Click here to switch to the map view.

The map label for this gene is sucC [H]

Identifier: 157825718

GI number: 157825718

Start: 586842

End: 588002

Strand: Reverse

Name: sucC [H]

Synonym: A1C_03220

Alternate gene names: 157825718

Gene position: 588002-586842 (Counterclockwise)

Preceding gene: 157825719

Following gene: 157825717

Centisome position: 47.76

GC content: 37.21

Gene sequence:

>1161_bases
ATGAATATTCATGAATATCAAGCAAAAGAGATTTTGAGAAAATACGGCGTACCTACTTCCACTGGACTCGTTGTTACGAA
AACCGAGAAGATTAACGAAACCATAGATAAGTTAAATACAGAAGTATATGTGGTTAAAGCACAAATACATGCCGGCGGTA
GAGGTAAAGCAGGCGGTGTTAAGGTTGTTAAGAGTAAAGAAGAAGCAAAAAAAGTGGCTCATGACATGTTTGGTATTAAT
TTAGTAACACATCAAACAGAACCTCAAGGACAAAAAGTAAATTGTCTTTATATCGAATCAGGTTGTGATATCTTAAAAGA
ATATTATTTCAGTATAGTATTTGATAGATCGGCAAGTTGTATTACTTTCATAGCTTCTACCGAAGGAGGAGTCGATATTG
AAGAAGTAGCAGCAAAAACTCCTGCAAAAATTATTAAATTTTCTGTTGATCCTGCAACCGGTTTACAAGATTTTCATATG
CGTGGTATAGCTTATGAGCTAGGTTTTAAGGATAACCAAGCTAAACAAATGAAAGAAATAGTAAAATCAGTGTATAATGC
TTTTGTTGAAACTGATGCTGCACAAATTGAAATCAACCCGTTAATTGTACAAACGGACGGAAATTTACTCGCTTTAGACG
CAAAAATCACTTTTGATGATAACGGCTTATTCAAACATCCAAATATTACGGCAATGCGTGATCACGATGAGGAAGATCCT
TTAGAAACTAGAGCGGCAAATGCGGGGCTTAGCTATGTAAAAATGGGCGGTAATATCGGTTGTATGGTTAACGGTGCGGG
TCTTGCTATGGCTACTATGGATATTATTAAGCTTTACGGTGCGTCACCTGCAAATTTCTTAGATGTTGGCGGCGGGGCTG
ATCGTGAGCGTGTAAAAGAAGCTTTAAAAATAATTTTATCCGATAAAGAAGTGCAAGGGATCTTAGTTAATATTTTCGGC
GGTATTATGCGTTGTGATATTATAGCGGAAGGGATTATTGCAGCTGCAAAAGACATAGGTATAAAAGTGCCATTAGTCGT
CCGTTTAGCCGGTACTAACGTTGAAAAAGGCGAAGAAATTTTATCAAATTCCGGTTTAGACATAATACCGGCACATGATT
TAGCAGATGCAGCAAATAAGATAGTCGCGGCTATTAGGTAG

Upstream 100 bases:

>100_bases
GATTTCAGCCTACGCGGGACTGACATCATAAACTCTCTACTTTACAGTTTAAAGATTAATTATTATACTGTGCTTTAATT
ATTTAAATACATTATTTAAA

Downstream 100 bases:

>100_bases
GTGTACTCGTCATGAGCTAGGCAAGCGTAGTACTTACGTGGCTTTTATGGCATTCACGCGTATGCTGGGAATTACATAAT
AATGATCCATACAACAACGC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MNIHEYQAKEILRKYGVPTSTGLVVTKTEKINETIDKLNTEVYVVKAQIHAGGRGKAGGVKVVKSKEEAKKVAHDMFGIN
LVTHQTEPQGQKVNCLYIESGCDILKEYYFSIVFDRSASCITFIASTEGGVDIEEVAAKTPAKIIKFSVDPATGLQDFHM
RGIAYELGFKDNQAKQMKEIVKSVYNAFVETDAAQIEINPLIVQTDGNLLALDAKITFDDNGLFKHPNITAMRDHDEEDP
LETRAANAGLSYVKMGGNIGCMVNGAGLAMATMDIIKLYGASPANFLDVGGGADRERVKEALKIILSDKEVQGILVNIFG
GIMRCDIIAEGIIAAAKDIGIKVPLVVRLAGTNVEKGEEILSNSGLDIIPAHDLADAANKIVAAIR

Sequences:

>Translated_386_residues
MNIHEYQAKEILRKYGVPTSTGLVVTKTEKINETIDKLNTEVYVVKAQIHAGGRGKAGGVKVVKSKEEAKKVAHDMFGIN
LVTHQTEPQGQKVNCLYIESGCDILKEYYFSIVFDRSASCITFIASTEGGVDIEEVAAKTPAKIIKFSVDPATGLQDFHM
RGIAYELGFKDNQAKQMKEIVKSVYNAFVETDAAQIEINPLIVQTDGNLLALDAKITFDDNGLFKHPNITAMRDHDEEDP
LETRAANAGLSYVKMGGNIGCMVNGAGLAMATMDIIKLYGASPANFLDVGGGADRERVKEALKIILSDKEVQGILVNIFG
GIMRCDIIAEGIIAAAKDIGIKVPLVVRLAGTNVEKGEEILSNSGLDIIPAHDLADAANKIVAAIR
>Mature_386_residues
MNIHEYQAKEILRKYGVPTSTGLVVTKTEKINETIDKLNTEVYVVKAQIHAGGRGKAGGVKVVKSKEEAKKVAHDMFGIN
LVTHQTEPQGQKVNCLYIESGCDILKEYYFSIVFDRSASCITFIASTEGGVDIEEVAAKTPAKIIKFSVDPATGLQDFHM
RGIAYELGFKDNQAKQMKEIVKSVYNAFVETDAAQIEINPLIVQTDGNLLALDAKITFDDNGLFKHPNITAMRDHDEEDP
LETRAANAGLSYVKMGGNIGCMVNGAGLAMATMDIIKLYGASPANFLDVGGGADRERVKEALKIILSDKEVQGILVNIFG
GIMRCDIIAEGIIAAAKDIGIKVPLVVRLAGTNVEKGEEILSNSGLDIIPAHDLADAANKIVAAIR

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=389, Percent_Identity=45.5012853470437, Blast_Score=334, Evalue=8e-92,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=44.3864229765013, Blast_Score=319, Evalue=3e-87,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=43.801652892562, Blast_Score=298, Evalue=6e-81,
Organism=Escherichia coli, GI1786948, Length=385, Percent_Identity=52.2077922077922, Blast_Score=397, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17567829, Length=388, Percent_Identity=44.5876288659794, Blast_Score=327, Evalue=7e-90,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=42.3857868020305, Blast_Score=318, Evalue=3e-87,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=44.3877551020408, Blast_Score=332, Evalue=7e-92,
Organism=Drosophila melanogaster, GI21356231, Length=393, Percent_Identity=46.0559796437659, Blast_Score=327, Evalue=1e-89,
Organism=Drosophila melanogaster, GI161078106, Length=386, Percent_Identity=44.559585492228, Blast_Score=314, Evalue=7e-86,
Organism=Drosophila melanogaster, GI24645208, Length=386, Percent_Identity=44.559585492228, Blast_Score=314, Evalue=7e-86,
Organism=Drosophila melanogaster, GI281361397, Length=387, Percent_Identity=44.702842377261, Blast_Score=312, Evalue=2e-85,
Organism=Drosophila melanogaster, GI281361395, Length=387, Percent_Identity=44.702842377261, Blast_Score=312, Evalue=2e-85,
Organism=Drosophila melanogaster, GI281363477, Length=413, Percent_Identity=27.6029055690073, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281363475, Length=413, Percent_Identity=27.6029055690073, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281363473, Length=413, Percent_Identity=27.6029055690073, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41665; Mature: 41665

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKEILRKYGVPTSTGLVVTKTEKINETIDKLNTEVYVVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
KVVKSKEEAKKVAHDMFGINLVTHQTEPQGQKVNCLYIESGCDILKEYYFSIVFDRSASC
EEEECHHHHHHHHHHHHCEEEEEECCCCCCCEEEEEEEECCHHHHHHHHHEEEECCCCCE
ITFIASTEGGVDIEEVAAKTPAKIIKFSVDPATGLQDFHMRGIAYELGFKDNQAKQMKEI
EEEEEECCCCCCHHHHHHCCCCEEEEEECCCCCCCHHHHHCCEEEEECCCCCHHHHHHHH
VKSVYNAFVETDAAQIEINPLIVQTDGNLLALDAKITFDDNGLFKHPNITAMRDHDEEDP
HHHHHHHHHCCCCCEEEEEEEEEEECCCEEEEEEEEEECCCCEEECCCEEEECCCCCCCC
LETRAANAGLSYVKMGGNIGCMVNGAGLAMATMDIIKLYGASPANFLDVGGGADRERVKE
HHHHHHCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
ALKIILSDKEVQGILVNIFGGIMRCDIIAEGIIAAAKDIGIKVPLVVRLAGTNVEKGEEI
HHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCEECEEEEEEECCCCHHHHHH
LSNSGLDIIPAHDLADAANKIVAAIR
HHCCCCEEEECHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKEILRKYGVPTSTGLVVTKTEKINETIDKLNTEVYVVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
KVVKSKEEAKKVAHDMFGINLVTHQTEPQGQKVNCLYIESGCDILKEYYFSIVFDRSASC
EEEECHHHHHHHHHHHHCEEEEEECCCCCCCEEEEEEEECCHHHHHHHHHEEEECCCCCE
ITFIASTEGGVDIEEVAAKTPAKIIKFSVDPATGLQDFHMRGIAYELGFKDNQAKQMKEI
EEEEEECCCCCCHHHHHHCCCCEEEEEECCCCCCCHHHHHCCEEEEECCCCCHHHHHHHH
VKSVYNAFVETDAAQIEINPLIVQTDGNLLALDAKITFDDNGLFKHPNITAMRDHDEEDP
HHHHHHHHHCCCCCEEEEEEEEEEECCCEEEEEEEEEECCCCEEECCCEEEECCCCCCCC
LETRAANAGLSYVKMGGNIGCMVNGAGLAMATMDIIKLYGASPANFLDVGGGADRERVKE
HHHHHHCCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
ALKIILSDKEVQGILVNIFGGIMRCDIIAEGIIAAAKDIGIKVPLVVRLAGTNVEKGEEI
HHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCEECEEEEEEECCCCHHHHHH
LSNSGLDIIPAHDLADAANKIVAAIR
HHCCCCEEEECHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA