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The map label for this gene is slt [H]

Identifier: 157825675

GI number: 157825675

Start: 538373

End: 540370

Strand: Direct

Name: slt [H]

Synonym: A1C_02985

Alternate gene names: 157825675

Gene position: 538373-540370 (Clockwise)

Preceding gene: 157825674

Following gene: 157825676

Centisome position: 43.73

GC content: 32.48

Gene sequence:

>1998_bases
ATGAAAATCACAATAAAATTATTAACTTCTATATTTTTGTTAGCTTTGAACTGGATCCCGTGGTCAAGCTACGGGATGAC
AACTGGGGTAAATTCTGATTATGTAGATAATGTTAAGCAAGTTTTTACACATATCGATCAAAAAAATTGGTCACAAGCTG
AAGATTTAGCTCTAGAGGTAAATAATAAAGTTTTAACAAAAATTGTACTTTCTCAGAAATATTTAGATAATAAATATTCA
GATAATAGTTTTGAACATGTAATAAGATTTTTACGCAATAACCCGGATTGGCCTCAAAACAAGCGGCTTGAAGAAAGAGC
GGAAGAATATCTAAATAATAATACAAATAAAAAAGTCATTTTTGATTGGTTTAGTAAACATCCTCCTGTTACAGGCAAAG
GTTATAAATTTTATGCGGCAGCTGCAAGTAGTTTAATCAAAGATCAGAAGATATTGCTACCTATTATTAAAGAGGCTTGG
GTGTATGCCAATTTCACTCCTGAAGAAGAAAGTGTATATTACAATAAGTGGCATAAATATTTAACTGCAAATGATCATTT
AGAGCGGATAGAAGAGCATTTATGGCAACATGATATTAGGTCTGCCGAGCAATCCCTAAAATATGTAGATCAAGGTTATC
GTGATTCTTTTAAAGCACAAATTGCGATTATAGGTAAATTACCAAATGCTGAAAAGCTTTTTAAAAATGTTCCTGAAAAA
TACTATACTTCCGGTTTGTTATATCGTTATTTAGATTCTAGAAAGACGCAAAAACCGACAAGTGGAGATATTTCTTTATT
TAAGAAAGCTAAAAATAACCGTAAACATTTTGCAAAATGGTGTCGCATTCAGTCCTATTATGCTCGTGAATTCATCGATT
ACAAAGATTTTTCAAATAGTTATAGAATTGCAACGATGCCCTTTGCGACTTGTCCTGAAACTATAAGAGAGCAGGAATGG
CTTGCGGGTTGGCTTTCTTTAAGCTTTTTAAAAAAGCCTGATCAAGCATTAGTACATTTTAATAAGTTTATTAAAGTTGT
TAAAACCCCGATTAGTTTAGCACGTGGATTTTATTGGCTCGGTCGTACTTATGAAGCAAAAGGCTATAAGCAAACGGCTA
GAAAATTTTACGAGCAGGCAGCCAAATATTCTTTTACCTTTTACGGACAGGTAGCACATGTTGAATTAAATAGAACAAAA
TTAGTTTTACCTCCTATTCCTGTAATAACTTCTGAAGCAAGGAAAAATATCGAGAATAAAGAGATTATCAAAGCAATAAG
GTTACTGGTTAAATATAATAAGCATAATTTAGCCATGATATATTCCAAAGCAGCTATTAAAAACACTAAAAATCCTGCAG
AAATTCAAATAATTGCGAATATTATTAAAGCAAATAATAATACTAACCATATGGTTGAGGTGGCAAAAATTGCTGCCCAA
AATCATGCTTTTATTCCAGATTGTGCTTTTCCAACGCCTTATAATCTAGGAGGTTTGCCTATCCCACCTCATTTAACTTA
TGGAATAATTAGACAAGAATCGGTCTTTGACCATAGGGCCGTGAGTTATGCAAATGCCATGGGGCTGATGCAGCTTATTA
AGGGGGCTGCTTGTGATACCGCAAAATCTATAAATATGAAATGTAATATAGCAGATTTAACTAGGAATCCTGTATATAAT
ATCAAGCTTGGTTCGCATTATTTCAAAAAATTATTAGATGATCATAAAGGTTCGTATATTCTGTCTATCGCCTCTTATAA
TGCAGGGAGTCATAATGTAGTAAAATGGATCGATAGATTCGGTGATCCAAGGGATATTAAAGATATAAGAAAGGTTGTTG
ACTGGATAGAACTTATACCTTATCGAGAAACAAGAGATTACGTTCAAAGAGTACTTGAAAATATTCAGATTTATAGGGTA
ATCTTAAATAAGAATAATAACTTGTACTTTAAGCGTGACTTGCATGCTTGCGATATAACAAAAATTAATTTTTATTAG

Upstream 100 bases:

>100_bases
TCTATAAATTAGAATTTTTAACTGGATTGCTTCGTCGAATTACTACGTAATTCTTCTCGCAATGGCTACTCCAGTATCCA
TGCAACAAATCACACAACTT

Downstream 100 bases:

>100_bases
TGTTTTGTTTTGAAATAATATATTATAGATACAAATATGATCTGGAAACTAATTAACAGTATGCATTAAGGAGGAGAATA
TGAAAAAGTTCGAGCAACAC

Product: soluble lytic murein transglycosylase precursor

Products: 1,6-Anhydrobond [C]

Alternate protein names: Peptidoglycan lytic exotransglycosylase [H]

Number of amino acids: Translated: 665; Mature: 665

Protein sequence:

>665_residues
MKITIKLLTSIFLLALNWIPWSSYGMTTGVNSDYVDNVKQVFTHIDQKNWSQAEDLALEVNNKVLTKIVLSQKYLDNKYS
DNSFEHVIRFLRNNPDWPQNKRLEERAEEYLNNNTNKKVIFDWFSKHPPVTGKGYKFYAAAASSLIKDQKILLPIIKEAW
VYANFTPEEESVYYNKWHKYLTANDHLERIEEHLWQHDIRSAEQSLKYVDQGYRDSFKAQIAIIGKLPNAEKLFKNVPEK
YYTSGLLYRYLDSRKTQKPTSGDISLFKKAKNNRKHFAKWCRIQSYYAREFIDYKDFSNSYRIATMPFATCPETIREQEW
LAGWLSLSFLKKPDQALVHFNKFIKVVKTPISLARGFYWLGRTYEAKGYKQTARKFYEQAAKYSFTFYGQVAHVELNRTK
LVLPPIPVITSEARKNIENKEIIKAIRLLVKYNKHNLAMIYSKAAIKNTKNPAEIQIIANIIKANNNTNHMVEVAKIAAQ
NHAFIPDCAFPTPYNLGGLPIPPHLTYGIIRQESVFDHRAVSYANAMGLMQLIKGAACDTAKSINMKCNIADLTRNPVYN
IKLGSHYFKKLLDDHKGSYILSIASYNAGSHNVVKWIDRFGDPRDIKDIRKVVDWIELIPYRETRDYVQRVLENIQIYRV
ILNKNNNLYFKRDLHACDITKINFY

Sequences:

>Translated_665_residues
MKITIKLLTSIFLLALNWIPWSSYGMTTGVNSDYVDNVKQVFTHIDQKNWSQAEDLALEVNNKVLTKIVLSQKYLDNKYS
DNSFEHVIRFLRNNPDWPQNKRLEERAEEYLNNNTNKKVIFDWFSKHPPVTGKGYKFYAAAASSLIKDQKILLPIIKEAW
VYANFTPEEESVYYNKWHKYLTANDHLERIEEHLWQHDIRSAEQSLKYVDQGYRDSFKAQIAIIGKLPNAEKLFKNVPEK
YYTSGLLYRYLDSRKTQKPTSGDISLFKKAKNNRKHFAKWCRIQSYYAREFIDYKDFSNSYRIATMPFATCPETIREQEW
LAGWLSLSFLKKPDQALVHFNKFIKVVKTPISLARGFYWLGRTYEAKGYKQTARKFYEQAAKYSFTFYGQVAHVELNRTK
LVLPPIPVITSEARKNIENKEIIKAIRLLVKYNKHNLAMIYSKAAIKNTKNPAEIQIIANIIKANNNTNHMVEVAKIAAQ
NHAFIPDCAFPTPYNLGGLPIPPHLTYGIIRQESVFDHRAVSYANAMGLMQLIKGAACDTAKSINMKCNIADLTRNPVYN
IKLGSHYFKKLLDDHKGSYILSIASYNAGSHNVVKWIDRFGDPRDIKDIRKVVDWIELIPYRETRDYVQRVLENIQIYRV
ILNKNNNLYFKRDLHACDITKINFY
>Mature_665_residues
MKITIKLLTSIFLLALNWIPWSSYGMTTGVNSDYVDNVKQVFTHIDQKNWSQAEDLALEVNNKVLTKIVLSQKYLDNKYS
DNSFEHVIRFLRNNPDWPQNKRLEERAEEYLNNNTNKKVIFDWFSKHPPVTGKGYKFYAAAASSLIKDQKILLPIIKEAW
VYANFTPEEESVYYNKWHKYLTANDHLERIEEHLWQHDIRSAEQSLKYVDQGYRDSFKAQIAIIGKLPNAEKLFKNVPEK
YYTSGLLYRYLDSRKTQKPTSGDISLFKKAKNNRKHFAKWCRIQSYYAREFIDYKDFSNSYRIATMPFATCPETIREQEW
LAGWLSLSFLKKPDQALVHFNKFIKVVKTPISLARGFYWLGRTYEAKGYKQTARKFYEQAAKYSFTFYGQVAHVELNRTK
LVLPPIPVITSEARKNIENKEIIKAIRLLVKYNKHNLAMIYSKAAIKNTKNPAEIQIIANIIKANNNTNHMVEVAKIAAQ
NHAFIPDCAFPTPYNLGGLPIPPHLTYGIIRQESVFDHRAVSYANAMGLMQLIKGAACDTAKSINMKCNIADLTRNPVYN
IKLGSHYFKKLLDDHKGSYILSIASYNAGSHNVVKWIDRFGDPRDIKDIRKVVDWIELIPYRETRDYVQRVLENIQIYRV
ILNKNNNLYFKRDLHACDITKINFY

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI87082441, Length=167, Percent_Identity=32.3353293413174, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011989
- InterPro:   IPR016026
- InterPro:   IPR008258
- InterPro:   IPR012289
- InterPro:   IPR008939
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 77584; Mature: 77584

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS00037 MYB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITIKLLTSIFLLALNWIPWSSYGMTTGVNSDYVDNVKQVFTHIDQKNWSQAEDLALEV
CEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHC
NNKVLTKIVLSQKYLDNKYSDNSFEHVIRFLRNNPDWPQNKRLEERAEEYLNNNTNKKVI
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEE
FDWFSKHPPVTGKGYKFYAAAASSLIKDQKILLPIIKEAWVYANFTPEEESVYYNKWHKY
EEEHHCCCCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHCEEEECCCCCCCCHHHHHHHHH
LTANDHLERIEEHLWQHDIRSAEQSLKYVDQGYRDSFKAQIAIIGKLPNAEKLFKNVPEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHCCHH
YYTSGLLYRYLDSRKTQKPTSGDISLFKKAKNNRKHFAKWCRIQSYYAREFIDYKDFSNS
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
YRIATMPFATCPETIREQEWLAGWLSLSFLKKPDQALVHFNKFIKVVKTPISLARGFYWL
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
GRTYEAKGYKQTARKFYEQAAKYSFTFYGQVAHVELNRTKLVLPPIPVITSEARKNIENK
CCEECCCCHHHHHHHHHHHHHHCEEEEEEEEEEEEECCEEEEECCCCCEECHHHCCCCHH
EIIKAIRLLVKYNKHNLAMIYSKAAIKNTKNPAEIQIIANIIKANNNTNHMVEVAKIAAQ
HHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHC
NHAFIPDCAFPTPYNLGGLPIPPHLTYGIIRQESVFDHRAVSYANAMGLMQLIKGAACDT
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AKSINMKCNIADLTRNPVYNIKLGSHYFKKLLDDHKGSYILSIASYNAGSHNVVKWIDRF
CCCCCEEEEEEECCCCCEEEEEECHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHC
GDPRDIKDIRKVVDWIELIPYRETRDYVQRVLENIQIYRVILNKNNNLYFKRDLHACDIT
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEEEEECCCCEEEEECCCEECEE
KINFY
EEECC
>Mature Secondary Structure
MKITIKLLTSIFLLALNWIPWSSYGMTTGVNSDYVDNVKQVFTHIDQKNWSQAEDLALEV
CEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHC
NNKVLTKIVLSQKYLDNKYSDNSFEHVIRFLRNNPDWPQNKRLEERAEEYLNNNTNKKVI
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEE
FDWFSKHPPVTGKGYKFYAAAASSLIKDQKILLPIIKEAWVYANFTPEEESVYYNKWHKY
EEEHHCCCCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHCEEEECCCCCCCCHHHHHHHHH
LTANDHLERIEEHLWQHDIRSAEQSLKYVDQGYRDSFKAQIAIIGKLPNAEKLFKNVPEK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHCCHH
YYTSGLLYRYLDSRKTQKPTSGDISLFKKAKNNRKHFAKWCRIQSYYAREFIDYKDFSNS
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
YRIATMPFATCPETIREQEWLAGWLSLSFLKKPDQALVHFNKFIKVVKTPISLARGFYWL
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
GRTYEAKGYKQTARKFYEQAAKYSFTFYGQVAHVELNRTKLVLPPIPVITSEARKNIENK
CCEECCCCHHHHHHHHHHHHHHCEEEEEEEEEEEEECCEEEEECCCCCEECHHHCCCCHH
EIIKAIRLLVKYNKHNLAMIYSKAAIKNTKNPAEIQIIANIIKANNNTNHMVEVAKIAAQ
HHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHC
NHAFIPDCAFPTPYNLGGLPIPPHLTYGIIRQESVFDHRAVSYANAMGLMQLIKGAACDT
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AKSINMKCNIADLTRNPVYNIKLGSHYFKKLLDDHKGSYILSIASYNAGSHNVVKWIDRF
CCCCCEEEEEEECCCCCEEEEEECHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHC
GDPRDIKDIRKVVDWIELIPYRETRDYVQRVLENIQIYRVILNKNNNLYFKRDLHACDIT
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEEEEECCCCEEEEECCCEECEE
KINFY
EEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]