Click here to switch to the map view.

The map label for this gene is nuoD [H]

Identifier: 157825613

GI number: 157825613

Start: 479801

End: 480985

Strand: Reverse

Name: nuoD [H]

Synonym: A1C_02650

Alternate gene names: 157825613

Gene position: 480985-479801 (Counterclockwise)

Preceding gene: 157825614

Following gene: 157825612

Centisome position: 39.07

GC content: 38.65

Gene sequence:

>1185_bases
ATGGATACTATGACTAACAACACAAAAACTATAACTCTAAATCTTGGTCCGCAGCATCCGGCAACTCATGGAGTTTTAAG
GTTAATTCTTGAGATGGATGGGGAAATAGTAAACAACGCCGATCCTCATATTGGGTTACTACATCGTGGTACGGAAAAGC
TTATTGAGCATAAAACATATTTGCAGGCTATACCATATTTTGATCGCCTTGATTATGTTTCACCAATGTGCCAAGAACAT
GCGTTTGCTTTGGCAGTTGAGTCGTTATTAGAATGCGAAGTCCCACGAAGAGCTCAGTTTATTAGGGTACTATTCTCAGA
ACTAACAAGAATTTTGAACCATACTTTGAATATTGGCAGCCAAGCTTTAGATATCGGTGCTACTACTCCTTTATTATGGC
TTTTTGAAGAGCGAGAAAAGATTATGGAATTTTACGAGCGTGTTTCCGGCTCTCGTATGCATTCAAACTACTTTAGACCT
GGGGGCGTTGCAGAAGATTTACCTGACGGTTTACTTGAAGATATAGATAAGTTTATAGATCAGTTTCCTCCTAAACTTCA
TGATATTGAAAGTCTATTAAATGAAAATAGATTATGGAAACAGCGGCTAGTAGATATCGGCGTTGTATCTCAAAAAGAGG
CGATGGATTGGGGGTTTTCAGGACCGATGCTTAGAGGCTCGGGCATAGCTTGGGATTTACGCAAGTCAAACCCTTATGAC
GTTTACGATGAAATGGAATTTGAAGTACCAATCGGCAAAAACGGTGATTGTTACGACAGATATTTCGTGCGTATGCTTGA
AATGTATGAATCTATTAAGATAATCAAGCAATGTATAGAGAAAATGCCGAAAGGTGCAGTTAAAACCAATGATCCTAAAT
TAACACCGCCGACAAGAGCCAAAATGAAAGAATCTATGGAAGCGATGATTCATCATTTTAAGCTCTATACGGCAGGATAT
GACGTCCCAGCCGGTGAGACTTATAAAGCAGTAGAAGCTCCTAAAGGCGAGTTTGGTGTATATTTATACTCGCAAGGAGT
TAATATACCTTATAGATGTCGTATTAAATCACCCGGCTTTGCTCATTTGCAAGGACTAGATTTTATGTCTAAAGGTCATT
TAATGGCAGATGTTATTACTATTATAGCTACGCTTGATATAGTATTTGGTGAGATAGATAGGTAG

Upstream 100 bases:

>100_bases
CTTATATAATGAAATTATTTAACTGGATTGCCGCGTAGCTTCGCTCTTCGCAATGACGGTTTGGGTCTCCGTGTAACAAC
ACCTACTGCTTCTCTCAATG

Downstream 100 bases:

>100_bases
ACTCGTTTACTACACTATTCATAATATTAGGAGTATATGAATACAAAAATTACAAATTTTACATTTGATAAGAAAAATTT
AAATCTAGCAGAAGATATTA

Product: NADH dehydrogenase subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D; NDH-1 subunit D [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MDTMTNNTKTITLNLGPQHPATHGVLRLILEMDGEIVNNADPHIGLLHRGTEKLIEHKTYLQAIPYFDRLDYVSPMCQEH
AFALAVESLLECEVPRRAQFIRVLFSELTRILNHTLNIGSQALDIGATTPLLWLFEEREKIMEFYERVSGSRMHSNYFRP
GGVAEDLPDGLLEDIDKFIDQFPPKLHDIESLLNENRLWKQRLVDIGVVSQKEAMDWGFSGPMLRGSGIAWDLRKSNPYD
VYDEMEFEVPIGKNGDCYDRYFVRMLEMYESIKIIKQCIEKMPKGAVKTNDPKLTPPTRAKMKESMEAMIHHFKLYTAGY
DVPAGETYKAVEAPKGEFGVYLYSQGVNIPYRCRIKSPGFAHLQGLDFMSKGHLMADVITIIATLDIVFGEIDR

Sequences:

>Translated_394_residues
MDTMTNNTKTITLNLGPQHPATHGVLRLILEMDGEIVNNADPHIGLLHRGTEKLIEHKTYLQAIPYFDRLDYVSPMCQEH
AFALAVESLLECEVPRRAQFIRVLFSELTRILNHTLNIGSQALDIGATTPLLWLFEEREKIMEFYERVSGSRMHSNYFRP
GGVAEDLPDGLLEDIDKFIDQFPPKLHDIESLLNENRLWKQRLVDIGVVSQKEAMDWGFSGPMLRGSGIAWDLRKSNPYD
VYDEMEFEVPIGKNGDCYDRYFVRMLEMYESIKIIKQCIEKMPKGAVKTNDPKLTPPTRAKMKESMEAMIHHFKLYTAGY
DVPAGETYKAVEAPKGEFGVYLYSQGVNIPYRCRIKSPGFAHLQGLDFMSKGHLMADVITIIATLDIVFGEIDR
>Mature_394_residues
MDTMTNNTKTITLNLGPQHPATHGVLRLILEMDGEIVNNADPHIGLLHRGTEKLIEHKTYLQAIPYFDRLDYVSPMCQEH
AFALAVESLLECEVPRRAQFIRVLFSELTRILNHTLNIGSQALDIGATTPLLWLFEEREKIMEFYERVSGSRMHSNYFRP
GGVAEDLPDGLLEDIDKFIDQFPPKLHDIESLLNENRLWKQRLVDIGVVSQKEAMDWGFSGPMLRGSGIAWDLRKSNPYD
VYDEMEFEVPIGKNGDCYDRYFVRMLEMYESIKIIKQCIEKMPKGAVKTNDPKLTPPTRAKMKESMEAMIHHFKLYTAGY
DVPAGETYKAVEAPKGEFGVYLYSQGVNIPYRCRIKSPGFAHLQGLDFMSKGHLMADVITIIATLDIVFGEIDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758786, Length=387, Percent_Identity=65.8914728682171, Blast_Score=552, Evalue=1e-157,
Organism=Homo sapiens, GI260898743, Length=381, Percent_Identity=65.3543307086614, Blast_Score=537, Evalue=1e-153,
Organism=Escherichia coli, GI145693162, Length=395, Percent_Identity=38.9873417721519, Blast_Score=317, Evalue=6e-88,
Organism=Escherichia coli, GI1789076, Length=390, Percent_Identity=26.6666666666667, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1788832, Length=390, Percent_Identity=26.6666666666667, Blast_Score=114, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17555284, Length=389, Percent_Identity=60.1542416452442, Blast_Score=523, Evalue=1e-149,
Organism=Caenorhabditis elegans, GI17568379, Length=389, Percent_Identity=59.3830334190231, Blast_Score=518, Evalue=1e-147,
Organism=Drosophila melanogaster, GI24638644, Length=389, Percent_Identity=63.4961439588689, Blast_Score=553, Evalue=1e-158,
Organism=Drosophila melanogaster, GI221459469, Length=386, Percent_Identity=60.6217616580311, Blast_Score=516, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885 [H]

Pfam domain/function: PF00346 Complex1_49kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 44995; Mature: 44995

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTMTNNTKTITLNLGPQHPATHGVLRLILEMDGEIVNNADPHIGLLHRGTEKLIEHKTY
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEHHHCCHHHHHHHHHH
LQAIPYFDRLDYVSPMCQEHAFALAVESLLECEVPRRAQFIRVLFSELTRILNHTLNIGS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
QALDIGATTPLLWLFEEREKIMEFYERVSGSRMHSNYFRPGGVAEDLPDGLLEDIDKFID
HHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHCHHHHHHHHHHHHH
QFPPKLHDIESLLNENRLWKQRLVDIGVVSQKEAMDWGFSGPMLRGSGIAWDLRKSNPYD
HCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCEEEECCCCCCC
VYDEMEFEVPIGKNGDCYDRYFVRMLEMYESIKIIKQCIEKMPKGAVKTNDPKLTPPTRA
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
KMKESMEAMIHHFKLYTAGYDVPAGETYKAVEAPKGEFGVYLYSQGVNIPYRCRIKSPGF
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCEEEEECCCCC
AHLQGLDFMSKGHLMADVITIIATLDIVFGEIDR
HHHHCCCHHHCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDTMTNNTKTITLNLGPQHPATHGVLRLILEMDGEIVNNADPHIGLLHRGTEKLIEHKTY
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEHHHCCHHHHHHHHHH
LQAIPYFDRLDYVSPMCQEHAFALAVESLLECEVPRRAQFIRVLFSELTRILNHTLNIGS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
QALDIGATTPLLWLFEEREKIMEFYERVSGSRMHSNYFRPGGVAEDLPDGLLEDIDKFID
HHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHCHHHHHHHHHHHHH
QFPPKLHDIESLLNENRLWKQRLVDIGVVSQKEAMDWGFSGPMLRGSGIAWDLRKSNPYD
HCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCEEEECCCCCCC
VYDEMEFEVPIGKNGDCYDRYFVRMLEMYESIKIIKQCIEKMPKGAVKTNDPKLTPPTRA
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
KMKESMEAMIHHFKLYTAGYDVPAGETYKAVEAPKGEFGVYLYSQGVNIPYRCRIKSPGF
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCEEEEECCCCC
AHLQGLDFMSKGHLMADVITIIATLDIVFGEIDR
HHHHCCCHHHCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA