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The map label for this gene is infC [H]

Identifier: 157825815

GI number: 157825815

Start: 673288

End: 673731

Strand: Direct

Name: infC [H]

Synonym: A1C_03750

Alternate gene names: 157825815

Gene position: 673288-673731 (Clockwise)

Preceding gene: 157825814

Following gene: 157825816

Centisome position: 54.69

GC content: 34.23

Gene sequence:

>444_bases
ATGCACGGCGTCGTAAATATTAGGGAAGCATTAGATATGGCCGAAAGAGTCGGTCTTGACTTAGTCGAGATATCACCAAA
TGCTGTACCCCCTGTCTGTAAAATTCTAGATTTTGGTAAATTTAAGTACGAAAGCAAAAAGCGTTTACATGAAGCACGCA
AAAAGCAAAAAGTCGTCGTACTTAAAGAAATGAAATTTAAACCTAATATCAGTATAGGTGATTTTGAAACTAAGCTAAGA
AAAATAAAAGAATTTTTAAAAGACGGAGATAAAGTAAAAATTTCTTTATGGTTTAAGGGACGAGAAATTCTTCATAAAGA
AGTTGGTCAAGAACTATTTAAACGTATAGAAGTAGGACTCGAAGGACTCGTTAAAATCGATCAGCATGCTAAAATGGAAG
GTAAGCAGATGATAATGATAGTTAGCCCTGATATTAAGGTGTGA

Upstream 100 bases:

>100_bases
AAACATAATACGGAGCAACTTTATTTCTAAAAATAATTTTCCTAAGGCTAATAGAGAAATCAGAGCTAGAGAAGTTCGTC
TAGTAGGCGAAAACGGCGAA

Downstream 100 bases:

>100_bases
TAGCTACTCAAATCATTATGAGCTACGTGGCTGTTGTTACATGGATCGGTAGAACCTACTCGATTTTGTTCTCGCGTAGG
CGTGGATCCAGCAAAATAAC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MHGVVNIREALDMAERVGLDLVEISPNAVPPVCKILDFGKFKYESKKRLHEARKKQKVVVLKEMKFKPNISIGDFETKLR
KIKEFLKDGDKVKISLWFKGREILHKEVGQELFKRIEVGLEGLVKIDQHAKMEGKQMIMIVSPDIKV

Sequences:

>Translated_147_residues
MHGVVNIREALDMAERVGLDLVEISPNAVPPVCKILDFGKFKYESKKRLHEARKKQKVVVLKEMKFKPNISIGDFETKLR
KIKEFLKDGDKVKISLWFKGREILHKEVGQELFKRIEVGLEGLVKIDQHAKMEGKQMIMIVSPDIKV
>Mature_147_residues
MHGVVNIREALDMAERVGLDLVEISPNAVPPVCKILDFGKFKYESKKRLHEARKKQKVVVLKEMKFKPNISIGDFETKLR
KIKEFLKDGDKVKISLWFKGREILHKEVGQELFKRIEVGLEGLVKIDQHAKMEGKQMIMIVSPDIKV

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=142, Percent_Identity=50.7042253521127, Blast_Score=140, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 16967; Mature: 16967

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGVVNIREALDMAERVGLDLVEISPNAVPPVCKILDFGKFKYESKKRLHEARKKQKVVV
CCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHEEE
LKEMKFKPNISIGDFETKLRKIKEFLKDGDKVKISLWFKGREILHKEVGQELFKRIEVGL
EECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHH
EGLVKIDQHAKMEGKQMIMIVSPDIKV
HHHHHHHHHCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MHGVVNIREALDMAERVGLDLVEISPNAVPPVCKILDFGKFKYESKKRLHEARKKQKVVV
CCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHEEE
LKEMKFKPNISIGDFETKLRKIKEFLKDGDKVKISLWFKGREILHKEVGQELFKRIEVGL
EECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHH
EGLVKIDQHAKMEGKQMIMIVSPDIKV
HHHHHHHHHCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]