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The map label for this gene is sucD [H]

Identifier: 157825717

GI number: 157825717

Start: 585801

End: 586679

Strand: Reverse

Name: sucD [H]

Synonym: A1C_03215

Alternate gene names: 157825717

Gene position: 586679-585801 (Counterclockwise)

Preceding gene: 157825718

Following gene: 157825712

Centisome position: 47.66

GC content: 40.16

Gene sequence:

>879_bases
ATGGCAATATTAATAAATAAAAAAACAAAGGTTATCTGTCAGGGTTTTACTGGTTCACAAGGAACTTTTCACTCTGAACA
AGCGATAGCTTACGGCACTAACATGGTTGGCGGTATTACACCGGGCAAAGGCGGTCATACTCACCTTGATTTACCTGTAT
ATAATACCGTACATGAAGCAAAAGCAAAAACTGGTGCAAATGCAAGCGTCATATATGTTCCGCCCAGCTTTGCCGCTGAT
TCGATCTTAGAAGCAATCGATGCAAAAATTGAAGTAGTAGTATGTATAACGGAAGGAATTCCGATACTTGATATGGTGAA
AGTAAAACGTGCTTTAGTCGGTTCTAAAACTAGATTAATCGGGCCTAACTGCCCTGGAGTTATCACACCTGGTGAATGTA
AAATCGGTATTATGCCTGGGCATATTCATAAAAGAGGAACGATAGGTATTGTTTCAAGATCAGGTACTCTAACTTATGAA
GCAGTAGCACAGACAACAGCCGTAGGACTTGGACAATCTACATGTGTCGGTATAGGCGGCGATCCTGTTAACGGCACTAA
TTTCGTTGATTGTATTGATATGTTCTTAAAAGATGATGAAACAAAAGCAATTATTATGATTGGTGAAATTGGCGGTAATG
CAGAAGAAGATGCAGCCGAGTTTATCAAGCAATCAAAAATCAAGAAGCCTATTGTTAGCTTTATTGCAGGTATTACAGCA
CCTCCCGGTAAAAGAATGGGACATGCCGGAGCTATTATTGCCGGAGGACAAGGAAGTGCCGAAGATAAGCTTGAAGTTCT
ACAAAGTGCCGGCGTAACTATCACTAAATCCCCTGCCGATATCGGTAAAACTATGTTTGATTTGTTAAATAAAGGCTAA

Upstream 100 bases:

>100_bases
TGCTGGGAATTACATAATAATGATCCATACAACAACGCCTTCAGTTGCTTGCAATGACGGTGACAATTACACAAAATAAA
AACAATAAAAATTATTTAAC

Downstream 100 bases:

>100_bases
AATTATTCAACAGCAATCGATGAATCGATGTCATTCCTAGCTAAAAGCAGGAATCTAGAAAAGTAATTTTAATATTTCCA
CGTGCGTGGGAAGGGATTGT

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MAILINKKTKVICQGFTGSQGTFHSEQAIAYGTNMVGGITPGKGGHTHLDLPVYNTVHEAKAKTGANASVIYVPPSFAAD
SILEAIDAKIEVVVCITEGIPILDMVKVKRALVGSKTRLIGPNCPGVITPGECKIGIMPGHIHKRGTIGIVSRSGTLTYE
AVAQTTAVGLGQSTCVGIGGDPVNGTNFVDCIDMFLKDDETKAIIMIGEIGGNAEEDAAEFIKQSKIKKPIVSFIAGITA
PPGKRMGHAGAIIAGGQGSAEDKLEVLQSAGVTITKSPADIGKTMFDLLNKG

Sequences:

>Translated_292_residues
MAILINKKTKVICQGFTGSQGTFHSEQAIAYGTNMVGGITPGKGGHTHLDLPVYNTVHEAKAKTGANASVIYVPPSFAAD
SILEAIDAKIEVVVCITEGIPILDMVKVKRALVGSKTRLIGPNCPGVITPGECKIGIMPGHIHKRGTIGIVSRSGTLTYE
AVAQTTAVGLGQSTCVGIGGDPVNGTNFVDCIDMFLKDDETKAIIMIGEIGGNAEEDAAEFIKQSKIKKPIVSFIAGITA
PPGKRMGHAGAIIAGGQGSAEDKLEVLQSAGVTITKSPADIGKTMFDLLNKG
>Mature_291_residues
AILINKKTKVICQGFTGSQGTFHSEQAIAYGTNMVGGITPGKGGHTHLDLPVYNTVHEAKAKTGANASVIYVPPSFAADS
ILEAIDAKIEVVVCITEGIPILDMVKVKRALVGSKTRLIGPNCPGVITPGECKIGIMPGHIHKRGTIGIVSRSGTLTYEA
VAQTTAVGLGQSTCVGIGGDPVNGTNFVDCIDMFLKDDETKAIIMIGEIGGNAEEDAAEFIKQSKIKKPIVSFIAGITAP
PGKRMGHAGAIIAGGQGSAEDKLEVLQSAGVTITKSPADIGKTMFDLLNKG

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=293, Percent_Identity=70.3071672354949, Blast_Score=365, Evalue=1e-101,
Organism=Homo sapiens, GI38569423, Length=252, Percent_Identity=29.3650793650794, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI38569421, Length=252, Percent_Identity=29.3650793650794, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1786949, Length=290, Percent_Identity=69.6551724137931, Blast_Score=407, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17553126, Length=291, Percent_Identity=65.6357388316151, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17550194, Length=285, Percent_Identity=65.9649122807018, Blast_Score=366, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17557344, Length=255, Percent_Identity=30.9803921568627, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17551266, Length=255, Percent_Identity=29.4117647058824, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324716, Length=297, Percent_Identity=51.1784511784512, Blast_Score=291, Evalue=1e-79,
Organism=Drosophila melanogaster, GI21356559, Length=287, Percent_Identity=59.581881533101, Blast_Score=355, Evalue=2e-98,
Organism=Drosophila melanogaster, GI28574296, Length=291, Percent_Identity=64.9484536082474, Blast_Score=353, Evalue=8e-98,
Organism=Drosophila melanogaster, GI281363477, Length=256, Percent_Identity=29.6875, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281363475, Length=256, Percent_Identity=29.6875, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281363473, Length=256, Percent_Identity=29.6875, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30222; Mature: 30091

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILINKKTKVICQGFTGSQGTFHSEQAIAYGTNMVGGITPGKGGHTHLDLPVYNTVHEA
CEEEEECCCEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCHHHHHHHH
KAKTGANASVIYVPPSFAADSILEAIDAKIEVVVCITEGIPILDMVKVKRALVGSKTRLI
HHCCCCCCEEEEECCCCCHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEE
GPNCPGVITPGECKIGIMPGHIHKRGTIGIVSRSGTLTYEAVAQTTAVGLGQSTCVGIGG
CCCCCCEECCCCEEEEEECCCCCCCCEEEEEECCCCEEHHHHHHHHHHCCCCCEEEECCC
DPVNGTNFVDCIDMFLKDDETKAIIMIGEIGGNAEEDAAEFIKQSKIKKPIVSFIAGITA
CCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PPGKRMGHAGAIIAGGQGSAEDKLEVLQSAGVTITKSPADIGKTMFDLLNKG
CCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AILINKKTKVICQGFTGSQGTFHSEQAIAYGTNMVGGITPGKGGHTHLDLPVYNTVHEA
EEEEECCCEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCHHHHHHHH
KAKTGANASVIYVPPSFAADSILEAIDAKIEVVVCITEGIPILDMVKVKRALVGSKTRLI
HHCCCCCCEEEEECCCCCHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEE
GPNCPGVITPGECKIGIMPGHIHKRGTIGIVSRSGTLTYEAVAQTTAVGLGQSTCVGIGG
CCCCCCEECCCCEEEEEECCCCCCCCEEEEEECCCCEEHHHHHHHHHHCCCCCEEEECCC
DPVNGTNFVDCIDMFLKDDETKAIIMIGEIGGNAEEDAAEFIKQSKIKKPIVSFIAGITA
CCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PPGKRMGHAGAIIAGGQGSAEDKLEVLQSAGVTITKSPADIGKTMFDLLNKG
CCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]