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The map label for this gene is tsgA

Identifier: 157372825

GI number: 157372825

Start: 5066484

End: 5067668

Strand: Direct

Name: tsgA

Synonym: Spro_4593

Alternate gene names: 157372825

Gene position: 5066484-5067668 (Clockwise)

Preceding gene: 157372824

Following gene: 157372827

Centisome position: 92.98

GC content: 55.11

Gene sequence:

>1185_bases
ATGAATGATAGCAACCGTCTACGGCTTACCTGGATCAGCTACTTTTCTTACGCGCTGACCGGTGCTTTAGTTATCGTCAC
AGGGATGGTGATGGGGAACATTGCAGAGTACTTTAATCTGCCGGTTTCCAGCATGAGCAATACTTTCACCTTCCTTAACG
CCGGTATTTTGATTTCGATCTTCCTCAATGCCTGGCTGATGGAAATTATCCCGCTTAAACGTCAACTGATGTTTGGCTTT
GTGCTGATGGTACTGGCTATTGCCGGGCTGATGCTCGGTAAAAGCCTGACCATGTTCTCGTTGTGCATGTTTATCCTTGG
CGTGGTCAGCGGTATCACCATGTCGATAGGCACCTTCCTGATCACCCATATGTATGCCGGCCGCCAACGCGGTTCGCGCC
TGCTGTTCACTGACTCCTTCTTCAGCATGGCCGGAATGATCTTCCCGATTGTCGCCGCGATGCTGTTGGCGCGTCAGATC
GGCTGGTACTGGGTGTACGCCTGCATCGGCCTGCTGTATGTAGGTATCTTTGTGCTGACCCTGTTCTCCGAGTTCCCGGT
ACTGGGCAACAAAGGAGCCGACGCGGGCCAGCCGGTAGTGAAAGAGAAATGGGGTATCGGCGTGCTGTTCCTGTCGATCG
CCGCACTGTGCTACATCCTCGGCCAGCTTGGCTTCATTCAGTGGGTGCCGGAATACGCCACCAAGTCGTTCGGGATGGAT
ATCAGCCAGGCCGGTAAGCTGGTGAGCGATTTCTGGACCTCGTACATGATCGGCATGTGGGTATTCAGCTTTATCCTGCG
CTTCTTCGATTTGCAGCGCATCGTCACTATCCTGGCCGCATTGGCGACCGGTGCGATGTACCTGTTCGTCAGCACCGATA
ACCCGGAACACCTGAGCTACTACATTATGGCTCTGGGCTTCGTTTCCAGCGCGATCTACACCACCCTGATCACTCTGGGC
TCGCTGCAGACCAAGGTTTCCTCACCGAAACTGGTTAACTTCATCCTGACCTGCGGCACCATCGGCACCATGCTGACCTT
CGTGGTTACCGGCCCGATCGTAGCCAAAGGCGGCGCACACGCGGCGCTGACTACCGCCAATGGTCTGTACCTGGCGGTGT
TCGTGATGTGTCTGCTGCTCGGTTTCGTAACCAAGCACCGCAGCCACGGTCACGTGACCCACTGA

Upstream 100 bases:

>100_bases
CCCTGGTGGCCTGATCGGGACTTTTTTCTGCATTTGCCAGGAAAAGCCAGCGGCCTTATGCCAGTTTTAAACTCTTTATA
GACTTAATCAGGCCTAAATA

Downstream 100 bases:

>100_bases
TCTGTCGTCAATGACGTGATATGAAAAGGGCGCCTCGGCGCCCTTTTTTATGCTGATAACCCCCAGCTCAACGCCGGAAA
TCCACCTTCTCATCCTGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MNDSNRLRLTWISYFSYALTGALVIVTGMVMGNIAEYFNLPVSSMSNTFTFLNAGILISIFLNAWLMEIIPLKRQLMFGF
VLMVLAIAGLMLGKSLTMFSLCMFILGVVSGITMSIGTFLITHMYAGRQRGSRLLFTDSFFSMAGMIFPIVAAMLLARQI
GWYWVYACIGLLYVGIFVLTLFSEFPVLGNKGADAGQPVVKEKWGIGVLFLSIAALCYILGQLGFIQWVPEYATKSFGMD
ISQAGKLVSDFWTSYMIGMWVFSFILRFFDLQRIVTILAALATGAMYLFVSTDNPEHLSYYIMALGFVSSAIYTTLITLG
SLQTKVSSPKLVNFILTCGTIGTMLTFVVTGPIVAKGGAHAALTTANGLYLAVFVMCLLLGFVTKHRSHGHVTH

Sequences:

>Translated_394_residues
MNDSNRLRLTWISYFSYALTGALVIVTGMVMGNIAEYFNLPVSSMSNTFTFLNAGILISIFLNAWLMEIIPLKRQLMFGF
VLMVLAIAGLMLGKSLTMFSLCMFILGVVSGITMSIGTFLITHMYAGRQRGSRLLFTDSFFSMAGMIFPIVAAMLLARQI
GWYWVYACIGLLYVGIFVLTLFSEFPVLGNKGADAGQPVVKEKWGIGVLFLSIAALCYILGQLGFIQWVPEYATKSFGMD
ISQAGKLVSDFWTSYMIGMWVFSFILRFFDLQRIVTILAALATGAMYLFVSTDNPEHLSYYIMALGFVSSAIYTTLITLG
SLQTKVSSPKLVNFILTCGTIGTMLTFVVTGPIVAKGGAHAALTTANGLYLAVFVMCLLLGFVTKHRSHGHVTH
>Mature_394_residues
MNDSNRLRLTWISYFSYALTGALVIVTGMVMGNIAEYFNLPVSSMSNTFTFLNAGILISIFLNAWLMEIIPLKRQLMFGF
VLMVLAIAGLMLGKSLTMFSLCMFILGVVSGITMSIGTFLITHMYAGRQRGSRLLFTDSFFSMAGMIFPIVAAMLLARQI
GWYWVYACIGLLYVGIFVLTLFSEFPVLGNKGADAGQPVVKEKWGIGVLFLSIAALCYILGQLGFIQWVPEYATKSFGMD
ISQAGKLVSDFWTSYMIGMWVFSFILRFFDLQRIVTILAALATGAMYLFVSTDNPEHLSYYIMALGFVSSAIYTTLITLG
SLQTKVSSPKLVNFILTCGTIGTMLTFVVTGPIVAKGGAHAALTTANGLYLAVFVMCLLLGFVTKHRSHGHVTH

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TsgA family

Homologues:

Organism=Escherichia coli, GI1789764, Length=393, Percent_Identity=76.0814249363868, Blast_Score=601, Evalue=1e-173,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TSGA_SERP5 (A8GKP6)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001480814.1
- ProteinModelPortal:   A8GKP6
- STRING:   A8GKP6
- GeneID:   5607101
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_4593
- eggNOG:   COG0477
- HOGENOM:   HBG366226
- OMA:   TIDANKP
- ProtClustDB:   PRK03699
- BioCyc:   SPRO399741:SPRO_4593-MONOMER
- HAMAP:   MF_01044
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 43291; Mature: 43291

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11c0dac8)-; HASH(0x11cfce40)-; HASH(0xbc738c0)-; HASH(0x40af4c84)-; HASH(0x10af3750)-; HASH(0x1168ab08)-; HASH(0x11bccd38)-; HASH(0x115322ac)-; HASH(0x1101bc38)-; HASH(0x11e2bb04)-; HASH(0x12282270)-; HASH(0x11cc4348)-;

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCH
>Mature Secondary Structure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EEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA