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The map label for this gene is lspA [H]

Identifier: 157825686

GI number: 157825686

Start: 552987

End: 553577

Strand: Direct

Name: lspA [H]

Synonym: A1C_03040

Alternate gene names: 157825686

Gene position: 552987-553577 (Clockwise)

Preceding gene: 157825685

Following gene: 157825687

Centisome position: 44.92

GC content: 30.63

Gene sequence:

>591_bases
ATGTGCCTACTCATAAAAAAACTATATCTAACATTTGCTCGTAGTACTAGTATAATAATCACCTTAGTAATTATTGATCA
GTTAAGTAAATGGTGGTTTATTGATAATTTGAGATGGACACCAGGCTTAATGCTCAAGGTTACTTCTTTCTTAAATATGG
TTTATACTTGGAATTACGGTATTAGTTTTGGTCTAATGCGTGAATATTATCAGTATAGTAATGCTATTTTTTTAATAACG
AACACGCTTATTGTCTGTTATTTATATTATTTGATGATACGTTCAAACACAATAGGGAGTTTTGCCGGTTATAGTTTTGT
CATTGGTGGGGCTGTTGGTAATCTAATTGATAGGTGTTTTAGAGGGGCAGTCTTTGACTTCATTCATTTCCATTATCATA
ATTATAGCTTCCCCGTATTTAATTTAGCTGATTGCTTTATTACAATAGGAGTAATTATCTTAATAGAAGATTATGATAAT
ACTAAAAAAGTTATTGAAGAAAAGATTAAAGGGAATTATGATAATGCTCAAATTGAAGCTATGGCTGAAAAAATTCGTAA
CACCGATCAGGGCGGTAACGATAAAGTATAA

Upstream 100 bases:

>100_bases
GGTATGACACCGAATGGATTTTTTGGTCCACGTAACAATGCCTACTCGCAATGACGATTTGCGTAACCAGTCCCATGCAT
TTAATTTTTCATAAACATCT

Downstream 100 bases:

>100_bases
TTTAAATTAAAGGTGTTTAAGTGAAAAAGATTTTTTTATTATTGACTGTTTTATTAATTACTTCTGCTTGTAGTAAAAAG
TTAAAAGAAACCTTAGGTAT

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MCLLIKKLYLTFARSTSIIITLVIIDQLSKWWFIDNLRWTPGLMLKVTSFLNMVYTWNYGISFGLMREYYQYSNAIFLIT
NTLIVCYLYYLMIRSNTIGSFAGYSFVIGGAVGNLIDRCFRGAVFDFIHFHYHNYSFPVFNLADCFITIGVIILIEDYDN
TKKVIEEKIKGNYDNAQIEAMAEKIRNTDQGGNDKV

Sequences:

>Translated_196_residues
MCLLIKKLYLTFARSTSIIITLVIIDQLSKWWFIDNLRWTPGLMLKVTSFLNMVYTWNYGISFGLMREYYQYSNAIFLIT
NTLIVCYLYYLMIRSNTIGSFAGYSFVIGGAVGNLIDRCFRGAVFDFIHFHYHNYSFPVFNLADCFITIGVIILIEDYDN
TKKVIEEKIKGNYDNAQIEAMAEKIRNTDQGGNDKV
>Mature_196_residues
MCLLIKKLYLTFARSTSIIITLVIIDQLSKWWFIDNLRWTPGLMLKVTSFLNMVYTWNYGISFGLMREYYQYSNAIFLIT
NTLIVCYLYYLMIRSNTIGSFAGYSFVIGGAVGNLIDRCFRGAVFDFIHFHYHNYSFPVFNLADCFITIGVIILIEDYDN
TKKVIEEKIKGNYDNAQIEAMAEKIRNTDQGGNDKV

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=149, Percent_Identity=30.2013422818792, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 22746; Mature: 22746

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCLLIKKLYLTFARSTSIIITLVIIDQLSKWWFIDNLRWTPGLMLKVTSFLNMVYTWNYG
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHEECCC
ISFGLMREYYQYSNAIFLITNTLIVCYLYYLMIRSNTIGSFAGYSFVIGGAVGNLIDRCF
CHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RGAVFDFIHFHYHNYSFPVFNLADCFITIGVIILIEDYDNTKKVIEEKIKGNYDNAQIEA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHCCCCCCHHHHH
MAEKIRNTDQGGNDKV
HHHHHHCCCCCCCCCC
>Mature Secondary Structure
MCLLIKKLYLTFARSTSIIITLVIIDQLSKWWFIDNLRWTPGLMLKVTSFLNMVYTWNYG
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHEECCC
ISFGLMREYYQYSNAIFLITNTLIVCYLYYLMIRSNTIGSFAGYSFVIGGAVGNLIDRCF
CHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RGAVFDFIHFHYHNYSFPVFNLADCFITIGVIILIEDYDNTKKVIEEKIKGNYDNAQIEA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHCCCCCCHHHHH
MAEKIRNTDQGGNDKV
HHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA