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The map label for this gene is rcsC [H]

Identifier: 157960737

GI number: 157960737

Start: 1110408

End: 1114409

Strand: Reverse

Name: rcsC [H]

Synonym: Spea_0909

Alternate gene names: 157960737

Gene position: 1114409-1110408 (Counterclockwise)

Preceding gene: 157960738

Following gene: 157960736

Centisome position: 21.54

GC content: 43.08

Gene sequence:

>4002_bases
ATGCGTCAAGCGCTACTGATACTAATTCTATTTTCTCTGTCTTTTTCTGCGATAGCAGGTCAAGCAAAAAATGACACCGC
CGCGGCCACTGAAGGTCGAGTGGTTAGGGTCGGCTACCCAGCCGCGGATTGGCAGCCTTTTACTTATGTCAGTAAAGATG
GAAAAGTCATCGGCTTACTACCATCCATTCTGCAAGAGATCACCATAAATACCGGCTACCGCACAGAGAATGTAATCTAT
CCGAACTATGAAGAAGTTACTCAGGCTCTACGCCAAGGTGAAATTGACATCATCATGGGAGTATCAAAAACTCCCAGCCG
CTTGACTTGGCTAAGCTTTAGCTCACCACTCATGCTGGTACCTATTGCAGGTATCACTAATCAGAAAAATATTAACAATC
TATTAGAGCTAAAAGGTCAGCGCATCGCTGCAGAAAAAGGTTTCGCGATAAATGAACAGCTTAGAAGTTCAGCCAGCCAA
GTCGAAGTTCACAGCGCTCCCGACAGCCTCGCAGCTTATAAATCTGTTTTAACAGGAAGCTCAGATGCATACATAGGTAA
TGCGATTACCCTTGATTACCTGCATACCCACCAGGATGCACCTAATGAACTGTCTATACGCCTGCTGGCTGATGTGCCCT
TTGAGAGATTGCACCTTGCGAGCCAACTAAAAGACACCGAGCTCGTTAATCAGCTAAATGAGGGGCTAAAACAGATCCCA
AGTGAGACTTTTAAGAAACTCTATGACGCCTGGCTGACAACCTCTCAAGTTAAATATATTTACCAGCAACATAGTCTGAA
CTTAACTGAAGAGGAAATCGTAACCATTAGTGAGAAGAAAATCATTAAGGTACTTTACTCTACAGATAATTATCCTTATT
CCTTTATCAATGGTAAAGGTGCAATGGATGGTATGGGTCCAGAGCTCTTAAAAATAGCAGCCCAAAAGTTAAATATAACG
ATTGAAGCCACGCCGTTTAATGGAAATGATATTGAGGGACATCTTGCCTCGAATAGCTTCGAGATCATCCCATCCTATAC
TTGCGACCATAACATTTTACAGCTTATACACTGCACTTCGCCTTACATACAAGATCGCTTGATTGGGGTTGCAGCAAGTA
ACTTAACCAGCGCACAACTGGAGAACAGTACCAAATTAGGCTTACTAAGACGTCACAAACAACAAATGAATACGTCTAAG
GATTTTCCTGATGCAGATATCACTTATTTTGCTTCAACAAAACTGCTGATAAACGCTGTCATTAAAGGTCAGATACAAGT
TGGCATCATCCCTTTATCAAAGGCTAATTCTTTAGTCAGTTCAAAGTATTTAGGTCGAATAAATATTATCCCAAACCCTT
TGGGTAAACAAACTCACCCGGTGAGTTTTGGTGTTAATAAGAATAACCCTATTCTGCTGTCAATCTTGAATAAAGCAAAA
AACTCCATTCAAGAAGATGAGTTACGTACCATCATCAATAAATGGCATGATATCAATATCAACAGTGACTTTACCTTTGC
TAAAGTACCAAACTGGCTGCTGTTAGTGCTAGGGGGAGTTTTCAGTACTTTTTTGGCCATAGCTTACTCCAATAGAAAAC
TAAAAAATGAAATAGCGCAGCGGCACAGCATCGAAAAAGAGCTAAGGTTGGTTAATAGCAACTTTGGTGGCATAGTTGCA
CAGTTAGTACGCTATGGCGATGATGTTAATGACATTTCTTGGAGCTATGTTAGCGGCAATATTGAGAAATACTTGGGTTT
GACACCGGAACAACTCTATCAAACACCACAACTGCTTTTAGAGTTTTTACAGACACACGCTGATGATCATGAGTTTTTAA
ATGATATACAGCAGTCTCACCTTTCTGATTCTCTCTACACAACCCTCAAGCTTAACATTGACGGTAAGCTCTCTTGGTTC
CAACTCACGGGAGTCTGCACAAAAATCGATAAGAATCGGCATTGGACCTTCACCCTAGTCGATATTACTTTGCTTAAGCA
AAAGCAAGCTGAGCTAGATGAGGCGAGATTAATAGCAGAATCAGCAACCGAGGCCAAGTCTCGCTTTCTTGCCATGATGA
GCCATGAGATCCGTACGCCTATTAGCGGGATCCTGAGCCTACTGGAATTAATGGTTCCACACATCAACACACATGAGATC
AGTGGCATACATAAAAATCTGACTCATTCTGGTAATAACTTGCTCAACATCGTTAATGATGTTCTCGATTTCTCAAAAAT
CGAAGCGGGCAAGCTCGGATTAAGCCCCGCTGTATGCCAACTTAGCAGTTTTATTTGTGAATTAGCCCAGCCTCACATTG
TCCATGTCGAGCGTAAAGGTATTAAATTTAAGCTCTGGCTCGACCCTAAGCTAGCGTATTCACTAACCCTAGATCATTTG
CGCCTAAAACAGGTGCTAAACAACCTACTCAATAACGCTTCGAAGTTTACAACCGAGGGAGAGATCTGGTTATCGGTCGA
TCTCATATCTTCAACAGACACAGAGCAAACTATTGGTTTTGCCGTTACCGATACAGGCATAGGAATTAGTGAAAAAGATA
TCACTAAACTCTTTATTCCCTTTGAACAAGTCGATCTCAGTAGCGAGCGCCGTTTCAGCGGTACAGGTCTAGGCCTATCT
ATCTGTGAGCAGTTAGTCAAATTGATGGGAGGAGAGATCTCTGTCACCAGTACCCAAGGCCAAGGCAGTACTTTTCGCTT
TAGCCTGAGCTTCCCTATTGCAGCAGTTGAAGTGCCCGCTATTGTCAATAAGCGCTGTGGCGTAATGATGCTTGATGACA
GCGACTATGATGTGGTCTGTGAATACCTTAGAGCCTGGCAATCGACTCCTTATAACTTGCATTGTATCGACAATAAAGCC
GCCCTCGCAGCATACGCTGCCAAGGCGCAATTGCAGGTCATACTGTTGCCAGAAAGTTGGTGTGAACAACAAGCACTAAC
GCCAAGTTGGGCTAAACGCAACCTTGCTAATGTGCAGATTATTCAATTTAGAAGCCAGAGTATGCTCTCAGCAACTCCAA
CAGAACTTGGCTGGGTACTATCGGTCAACCCAATCATCCCTGAGCACTTGCTGCATCTCATCACTAATCCAGAGGTTTTT
GAGACCAAGTATGCAGTGACAGAGCCTAAAGTCGAACAGCAACTCACTCGCGAGCAGGCTATCAGCCAAAATAAGCTTAT
TCTCGTTGCGGAAGATCACCCTATTAATCAGGATGTTATTCAGATGCAGCTGAATAAATTAGGCTACTTTAGCGATATTT
TTGACGACGGCCAGCAAGCGTTGACGGCCTATAAACAGAATAAATACAACCTCGTTTTGACCGACTGCCACATGCCTGAA
CTCGATGGCTATGGTCTAGTGAGTGCCATTAGAGAGCATGAACAACAAGAAAAACTAACCCGCCTCGCAGTTATCGCCCT
CACGGCCAATGCGATTTCGAGTGAGAAAGCCCGTTGCCATCAATTTGGCTTCGATGACTACTTAATAAAACCGGTAACCC
TAGAGCAACTGCAACGAGTGCTTAGTGAACACTTAGTGATGACTCAGTCTTCCTCAAACAGTAATGAGATGCGCACTGAT
GGGATGCTGCGTGAGCCGCCTTTACCAGCCACTCTGACTAACTTAGCAATAGATCGAATAGATGCGAGCATGTCCAATGT
TATCGATATCGATGCACTAGAAGCCAATTTCGGCGACCGACAGCTTTGCATCAATTTACTGAGTAAATTTATCATCACCA
GCAAGGATGACATTCAGCTACTAAGCCAAGCAATTACCGAACAAAACTTTGAAATGACAGCCCATATTGCTCATAAGTTC
AAAGGCGCCGCTGGGGTAATTGAGTGTGAACGGCTCGTTGCGACTTGCTCCAACATAGAAACGGCGGCTTCGACTCAAGA
TATTAAAGTATTAAAGGAATATCTTGTACAGATAGAACAATTAATAGAGCAGATCTCTAATCAGGTAAACCAGTTAACAT
GA

Upstream 100 bases:

>100_bases
TTAAAGCATTCTTTACTGCAATAACCGCGAGTGCCTGCAGCCTGTGCAAAAAGCATCTCATGCTAATTAATTACTGTCGA
AACTCGATATAGGCTGCAAA

Downstream 100 bases:

>100_bases
AAATTTTACTGATTGAAGATCACTTATTTCAGCGAGAAGCGATGCAAATGCAACTTGAGCTGATCACCTCACCTAAGATT
TCGCTGATTAGAACCGCAGC

Product: Hpt sensor hybrid histidine kinase

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 1333; Mature: 1333

Protein sequence:

>1333_residues
MRQALLILILFSLSFSAIAGQAKNDTAAATEGRVVRVGYPAADWQPFTYVSKDGKVIGLLPSILQEITINTGYRTENVIY
PNYEEVTQALRQGEIDIIMGVSKTPSRLTWLSFSSPLMLVPIAGITNQKNINNLLELKGQRIAAEKGFAINEQLRSSASQ
VEVHSAPDSLAAYKSVLTGSSDAYIGNAITLDYLHTHQDAPNELSIRLLADVPFERLHLASQLKDTELVNQLNEGLKQIP
SETFKKLYDAWLTTSQVKYIYQQHSLNLTEEEIVTISEKKIIKVLYSTDNYPYSFINGKGAMDGMGPELLKIAAQKLNIT
IEATPFNGNDIEGHLASNSFEIIPSYTCDHNILQLIHCTSPYIQDRLIGVAASNLTSAQLENSTKLGLLRRHKQQMNTSK
DFPDADITYFASTKLLINAVIKGQIQVGIIPLSKANSLVSSKYLGRINIIPNPLGKQTHPVSFGVNKNNPILLSILNKAK
NSIQEDELRTIINKWHDININSDFTFAKVPNWLLLVLGGVFSTFLAIAYSNRKLKNEIAQRHSIEKELRLVNSNFGGIVA
QLVRYGDDVNDISWSYVSGNIEKYLGLTPEQLYQTPQLLLEFLQTHADDHEFLNDIQQSHLSDSLYTTLKLNIDGKLSWF
QLTGVCTKIDKNRHWTFTLVDITLLKQKQAELDEARLIAESATEAKSRFLAMMSHEIRTPISGILSLLELMVPHINTHEI
SGIHKNLTHSGNNLLNIVNDVLDFSKIEAGKLGLSPAVCQLSSFICELAQPHIVHVERKGIKFKLWLDPKLAYSLTLDHL
RLKQVLNNLLNNASKFTTEGEIWLSVDLISSTDTEQTIGFAVTDTGIGISEKDITKLFIPFEQVDLSSERRFSGTGLGLS
ICEQLVKLMGGEISVTSTQGQGSTFRFSLSFPIAAVEVPAIVNKRCGVMMLDDSDYDVVCEYLRAWQSTPYNLHCIDNKA
ALAAYAAKAQLQVILLPESWCEQQALTPSWAKRNLANVQIIQFRSQSMLSATPTELGWVLSVNPIIPEHLLHLITNPEVF
ETKYAVTEPKVEQQLTREQAISQNKLILVAEDHPINQDVIQMQLNKLGYFSDIFDDGQQALTAYKQNKYNLVLTDCHMPE
LDGYGLVSAIREHEQQEKLTRLAVIALTANAISSEKARCHQFGFDDYLIKPVTLEQLQRVLSEHLVMTQSSSNSNEMRTD
GMLREPPLPATLTNLAIDRIDASMSNVIDIDALEANFGDRQLCINLLSKFIITSKDDIQLLSQAITEQNFEMTAHIAHKF
KGAAGVIECERLVATCSNIETAASTQDIKVLKEYLVQIEQLIEQISNQVNQLT

Sequences:

>Translated_1333_residues
MRQALLILILFSLSFSAIAGQAKNDTAAATEGRVVRVGYPAADWQPFTYVSKDGKVIGLLPSILQEITINTGYRTENVIY
PNYEEVTQALRQGEIDIIMGVSKTPSRLTWLSFSSPLMLVPIAGITNQKNINNLLELKGQRIAAEKGFAINEQLRSSASQ
VEVHSAPDSLAAYKSVLTGSSDAYIGNAITLDYLHTHQDAPNELSIRLLADVPFERLHLASQLKDTELVNQLNEGLKQIP
SETFKKLYDAWLTTSQVKYIYQQHSLNLTEEEIVTISEKKIIKVLYSTDNYPYSFINGKGAMDGMGPELLKIAAQKLNIT
IEATPFNGNDIEGHLASNSFEIIPSYTCDHNILQLIHCTSPYIQDRLIGVAASNLTSAQLENSTKLGLLRRHKQQMNTSK
DFPDADITYFASTKLLINAVIKGQIQVGIIPLSKANSLVSSKYLGRINIIPNPLGKQTHPVSFGVNKNNPILLSILNKAK
NSIQEDELRTIINKWHDININSDFTFAKVPNWLLLVLGGVFSTFLAIAYSNRKLKNEIAQRHSIEKELRLVNSNFGGIVA
QLVRYGDDVNDISWSYVSGNIEKYLGLTPEQLYQTPQLLLEFLQTHADDHEFLNDIQQSHLSDSLYTTLKLNIDGKLSWF
QLTGVCTKIDKNRHWTFTLVDITLLKQKQAELDEARLIAESATEAKSRFLAMMSHEIRTPISGILSLLELMVPHINTHEI
SGIHKNLTHSGNNLLNIVNDVLDFSKIEAGKLGLSPAVCQLSSFICELAQPHIVHVERKGIKFKLWLDPKLAYSLTLDHL
RLKQVLNNLLNNASKFTTEGEIWLSVDLISSTDTEQTIGFAVTDTGIGISEKDITKLFIPFEQVDLSSERRFSGTGLGLS
ICEQLVKLMGGEISVTSTQGQGSTFRFSLSFPIAAVEVPAIVNKRCGVMMLDDSDYDVVCEYLRAWQSTPYNLHCIDNKA
ALAAYAAKAQLQVILLPESWCEQQALTPSWAKRNLANVQIIQFRSQSMLSATPTELGWVLSVNPIIPEHLLHLITNPEVF
ETKYAVTEPKVEQQLTREQAISQNKLILVAEDHPINQDVIQMQLNKLGYFSDIFDDGQQALTAYKQNKYNLVLTDCHMPE
LDGYGLVSAIREHEQQEKLTRLAVIALTANAISSEKARCHQFGFDDYLIKPVTLEQLQRVLSEHLVMTQSSSNSNEMRTD
GMLREPPLPATLTNLAIDRIDASMSNVIDIDALEANFGDRQLCINLLSKFIITSKDDIQLLSQAITEQNFEMTAHIAHKF
KGAAGVIECERLVATCSNIETAASTQDIKVLKEYLVQIEQLIEQISNQVNQLT
>Mature_1333_residues
MRQALLILILFSLSFSAIAGQAKNDTAAATEGRVVRVGYPAADWQPFTYVSKDGKVIGLLPSILQEITINTGYRTENVIY
PNYEEVTQALRQGEIDIIMGVSKTPSRLTWLSFSSPLMLVPIAGITNQKNINNLLELKGQRIAAEKGFAINEQLRSSASQ
VEVHSAPDSLAAYKSVLTGSSDAYIGNAITLDYLHTHQDAPNELSIRLLADVPFERLHLASQLKDTELVNQLNEGLKQIP
SETFKKLYDAWLTTSQVKYIYQQHSLNLTEEEIVTISEKKIIKVLYSTDNYPYSFINGKGAMDGMGPELLKIAAQKLNIT
IEATPFNGNDIEGHLASNSFEIIPSYTCDHNILQLIHCTSPYIQDRLIGVAASNLTSAQLENSTKLGLLRRHKQQMNTSK
DFPDADITYFASTKLLINAVIKGQIQVGIIPLSKANSLVSSKYLGRINIIPNPLGKQTHPVSFGVNKNNPILLSILNKAK
NSIQEDELRTIINKWHDININSDFTFAKVPNWLLLVLGGVFSTFLAIAYSNRKLKNEIAQRHSIEKELRLVNSNFGGIVA
QLVRYGDDVNDISWSYVSGNIEKYLGLTPEQLYQTPQLLLEFLQTHADDHEFLNDIQQSHLSDSLYTTLKLNIDGKLSWF
QLTGVCTKIDKNRHWTFTLVDITLLKQKQAELDEARLIAESATEAKSRFLAMMSHEIRTPISGILSLLELMVPHINTHEI
SGIHKNLTHSGNNLLNIVNDVLDFSKIEAGKLGLSPAVCQLSSFICELAQPHIVHVERKGIKFKLWLDPKLAYSLTLDHL
RLKQVLNNLLNNASKFTTEGEIWLSVDLISSTDTEQTIGFAVTDTGIGISEKDITKLFIPFEQVDLSSERRFSGTGLGLS
ICEQLVKLMGGEISVTSTQGQGSTFRFSLSFPIAAVEVPAIVNKRCGVMMLDDSDYDVVCEYLRAWQSTPYNLHCIDNKA
ALAAYAAKAQLQVILLPESWCEQQALTPSWAKRNLANVQIIQFRSQSMLSATPTELGWVLSVNPIIPEHLLHLITNPEVF
ETKYAVTEPKVEQQLTREQAISQNKLILVAEDHPINQDVIQMQLNKLGYFSDIFDDGQQALTAYKQNKYNLVLTDCHMPE
LDGYGLVSAIREHEQQEKLTRLAVIALTANAISSEKARCHQFGFDDYLIKPVTLEQLQRVLSEHLVMTQSSSNSNEMRTD
GMLREPPLPATLTNLAIDRIDASMSNVIDIDALEANFGDRQLCINLLSKFIITSKDDIQLLSQAITEQNFEMTAHIAHKF
KGAAGVIECERLVATCSNIETAASTQDIKVLKEYLVQIEQLIEQISNQVNQLT

Specific function: Member of the two-component regulatory system RcsC/RcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with RcsF, RcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=549, Percent_Identity=33.1511839708561, Blast_Score=246, Evalue=9e-66,
Organism=Escherichia coli, GI1789149, Length=538, Percent_Identity=31.5985130111524, Blast_Score=208, Evalue=2e-54,
Organism=Escherichia coli, GI1788713, Length=898, Percent_Identity=24.0534521158129, Blast_Score=176, Evalue=7e-45,
Organism=Escherichia coli, GI87081816, Length=271, Percent_Identity=39.4833948339483, Blast_Score=153, Evalue=8e-38,
Organism=Escherichia coli, GI48994928, Length=398, Percent_Identity=30.4020100502513, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI1786783, Length=241, Percent_Identity=26.1410788381743, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788393, Length=216, Percent_Identity=26.8518518518519, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=27.6315789473684, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI87082128, Length=234, Percent_Identity=26.9230769230769, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1789402, Length=140, Percent_Identity=32.1428571428571, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1786912, Length=268, Percent_Identity=26.1194029850746, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1787894, Length=233, Percent_Identity=25.7510729613734, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1788549, Length=336, Percent_Identity=23.5119047619048, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 148728; Mature: 148728

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQALLILILFSLSFSAIAGQAKNDTAAATEGRVVRVGYPAADWQPFTYVSKDGKVIGLL
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEECCCCCEEEHH
PSILQEITINTGYRTENVIYPNYEEVTQALRQGEIDIIMGVSKTPSRLTWLSFSSPLMLV
HHHHHHHCCCCCCCCCCEECCCHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCEEEE
PIAGITNQKNINNLLELKGQRIAAEKGFAINEQLRSSASQVEVHSAPDSLAAYKSVLTGS
EECCCCCCCHHHHHHHHCCCEEECCCCCEECHHHHCCHHHEEEECCCHHHHHHHHHHCCC
SDAYIGNAITLDYLHTHQDAPNELSIRLLADVPFERLHLASQLKDTELVNQLNEGLKQIP
CCCEECCEEEEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCH
SETFKKLYDAWLTTSQVKYIYQQHSLNLTEEEIVTISEKKIIKVLYSTDNYPYSFINGKG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEECHHHEEEEEECCCCCCEEEECCCC
AMDGMGPELLKIAAQKLNITIEATPFNGNDIEGHLASNSFEIIPSYTCDHNILQLIHCTS
CCCCCCHHHHHHHHHHEEEEEEEECCCCCCCCCEECCCCEEEEECCCCCHHHHHHHHCCC
PYIQDRLIGVAASNLTSAQLENSTKLGLLRRHKQQMNTSKDFPDADITYFASTKLLINAV
HHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHH
IKGQIQVGIIPLSKANSLVSSKYLGRINIIPNPLGKQTHPVSFGVNKNNPILLSILNKAK
HCCEEEEEEEECCHHHHHHHHHCCCEEEECCCCCCCCCCCEEECCCCCCCEEEEEHHHHH
NSIQEDELRTIINKWHDININSDFTFAKVPNWLLLVLGGVFSTFLAIAYSNRKLKNEIAQ
HCCCHHHHHHHHHHHCCCCCCCCEEHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
RHSIEKELRLVNSNFGGIVAQLVRYGDDVNDISWSYVSGNIEKYLGLTPEQLYQTPQLLL
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHCCCHHHHHCCHHHHH
EFLQTHADDHEFLNDIQQSHLSDSLYTTLKLNIDGKLSWFQLTGVCTKIDKNRHWTFTLV
HHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEEEECHHEEECCCCCEEEEEE
DITLLKQKQAELDEARLIAESATEAKSRFLAMMSHEIRTPISGILSLLELMVPHINTHEI
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHH
SGIHKNLTHSGNNLLNIVNDVLDFSKIEAGKLGLSPAVCQLSSFICELAQPHIVHVERKG
CCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECC
IKFKLWLDPKLAYSLTLDHLRLKQVLNNLLNNASKFTTEGEIWLSVDLISSTDTEQTIGF
EEEEEEECCCEEEHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEEEEECCCCCCHHCEE
AVTDTGIGISEKDITKLFIPFEQVDLSSERRFSGTGLGLSICEQLVKLMGGEISVTSTQG
EEECCCCCCCCCCCCEEECCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCC
QGSTFRFSLSFPIAAVEVPAIVNKRCGVMMLDDSDYDVVCEYLRAWQSTPYNLHCIDNKA
CCCEEEEEEECCEEEEECCHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCH
ALAAYAAKAQLQVILLPESWCEQQALTPSWAKRNLANVQIIQFRSQSMLSATPTELGWVL
HHHHHHHCCEEEEEEECHHHHHHCCCCHHHHHCCCCCEEEEEECCCHHHCCCCCCCCEEE
SVNPIIPEHLLHLITNPEVFETKYAVTEPKVEQQLTREQAISQNKLILVAEDHPINQDVI
EECCCCHHHHHHHHCCCCHHCCEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHH
QMQLNKLGYFSDIFDDGQQALTAYKQNKYNLVLTDCHMPELDGYGLVSAIREHEQQEKLT
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
RLAVIALTANAISSEKARCHQFGFDDYLIKPVTLEQLQRVLSEHLVMTQSSSNSNEMRTD
HHHHHEEEHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHEEECCCCCCCCCCCC
GMLREPPLPATLTNLAIDRIDASMSNVIDIDALEANFGDRQLCINLLSKFIITSKDDIQL
CCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHH
LSQAITEQNFEMTAHIAHKFKGAAGVIECERLVATCSNIETAASTQDIKVLKEYLVQIEQ
HHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHH
LIEQISNQVNQLT
HHHHHHHHHHCCC
>Mature Secondary Structure
MRQALLILILFSLSFSAIAGQAKNDTAAATEGRVVRVGYPAADWQPFTYVSKDGKVIGLL
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEECCCCCEEEHH
PSILQEITINTGYRTENVIYPNYEEVTQALRQGEIDIIMGVSKTPSRLTWLSFSSPLMLV
HHHHHHHCCCCCCCCCCEECCCHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCEEEE
PIAGITNQKNINNLLELKGQRIAAEKGFAINEQLRSSASQVEVHSAPDSLAAYKSVLTGS
EECCCCCCCHHHHHHHHCCCEEECCCCCEECHHHHCCHHHEEEECCCHHHHHHHHHHCCC
SDAYIGNAITLDYLHTHQDAPNELSIRLLADVPFERLHLASQLKDTELVNQLNEGLKQIP
CCCEECCEEEEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCH
SETFKKLYDAWLTTSQVKYIYQQHSLNLTEEEIVTISEKKIIKVLYSTDNYPYSFINGKG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEECHHHEEEEEECCCCCCEEEECCCC
AMDGMGPELLKIAAQKLNITIEATPFNGNDIEGHLASNSFEIIPSYTCDHNILQLIHCTS
CCCCCCHHHHHHHHHHEEEEEEEECCCCCCCCCEECCCCEEEEECCCCCHHHHHHHHCCC
PYIQDRLIGVAASNLTSAQLENSTKLGLLRRHKQQMNTSKDFPDADITYFASTKLLINAV
HHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHH
IKGQIQVGIIPLSKANSLVSSKYLGRINIIPNPLGKQTHPVSFGVNKNNPILLSILNKAK
HCCEEEEEEEECCHHHHHHHHHCCCEEEECCCCCCCCCCCEEECCCCCCCEEEEEHHHHH
NSIQEDELRTIINKWHDININSDFTFAKVPNWLLLVLGGVFSTFLAIAYSNRKLKNEIAQ
HCCCHHHHHHHHHHHCCCCCCCCEEHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
RHSIEKELRLVNSNFGGIVAQLVRYGDDVNDISWSYVSGNIEKYLGLTPEQLYQTPQLLL
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHCCCHHHHHCCHHHHH
EFLQTHADDHEFLNDIQQSHLSDSLYTTLKLNIDGKLSWFQLTGVCTKIDKNRHWTFTLV
HHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEEEECHHEEECCCCCEEEEEE
DITLLKQKQAELDEARLIAESATEAKSRFLAMMSHEIRTPISGILSLLELMVPHINTHEI
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHH
SGIHKNLTHSGNNLLNIVNDVLDFSKIEAGKLGLSPAVCQLSSFICELAQPHIVHVERKG
CCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECC
IKFKLWLDPKLAYSLTLDHLRLKQVLNNLLNNASKFTTEGEIWLSVDLISSTDTEQTIGF
EEEEEEECCCEEEHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEEEEECCCCCCHHCEE
AVTDTGIGISEKDITKLFIPFEQVDLSSERRFSGTGLGLSICEQLVKLMGGEISVTSTQG
EEECCCCCCCCCCCCEEECCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCC
QGSTFRFSLSFPIAAVEVPAIVNKRCGVMMLDDSDYDVVCEYLRAWQSTPYNLHCIDNKA
CCCEEEEEEECCEEEEECCHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCH
ALAAYAAKAQLQVILLPESWCEQQALTPSWAKRNLANVQIIQFRSQSMLSATPTELGWVL
HHHHHHHCCEEEEEEECHHHHHHCCCCHHHHHCCCCCEEEEEECCCHHHCCCCCCCCEEE
SVNPIIPEHLLHLITNPEVFETKYAVTEPKVEQQLTREQAISQNKLILVAEDHPINQDVI
EECCCCHHHHHHHHCCCCHHCCEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHH
QMQLNKLGYFSDIFDDGQQALTAYKQNKYNLVLTDCHMPELDGYGLVSAIREHEQQEKLT
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
RLAVIALTANAISSEKARCHQFGFDDYLIKPVTLEQLQRVLSEHLVMTQSSSNSNEMRTD
HHHHHEEEHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHEEECCCCCCCCCCCC
GMLREPPLPATLTNLAIDRIDASMSNVIDIDALEANFGDRQLCINLLSKFIITSKDDIQL
CCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHH
LSQAITEQNFEMTAHIAHKFKGAAGVIECERLVATCSNIETAASTQDIKVLKEYLVQIEQ
HHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHH
LIEQISNQVNQLT
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2404948; 8366025; 9097040; 9278503; 11758943; 11309126; 13129944 [H]