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The map label for this gene is nuoE [H]

Identifier: 157825612

GI number: 157825612

Start: 479261

End: 479764

Strand: Reverse

Name: nuoE [H]

Synonym: A1C_02645

Alternate gene names: 157825612

Gene position: 479764-479261 (Counterclockwise)

Preceding gene: 157825613

Following gene: 157825611

Centisome position: 38.97

GC content: 32.94

Gene sequence:

>504_bases
ATGAATACAAAAATTACAAATTTTACATTTGATAAGAAAAATTTAAATCTAGCAGAAGATATTATAAAAAAATATCCACC
AGAAGGTAAAAGAAGTGCTATATTACCACTGCTTGATTTAGCACAACGTCAAAATGGAGGTTGGCTACCAGTGCCTGCTA
TCGAATATGTCGCAAATATGCTAGAAATGCCTTATATGCGCGCTTATGAAGTTGCAACTTTTTATACTATGTTTAACTTA
AAGCGAGTTGGTAAATATCATATTCACGTATGTACTACTACCCCTTGCTGGCTACGCGGTAGTGATGATATAATGAAAAT
TTGTAAAAAGAAATTAGGTATAAAACTCAAAGAAACCACGGAAGATCAAAAATTTACTTTAAGCGAGATAGAGTGTTTAG
GAGCATGCGTTAACGCTCCGGTCTTACAAATCAATGACGATTATTATGAAGATCTGACTCCAGAAAAAATGGAAAAACTA
ATAGATAGGTTGCAAAATGAGTAA

Upstream 100 bases:

>100_bases
AATGGCAGATGTTATTACTATTATAGCTACGCTTGATATAGTATTTGGTGAGATAGATAGGTAGACTCGTTTACTACACT
ATTCATAATATTAGGAGTAT

Downstream 100 bases:

>100_bases
AATACTTTTATTAATAGTTAAGTTTTATCAATATTTCATTTCCCCGCTACTTGGCAATAATTGCCGATTTCACCCATCCT
GTTCTGAATATGCCAAAGAA

Product: NADH dehydrogenase subunit E

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MNTKITNFTFDKKNLNLAEDIIKKYPPEGKRSAILPLLDLAQRQNGGWLPVPAIEYVANMLEMPYMRAYEVATFYTMFNL
KRVGKYHIHVCTTTPCWLRGSDDIMKICKKKLGIKLKETTEDQKFTLSEIECLGACVNAPVLQINDDYYEDLTPEKMEKL
IDRLQNE

Sequences:

>Translated_167_residues
MNTKITNFTFDKKNLNLAEDIIKKYPPEGKRSAILPLLDLAQRQNGGWLPVPAIEYVANMLEMPYMRAYEVATFYTMFNL
KRVGKYHIHVCTTTPCWLRGSDDIMKICKKKLGIKLKETTEDQKFTLSEIECLGACVNAPVLQINDDYYEDLTPEKMEKL
IDRLQNE
>Mature_167_residues
MNTKITNFTFDKKNLNLAEDIIKKYPPEGKRSAILPLLDLAQRQNGGWLPVPAIEYVANMLEMPYMRAYEVATFYTMFNL
KRVGKYHIHVCTTTPCWLRGSDDIMKICKKKLGIKLKETTEDQKFTLSEIECLGACVNAPVLQINDDYYEDLTPEKMEKL
IDRLQNE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=164, Percent_Identity=60.9756097560976, Blast_Score=205, Evalue=1e-53,
Organism=Escherichia coli, GI1788621, Length=136, Percent_Identity=36.7647058823529, Blast_Score=92, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17561328, Length=158, Percent_Identity=57.5949367088608, Blast_Score=193, Evalue=3e-50,
Organism=Drosophila melanogaster, GI18859877, Length=160, Percent_Identity=60.625, Blast_Score=209, Evalue=5e-55,
Organism=Drosophila melanogaster, GI21355353, Length=164, Percent_Identity=46.9512195121951, Blast_Score=157, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 19344; Mature: 19344

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKITNFTFDKKNLNLAEDIIKKYPPEGKRSAILPLLDLAQRQNGGWLPVPAIEYVANM
CCCCCCEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LEMPYMRAYEVATFYTMFNLKRVGKYHIHVCTTTPCWLRGSDDIMKICKKKLGIKLKETT
HHCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCEECCCHHHHHHHHHHHCCEEECCC
EDQKFTLSEIECLGACVNAPVLQINDDYYEDLTPEKMEKLIDRLQNE
CCCHHHHHHHHHHHHHHCCCEEEECCCHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTKITNFTFDKKNLNLAEDIIKKYPPEGKRSAILPLLDLAQRQNGGWLPVPAIEYVANM
CCCCCCEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LEMPYMRAYEVATFYTMFNLKRVGKYHIHVCTTTPCWLRGSDDIMKICKKKLGIKLKETT
HHCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCEECCCHHHHHHHHHHHCCEEECCC
EDQKFTLSEIECLGACVNAPVLQINDDYYEDLTPEKMEKLIDRLQNE
CCCHHHHHHHHHHHHHHCCCEEEECCCHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]