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The map label for this gene is argC [H]

Identifier: 157373013

GI number: 157373013

Start: 5296263

End: 5297267

Strand: Reverse

Name: argC [H]

Synonym: Spro_4781

Alternate gene names: 157373013

Gene position: 5297267-5296263 (Counterclockwise)

Preceding gene: 157373016

Following gene: 157373012

Centisome position: 97.22

GC content: 57.71

Gene sequence:

>1005_bases
ATGTTGAATACGCTGATTGTCGGTGCCAGCGGTTATGCCGGAGCAGAGCTCACGGCGTACCTTAATCGTCACCCACACAT
GAACATAACCGCTTTAGCGGTTTCAGCGCAAAGTGCAGATGCAGGAAAATTGCTTTCCGATTTGCACCCCCAGTTAAAAG
GCATCGTCGATCTCCCCTTGCAGCCGCTGGTTGACGTAGCCGCCGCCGCCGCTGGTATCGACGTAGTGTTCCTGGCGACG
GCACACGAGGTCAGCCACGATATCGCGCCGGCGTTTCTGGCCGCAGGTTGCGTGGTGTTCGATCTCTCCGGCGCATTCCG
CGTGAAAGATACCGCCTTCTACAGCCAATATTACGGTTTTGAACATCAGCATGCCGACTTGCTGGAGCAGGCGGTGTATG
GCCTGGCGGAATGGCAGAGCGACAAAATCAAACAGGCTCAGCTGATCGCCGTACCGGGCTGTTATCCGACGGCGGCACAG
TTGGCGCTGAAACCGTTGATCGACCAGGAGTTGCTGAATCTTGATCAGTGGCCGGTGATCAACGCGACCAGCGGCGTCAG
CGGTGCGGGCCGCAAGGCCAGCGTGACCACCAGTTTCTGTGAGGTGAGCCTGCAGCCGTACGGTATTTTCAACCACCGTC
ACCATCCGGAAATCGTCGCGCATTTGGGCGTGCCGGTCATTTTTACGCCACATTTGGGTAACTTCCCGCGTGGTATTCTC
GAAACCATTACCTGTCGCCTGAAAGCCGGTGTGACCGCGCAGGATGTGGCTGCCGTTTATCACGCCGCCTATGACGACAA
ACCGCTGGTGCGGCTGTACGACCAGGGCGTACCGGCATTGAAGTCAGTCGTCGGGCTGCCGTTCTGCGACATCGGCTTTG
CCGTGCAGGGCGAACACCTGATTGCCGTGGCGGCGGAAGACAACCTGTTGAAAGGCGCAGCCGCTCAGGCGGTGCAATGC
CTGAATATCCGTTTTGGGTTCCCTGAAACCCAGTCATTACTTTAA

Upstream 100 bases:

>100_bases
TCAACGCTCGACCTCGTGGGTGAACGGCAAAACAACGCTGGTGAGCCTGGAAACCTGAGTCGAATACGACCCAACGCAAG
TCTAGAAGGTGAAAGGCCCC

Downstream 100 bases:

>100_bases
TAAATCACCAGCGTGGGATGTAAACAGCGATGAATCCGTTAATTATCAAGTTAGGTGGCGTGTTATTAGACAGTGAAGAG
GCGCTGGAGCGTCTGTTTAC

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MLNTLIVGASGYAGAELTAYLNRHPHMNITALAVSAQSADAGKLLSDLHPQLKGIVDLPLQPLVDVAAAAAGIDVVFLAT
AHEVSHDIAPAFLAAGCVVFDLSGAFRVKDTAFYSQYYGFEHQHADLLEQAVYGLAEWQSDKIKQAQLIAVPGCYPTAAQ
LALKPLIDQELLNLDQWPVINATSGVSGAGRKASVTTSFCEVSLQPYGIFNHRHHPEIVAHLGVPVIFTPHLGNFPRGIL
ETITCRLKAGVTAQDVAAVYHAAYDDKPLVRLYDQGVPALKSVVGLPFCDIGFAVQGEHLIAVAAEDNLLKGAAAQAVQC
LNIRFGFPETQSLL

Sequences:

>Translated_334_residues
MLNTLIVGASGYAGAELTAYLNRHPHMNITALAVSAQSADAGKLLSDLHPQLKGIVDLPLQPLVDVAAAAAGIDVVFLAT
AHEVSHDIAPAFLAAGCVVFDLSGAFRVKDTAFYSQYYGFEHQHADLLEQAVYGLAEWQSDKIKQAQLIAVPGCYPTAAQ
LALKPLIDQELLNLDQWPVINATSGVSGAGRKASVTTSFCEVSLQPYGIFNHRHHPEIVAHLGVPVIFTPHLGNFPRGIL
ETITCRLKAGVTAQDVAAVYHAAYDDKPLVRLYDQGVPALKSVVGLPFCDIGFAVQGEHLIAVAAEDNLLKGAAAQAVQC
LNIRFGFPETQSLL
>Mature_334_residues
MLNTLIVGASGYAGAELTAYLNRHPHMNITALAVSAQSADAGKLLSDLHPQLKGIVDLPLQPLVDVAAAAAGIDVVFLAT
AHEVSHDIAPAFLAAGCVVFDLSGAFRVKDTAFYSQYYGFEHQHADLLEQAVYGLAEWQSDKIKQAQLIAVPGCYPTAAQ
LALKPLIDQELLNLDQWPVINATSGVSGAGRKASVTTSFCEVSLQPYGIFNHRHHPEIVAHLGVPVIFTPHLGNFPRGIL
ETITCRLKAGVTAQDVAAVYHAAYDDKPLVRLYDQGVPALKSVVGLPFCDIGFAVQGEHLIAVAAEDNLLKGAAAQAVQC
LNIRFGFPETQSLL

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=334, Percent_Identity=79.940119760479, Blast_Score=553, Evalue=1e-159,
Organism=Saccharomyces cerevisiae, GI6320913, Length=333, Percent_Identity=28.2282282282282, Blast_Score=108, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 35592; Mature: 35592

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS01224 ARGC ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNTLIVGASGYAGAELTAYLNRHPHMNITALAVSAQSADAGKLLSDLHPQLKGIVDLPL
CCCEEEEECCCCCCCHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCHHHHHHHCCCC
QPLVDVAAAAAGIDVVFLATAHEVSHDIAPAFLAAGCVVFDLSGAFRVKDTAFYSQYYGF
HHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHCCEEEEECCCCEEEHHHHHHHHHCCC
EHQHADLLEQAVYGLAEWQSDKIKQAQLIAVPGCYPTAAQLALKPLIDQELLNLDQWPVI
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEE
NATSGVSGAGRKASVTTSFCEVSLQPYGIFNHRHHPEIVAHLGVPVIFTPHLGNFPRGIL
ECCCCCCCCCCCCEEEEHHHEEECCCEEECCCCCCHHHHHHCCCCEEECCCCCCCCHHHH
ETITCRLKAGVTAQDVAAVYHAAYDDKPLVRLYDQGVPALKSVVGLPFCDIGFAVQGEHL
HHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHCCCCCCCCCEECCCEE
IAVAAEDNLLKGAAAQAVQCLNIRFGFPETQSLL
EEEECCCCHHHHHHHHHHHHEEEEECCCCHHHCC
>Mature Secondary Structure
MLNTLIVGASGYAGAELTAYLNRHPHMNITALAVSAQSADAGKLLSDLHPQLKGIVDLPL
CCCEEEEECCCCCCCHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCHHHHHHHCCCC
QPLVDVAAAAAGIDVVFLATAHEVSHDIAPAFLAAGCVVFDLSGAFRVKDTAFYSQYYGF
HHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHCCEEEEECCCCEEEHHHHHHHHHCCC
EHQHADLLEQAVYGLAEWQSDKIKQAQLIAVPGCYPTAAQLALKPLIDQELLNLDQWPVI
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEE
NATSGVSGAGRKASVTTSFCEVSLQPYGIFNHRHHPEIVAHLGVPVIFTPHLGNFPRGIL
ECCCCCCCCCCCCEEEEHHHEEECCCEEECCCCCCHHHHHHCCCCEEECCCCCCCCHHHH
ETITCRLKAGVTAQDVAAVYHAAYDDKPLVRLYDQGVPALKSVVGLPFCDIGFAVQGEHL
HHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHCCCCCCCCCEECCCEE
IAVAAEDNLLKGAAAQAVQCLNIRFGFPETQSLL
EEEECCCCHHHHHHHHHHHHEEEEECCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]