCTTATTTAAGCGAG
TAGGTCGTTCATTGGAGCCTACTGAACTGGGGGAATTGGTATTTCGTTATGCCGACAAGATGTTTAGCCTCAGTTATGAA
ATGTTAGATCTGCTGAACTATCAAAAAGATGAGAATATTTTATTTGAGGTAGGAATAGCTGCGGCGCTATCTAAAGCATT
AACGAGTCGAGTGTTATTGTCTGTCGTACCGAGTGATGGCTCAATGCACCTAGCTTGTTATGAGGCAACACATGAAGACT
TAATGACAAGACTGCGTGAGCATAAGTTGGATATGATTCTATCCGATTGTGCAGGGGAGAGTTTGAAGTATCCTGAGATC
TTATCTAAACAATTAGGTGAGTCGGGGGTCGCTTTTTTCTCTGCTGATACTTACTCAAAGCCTTTCCCGCAGTGTTTAGA
GCAGGGAAAATTACTTATTCCAGGAAGACGAACTTCACTTGGACAGCAGTTGGTTCGATGGTTCGATGAAAAAGCCTTAA
ATGTCAGTATTCTTGGTGAATTTGACGATGCGGCAATGATGAAATCGTTTGGATTCTTTAAGCAGGGGATCTTTGTGGCC
CCATCGATTTACAAGCAGGACATTCTTGCTCATGGTATGACTCTACTGGGTGAAACATCAGAAGTTAAAGAGGTCTACCA
TGTGATGTTTGCTGAACGTATGATCCAGCACCCAGCAGTTAAGCGCTTGTTAGAAACTGATTTTACAGAGTTGTTTGCGG
GAAAGGATTTAACCGTTCAACAGCTCTAG

Upstream 100 bases:

>100_bases
AGGTTTATTGGACTGTCAGCGTCTTAAGTAAGTTAAACTAAATTAACGAGGCAACTGAATAAGTTGCCTCTTTTTTATTT
ATATAACAGTAGTATTTATC

Downstream 100 bases:

>100_bases
CGCACCATTTACCCATCTGAACAAATAGGCGGCGAAGAGTAATCGGTTACCCTGTGTTATCAATATCGACACAAAGACTC
GGCAACTGATACACTAGCGA

Product: transcriptional activator NhaR

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MANLNYNHLYYFWMIQKKGTVAKAAEALCLTPQTVTGQIRVLEASLKGSLFKRVGRSLEPTELGELVFRYADKMFSLSYE
MLDLLNYQKDENILFEVGIAAALSKALTSRVLLSVVPSDGSMHLACYEATHEDLMTRLREHKLDMILSDCAGESLKYPEI
LSKQLGESGVAFFSADTYSKPFPQCLEQGKLLIPGRRTSLGQQLVRWFDEKALNVSILGEFDDAAMMKSFGFFKQGIFVA
PSIYKQDILAHGMTLLGETSEVKEVYHVMFAERMIQHPAVKRLLETDFTELFAGKDLTVQQL

Sequences:

>Translated_302_residues
MANLNYNHLYYFWMIQKKGTVAKAAEALCLTPQTVTGQIRVLEASLKGSLFKRVGRSLEPTELGELVFRYADKMFSLSYE
MLDLLNYQKDENILFEVGIAAALSKALTSRVLLSVVPSDGSMHLACYEATHEDLMTRLREHKLDMILSDCAGESLKYPEI
LSKQLGESGVAFFSADTYSKPFPQCLEQGKLLIPGRRTSLGQQLVRWFDEKALNVSILGEFDDAAMMKSFGFFKQGIFVA
PSIYKQDILAHGMTLLGETSEVKEVYHVMFAERMIQHPAVKRLLETDFTELFAGKDLTVQQL
>Mature_301_residues
ANLNYNHLYYFWMIQKKGTVAKAAEALCLTPQTVTGQIRVLEASLKGSLFKRVGRSLEPTELGELVFRYADKMFSLSYEM
LDLLNYQKDENILFEVGIAAALSKALTSRVLLSVVPSDGSMHLACYEATHEDLMTRLREHKLDMILSDCAGESLKYPEIL
SKQLGESGVAFFSADTYSKPFPQCLEQGKLLIPGRRTSLGQQLVRWFDEKALNVSILGEFDDAAMMKSFGFFKQGIFVAP
SIYKQDILAHGMTLLGETSEVKEVYHVMFAERMIQHPAVKRLLETDFTELFAGKDLTVQQL

Specific function: Plays a role in the positive regulation of nhaA (Probable) [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=295, Percent_Identity=56.6101694915254, Blast_Score=353, Evalue=6e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34036; Mature: 33905

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLNYNHLYYFWMIQKKGTVAKAAEALCLTPQTVTGQIRVLEASLKGSLFKRVGRSLEP
CCCCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCH
TELGELVFRYADKMFSLSYEMLDLLNYQKDENILFEVGIAAALSKALTSRVLLSVVPSDG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHEEECCCC
SMHLACYEATHEDLMTRLREHKLDMILSDCAGESLKYPEILSKQLGESGVAFFSADTYSK
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEECCCCCC
PFPQCLEQGKLLIPGRRTSLGQQLVRWFDEKALNVSILGEFDDAAMMKSFGFFKQGIFVA
CHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHCCCEEC
PSIYKQDILAHGMTLLGETSEVKEVYHVMFAERMIQHPAVKRLLETDFTELFAGKDLTVQ
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCC
QL
CC
>Mature Secondary Structure 
ANLNYNHLYYFWMIQKKGTVAKAAEALCLTPQTVTGQIRVLEASLKGSLFKRVGRSLEP
CCCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCH
TELGELVFRYADKMFSLSYEMLDLLNYQKDENILFEVGIAAALSKALTSRVLLSVVPSDG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHEEECCCC
SMHLACYEATHEDLMTRLREHKLDMILSDCAGESLKYPEILSKQLGESGVAFFSADTYSK
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEECCCCCC
PFPQCLEQGKLLIPGRRTSLGQQLVRWFDEKALNVSILGEFDDAAMMKSFGFFKQGIFVA
CHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHCCCEEC
PSIYKQDILAHGMTLLGETSEVKEVYHVMFAERMIQHPAVKRLLETDFTELFAGKDLTVQ
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCC
QL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]