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The map label for this gene is gntT [H]

Identifier: 157372883

GI number: 157372883

Start: 5138033

End: 5139349

Strand: Reverse

Name: gntT [H]

Synonym: Spro_4651

Alternate gene names: 157372883

Gene position: 5139349-5138033 (Counterclockwise)

Preceding gene: 157372884

Following gene: 157372882

Centisome position: 94.32

GC content: 57.48

Gene sequence:

>1317_bases
ATGCCATTAGTGATTGTTGCAGGCGGCGTAGCGCTGCTGCTGCTGCTGATGATTCGCTTTAAGCTGAACGGTTTTATCTC
TTTGATTCTGGTTGCTCTGGCGGTCGGGATCACCCAGGGGATGCCGGTCGATAAAGTGATCGGCTCCATCAAGGCCGGCG
TTGGCGGCACGCTGGGCAGTCTGGCGTTGATCATGGGTTTTGGTGCCATGCTCGGCAAGCTGCTGGCGGACTGCGGCGGT
GCCCAGCGCATCGCCACTACGCTTATAGAAAAGTTCGGTAAAAAACACATTCAGTGGGCAGTGGTGCTGACGGGCTTTAC
CGTCGGCTTCGCGCTGTTCTATGAGGTGGGTTTCGTGCTGTTGCTGCCGCTGGTATTCAGTATCGCCGCTTCCGCGCGCG
TTCCTCTGCTGTATGTCGGTGTGCCAATGGCGGCTGCGCTGTCGGTAACCCACGGTTTCCTGCCGCCGCACCCTGGCCCA
ACGGCGATCGCCACCATCTTCCATGCCGATATGGGTAAAACCCTGCTGTACGGTACGCTGCTGGCTATCCCGACGGTGAT
CCTGGCCGGTCCGGTTTATGCCCGCTTCCTGAAAGGTATCGACAAGCCGGTACCGGAAGGCCTGTATAACCCAAAAATCT
TCACCGAAGCGGAAATGCCAAGCTTTGGTATCAGCGTGGCAACCTCTCTGGTGCCGGTGATCCTGATGGCGTTGCGCGCG
GTAGCCGAAATGGTGCTGCCGAAGGGTCATAGCCTGTTGCGCTTTGCCGAGTTCTTCGGTGATCCGGTAATGGCGACGCT
GATTGCGGTGCTGATTGCTATCTTCACCTTTGGCCTGAACCGTGGCCGCACCATGGATGAAGTGATGGGCACCATCACCG
ACTCCATCAAGATTATCGCCATGATGCTGTTGATCATCGGCGGTGGCGGTGCGTTCAAGCAGGTGCTGGTCGACAGCGGC
GTAGAGAAATATATTGCCGCCCTGATGGAAGGCAGTAACGTCTCGCCGATCCTGCTGGCATGGTCGATTGCCGCCGCACT
GCGTTTGGCACTGGGTTCGGCTACCGTGGCGGCGATTACCGCCGGGGGTATTGTTGCTCCGCTGATCGCCACTACCGGCG
CCAGTCCGGAACTGATGGTGATCGCAGTCGGTTCAGGCAGCGTGATTTTCTCTCACGTCAATGACCCGGGTTTCTGGCTG
TTCAAGGAGTACTTCAACCTGAGCATCATGGAAACCATTAAATCCTGGTCGGTGCTGGAAACCATCATTTCAGTCTGTGG
TTTGGTAGGTTGCCTACTGCTGGCGACGGTCGTCTAA

Upstream 100 bases:

>100_bases
AGCTCGTCTTCTAACACCGGGAAGAGCCTAAAAATACAACAAACGCGCGCTTTACGGCCTATCGTAAAGAGGTCTGCGAT
AAAAAGGTTGGAGAAAAATT

Downstream 100 bases:

>100_bases
AATACTGAGGTTTCCGGCACCTTGGCGGTGTCGGAAACTATTTTGAGTTTGGGGCGCATTTGATGACGCTGCCAGCGTCA
TCTGATCCCATAAGGGCATG

Product: gluconate transporter

Products: Proton [Cytoplasm]; gluconate [Cytoplasm] [C]

Alternate protein names: Gluconate permease; Gnt-I system [H]

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MPLVIVAGGVALLLLLMIRFKLNGFISLILVALAVGITQGMPVDKVIGSIKAGVGGTLGSLALIMGFGAMLGKLLADCGG
AQRIATTLIEKFGKKHIQWAVVLTGFTVGFALFYEVGFVLLLPLVFSIAASARVPLLYVGVPMAAALSVTHGFLPPHPGP
TAIATIFHADMGKTLLYGTLLAIPTVILAGPVYARFLKGIDKPVPEGLYNPKIFTEAEMPSFGISVATSLVPVILMALRA
VAEMVLPKGHSLLRFAEFFGDPVMATLIAVLIAIFTFGLNRGRTMDEVMGTITDSIKIIAMMLLIIGGGGAFKQVLVDSG
VEKYIAALMEGSNVSPILLAWSIAAALRLALGSATVAAITAGGIVAPLIATTGASPELMVIAVGSGSVIFSHVNDPGFWL
FKEYFNLSIMETIKSWSVLETIISVCGLVGCLLLATVV

Sequences:

>Translated_438_residues
MPLVIVAGGVALLLLLMIRFKLNGFISLILVALAVGITQGMPVDKVIGSIKAGVGGTLGSLALIMGFGAMLGKLLADCGG
AQRIATTLIEKFGKKHIQWAVVLTGFTVGFALFYEVGFVLLLPLVFSIAASARVPLLYVGVPMAAALSVTHGFLPPHPGP
TAIATIFHADMGKTLLYGTLLAIPTVILAGPVYARFLKGIDKPVPEGLYNPKIFTEAEMPSFGISVATSLVPVILMALRA
VAEMVLPKGHSLLRFAEFFGDPVMATLIAVLIAIFTFGLNRGRTMDEVMGTITDSIKIIAMMLLIIGGGGAFKQVLVDSG
VEKYIAALMEGSNVSPILLAWSIAAALRLALGSATVAAITAGGIVAPLIATTGASPELMVIAVGSGSVIFSHVNDPGFWL
FKEYFNLSIMETIKSWSVLETIISVCGLVGCLLLATVV
>Mature_437_residues
PLVIVAGGVALLLLLMIRFKLNGFISLILVALAVGITQGMPVDKVIGSIKAGVGGTLGSLALIMGFGAMLGKLLADCGGA
QRIATTLIEKFGKKHIQWAVVLTGFTVGFALFYEVGFVLLLPLVFSIAASARVPLLYVGVPMAAALSVTHGFLPPHPGPT
AIATIFHADMGKTLLYGTLLAIPTVILAGPVYARFLKGIDKPVPEGLYNPKIFTEAEMPSFGISVATSLVPVILMALRAV
AEMVLPKGHSLLRFAEFFGDPVMATLIAVLIAIFTFGLNRGRTMDEVMGTITDSIKIIAMMLLIIGGGGAFKQVLVDSGV
EKYIAALMEGSNVSPILLAWSIAAALRLALGSATVAAITAGGIVAPLIATTGASPELMVIAVGSGSVIFSHVNDPGFWLF
KEYFNLSIMETIKSWSVLETIISVCGLVGCLLLATVV

Specific function: Part of the gluconate utilization system Gnt-I; high- affinity intake of gluconate [H]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=438, Percent_Identity=85.8447488584475, Blast_Score=734, Evalue=0.0,
Organism=Escherichia coli, GI1790716, Length=438, Percent_Identity=62.1004566210046, Blast_Score=548, Evalue=1e-157,
Organism=Escherichia coli, GI2367370, Length=449, Percent_Identity=49.8886414253898, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1790776, Length=435, Percent_Identity=40.2298850574713, Blast_Score=343, Evalue=1e-95,
Organism=Escherichia coli, GI1788707, Length=433, Percent_Identity=36.9515011547344, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI48994939, Length=426, Percent_Identity=36.3849765258216, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1789097, Length=440, Percent_Identity=33.4090909090909, Blast_Score=217, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 45680; Mature: 45549

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVIVAGGVALLLLLMIRFKLNGFISLILVALAVGITQGMPVDKVIGSIKAGVGGTLGS
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHH
LALIMGFGAMLGKLLADCGGAQRIATTLIEKFGKKHIQWAVVLTGFTVGFALFYEVGFVL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLPLVFSIAASARVPLLYVGVPMAAALSVTHGFLPPHPGPTAIATIFHADMGKTLLYGTL
HHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHH
LAIPTVILAGPVYARFLKGIDKPVPEGLYNPKIFTEAEMPSFGISVATSLVPVILMALRA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHH
VAEMVLPKGHSLLRFAEFFGDPVMATLIAVLIAIFTFGLNRGRTMDEVMGTITDSIKIIA
HHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
MMLLIIGGGGAFKQVLVDSGVEKYIAALMEGSNVSPILLAWSIAAALRLALGSATVAAIT
HHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
AGGIVAPLIATTGASPELMVIAVGSGSVIFSHVNDPGFWLFKEYFNLSIMETIKSWSVLE
HCHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHCHHHHHHHHHHHHHH
TIISVCGLVGCLLLATVV
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PLVIVAGGVALLLLLMIRFKLNGFISLILVALAVGITQGMPVDKVIGSIKAGVGGTLGS
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHH
LALIMGFGAMLGKLLADCGGAQRIATTLIEKFGKKHIQWAVVLTGFTVGFALFYEVGFVL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLPLVFSIAASARVPLLYVGVPMAAALSVTHGFLPPHPGPTAIATIFHADMGKTLLYGTL
HHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHH
LAIPTVILAGPVYARFLKGIDKPVPEGLYNPKIFTEAEMPSFGISVATSLVPVILMALRA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHH
VAEMVLPKGHSLLRFAEFFGDPVMATLIAVLIAIFTFGLNRGRTMDEVMGTITDSIKIIA
HHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
MMLLIIGGGGAFKQVLVDSGVEKYIAALMEGSNVSPILLAWSIAAALRLALGSATVAAIT
HHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
AGGIVAPLIATTGASPELMVIAVGSGSVIFSHVNDPGFWLFKEYFNLSIMETIKSWSVLE
HCHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHCHHHHHHHHHHHHHH
TIISVCGLVGCLLLATVV
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 2845225; 7984428; 3040894; 9045817 [H]