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The map label for this gene is degQ [H]

Identifier: 157372585

GI number: 157372585

Start: 4823910

End: 4825280

Strand: Direct

Name: degQ [H]

Synonym: Spro_4352

Alternate gene names: 157372585

Gene position: 4823910-4825280 (Clockwise)

Preceding gene: 157372584

Following gene: 157372586

Centisome position: 88.53

GC content: 57.4

Gene sequence:

>1371_bases
ATGAATAAAAAGTCGTTAATTCTTAGTGCATTGGCAATGAGTATTGGCATCACACTGACCTCCGTACCGGCAGCCAACGC
GGCGATGCCTGTCGCCGTGCAGGGGCAGCAGTTGCCAAGCCTGGCGCCGATGTTGGAAAAAGTATTGCCCGCTGTCGTCA
GCGTGCATGTGGAAGGCACTCAGGTGCAGCGCCAGCAGGTACCGGAAGAGCTCAAACGCTTCTTCGGCCCCGACGCGCCA
GGACAACAGCAAAGCTCACGCCCGTTTGAAGGCTTGGGTTCTGGCGTGATCATCGACGCCGCCAAGGGCTATGTGTTGAC
CAACAACCACGTGATCAACAATGCCGACAAAATCAGCGTACAGTTGAATGACGGGCGTGAAGTGGATGCCAAGTTGTTGG
GACGTGACGAACAGTCCGACATTGCCCTGCTGCAGCTCAGCGATGTGAAAAACCTGACCGCGATAAAAATGGCGGACTCC
GATCAACTGCGGGTCGGCGACTTTGCCGTGGCCGTCGGCAACCCATTCGGCCTCGGCCAGACGGCGACCTCCGGTATTAT
CTCTGCGCTGGGTCGTAGCGGTCTGAACCTGGAAGGGTTGGAAAACTTCATTCAGACCGATGCTTCCATCAACCGCGGTA
ACTCCGGTGGCGCACTGGTTAACCTCAACGGTGAGTTAATCGGTATCAACACCGCCATTTTGGCGCCAAGCGGCGGCAAC
GTGGGCATCGGCTTTGCCATTCCGAGCAACATGGCGCAGAACCTCAGCCAGCAGTTGATTGAATTTGGCGAAGTGAAACG
CGGCCTGCTGGGCATCAAAGGCAGTGAAATGACCGCCGATATGGCCAAGGCGTTTAACACCGACGCCCAACGCGGTGCCT
TCGTCAGCGAAGTGTTGCCGAAATCTGCCGCCGCCAAGGCCGGCATCAAAGCCGGTGACATTCTGGTTTCCGTCGACGGC
AAGCCCGTCAGCAGCTTCGCCGAACTGCGTGCCAAGGTCGGTACCACCGCGCCGGGCAAAACCATCAAGGTTGGCTTGCT
GCGCGACGGTAAGCCACTGGAAGTTTCCGTCACCCTGGATAACAGTGAAGGCGCCTCCACCAACGCCGAAACGCTTTCTC
CGGCTCTGCAGGGCGTGTCACTGAGCAACGGTGCCATTCCAAGTGGTGACAAAGGCGTGAAGATCGATAGAGTCGATAAA
GGCTCCGTAGCCGCGCAGATCGGGTTGCAGAAGGACGATGTGATCATTGGCGTCAACCGTCAGCGCGTTGAAAACATCAC
GACCTTACGCAAGGTGCTGGAAGCCAAGCCACCGGTGATGGCACTGAACATCGTGCGCGGCGGCGAAACCATTTATCTGC
TGTTGCGTTAA

Upstream 100 bases:

>100_bases
TGAACTTTTCACGCAAATTCACGGTCTTACCCTTCACTATGGTAGTGCTGCTGCATTATCATCACCCTTTCACCGGCAGG
TATTGAGAGAGTTATAATCA

Downstream 100 bases:

>100_bases
TCGGTAATTTGTTTAAAAACCGGGCCCGGTGACATACTGCGCCCGGTATTCTCATGCTATCCTCCGTGTATCTTTCATCT
CACGTACTAAAACTCCATGT

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MNKKSLILSALAMSIGITLTSVPAANAAMPVAVQGQQLPSLAPMLEKVLPAVVSVHVEGTQVQRQQVPEELKRFFGPDAP
GQQQSSRPFEGLGSGVIIDAAKGYVLTNNHVINNADKISVQLNDGREVDAKLLGRDEQSDIALLQLSDVKNLTAIKMADS
DQLRVGDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALVNLNGELIGINTAILAPSGGN
VGIGFAIPSNMAQNLSQQLIEFGEVKRGLLGIKGSEMTADMAKAFNTDAQRGAFVSEVLPKSAAAKAGIKAGDILVSVDG
KPVSSFAELRAKVGTTAPGKTIKVGLLRDGKPLEVSVTLDNSEGASTNAETLSPALQGVSLSNGAIPSGDKGVKIDRVDK
GSVAAQIGLQKDDVIIGVNRQRVENITTLRKVLEAKPPVMALNIVRGGETIYLLLR

Sequences:

>Translated_456_residues
MNKKSLILSALAMSIGITLTSVPAANAAMPVAVQGQQLPSLAPMLEKVLPAVVSVHVEGTQVQRQQVPEELKRFFGPDAP
GQQQSSRPFEGLGSGVIIDAAKGYVLTNNHVINNADKISVQLNDGREVDAKLLGRDEQSDIALLQLSDVKNLTAIKMADS
DQLRVGDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALVNLNGELIGINTAILAPSGGN
VGIGFAIPSNMAQNLSQQLIEFGEVKRGLLGIKGSEMTADMAKAFNTDAQRGAFVSEVLPKSAAAKAGIKAGDILVSVDG
KPVSSFAELRAKVGTTAPGKTIKVGLLRDGKPLEVSVTLDNSEGASTNAETLSPALQGVSLSNGAIPSGDKGVKIDRVDK
GSVAAQIGLQKDDVIIGVNRQRVENITTLRKVLEAKPPVMALNIVRGGETIYLLLR
>Mature_456_residues
MNKKSLILSALAMSIGITLTSVPAANAAMPVAVQGQQLPSLAPMLEKVLPAVVSVHVEGTQVQRQQVPEELKRFFGPDAP
GQQQSSRPFEGLGSGVIIDAAKGYVLTNNHVINNADKISVQLNDGREVDAKLLGRDEQSDIALLQLSDVKNLTAIKMADS
DQLRVGDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALVNLNGELIGINTAILAPSGGN
VGIGFAIPSNMAQNLSQQLIEFGEVKRGLLGIKGSEMTADMAKAFNTDAQRGAFVSEVLPKSAAAKAGIKAGDILVSVDG
KPVSSFAELRAKVGTTAPGKTIKVGLLRDGKPLEVSVTLDNSEGASTNAETLSPALQGVSLSNGAIPSGDKGVKIDRVDK
GSVAAQIGLQKDDVIIGVNRQRVENITTLRKVLEAKPPVMALNIVRGGETIYLLLR

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=319, Percent_Identity=36.9905956112853, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI4506141, Length=316, Percent_Identity=34.1772151898734, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI24308541, Length=307, Percent_Identity=30.2931596091205, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI7019477, Length=343, Percent_Identity=30.6122448979592, Blast_Score=122, Evalue=7e-28,
Organism=Escherichia coli, GI1789629, Length=457, Percent_Identity=71.7724288840263, Blast_Score=640, Evalue=0.0,
Organism=Escherichia coli, GI1786356, Length=455, Percent_Identity=59.3406593406593, Blast_Score=524, Evalue=1e-150,
Organism=Escherichia coli, GI1789630, Length=280, Percent_Identity=47.1428571428571, Blast_Score=221, Evalue=9e-59,
Organism=Drosophila melanogaster, GI24646839, Length=289, Percent_Identity=33.2179930795848, Blast_Score=130, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 47357; Mature: 47357

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKSLILSALAMSIGITLTSVPAANAAMPVAVQGQQLPSLAPMLEKVLPAVVSVHVEGT
CCCHHHHHHHHHHHHCEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHEEEECCC
QVQRQQVPEELKRFFGPDAPGQQQSSRPFEGLGSGVIIDAAKGYVLTNNHVINNADKISV
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCEEEECCCCEEEECCEEECCCEEEEE
QLNDGREVDAKLLGRDEQSDIALLQLSDVKNLTAIKMADSDQLRVGDFAVAVGNPFGLGQ
EECCCCCCCHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCEEECEEEEEECCCCCCCH
TATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALVNLNGELIGINTAILAPSGGN
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEEEEECCCCC
VGIGFAIPSNMAQNLSQQLIEFGEVKRGLLGIKGSEMTADMAKAFNTDAQRGAFVSEVLP
EEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHCCHHHHHHHC
KSAAAKAGIKAGDILVSVDGKPVSSFAELRAKVGTTAPGKTIKVGLLRDGKPLEVSVTLD
CHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEEEE
NSEGASTNAETLSPALQGVSLSNGAIPSGDKGVKIDRVDKGSVAAQIGLQKDDVIIGVNR
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCEEEECCH
QRVENITTLRKVLEAKPPVMALNIVRGGETIYLLLR
HHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEEC
>Mature Secondary Structure
MNKKSLILSALAMSIGITLTSVPAANAAMPVAVQGQQLPSLAPMLEKVLPAVVSVHVEGT
CCCHHHHHHHHHHHHCEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHEEEECCC
QVQRQQVPEELKRFFGPDAPGQQQSSRPFEGLGSGVIIDAAKGYVLTNNHVINNADKISV
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCEEEECCCCEEEECCEEECCCEEEEE
QLNDGREVDAKLLGRDEQSDIALLQLSDVKNLTAIKMADSDQLRVGDFAVAVGNPFGLGQ
EECCCCCCCHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCEEECEEEEEECCCCCCCH
TATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALVNLNGELIGINTAILAPSGGN
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEEEEECCCCC
VGIGFAIPSNMAQNLSQQLIEFGEVKRGLLGIKGSEMTADMAKAFNTDAQRGAFVSEVLP
EEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHCCHHHHHHHC
KSAAAKAGIKAGDILVSVDGKPVSSFAELRAKVGTTAPGKTIKVGLLRDGKPLEVSVTLD
CHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEEEE
NSEGASTNAETLSPALQGVSLSNGAIPSGDKGVKIDRVDKGSVAAQIGLQKDDVIIGVNR
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCEEEECCH
QRVENITTLRKVLEAKPPVMALNIVRGGETIYLLLR
HHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]