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The map label for this gene is atoS [C]

Identifier: 157960549

GI number: 157960549

Start: 890950

End: 892977

Strand: Reverse

Name: atoS [C]

Synonym: Spea_0721

Alternate gene names: 157960549

Gene position: 892977-890950 (Counterclockwise)

Preceding gene: 157960552

Following gene: 157960548

Centisome position: 17.26

GC content: 49.21

Gene sequence:

>2028_bases
ATGAAAATATTTGTTAACTTAATTTGCAGCCTCTGCACACTTTGTGCACTTGGCTTAGCGGGGTTATCGCTCCCCGCGCA
CGCTGCAGACTCCCACCAAAATCAAAGTATCGTCTTCGGCGTTCACTCAAAGACCGCCCCCCTTGAGTGGCGCAATAATG
GCGTAGACCAAGGCTTCAACCTCGAGTTGATGGATCGTATCGGTCAGCTCATGGGCAAGCGCATCATCATCCGCCGTAAG
AGCTTCCAGCAGCTACTTAAAGATGTGCACGACCGTGACTCGCTCATTGATGTCATCGCCGTGGTAAGCCCAATTACCAT
AGATAGAGAGCTGAGTCAGTCAGACCCCATTTATGCCACTCACGCAAAAGCTTACACACTTCAAGGTAAGTCGTTTATCA
ATGGCTGGAATGATCTTGAAGGCAAACGGGTAGCGATTAAGAAAGGCGCCTTCGTCGATGTCTATATCTCAGGTAAGAAA
CAAGACTTTACCCGCGTCGATGTCGACCTCTATGAGACAGGCTTCCAGCTGCTTATAAAAGGTGAGGTCGATGTGGTCAT
CGCCGAAAACTTTGTCGCCAGACGCCTAATGCCGCTGTACCCATCAATTAGAAGCTCGAGCGATCCGCTTATCTATGGTG
CATTTAACTTCGTCAGTAACTATAAAAACGCTGAAATGATGGCGCAAATCAACGACGCGCTTAGACAGTTAAAGCTATCT
GGCGAGTACGACCGATTAGTCAATAAGTGGTTTGGTACCGGCCGCGAAAAAGTCGACCTGAATTCGGCACAGAAGAAGAT
GCTCTCCTTAGCCATTTTTGTCAGCCTGCTTTCCGCCGTCGGCATGCTGCTGACTGGCTATATCAGTCTGAGTCTACGTA
GACGCTCTAAAGCGCTAAAAGTGGAGTTACTCCAGCGTAAGAAAGCCGAAGAGGCGATATCGAACTTATCGAAGCAGTTC
CAGTCGGTACTCGACGGGATCCCCCACGGCGTCACCCTGTTCAATCGAGACGGTGAATGCCTATGGAGCAACGATAACAA
TAACGACCTGCTGACCAGTCCAGAGTTTCACTATATTGATGGCGCAGCCTTTAACTTAGCGAATGCTCTTTCCGATGCGC
TTGTCGAGCAGAAGTCACAAACCGCCGATATGCAGGTTAATAATCAGTATTGGCAGCTGCAGCTTCACCCTATTAGCCAA
CAGCAGGTGGTGATTTTGCTTGAGGAAGCCACCGAACAACATAGATTGCGCCAAGCCAATGACGAAGCCAGCCGCCTCGC
CTCTCTAGGTGAGCTATCGGCGGGGATTGCCCATGAGATCAATAACCCGACGGGCATTATCATTCATTCGATTGCCTTTA
TTAGCGATGCCCTTAAAGATCTATCTGAAGCCAGTGATAACTATCAAAGACAAAACCCGTTTTGGACTGTAGCGGGCATG
GCGCCCGACAGTGCCATGAACGAGCTAGACGTGAGTAGTCAGTCTATTAATGAGGGGGCCGAGCGCATAAGCCGTATCGT
AAACGACTTAAAACGCTACGCTTTGCCGACTATAGCTAACGAGTATCAGCCAATCAGTGTTAATGAAGTGGTGGAGGTAT
CGCTGCGCCTCACAGCCAATCAGACCAAGATATTTAACGTCACTACCGATTTACTGCTCCCAAGCCCAGTTGTTATGGGG
GATGCCCAGCAACTGCATCAAGTACTGATCAATCTTATCCAAAACGCCTGCCATGCCATCAGGCAAGATGCTGAGTGCTA
TGAGTGCAAGGAACACATTAATATCCAGACCTGTGTCGAAGATAAACATATCTGCCTAGTGATCAGTGATAAAGGCGCCG
GAATGGATAGCGCCACCCTACAACGCATTACCGAACCTTTCTTTACTACGCGCCGTTCAAGTGGCGGCACAGGACTTGGC
CTCTCAGTGTGTAGCCGCATCATTAAAGAGCACAAGGCCGACATGCAGATCACCTCGCGCCTAGGCAAAGGCACTGTGAT
AAAAATACGCTTTCCTTTGGAGTACTAA

Upstream 100 bases:

>100_bases
CAAGCCTATGATTCTGCGCCTGTTGCAGCCTAAGGAGTTCCTTAGTAAATCGAGAAACCCCGCACAGTTATGCTGTATAA
GCTCATGCTAAGATTTGATT

Downstream 100 bases:

>100_bases
TGAAACTCGCCAGAAATATTCTTCTTGTTGACGATGAAGCCTCTTGGCTTAGAACACTCTCCATCACGCTTAATCGTCTC
GTGCCAGAAGCGACTATCGA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 675; Mature: 675

Protein sequence:

>675_residues
MKIFVNLICSLCTLCALGLAGLSLPAHAADSHQNQSIVFGVHSKTAPLEWRNNGVDQGFNLELMDRIGQLMGKRIIIRRK
SFQQLLKDVHDRDSLIDVIAVVSPITIDRELSQSDPIYATHAKAYTLQGKSFINGWNDLEGKRVAIKKGAFVDVYISGKK
QDFTRVDVDLYETGFQLLIKGEVDVVIAENFVARRLMPLYPSIRSSSDPLIYGAFNFVSNYKNAEMMAQINDALRQLKLS
GEYDRLVNKWFGTGREKVDLNSAQKKMLSLAIFVSLLSAVGMLLTGYISLSLRRRSKALKVELLQRKKAEEAISNLSKQF
QSVLDGIPHGVTLFNRDGECLWSNDNNNDLLTSPEFHYIDGAAFNLANALSDALVEQKSQTADMQVNNQYWQLQLHPISQ
QQVVILLEEATEQHRLRQANDEASRLASLGELSAGIAHEINNPTGIIIHSIAFISDALKDLSEASDNYQRQNPFWTVAGM
APDSAMNELDVSSQSINEGAERISRIVNDLKRYALPTIANEYQPISVNEVVEVSLRLTANQTKIFNVTTDLLLPSPVVMG
DAQQLHQVLINLIQNACHAIRQDAECYECKEHINIQTCVEDKHICLVISDKGAGMDSATLQRITEPFFTTRRSSGGTGLG
LSVCSRIIKEHKADMQITSRLGKGTVIKIRFPLEY

Sequences:

>Translated_675_residues
MKIFVNLICSLCTLCALGLAGLSLPAHAADSHQNQSIVFGVHSKTAPLEWRNNGVDQGFNLELMDRIGQLMGKRIIIRRK
SFQQLLKDVHDRDSLIDVIAVVSPITIDRELSQSDPIYATHAKAYTLQGKSFINGWNDLEGKRVAIKKGAFVDVYISGKK
QDFTRVDVDLYETGFQLLIKGEVDVVIAENFVARRLMPLYPSIRSSSDPLIYGAFNFVSNYKNAEMMAQINDALRQLKLS
GEYDRLVNKWFGTGREKVDLNSAQKKMLSLAIFVSLLSAVGMLLTGYISLSLRRRSKALKVELLQRKKAEEAISNLSKQF
QSVLDGIPHGVTLFNRDGECLWSNDNNNDLLTSPEFHYIDGAAFNLANALSDALVEQKSQTADMQVNNQYWQLQLHPISQ
QQVVILLEEATEQHRLRQANDEASRLASLGELSAGIAHEINNPTGIIIHSIAFISDALKDLSEASDNYQRQNPFWTVAGM
APDSAMNELDVSSQSINEGAERISRIVNDLKRYALPTIANEYQPISVNEVVEVSLRLTANQTKIFNVTTDLLLPSPVVMG
DAQQLHQVLINLIQNACHAIRQDAECYECKEHINIQTCVEDKHICLVISDKGAGMDSATLQRITEPFFTTRRSSGGTGLG
LSVCSRIIKEHKADMQITSRLGKGTVIKIRFPLEY
>Mature_675_residues
MKIFVNLICSLCTLCALGLAGLSLPAHAADSHQNQSIVFGVHSKTAPLEWRNNGVDQGFNLELMDRIGQLMGKRIIIRRK
SFQQLLKDVHDRDSLIDVIAVVSPITIDRELSQSDPIYATHAKAYTLQGKSFINGWNDLEGKRVAIKKGAFVDVYISGKK
QDFTRVDVDLYETGFQLLIKGEVDVVIAENFVARRLMPLYPSIRSSSDPLIYGAFNFVSNYKNAEMMAQINDALRQLKLS
GEYDRLVNKWFGTGREKVDLNSAQKKMLSLAIFVSLLSAVGMLLTGYISLSLRRRSKALKVELLQRKKAEEAISNLSKQF
QSVLDGIPHGVTLFNRDGECLWSNDNNNDLLTSPEFHYIDGAAFNLANALSDALVEQKSQTADMQVNNQYWQLQLHPISQ
QQVVILLEEATEQHRLRQANDEASRLASLGELSAGIAHEINNPTGIIIHSIAFISDALKDLSEASDNYQRQNPFWTVAGM
APDSAMNELDVSSQSINEGAERISRIVNDLKRYALPTIANEYQPISVNEVVEVSLRLTANQTKIFNVTTDLLLPSPVVMG
DAQQLHQVLINLIQNACHAIRQDAECYECKEHINIQTCVEDKHICLVISDKGAGMDSATLQRITEPFFTTRRSSGGTGLG
LSVCSRIIKEHKADMQITSRLGKGTVIKIRFPLEY

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc; May Activate Atoc By Phosphorylation. [C]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=276, Percent_Identity=28.6231884057971, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1790436, Length=253, Percent_Identity=28.4584980237154, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786600, Length=382, Percent_Identity=20.9424083769633, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87081816, Length=275, Percent_Identity=24, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1787085, Length=247, Percent_Identity=25.1012145748988, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1788393, Length=252, Percent_Identity=21.4285714285714, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787088, Length=247, Percent_Identity=25.1012145748988, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75221; Mature: 75221

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIFVNLICSLCTLCALGLAGLSLPAHAADSHQNQSIVFGVHSKTAPLEWRNNGVDQGFN
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
LELMDRIGQLMGKRIIIRRKSFQQLLKDVHDRDSLIDVIAVVSPITIDRELSQSDPIYAT
HHHHHHHHHHHCCEEEEEHHHHHHHHHHHHCHHHHHHHHHHHCCCEECCCCCCCCCEEEE
HAKAYTLQGKSFINGWNDLEGKRVAIKKGAFVDVYISGKKQDFTRVDVDLYETGFQLLIK
CCEEEEECCHHHHCCCCCCCCCEEEEECCCEEEEEECCCCCCCEEEEHHHHHCCEEEEEE
GEVDVVIAENFVARRLMPLYPSIRSSSDPLIYGAFNFVSNYKNAEMMAQINDALRQLKLS
CCEEEEEECHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHCC
GEYDRLVNKWFGTGREKVDLNSAQKKMLSLAIFVSLLSAVGMLLTGYISLSLRRRSKALK
CHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VELLQRKKAEEAISNLSKQFQSVLDGIPHGVTLFNRDGECLWSNDNNNDLLTSPEFHYID
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCEEEC
GAAFNLANALSDALVEQKSQTADMQVNNQYWQLQLHPISQQQVVILLEEATEQHRLRQAN
CHHHHHHHHHHHHHHHHHHHCCCEEECCEEEEEEEEECCCCEEEEEEHHHHHHHHHHHCC
DEASRLASLGELSAGIAHEINNPTGIIIHSIAFISDALKDLSEASDNYQRQNPFWTVAGM
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECC
APDSAMNELDVSSQSINEGAERISRIVNDLKRYALPTIANEYQPISVNEVVEVSLRLTAN
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCHHHHEEEEEEEEEC
QTKIFNVTTDLLLPSPVVMGDAQQLHQVLINLIQNACHAIRQDAECYECKEHINIQTCVE
CEEEEEEEHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEC
DKHICLVISDKGAGMDSATLQRITEPFFTTRRSSGGTGLGLSVCSRIIKEHKADMQITSR
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHH
LGKGTVIKIRFPLEY
CCCCCEEEEEECCCC
>Mature Secondary Structure
MKIFVNLICSLCTLCALGLAGLSLPAHAADSHQNQSIVFGVHSKTAPLEWRNNGVDQGFN
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
LELMDRIGQLMGKRIIIRRKSFQQLLKDVHDRDSLIDVIAVVSPITIDRELSQSDPIYAT
HHHHHHHHHHHCCEEEEEHHHHHHHHHHHHCHHHHHHHHHHHCCCEECCCCCCCCCEEEE
HAKAYTLQGKSFINGWNDLEGKRVAIKKGAFVDVYISGKKQDFTRVDVDLYETGFQLLIK
CCEEEEECCHHHHCCCCCCCCCEEEEECCCEEEEEECCCCCCCEEEEHHHHHCCEEEEEE
GEVDVVIAENFVARRLMPLYPSIRSSSDPLIYGAFNFVSNYKNAEMMAQINDALRQLKLS
CCEEEEEECHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHCC
GEYDRLVNKWFGTGREKVDLNSAQKKMLSLAIFVSLLSAVGMLLTGYISLSLRRRSKALK
CHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VELLQRKKAEEAISNLSKQFQSVLDGIPHGVTLFNRDGECLWSNDNNNDLLTSPEFHYID
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCEEEC
GAAFNLANALSDALVEQKSQTADMQVNNQYWQLQLHPISQQQVVILLEEATEQHRLRQAN
CHHHHHHHHHHHHHHHHHHHCCCEEECCEEEEEEEEECCCCEEEEEEHHHHHHHHHHHCC
DEASRLASLGELSAGIAHEINNPTGIIIHSIAFISDALKDLSEASDNYQRQNPFWTVAGM
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECC
APDSAMNELDVSSQSINEGAERISRIVNDLKRYALPTIANEYQPISVNEVVEVSLRLTAN
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCHHHHEEEEEEEEEC
QTKIFNVTTDLLLPSPVVMGDAQQLHQVLINLIQNACHAIRQDAECYECKEHINIQTCVE
CEEEEEEEHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEC
DKHICLVISDKGAGMDSATLQRITEPFFTTRRSSGGTGLGLSVCSRIIKEHKADMQITSR
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHH
LGKGTVIKIRFPLEY
CCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1333793 [H]