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The map label for this gene is torZ [C]

Identifier: 157372066

GI number: 157372066

Start: 4240534

End: 4242792

Strand: Reverse

Name: torZ [C]

Synonym: Spro_3831

Alternate gene names: 157372066

Gene position: 4242792-4240534 (Counterclockwise)

Preceding gene: 157372068

Following gene: 157372065

Centisome position: 77.87

GC content: 59.89

Gene sequence:

>2259_bases
ATGTCGATTAAACGTTACCCGCAACTCGCTCACTGGGGGGCGTATACCGCCGTGGTTGAAGACGGCAGGCTTATCCGCTG
TGAGCCGTTTGCAGGCGATCCGGATCCTTCCCCGATGCTCGACTCCATCGCGCCGATGGCCTATTCCGACAAACGGATCC
GTAAGCCGGCGGTGCGCCGCTCCTGGCTGCAAAAGCGTGAAGGCAGTGACCGCACGCTGCGTGGCCGTGAGGATTTTGTC
GAAGTGGACTGGGATCTGGCGCTCGATCTGGTGGCGGAAGAAAACCGCCGCGTGCGCGATCGCTATGGCCCCTCGGGCCT
GTTTACCGGCTCCTATGGTTGGTCATCCGCCGGGCGTTTGCATCATGCGCGTTCGCTGGTGCGGCGCTTTTATTTCGGCG
GTGGCGGCGGTGTTGATCAGTTAGGCAACTACAGTTGGGGCGCTGCGCAGTTTTTCCTGCCGTATGTGATTGGTACCTTC
ACCCCATTGACCGGGCGCGTCACCAGTTGGCCGAGCGTGGTTGAGCACTGTGAACTGTTTGTCGCTTTCGGTGGGTTGGC
ACTGAAAAATGCCCAGGTATCGTCCGGTGGCGCGGCGGAACACTCGCTCAAACCATGGTTGCAAAAACTGGTGCAGAAAG
GCACCCCGGTTATCAACATCAGCCCGATGCGTGATGACTGCCCGGCATTTGTGAATGCCGAATGGATCCCAATCCGCCCG
AATACCGATGTGGCGTTAATGCTGGCACTGGCGTATGAAATTCAGCGTCGGGGCGCGCAGGACGAAGCATTTCTCTATAG
CCACTGTGCCGGTTATGACCAACTGGCGAGTTATCTGCGCGGCACCGATGACGGCGTGGCGAAAACCCCAGAATGGGCCA
GTGCGATCACCGGTATCCCGGCGGCGCGCATTGGCTTGCTCGCACAGCAACTGATTGGCGTGCGAAGCTTTCTTACCTGC
TCCTATTCCGTTCAGCGCGCTCATCGTGGCGAACAGCCCTATTGGATGATGATTGCCCTGTCGGCGATGCTCGGCCAGGT
TGGGCTACCGGGCGGCGGCTTCTCGTTTGGCCACGGTTCAATGAACGGGGTTGGCAACCCGCGCGTGGATACGCCGGGGC
CAATGATGCCGGTGGGGCCTAACCCTTGTGGGTTGGCGATCCCGGTGGCACGCATTTGCGACATGTTGCTGCAACCGGGC
GAACCCTACCAGTTCCGTGGCGAGACGCTGCACTACCCGGATATCCATCTGGTGCACTGGGCCGGGGGTAACCCGTTCCA
TCATCACCAACAGTTAAACCGGCTGGTGGAAGGCTGGCAGAAGCCGGATACGGTGATTGTGCAGGATATCTGGTGGACCC
CGGCCGCCAAAATGGCAGATATCGTGCTGCCGGTAACCACCTCGCTGGAACGTAACGATATCGGCGGTTCATCGCGCGAT
CGCTACGTGTTGGCGATGCATCAGGCCATTGCGCCGCAGCATCAGGCGCGTAACGACTTTGATATTTTTGCCGATCTGGC
GGAGCGACTGGGTTACCGCGAACAATTCACCGAAAATCGCGATGAACGAGCCTGGATCGAATCTATCTATCAGCAGTGCG
GACAGGCGCAGGCCGGTACCGGTGTGGAATGGCCCGAGTTCGAGGATTTTTGGCGTAAAGGCTATGTCGAGCTGCCGGCA
CCGGCGAAAGAATTTGTGTTCTTTGACGACTTCCGCGCCGACCCACAGGCCAACCCGCTGCAAACTCCGAGCGGCAAGAT
TGAGTTGTTCAGCGAGAAAATTGCCGGCTACGGTTATGCTGATTTTGCACCGCATCCGCAGTGGCAGCCGCCGGTCGAAT
GGCTGGGGGCGCCACAGGCCAAAGAGTGGCCGCTGCACCTGATTTCCATCCAGCCGAGCGATCGTTTACACAGCCAGATG
GACCCGGCCCCCCTGGCGCAGGGCAATAAAACCGCCGGGCGCGAAACGCTGTATATGCACCCGCAGGATGCGATAAAACG
CGGTATTGTCGATGGCGTTGAGGTGTTGGTCAGCAATGCGCGCGGCAGTTGTCTGGCGGGCGTCGCTATTACCGACGGCG
TTACACCGGGCGTGGTGCTGATGGCCACCGGTGCCTGGTTTGATCCGGGCTTCGGCAGCCAGCGGCTGCAGGTGGAACAG
TCCGGCAATCCGAACGTATTAACGCTGGATATCGGCACCTCGCCGTTAACTCAGGGGCCGAACGCCATGAGCTGCCTGGT
CGAGGTGAGCGTTCGATAG

Upstream 100 bases:

>100_bases
GTGCTTAGACCTGCGCAGCTCAGTAATAGAGCCATTTGTGCTTTGGCGGCGCACGGCAGCTAATGTTACTTTTGTGTATC
CCATTTTGTTTGAGAACCGC

Downstream 100 bases:

>100_bases
GTAATATACCCTATGAATTTCAAGTTGCAGCTAGGCGACCAACTCGCTCATCCCCAGGCGCTTACTTGAGTAAGTAACTG
GGGTGAGCGAGTGCAGATAA

Product: molybdopterin oxidoreductase

Products: Biotin [C]

Alternate protein names: BDS reductase; BSO reductase [H]

Number of amino acids: Translated: 752; Mature: 751

Protein sequence:

>752_residues
MSIKRYPQLAHWGAYTAVVEDGRLIRCEPFAGDPDPSPMLDSIAPMAYSDKRIRKPAVRRSWLQKREGSDRTLRGREDFV
EVDWDLALDLVAEENRRVRDRYGPSGLFTGSYGWSSAGRLHHARSLVRRFYFGGGGGVDQLGNYSWGAAQFFLPYVIGTF
TPLTGRVTSWPSVVEHCELFVAFGGLALKNAQVSSGGAAEHSLKPWLQKLVQKGTPVINISPMRDDCPAFVNAEWIPIRP
NTDVALMLALAYEIQRRGAQDEAFLYSHCAGYDQLASYLRGTDDGVAKTPEWASAITGIPAARIGLLAQQLIGVRSFLTC
SYSVQRAHRGEQPYWMMIALSAMLGQVGLPGGGFSFGHGSMNGVGNPRVDTPGPMMPVGPNPCGLAIPVARICDMLLQPG
EPYQFRGETLHYPDIHLVHWAGGNPFHHHQQLNRLVEGWQKPDTVIVQDIWWTPAAKMADIVLPVTTSLERNDIGGSSRD
RYVLAMHQAIAPQHQARNDFDIFADLAERLGYREQFTENRDERAWIESIYQQCGQAQAGTGVEWPEFEDFWRKGYVELPA
PAKEFVFFDDFRADPQANPLQTPSGKIELFSEKIAGYGYADFAPHPQWQPPVEWLGAPQAKEWPLHLISIQPSDRLHSQM
DPAPLAQGNKTAGRETLYMHPQDAIKRGIVDGVEVLVSNARGSCLAGVAITDGVTPGVVLMATGAWFDPGFGSQRLQVEQ
SGNPNVLTLDIGTSPLTQGPNAMSCLVEVSVR

Sequences:

>Translated_752_residues
MSIKRYPQLAHWGAYTAVVEDGRLIRCEPFAGDPDPSPMLDSIAPMAYSDKRIRKPAVRRSWLQKREGSDRTLRGREDFV
EVDWDLALDLVAEENRRVRDRYGPSGLFTGSYGWSSAGRLHHARSLVRRFYFGGGGGVDQLGNYSWGAAQFFLPYVIGTF
TPLTGRVTSWPSVVEHCELFVAFGGLALKNAQVSSGGAAEHSLKPWLQKLVQKGTPVINISPMRDDCPAFVNAEWIPIRP
NTDVALMLALAYEIQRRGAQDEAFLYSHCAGYDQLASYLRGTDDGVAKTPEWASAITGIPAARIGLLAQQLIGVRSFLTC
SYSVQRAHRGEQPYWMMIALSAMLGQVGLPGGGFSFGHGSMNGVGNPRVDTPGPMMPVGPNPCGLAIPVARICDMLLQPG
EPYQFRGETLHYPDIHLVHWAGGNPFHHHQQLNRLVEGWQKPDTVIVQDIWWTPAAKMADIVLPVTTSLERNDIGGSSRD
RYVLAMHQAIAPQHQARNDFDIFADLAERLGYREQFTENRDERAWIESIYQQCGQAQAGTGVEWPEFEDFWRKGYVELPA
PAKEFVFFDDFRADPQANPLQTPSGKIELFSEKIAGYGYADFAPHPQWQPPVEWLGAPQAKEWPLHLISIQPSDRLHSQM
DPAPLAQGNKTAGRETLYMHPQDAIKRGIVDGVEVLVSNARGSCLAGVAITDGVTPGVVLMATGAWFDPGFGSQRLQVEQ
SGNPNVLTLDIGTSPLTQGPNAMSCLVEVSVR
>Mature_751_residues
SIKRYPQLAHWGAYTAVVEDGRLIRCEPFAGDPDPSPMLDSIAPMAYSDKRIRKPAVRRSWLQKREGSDRTLRGREDFVE
VDWDLALDLVAEENRRVRDRYGPSGLFTGSYGWSSAGRLHHARSLVRRFYFGGGGGVDQLGNYSWGAAQFFLPYVIGTFT
PLTGRVTSWPSVVEHCELFVAFGGLALKNAQVSSGGAAEHSLKPWLQKLVQKGTPVINISPMRDDCPAFVNAEWIPIRPN
TDVALMLALAYEIQRRGAQDEAFLYSHCAGYDQLASYLRGTDDGVAKTPEWASAITGIPAARIGLLAQQLIGVRSFLTCS
YSVQRAHRGEQPYWMMIALSAMLGQVGLPGGGFSFGHGSMNGVGNPRVDTPGPMMPVGPNPCGLAIPVARICDMLLQPGE
PYQFRGETLHYPDIHLVHWAGGNPFHHHQQLNRLVEGWQKPDTVIVQDIWWTPAAKMADIVLPVTTSLERNDIGGSSRDR
YVLAMHQAIAPQHQARNDFDIFADLAERLGYREQFTENRDERAWIESIYQQCGQAQAGTGVEWPEFEDFWRKGYVELPAP
AKEFVFFDDFRADPQANPLQTPSGKIELFSEKIAGYGYADFAPHPQWQPPVEWLGAPQAKEWPLHLISIQPSDRLHSQMD
PAPLAQGNKTAGRETLYMHPQDAIKRGIVDGVEVLVSNARGSCLAGVAITDGVTPGVVLMATGAWFDPGFGSQRLQVEQS
GNPNVLTLDIGTSPLTQGPNAMSCLVEVSVR

Specific function: This enzyme may serve as a scavenger, allowing the cell to utilize biotin sulfoxide as a biotin source. It reduces a spontaneous oxidation product of biotin, D-biotin D-sulfoxide (BSO or BDS), back to biotin [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081994, Length=761, Percent_Identity=40.0788436268068, Blast_Score=545, Evalue=1e-156,
Organism=Escherichia coli, GI145693196, Length=760, Percent_Identity=40.2631578947368, Blast_Score=537, Evalue=1e-153,
Organism=Escherichia coli, GI1787231, Length=764, Percent_Identity=41.3612565445026, Blast_Score=528, Evalue=1e-151,
Organism=Escherichia coli, GI87081797, Length=735, Percent_Identity=31.156462585034, Blast_Score=290, Evalue=2e-79,
Organism=Escherichia coli, GI1787870, Length=736, Percent_Identity=28.125, Blast_Score=252, Evalue=5e-68,
Organism=Escherichia coli, GI171474008, Length=735, Percent_Identity=28.7074829931973, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI3868721, Length=771, Percent_Identity=20.4928664072633, Blast_Score=105, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.7.2.3 [C]

Molecular weight: Translated: 83013; Mature: 82882

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKRYPQLAHWGAYTAVVEDGRLIRCEPFAGDPDPSPMLDSIAPMAYSDKRIRKPAVRR
CCCCCCCCHHHCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHCCCCCCCHHHHCHHHHH
SWLQKREGSDRTLRGREDFVEVDWDLALDLVAEENRRVRDRYGPSGLFTGSYGWSSAGRL
HHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHCCHHHHHHCCCCCEEECCCCCCCCCHH
HHARSLVRRFYFGGGGGVDQLGNYSWGAAQFFLPYVIGTFTPLTGRVTSWPSVVEHCELF
HHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
VAFGGLALKNAQVSSGGAAEHSLKPWLQKLVQKGTPVINISPMRDDCPAFVNAEWIPIRP
HHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEECC
NTDVALMLALAYEIQRRGAQDEAFLYSHCAGYDQLASYLRGTDDGVAKTPEWASAITGIP
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHCCCC
AARIGLLAQQLIGVRSFLTCSYSVQRAHRGEQPYWMMIALSAMLGQVGLPGGGFSFGHGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCC
MNGVGNPRVDTPGPMMPVGPNPCGLAIPVARICDMLLQPGEPYQFRGETLHYPDIHLVHW
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEECCCEECCCCEEEEEE
AGGNPFHHHQQLNRLVEGWQKPDTVIVQDIWWTPAAKMADIVLPVTTSLERNDIGGSSRD
CCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHEEEECCCCCCCCCCCCCCCC
RYVLAMHQAIAPQHQARNDFDIFADLAERLGYREQFTENRDERAWIESIYQQCGQAQAGT
CEEEEEHHHHCCHHHCCCCHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCC
GVEWPEFEDFWRKGYVELPAPAKEFVFFDDFRADPQANPLQTPSGKIELFSEKIAGYGYA
CCCCCCHHHHHHCCCEECCCCHHHEEEEECCCCCCCCCCCCCCCCCEEEEHHHHCCCCCC
DFAPHPQWQPPVEWLGAPQAKEWPLHLISIQPSDRLHSQMDPAPLAQGNKTAGRETLYMH
CCCCCCCCCCCHHHCCCCCCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCEEEEC
PQDAIKRGIVDGVEVLVSNARGSCLAGVAITDGVTPGVVLMATGAWFDPGFGSQRLQVEQ
CHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCEEEEEC
SGNPNVLTLDIGTSPLTQGPNAMSCLVEVSVR
CCCCCEEEEECCCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure 
SIKRYPQLAHWGAYTAVVEDGRLIRCEPFAGDPDPSPMLDSIAPMAYSDKRIRKPAVRR
CCCCCCCHHHCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHCCCCCCCHHHHCHHHHH
SWLQKREGSDRTLRGREDFVEVDWDLALDLVAEENRRVRDRYGPSGLFTGSYGWSSAGRL
HHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHCCHHHHHHCCCCCEEECCCCCCCCCHH
HHARSLVRRFYFGGGGGVDQLGNYSWGAAQFFLPYVIGTFTPLTGRVTSWPSVVEHCELF
HHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
VAFGGLALKNAQVSSGGAAEHSLKPWLQKLVQKGTPVINISPMRDDCPAFVNAEWIPIRP
HHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEECC
NTDVALMLALAYEIQRRGAQDEAFLYSHCAGYDQLASYLRGTDDGVAKTPEWASAITGIP
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHCCCC
AARIGLLAQQLIGVRSFLTCSYSVQRAHRGEQPYWMMIALSAMLGQVGLPGGGFSFGHGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCC
MNGVGNPRVDTPGPMMPVGPNPCGLAIPVARICDMLLQPGEPYQFRGETLHYPDIHLVHW
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEECCCEECCCCEEEEEE
AGGNPFHHHQQLNRLVEGWQKPDTVIVQDIWWTPAAKMADIVLPVTTSLERNDIGGSSRD
CCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHEEEECCCCCCCCCCCCCCCC
RYVLAMHQAIAPQHQARNDFDIFADLAERLGYREQFTENRDERAWIESIYQQCGQAQAGT
CEEEEEHHHHCCHHHCCCCHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCC
GVEWPEFEDFWRKGYVELPAPAKEFVFFDDFRADPQANPLQTPSGKIELFSEKIAGYGYA
CCCCCCHHHHHHCCCEECCCCHHHEEEEECCCCCCCCCCCCCCCCCEEEEHHHHCCCCCC
DFAPHPQWQPPVEWLGAPQAKEWPLHLISIQPSDRLHSQMDPAPLAQGNKTAGRETLYMH
CCCCCCCCCCCHHHCCCCCCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCEEEEC
PQDAIKRGIVDGVEVLVSNARGSCLAGVAITDGVTPGVVLMATGAWFDPGFGSQRLQVEQ
CHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCEEEEEC
SGNPNVLTLDIGTSPLTQGPNAMSCLVEVSVR
CCCCCEEEEECCCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds) [C]

Specific reaction: Reduces A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds), Back To Biotin. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7733660 [H]