Click here to switch to the map view.

The map label for this gene is rbsK [H]

Identifier: 157373128

GI number: 157373128

Start: 5433470

End: 5434426

Strand: Reverse

Name: rbsK [H]

Synonym: Spro_4897

Alternate gene names: 157373128

Gene position: 5434426-5433470 (Counterclockwise)

Preceding gene: 157373129

Following gene: 157373127

Centisome position: 99.74

GC content: 57.37

Gene sequence:

>957_bases
ATGATGGCGCACAATTCAGGAATCAATGCGATGGCAACAGGTAAGCTGGTGGTTTTGGGCAGTATCAATGCCGACCATAT
CCTCAATATTGAGCAGTTTCCCCGCCCGGGTGAAACGGTGATCGGGAAGCAGTATAAAGTGGCGTTTGGCGGCAAAGGCG
CCAACCAGGCGGTGGCGGCAGGGCGCAGCGGCGCGGATATCGCTTTTATCGCCTGCGTGGGCGCTGATGACATCGGCGAA
CGCATTCGTCAGCAACTGGCTACCGATCGCATTGATACCCAACCGATAGAGGCGATTGCCGAAAACACGACCGGCGTAGC
GCTGATTTTTGTTAATGCTGAAGGCGAGAACGTGATCGGCATTGATGCCGGCGCCAATGCGGCAGTGACTCCTGACTATC
TGGCTCGCTATCAGCAAAAAGTGATCGATGCCGATGCGTTGTTGATGCAGCTCGAGTCGCCGCTGGAGACGGTTATCGCC
GCCGCCGGCCTGGCGAAACAGCATCAGACTCAGGTGATCCTCAATCCTGCGCCGGCACGTGAACTGCCGGACGAATTATT
GGCAATGATCGATATGATTACGCCAAACGAAACCGAAGCCCAGCGCCTGACCGGTATTGCGGTCAATAATGATGATGATG
CCGCGCGTGCCGCACAGGCTTTGCATGATAAAGGCATTGCCACTGTGATCATCACCCTCGGCAGCCGTGGCGTTTGGCTG
AGTGAAAACGGCAAGGGTAAGCTGGTGCCCGGCTTCAGGGTTAAAGCCGTAGACACCATTGCTGCCGGTGATACCTTCAA
CGGGGCGCTGGTCACGGCGCTGCTGGAAGGCAAAACCATGGCGGATGCGGTACGCTTTGCCCATGCGGCGGCGGCCATTG
CGGTGACCCGTCCAGGTGCTCAGCCTTCCGTACCCTGGCGCGAAGAGATCGACATCTTCTTGCAGCAGCAGGAGTAA

Upstream 100 bases:

>100_bases
GTGTTGAAAGGCGAAAAAGTGCCGGCCACTATCCCGGTTGATCTGAAACTGGTCACTAAATAACACTCTGTAGCACCAGC
GCCATCAAAACGGGGCGTTT

Downstream 100 bases:

>100_bases
TCCCCTTGGCCACCATGAAAGACGTCGCCCGCCTGGCGGGCGTTTCAACCTCGACGGTCTCGCACGTCATTAATGACAAT
CGCTTTGTCAGCGACAGCGT

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MMAHNSGINAMATGKLVVLGSINADHILNIEQFPRPGETVIGKQYKVAFGGKGANQAVAAGRSGADIAFIACVGADDIGE
RIRQQLATDRIDTQPIEAIAENTTGVALIFVNAEGENVIGIDAGANAAVTPDYLARYQQKVIDADALLMQLESPLETVIA
AAGLAKQHQTQVILNPAPARELPDELLAMIDMITPNETEAQRLTGIAVNNDDDAARAAQALHDKGIATVIITLGSRGVWL
SENGKGKLVPGFRVKAVDTIAAGDTFNGALVTALLEGKTMADAVRFAHAAAAIAVTRPGAQPSVPWREEIDIFLQQQE

Sequences:

>Translated_318_residues
MMAHNSGINAMATGKLVVLGSINADHILNIEQFPRPGETVIGKQYKVAFGGKGANQAVAAGRSGADIAFIACVGADDIGE
RIRQQLATDRIDTQPIEAIAENTTGVALIFVNAEGENVIGIDAGANAAVTPDYLARYQQKVIDADALLMQLESPLETVIA
AAGLAKQHQTQVILNPAPARELPDELLAMIDMITPNETEAQRLTGIAVNNDDDAARAAQALHDKGIATVIITLGSRGVWL
SENGKGKLVPGFRVKAVDTIAAGDTFNGALVTALLEGKTMADAVRFAHAAAAIAVTRPGAQPSVPWREEIDIFLQQQE
>Mature_318_residues
MMAHNSGINAMATGKLVVLGSINADHILNIEQFPRPGETVIGKQYKVAFGGKGANQAVAAGRSGADIAFIACVGADDIGE
RIRQQLATDRIDTQPIEAIAENTTGVALIFVNAEGENVIGIDAGANAAVTPDYLARYQQKVIDADALLMQLESPLETVIA
AAGLAKQHQTQVILNPAPARELPDELLAMIDMITPNETEAQRLTGIAVNNDDDAARAAQALHDKGIATVIITLGSRGVWL
SENGKGKLVPGFRVKAVDTIAAGDTFNGALVTALLEGKTMADAVRFAHAAAAIAVTRPGAQPSVPWREEIDIFLQQQE

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=300, Percent_Identity=35.6666666666667, Blast_Score=162, Evalue=3e-40,
Organism=Escherichia coli, GI1790193, Length=304, Percent_Identity=73.3552631578947, Blast_Score=430, Evalue=1e-122,
Organism=Escherichia coli, GI87082343, Length=311, Percent_Identity=31.5112540192926, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI87081971, Length=308, Percent_Identity=26.9480519480519, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1788491, Length=262, Percent_Identity=25.1908396946565, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788417, Length=305, Percent_Identity=27.5409836065574, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788484, Length=281, Percent_Identity=26.3345195729537, Blast_Score=71, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17532905, Length=305, Percent_Identity=38.6885245901639, Blast_Score=179, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6319884, Length=327, Percent_Identity=28.4403669724771, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI20128807, Length=308, Percent_Identity=36.6883116883117, Blast_Score=147, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24583886, Length=301, Percent_Identity=32.5581395348837, Blast_Score=141, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 33398; Mature: 33398

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAHNSGINAMATGKLVVLGSINADHILNIEQFPRPGETVIGKQYKVAFGGKGANQAVAA
CCCCCCCCCEEECCCEEEEECCCCCCEECHHHCCCCCCCCCCCEEEEEECCCCCCHHHHC
GRSGADIAFIACVGADDIGERIRQQLATDRIDTQPIEAIAENTTGVALIFVNAEGENVIG
CCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEEECCCCEEEE
IDAGANAAVTPDYLARYQQKVIDADALLMQLESPLETVIAAAGLAKQHQTQVILNPAPAR
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
ELPDELLAMIDMITPNETEAQRLTGIAVNNDDDAARAAQALHDKGIATVIITLGSRGVWL
CCHHHHHHHHHHCCCCCCHHHHEEEEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCEEE
SENGKGKLVPGFRVKAVDTIAAGDTFNGALVTALLEGKTMADAVRFAHAAAAIAVTRPGA
CCCCCEEECCCEEEEEEEEEECCCCCCCHHEEEECCCCHHHHHHHHHHHHHEEEEECCCC
QPSVPWREEIDIFLQQQE
CCCCCCHHCEEEEEECCC
>Mature Secondary Structure
MMAHNSGINAMATGKLVVLGSINADHILNIEQFPRPGETVIGKQYKVAFGGKGANQAVAA
CCCCCCCCCEEECCCEEEEECCCCCCEECHHHCCCCCCCCCCCEEEEEECCCCCCHHHHC
GRSGADIAFIACVGADDIGERIRQQLATDRIDTQPIEAIAENTTGVALIFVNAEGENVIG
CCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEEEECCCCEEEE
IDAGANAAVTPDYLARYQQKVIDADALLMQLESPLETVIAAAGLAKQHQTQVILNPAPAR
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
ELPDELLAMIDMITPNETEAQRLTGIAVNNDDDAARAAQALHDKGIATVIITLGSRGVWL
CCHHHHHHHHHHCCCCCCHHHHEEEEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCEEE
SENGKGKLVPGFRVKAVDTIAAGDTFNGALVTALLEGKTMADAVRFAHAAAAIAVTRPGA
CCCCCEEECCCEEEEEEEEEECCCCCCCHHEEEECCCCHHHHHHHHHHHHHEEEEECCCC
QPSVPWREEIDIFLQQQE
CCCCCCHHCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]