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The map label for this gene is argB

Identifier: 157373012

GI number: 157373012

Start: 5295460

End: 5296233

Strand: Reverse

Name: argB

Synonym: Spro_4780

Alternate gene names: 157373012

Gene position: 5296233-5295460 (Counterclockwise)

Preceding gene: 157373013

Following gene: 157373011

Centisome position: 97.2

GC content: 59.17

Gene sequence:

>774_bases
ATGAATCCGTTAATTATCAAGTTAGGTGGCGTGTTATTAGACAGTGAAGAGGCGCTGGAGCGTCTGTTTACCGCACTGGA
CAGCTACCGTCAGCAGCATCAGCGCCCGTTGGTGATCGTTCACGGCGGCGGTTGCCTGGTCGATGAACTGATGAAAAAGC
TTTCCCTGCCGGTGGTGAAGAAAAATGGCCTGCGTGTGACCCCGGCCGATCAGATTGACATTATTACCGGCGCGCTGGCC
GGCACCGCCAACAAAACCTTGCTGGCGTGGGCCATCAAGCACCAGATTAACGCGGTTGGCCTGAGCCTGGCGGACGGTGG
CAGCGTCACCGTCACCCCGCTCGATCCGGCGCTGGGCCACGTGGGCAATGCGCAACCGGGCTCCCCGCTGTTGCTCAATA
CCCTGCTGGGCGCCGGTTATCTGCCGGTGATCAGTTCCATCGGTATTACCGCCGATGGGCAGTTAATGAATGTGAACGCC
GATCAGGCGGCGACGGCTCTGGCCGCCACCCTGGGTGCGGATTTGATCCTGCTGTCGGATGTCAGTGGCATCCTCGATGG
AAAAGGGCAACGCATCGCAGAAATGACGGCGCAAAAAGCGGAACAACTGATTGCCCAGGGCATCATCACTGATGGTATGG
TGGTGAAGGTGAATGCGGCGCTCGATGCGGCCCGCACCCTCGGTCGCCCGGTAGATATCGCCAGTTGGCGCCATGCCGAT
CAGCTTCCTGCACTGTTTAACGGCGTGTCAATTGGCACCCGGATCCTCGCTTAA

Upstream 100 bases:

>100_bases
GCGCAGCCGCTCAGGCGGTGCAATGCCTGAATATCCGTTTTGGGTTCCCTGAAACCCAGTCATTACTTTAATAAATCACC
AGCGTGGGATGTAAACAGCG

Downstream 100 bases:

>100_bases
ATATAGAATTAAAAAGGAAAAGACCATGCAAAACCAAGGCATCAAAAAAATCGTTCTGGCGTACTCTGGCGGTCTGGATA
CTTCGGCCATCATTCCCTGG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MNPLIIKLGGVLLDSEEALERLFTALDSYRQQHQRPLVIVHGGGCLVDELMKKLSLPVVKKNGLRVTPADQIDIITGALA
GTANKTLLAWAIKHQINAVGLSLADGGSVTVTPLDPALGHVGNAQPGSPLLLNTLLGAGYLPVISSIGITADGQLMNVNA
DQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARTLGRPVDIASWRHAD
QLPALFNGVSIGTRILA

Sequences:

>Translated_257_residues
MNPLIIKLGGVLLDSEEALERLFTALDSYRQQHQRPLVIVHGGGCLVDELMKKLSLPVVKKNGLRVTPADQIDIITGALA
GTANKTLLAWAIKHQINAVGLSLADGGSVTVTPLDPALGHVGNAQPGSPLLLNTLLGAGYLPVISSIGITADGQLMNVNA
DQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARTLGRPVDIASWRHAD
QLPALFNGVSIGTRILA
>Mature_257_residues
MNPLIIKLGGVLLDSEEALERLFTALDSYRQQHQRPLVIVHGGGCLVDELMKKLSLPVVKKNGLRVTPADQIDIITGALA
GTANKTLLAWAIKHQINAVGLSLADGGSVTVTPLDPALGHVGNAQPGSPLLLNTLLGAGYLPVISSIGITADGQLMNVNA
DQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARTLGRPVDIASWRHAD
QLPALFNGVSIGTRILA

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=257, Percent_Identity=86.3813229571984, Blast_Score=416, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_SERP5 (A8GL83)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001481001.1
- ProteinModelPortal:   A8GL83
- SMR:   A8GL83
- STRING:   A8GL83
- GeneID:   5604720
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_4780
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MVLCGST
- ProtClustDB:   PRK00942
- BioCyc:   SPRO399741:SPRO_4780-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 26642; Mature: 26642

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: BINDING 65-65 BINDING 157-157

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLIIKLGGVLLDSEEALERLFTALDSYRQQHQRPLVIVHGGGCLVDELMKKLSLPVVK
CCCEEEEECCEEECCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCEEC
KNGLRVTPADQIDIITGALAGTANKTLLAWAIKHQINAVGLSLADGGSVTVTPLDPALGH
CCCEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEEECCCEEEEEECCHHHCC
VGNAQPGSPLLLNTLLGAGYLPVISSIGITADGQLMNVNADQAATALAATLGADLILLSD
CCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHCCCEEEEEC
VSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARTLGRPVDIASWRHAD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHCCCCCCHHCCCCCH
QLPALFNGVSIGTRILA
HCHHHHCCHHHHHEECC
>Mature Secondary Structure
MNPLIIKLGGVLLDSEEALERLFTALDSYRQQHQRPLVIVHGGGCLVDELMKKLSLPVVK
CCCEEEEECCEEECCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCEEC
KNGLRVTPADQIDIITGALAGTANKTLLAWAIKHQINAVGLSLADGGSVTVTPLDPALGH
CCCEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEEECCCEEEEEECCHHHCC
VGNAQPGSPLLLNTLLGAGYLPVISSIGITADGQLMNVNADQAATALAATLGADLILLSD
CCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHCCCEEEEEC
VSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARTLGRPVDIASWRHAD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHCCCCCCHHCCCCCH
QLPALFNGVSIGTRILA
HCHHHHCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA