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The map label for this gene is yfcS [H]

Identifier: 157372954

GI number: 157372954

Start: 5217000

End: 5217758

Strand: Reverse

Name: yfcS [H]

Synonym: Spro_4722

Alternate gene names: 157372954

Gene position: 5217758-5217000 (Counterclockwise)

Preceding gene: 157372955

Following gene: 157372953

Centisome position: 95.76

GC content: 61.0

Gene sequence:

>759_bases
ATGAAAACGCATTTTGTCATCAACAAACAGTGCCTGACCACCGCCACCCTGCTGGGCGCATTGTTGGCCCCGCAGGCGCA
GGCAGCGATAGCGCTGGACCGCACTCGGGTGATTTTTGACGGCGGCCAGAACTCGGTCAGCCTGAACATCAGCAACCAGA
ACAAACAGCTGCCGTACCTGGCGCAGGCTTGGCTGGAAGACGAGCAGGGCACCAAAATTCAGAGTCCGCTGGTGGTGCTG
CCACCGGTACAGCGCGTTGAGCCGGGCAAGCCGAGCCAGGTGAAAATCCAGGCGCTGTCGGCGGCCAAACAGCTGCCGCA
GGACCGCGAGACGCTGTACTACTTCAACCTGCGGGAAATCCCGCCGAAGAGCGACAAGCCGAACACCCTGCAGATAGCGT
TGCAGACGCGCATCAAGCTGTTCTACCGCCCGGCGGCGATCGCACCGCAGCAGAACGCAGCGCCCTGGCAGGAGAAGCTG
ACGCTGAGCAAGCAGGGCGACAAGTACCAGGTAAATAACCCGACGCCGTATTACATCACGATAGTCGATGCCAGCAGCAA
GAAAGGCGCGGAAGGGGTGAAGGGGTTTGAGCCGCTGATGGTGCCGCCAAAGGGCAATATATCGCTGGGCGTCAGCGCCA
CCGCGCTCGGTAGTAGCCCGGTGCTGACCTACATCAACGACTACGGCGGCCGTCCGCCGCTGACCTTTAACTGCAGCGGC
GGCAGTTGTCAGGTGGTGCCGGAGAAAGACAAGTCATAA

Upstream 100 bases:

>100_bases
GCTGAGCAACCTGCTGTTGCCGTGCCAGACGCTGCCGGCGGATGAGTCAGACGCAACCTAAGCGCAGACACCCTATTTGA
ATCAGCAAGAGAGATTTTTT

Downstream 100 bases:

>100_bases
AGCCGTAAGTCAGGGGCAGGTGAACAGGAGGAAAGGCTATGCAACGAATAAGCAAAAAATGGAGTCAACACCTGCCGGGT
TACCGCGACTGGCAGTACTA

Product: pili assembly chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MKTHFVINKQCLTTATLLGALLAPQAQAAIALDRTRVIFDGGQNSVSLNISNQNKQLPYLAQAWLEDEQGTKIQSPLVVL
PPVQRVEPGKPSQVKIQALSAAKQLPQDRETLYYFNLREIPPKSDKPNTLQIALQTRIKLFYRPAAIAPQQNAAPWQEKL
TLSKQGDKYQVNNPTPYYITIVDASSKKGAEGVKGFEPLMVPPKGNISLGVSATALGSSPVLTYINDYGGRPPLTFNCSG
GSCQVVPEKDKS

Sequences:

>Translated_252_residues
MKTHFVINKQCLTTATLLGALLAPQAQAAIALDRTRVIFDGGQNSVSLNISNQNKQLPYLAQAWLEDEQGTKIQSPLVVL
PPVQRVEPGKPSQVKIQALSAAKQLPQDRETLYYFNLREIPPKSDKPNTLQIALQTRIKLFYRPAAIAPQQNAAPWQEKL
TLSKQGDKYQVNNPTPYYITIVDASSKKGAEGVKGFEPLMVPPKGNISLGVSATALGSSPVLTYINDYGGRPPLTFNCSG
GSCQVVPEKDKS
>Mature_252_residues
MKTHFVINKQCLTTATLLGALLAPQAQAAIALDRTRVIFDGGQNSVSLNISNQNKQLPYLAQAWLEDEQGTKIQSPLVVL
PPVQRVEPGKPSQVKIQALSAAKQLPQDRETLYYFNLREIPPKSDKPNTLQIALQTRIKLFYRPAAIAPQQNAAPWQEKL
TLSKQGDKYQVNNPTPYYITIVDASSKKGAEGVKGFEPLMVPPKGNISLGVSATALGSSPVLTYINDYGGRPPLTFNCSG
GSCQVVPEKDKS

Specific function: Could be required for the biogenesis of a putative fimbria [H]

COG id: COG3121

COG function: function code NU; P pilus assembly protein, chaperone PapD

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1788677, Length=219, Percent_Identity=53.4246575342466, Blast_Score=254, Evalue=3e-69,
Organism=Escherichia coli, GI1786936, Length=217, Percent_Identity=43.3179723502304, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI87082203, Length=239, Percent_Identity=35.9832635983264, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1790771, Length=231, Percent_Identity=35.9307359307359, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1789532, Length=220, Percent_Identity=34.5454545454545, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787171, Length=241, Percent_Identity=32.7800829875519, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786333, Length=238, Percent_Identity=32.3529411764706, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788428, Length=223, Percent_Identity=32.7354260089686, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1786743, Length=237, Percent_Identity=28.6919831223629, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081806, Length=230, Percent_Identity=27.8260869565217, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 27456; Mature: 27456

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTHFVINKQCLTTATLLGALLAPQAQAAIALDRTRVIFDGGQNSVSLNISNQNKQLPYL
CCCEEEECHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEECCCCEEEEEECCCCCCCCHH
AQAWLEDEQGTKIQSPLVVLPPVQRVEPGKPSQVKIQALSAAKQLPQDRETLYYFNLREI
HHHHHCCCCCCEECCCEEEECCHHHCCCCCCCEEEEHHHHHHHHCCCCCCEEEEEEEECC
PPKSDKPNTLQIALQTRIKLFYRPAAIAPQQNAAPWQEKLTLSKQGDKYQVNNPTPYYIT
CCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCHHHHEEECCCCCEEECCCCCCEEEE
IVDASSKKGAEGVKGFEPLMVPPKGNISLGVSATALGSSPVLTYINDYGGRPPLTFNCSG
EEECCCCCCCCCCCCCCCEEECCCCCEEEEEEEEECCCCCEEEEECCCCCCCCEEEEECC
GSCQVVPEKDKS
CEEEEECCCCCC
>Mature Secondary Structure
MKTHFVINKQCLTTATLLGALLAPQAQAAIALDRTRVIFDGGQNSVSLNISNQNKQLPYL
CCCEEEECHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEECCCCEEEEEECCCCCCCCHH
AQAWLEDEQGTKIQSPLVVLPPVQRVEPGKPSQVKIQALSAAKQLPQDRETLYYFNLREI
HHHHHCCCCCCEECCCEEEECCHHHCCCCCCCEEEEHHHHHHHHCCCCCCEEEEEEEECC
PPKSDKPNTLQIALQTRIKLFYRPAAIAPQQNAAPWQEKLTLSKQGDKYQVNNPTPYYIT
CCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCHHHHEEECCCCCEEECCCCCCEEEE
IVDASSKKGAEGVKGFEPLMVPPKGNISLGVSATALGSSPVLTYINDYGGRPPLTFNCSG
EEECCCCCCCCCCCCCCCEEECCCCCEEEEEEEEECCCCCEEEEECCCCCCCCEEEEECC
GSCQVVPEKDKS
CEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]