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The map label for this gene is yhjE [H]

Identifier: 157372977

GI number: 157372977

Start: 5248845

End: 5250167

Strand: Direct

Name: yhjE [H]

Synonym: Spro_4745

Alternate gene names: 157372977

Gene position: 5248845-5250167 (Clockwise)

Preceding gene: 157372976

Following gene: 157372978

Centisome position: 96.33

GC content: 60.24

Gene sequence:

>1323_bases
ATGCAAGCCTCCATCGCACCAACTCTGGACGCCGACGACGCGCCAACACCAGTCAACTCACGCGGAAAAGTGATTGTCGC
CTCGCTGGTCGGGACCGCCATCGAGTTTTTCGATTTCTATATTTACGCCACCGCGGCGGTGATCGTATTCCCGCATATCT
TCTTCCCGCAGGGCGATCCCACCACCGCAACGCTACAGTCGTTGGCCACCTTTGCCGTCGCCTTTGTGGCGCGTCCGATT
GGCTCGGCGCTGTTCGGCCACTTTGGCGATCGCGTGGGGCGCAAGGTGACGCTGGTCGCCTCGCTGCTCACCATGGGGAT
TTCCACCGTGCTGATCGGCCTGCTGCCAAGCTACGAAACCATCGGCATCTTCGCCCCTATCCTGCTGGCGCTGGCGCGAT
TCGGTCAGGGCCTGGGGCTGGGGGGTGAATGGGGCGGAGCCGCCTTGCTGGCAACCGAGAACGCCCCTCCCAAGAAGCGG
GCGCTGTATGGTTCGTTCCCACAGCTGGGCGCGCCTATCGGTTTCTTCTTCGCTAACGGCACCTTCCTGCTGCTCTCCTG
GCTGCTGACTGACCAACAATTTATGGAATGGGGCTGGCGCGTGCCGTTTATCCTGTCCGCCGCCCTGGTGCTGATCGGCC
TGTACGTGCGCGTGTCGCTGCATGAAACTCCGGTATTCGCCAAGGTGGCCAAAGCCGGCAAACAGGTGAAAATCCCGCTC
GGTACCCTGCTGAGCAAGCATTTGAAGGCGACCATCCTCGGCACCTTTATCATGCTGGCGACCTATACCCTGTTCTACCT
GATGACGGTTTACTCAATGACCTACGGCACCACGGCGCAGCCGCTGGGGCTGGGTTACTCGCGCAACAGTTTCCTGTGGA
TGCTGATGGTGGCAGTGATTGGTTTTGGTGTGATGGTGCCGATTGCCGGCCTGCTGGCCGATGCCTTTGGTCGCCGCAAG
ACCATGATCGTTATCACTCTGCTGATGATCGCCTTCGCCTTCCTGTTCCCAAGTATGCTGGGCTCCGGTAACCAGGCGCT
GGTGATGGGCTTCCTGCTGTGTGGTCTGAGCATCATGGGCCTGACCTTCGGCCCGATGGGCGCACTGCTGCCAGAGCTGT
TCCCGACCGAAGTGCGTTATACCGGGGCTTCGTTCTCGTACAACGTGGCGTCAATCCTCGGGGCGGCAGTGGCACCTTAT
ATCGCTACCTGGCTGGCAACCCACTACGGCCTGTTCTACGTCGGTCTGTATCTGGCATCCATGGCCTGTCTCACGCTGAT
AGCCCTGTTGCTGATGAAAGAAACCCGCGACCAGTCGCTGTAA

Upstream 100 bases:

>100_bases
TTAACCGGTTAATTGCGGCATTGTACAAAGTTTCACCATTGAAAAGGCATTTTGCTATGACTAAGATGGATTTTTACCAA
TCCAAAATATAAGAAAAATT

Downstream 100 bases:

>100_bases
CCCTGCTTATGCGGCCCCTGCCTGCGGGCCGCACTCCCCGCGTTGTCTCCTGTCATAAAATCAGACTATGCTGAATGCTT
CTCCTTTTACGGAAATGGAA

Product: major facilitator superfamily metabolite/H(+) symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MQASIAPTLDADDAPTPVNSRGKVIVASLVGTAIEFFDFYIYATAAVIVFPHIFFPQGDPTTATLQSLATFAVAFVARPI
GSALFGHFGDRVGRKVTLVASLLTMGISTVLIGLLPSYETIGIFAPILLALARFGQGLGLGGEWGGAALLATENAPPKKR
ALYGSFPQLGAPIGFFFANGTFLLLSWLLTDQQFMEWGWRVPFILSAALVLIGLYVRVSLHETPVFAKVAKAGKQVKIPL
GTLLSKHLKATILGTFIMLATYTLFYLMTVYSMTYGTTAQPLGLGYSRNSFLWMLMVAVIGFGVMVPIAGLLADAFGRRK
TMIVITLLMIAFAFLFPSMLGSGNQALVMGFLLCGLSIMGLTFGPMGALLPELFPTEVRYTGASFSYNVASILGAAVAPY
IATWLATHYGLFYVGLYLASMACLTLIALLLMKETRDQSL

Sequences:

>Translated_440_residues
MQASIAPTLDADDAPTPVNSRGKVIVASLVGTAIEFFDFYIYATAAVIVFPHIFFPQGDPTTATLQSLATFAVAFVARPI
GSALFGHFGDRVGRKVTLVASLLTMGISTVLIGLLPSYETIGIFAPILLALARFGQGLGLGGEWGGAALLATENAPPKKR
ALYGSFPQLGAPIGFFFANGTFLLLSWLLTDQQFMEWGWRVPFILSAALVLIGLYVRVSLHETPVFAKVAKAGKQVKIPL
GTLLSKHLKATILGTFIMLATYTLFYLMTVYSMTYGTTAQPLGLGYSRNSFLWMLMVAVIGFGVMVPIAGLLADAFGRRK
TMIVITLLMIAFAFLFPSMLGSGNQALVMGFLLCGLSIMGLTFGPMGALLPELFPTEVRYTGASFSYNVASILGAAVAPY
IATWLATHYGLFYVGLYLASMACLTLIALLLMKETRDQSL
>Mature_440_residues
MQASIAPTLDADDAPTPVNSRGKVIVASLVGTAIEFFDFYIYATAAVIVFPHIFFPQGDPTTATLQSLATFAVAFVARPI
GSALFGHFGDRVGRKVTLVASLLTMGISTVLIGLLPSYETIGIFAPILLALARFGQGLGLGGEWGGAALLATENAPPKKR
ALYGSFPQLGAPIGFFFANGTFLLLSWLLTDQQFMEWGWRVPFILSAALVLIGLYVRVSLHETPVFAKVAKAGKQVKIPL
GTLLSKHLKATILGTFIMLATYTLFYLMTVYSMTYGTTAQPLGLGYSRNSFLWMLMVAVIGFGVMVPIAGLLADAFGRRK
TMIVITLLMIAFAFLFPSMLGSGNQALVMGFLLCGLSIMGLTFGPMGALLPELFPTEVRYTGASFSYNVASILGAAVAPY
IATWLATHYGLFYVGLYLASMACLTLIALLLMKETRDQSL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789941, Length=441, Percent_Identity=83.2199546485261, Blast_Score=652, Evalue=0.0,
Organism=Escherichia coli, GI1788292, Length=436, Percent_Identity=36.0091743119266, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1790550, Length=428, Percent_Identity=33.6448598130841, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1788942, Length=399, Percent_Identity=33.3333333333333, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI87082404, Length=426, Percent_Identity=26.056338028169, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082231, Length=474, Percent_Identity=25.7383966244726, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004736
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1; PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 47165; Mature: 47165

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS00359 RIBOSOMAL_L11 ; PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQASIAPTLDADDAPTPVNSRGKVIVASLVGTAIEFFDFYIYATAAVIVFPHIFFPQGDP
CCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TTATLQSLATFAVAFVARPIGSALFGHFGDRVGRKVTLVASLLTMGISTVLIGLLPSYET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHH
IGIFAPILLALARFGQGLGLGGEWGGAALLATENAPPKKRALYGSFPQLGAPIGFFFANG
HHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCCCCCCCHHHHHHCH
TFLLLSWLLTDQQFMEWGWRVPFILSAALVLIGLYVRVSLHETPVFAKVAKAGKQVKIPL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEECCH
GTLLSKHLKATILGTFIMLATYTLFYLMTVYSMTYGTTAQPLGLGYSRNSFLWMLMVAVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
GFGVMVPIAGLLADAFGRRKTMIVITLLMIAFAFLFPSMLGSGNQALVMGFLLCGLSIMG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LTFGPMGALLPELFPTEVRYTGASFSYNVASILGAAVAPYIATWLATHYGLFYVGLYLAS
HCCCCHHHHHHHHCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MACLTLIALLLMKETRDQSL
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQASIAPTLDADDAPTPVNSRGKVIVASLVGTAIEFFDFYIYATAAVIVFPHIFFPQGDP
CCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TTATLQSLATFAVAFVARPIGSALFGHFGDRVGRKVTLVASLLTMGISTVLIGLLPSYET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHH
IGIFAPILLALARFGQGLGLGGEWGGAALLATENAPPKKRALYGSFPQLGAPIGFFFANG
HHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCCCCCCCHHHHHHCH
TFLLLSWLLTDQQFMEWGWRVPFILSAALVLIGLYVRVSLHETPVFAKVAKAGKQVKIPL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEECCH
GTLLSKHLKATILGTFIMLATYTLFYLMTVYSMTYGTTAQPLGLGYSRNSFLWMLMVAVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
GFGVMVPIAGLLADAFGRRKTMIVITLLMIAFAFLFPSMLGSGNQALVMGFLLCGLSIMG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LTFGPMGALLPELFPTEVRYTGASFSYNVASILGAAVAPYIATWLATHYGLFYVGLYLAS
HCCCCHHHHHHHHCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MACLTLIALLLMKETRDQSL
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]