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The map label for this gene is pabA [H]

Identifier: 157372815

GI number: 157372815

Start: 5057070

End: 5057645

Strand: Reverse

Name: pabA [H]

Synonym: Spro_4583

Alternate gene names: 157372815

Gene position: 5057645-5057070 (Counterclockwise)

Preceding gene: 157372816

Following gene: 157372814

Centisome position: 92.82

GC content: 57.99

Gene sequence:

>576_bases
ATGCTGCTGCTAATCGATAACTACGATTCTTTTACCTATAACCTTTACCAGTACTTCTGCCAATTAGGCGCCGAAGTGCT
GGTGAAGCGTAACGACGAACTGCAACTGGCCGATATCGAAAGGCTGGCCCCGCAGCATTTGGTGATCTCTCCTGGCCCTT
GCACCCCGAACGAAGCCGGTATCTCGCTGGCGGCCATTAGGCATTTTGCCGGCAGGCTGCCGATCCTCGGTGTTTGCCTG
GGGCACCAGGCACTGGGGCAGGCTTTTGGCGCCAAGGTCGTGCGTGCCCGCGAGGTGATGCACGGCAAAACCTCGGCGAT
CCGCCATCTCGACAGTGGCGTTTTTCATGGACTGAACAACCCGCTGACCGTGACCCGCTACCACTCGCTGGTGCTTGAAG
CCGCTACTTTGCCGGACTGTTTTGAAGTGACGGCCTGGAGCGAGCGCGACGGCGTACGCGATGAGATTATGGGGATCCGC
CACCGCCAACTGGCGCTGGAAGGGGTGCAGTTCCACCCGGAGAGCATCCTTAGCGAGCAGGGGCACCAGCTGTTGGATAA
TTTCCTTAAAAGTTAA

Upstream 100 bases:

>100_bases
AAGCTGAAATTATCGCTGGCGGCAGCATTGCAGGGGCGTTGTATAATGCACCGGTATCAATCGGGGCGAGCCCCTTACCC
TGCTGTCCGTTGGAACCCCT

Downstream 100 bases:

>100_bases
TCGGTTAGGTTTTTTTTAACCGTGAAGACGATTTGCGTTTGCCCTTTATTGGTTTTTTATGCATATTTTGTGATTATATT
TTCACTCAATTGCAACCAAA

Product: para-aminobenzoate synthase component II

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MLLLIDNYDSFTYNLYQYFCQLGAEVLVKRNDELQLADIERLAPQHLVISPGPCTPNEAGISLAAIRHFAGRLPILGVCL
GHQALGQAFGAKVVRAREVMHGKTSAIRHLDSGVFHGLNNPLTVTRYHSLVLEAATLPDCFEVTAWSERDGVRDEIMGIR
HRQLALEGVQFHPESILSEQGHQLLDNFLKS

Sequences:

>Translated_191_residues
MLLLIDNYDSFTYNLYQYFCQLGAEVLVKRNDELQLADIERLAPQHLVISPGPCTPNEAGISLAAIRHFAGRLPILGVCL
GHQALGQAFGAKVVRAREVMHGKTSAIRHLDSGVFHGLNNPLTVTRYHSLVLEAATLPDCFEVTAWSERDGVRDEIMGIR
HRQLALEGVQFHPESILSEQGHQLLDNFLKS
>Mature_191_residues
MLLLIDNYDSFTYNLYQYFCQLGAEVLVKRNDELQLADIERLAPQHLVISPGPCTPNEAGISLAAIRHFAGRLPILGVCL
GHQALGQAFGAKVVRAREVMHGKTSAIRHLDSGVFHGLNNPLTVTRYHSLVLEAATLPDCFEVTAWSERDGVRDEIMGIR
HRQLALEGVQFHPESILSEQGHQLLDNFLKS

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=189, Percent_Identity=77.7777777777778, Blast_Score=302, Evalue=1e-83,
Organism=Escherichia coli, GI1787517, Length=191, Percent_Identity=43.455497382199, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786215, Length=155, Percent_Identity=29.0322580645161, Blast_Score=65, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=189, Percent_Identity=49.2063492063492, Blast_Score=200, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=30.8056872037915, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 21252; Mature: 21252

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLIDNYDSFTYNLYQYFCQLGAEVLVKRNDELQLADIERLAPQHLVISPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCCEEEECCCCCCCCCC
ISLAAIRHFAGRLPILGVCLGHQALGQAFGAKVVRAREVMHGKTSAIRHLDSGVFHGLNN
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCC
PLTVTRYHSLVLEAATLPDCFEVTAWSERDGVRDEIMGIRHRQLALEGVQFHPESILSEQ
CEEHHHHHHHHHHHCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
GHQLLDNFLKS
HHHHHHHHHCC
>Mature Secondary Structure
MLLLIDNYDSFTYNLYQYFCQLGAEVLVKRNDELQLADIERLAPQHLVISPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCCEEEECCCCCCCCCC
ISLAAIRHFAGRLPILGVCLGHQALGQAFGAKVVRAREVMHGKTSAIRHLDSGVFHGLNN
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCC
PLTVTRYHSLVLEAATLPDCFEVTAWSERDGVRDEIMGIRHRQLALEGVQFHPESILSEQ
CEEHHHHHHHHHHHCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
GHQLLDNFLKS
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3894673 [H]