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The map label for this gene is gntR [H]

Identifier: 157372884

GI number: 157372884

Start: 5139679

End: 5140710

Strand: Reverse

Name: gntR [H]

Synonym: Spro_4652

Alternate gene names: 157372884

Gene position: 5140710-5139679 (Counterclockwise)

Preceding gene: 157372885

Following gene: 157372883

Centisome position: 94.34

GC content: 56.98

Gene sequence:

>1032_bases
ATGAGCGCCCATTCACGGTTAGCCAGTTCATTGATAATGAAGAAAAAACGGCCGGTACTCCAAGATGTTGCAGACAAGGT
TGGCGTAACCAAGATGACGGTGAGCCGTTATCTGCGTAATCCCGATCAGGTTTCTGCCGTCTTGCAGCAAAAAATTGCCG
TCGCGCTTGATGAGCTGGGCTACATTCCCAACCGTGCGCCGGATATCCTTTCCAACTCCACCAGCCGCGCCATTGGCGTC
CTGCTGCCGTCGCTGACCAACCAGGTGTTTGCCGAAGTATTGCGCGGCATCGAGAGCGTCACCGATGCGCACAATTACCA
GACCATGCTGGCGCACTACGGCTATTTGCCGGAGCGTGAAGAACAGCGCCTGACCTCGTTGCTGTCTTACAATATTGATG
GGTTGATCCTGTCTGAACGTCACCATACGCCACGTACCATGAAAATGATCGAGGTTGCGGGTATCCCGGTCGTCGAGCTG
ATGGACTGCGTTTCGCCCTGTATCGATCTGGCGGTAGGTTTCAATAACTTTGAGGCCGCACGCCAGATGACCCAGCAAAT
CATCGCGCACGGCCATCGCCACGTGGTGTATTTCGGCGCGCGTCAGGATGAACGTACCATTATCAAACAGCAGGGCTATG
AACAGGCGATGCGTGAATCCGGTCTGCAGCCTTACAGCGTGATGACGGCGCGTTCGTCTTCTTATTCCGCCGGTGGTGAA
CTGCTGCGTCAGGCGCAACGCGACTACCCGCAGATTGACAGTATTTTCTGCACCAACGATGACCTGGCAATAGGGGCTAC
CTTCGAGTGCCAGCGGCAGGGGCTGTCGATCCCCAACGATATGGCGATTGCCGGTTTCCACGGCCACGATATCGGTCAGG
TGATGGTGCCGAAGCTGGCCAGCGTGTTGACGCCGCGTGAACGCATGGGGCAAATCGGCGCCGAACGCCTGTTGGCCCGA
CTGCGGGGTGAAACGGTCAGCCCGCGCATGGTGGACGTTGGTTTCACCGTGATCCCCGGTGGCAGTATCTGA

Upstream 100 bases:

>100_bases
TCTGATTAAGCGGTAAATATCAAGGGCTCACGCGGTGGGCCCTTTTTGCGTCATACCTTCCAACAACCAACAATATCGGC
CCCGGTTTTTTTTTGCTAAA

Downstream 100 bases:

>100_bases
TCGGTTTTAAGCCATTTTAATTCTGGAACCGCGCTGCTTGGCGCGTTTTCATTTCCCTCTGTAAGCCTGCCCCCTGTTAC
CCCCATAAGTTTGATCTCTA

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSAHSRLASSLIMKKKRPVLQDVADKVGVTKMTVSRYLRNPDQVSAVLQQKIAVALDELGYIPNRAPDILSNSTSRAIGV
LLPSLTNQVFAEVLRGIESVTDAHNYQTMLAHYGYLPEREEQRLTSLLSYNIDGLILSERHHTPRTMKMIEVAGIPVVEL
MDCVSPCIDLAVGFNNFEAARQMTQQIIAHGHRHVVYFGARQDERTIIKQQGYEQAMRESGLQPYSVMTARSSSYSAGGE
LLRQAQRDYPQIDSIFCTNDDLAIGATFECQRQGLSIPNDMAIAGFHGHDIGQVMVPKLASVLTPRERMGQIGAERLLAR
LRGETVSPRMVDVGFTVIPGGSI

Sequences:

>Translated_343_residues
MSAHSRLASSLIMKKKRPVLQDVADKVGVTKMTVSRYLRNPDQVSAVLQQKIAVALDELGYIPNRAPDILSNSTSRAIGV
LLPSLTNQVFAEVLRGIESVTDAHNYQTMLAHYGYLPEREEQRLTSLLSYNIDGLILSERHHTPRTMKMIEVAGIPVVEL
MDCVSPCIDLAVGFNNFEAARQMTQQIIAHGHRHVVYFGARQDERTIIKQQGYEQAMRESGLQPYSVMTARSSSYSAGGE
LLRQAQRDYPQIDSIFCTNDDLAIGATFECQRQGLSIPNDMAIAGFHGHDIGQVMVPKLASVLTPRERMGQIGAERLLAR
LRGETVSPRMVDVGFTVIPGGSI
>Mature_342_residues
SAHSRLASSLIMKKKRPVLQDVADKVGVTKMTVSRYLRNPDQVSAVLQQKIAVALDELGYIPNRAPDILSNSTSRAIGVL
LPSLTNQVFAEVLRGIESVTDAHNYQTMLAHYGYLPEREEQRLTSLLSYNIDGLILSERHHTPRTMKMIEVAGIPVVELM
DCVSPCIDLAVGFNNFEAARQMTQQIIAHGHRHVVYFGARQDERTIIKQQGYEQAMRESGLQPYSVMTARSSSYSAGGEL
LRQAQRDYPQIDSIFCTNDDLAIGATFECQRQGLSIPNDMAIAGFHGHDIGQVMVPKLASVLTPRERMGQIGAERLLARL
RGETVSPRMVDVGFTVIPGGSI

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=331, Percent_Identity=80.3625377643504, Blast_Score=570, Evalue=1e-164,
Organism=Escherichia coli, GI1790715, Length=332, Percent_Identity=44.8795180722892, Blast_Score=304, Evalue=5e-84,
Organism=Escherichia coli, GI1790369, Length=336, Percent_Identity=29.1666666666667, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788474, Length=318, Percent_Identity=25.1572327044025, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790194, Length=313, Percent_Identity=25.2396166134185, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787906, Length=270, Percent_Identity=26.2962962962963, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1787948, Length=323, Percent_Identity=24.7678018575851, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789068, Length=320, Percent_Identity=25.625, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786540, Length=318, Percent_Identity=25.4716981132075, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789202, Length=298, Percent_Identity=23.8255033557047, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1787580, Length=331, Percent_Identity=23.8670694864048, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790689, Length=323, Percent_Identity=20.1238390092879, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1786268, Length=330, Percent_Identity=23.3333333333333, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37920; Mature: 37789

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAHSRLASSLIMKKKRPVLQDVADKVGVTKMTVSRYLRNPDQVSAVLQQKIAVALDELG
CCHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
YIPNRAPDILSNSTSRAIGVLLPSLTNQVFAEVLRGIESVTDAHNYQTMLAHYGYLPERE
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
EQRLTSLLSYNIDGLILSERHHTPRTMKMIEVAGIPVVELMDCVSPCIDLAVGFNNFEAA
HHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHH
RQMTQQIIAHGHRHVVYFGARQDERTIIKQQGYEQAMRESGLQPYSVMTARSSSYSAGGE
HHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCHHHHHHHCCCCCCCCEEECCCCCCHHHH
LLRQAQRDYPQIDSIFCTNDDLAIGATFECQRQGLSIPNDMAIAGFHGHDIGQVMVPKLA
HHHHHHHCCCCCCCEEECCCCEEECCCHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHH
SVLTPRERMGQIGAERLLARLRGETVSPRMVDVGFTVIPGGSI
HHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEECCCCCC
>Mature Secondary Structure 
SAHSRLASSLIMKKKRPVLQDVADKVGVTKMTVSRYLRNPDQVSAVLQQKIAVALDELG
CHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
YIPNRAPDILSNSTSRAIGVLLPSLTNQVFAEVLRGIESVTDAHNYQTMLAHYGYLPERE
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
EQRLTSLLSYNIDGLILSERHHTPRTMKMIEVAGIPVVELMDCVSPCIDLAVGFNNFEAA
HHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHH
RQMTQQIIAHGHRHVVYFGARQDERTIIKQQGYEQAMRESGLQPYSVMTARSSSYSAGGE
HHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCHHHHHHHCCCCCCCCEEECCCCCCHHHH
LLRQAQRDYPQIDSIFCTNDDLAIGATFECQRQGLSIPNDMAIAGFHGHDIGQVMVPKLA
HHHHHHHCCCCCCCEEECCCCEEECCCHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHH
SVLTPRERMGQIGAERLLARLRGETVSPRMVDVGFTVIPGGSI
HHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]