Click here to switch to the map view.

The map label for this gene is yiaV [H]

Identifier: 157371928

GI number: 157371928

Start: 4084620

End: 4085756

Strand: Reverse

Name: yiaV [H]

Synonym: Spro_3693

Alternate gene names: 157371928

Gene position: 4085756-4084620 (Counterclockwise)

Preceding gene: 157371929

Following gene: 157371924

Centisome position: 74.98

GC content: 55.15

Gene sequence:

>1137_bases
ATGGATCTCTTAATTATTCTCAGCTACGTTGCGCTGAGCTACGGCGTATTCAAACTGTTCCGTATTCCGGTCAATAAATG
GACGGTGCCGACGGCGGTGCTTGGCGGTATTTTCATTGTGGGTGCCTTAATCCTGGGCATGAATTACAACCATCCTTATA
CCTACCGGGCGCAGAAGATCGCGATATCCGTACCGATCGTCCCGCAGGTCTCGGGGATGATTGTTGAAGTCACCGATAAA
ACCAACGTGTTACTGCGCAAAGGGGAAGTTCTGTTTCGCCTTGATGATACCCGCTACCGCGCCCGACTCAACAAACTGCA
GGCGGAGCTTGCCGGTGCGCAGGCGGATGTACGTGGGCGCCAGGCGACATTGAATGAGTCTGCCGCTAATGTTCAGCGGG
TAAATGCCGAGTATGAACGGGCCCGCAAGGATTATCAGCGCTATGCCAAAGGCGCGACCATGGCGGTCAACCCTTTTTCT
GAGCAAGACATCAGCCATGCGCAGCAACAATACCAGGCGCAATCCGCCGCGCTGCAGGCCGCCAGGGCCCAGCATCAGCA
GGCGAAGGAACAGCTTTCGGGCCACTACAACGGTGAAGATGCCCATATCGCCAGCCTGAAATCACAAATTGCAGAGGCCA
CTTATAACCTGGAACAAACCACTATTCGCGCACCCAGCGACGGTTATGTTACCCAGGTACTGGCCAGACCGGGCACCACC
GCAGTGCGTTTGCCTTTCAAGCCGGTGATGATTTTTATTCCGCAGCAAAAACGGCAGGTGGTGGCGGTATTCCGGCAAAA
CTCGATCCTGCGTTTAACCGAGGGCGATAAAGCCGAGGTGGTATTTAACGGTTTGCCGGGCAAAATCTATGGTGGCTCGG
TGACGCGAGTGTTGCCGGTGGTACCGGACGGCAGCTACCAGGCCAGCGGGGCATTGCAGGGGTTAAATGTCGGCGCCCAA
CAGGAAGGGGTTTACGTGATGATTGATCTGGCCCCCAGCAGGGAACTCGACAAACTGCCCGATGGCGTGACGGCACAGAC
TGCGGTGTATACCGAGCACTTTGAGCATCTTTCCATTATGCGTAAAGTCCTGCTACGCATGACCAGCTGGATGCACTACC
TGTATTTGGATCACTAG

Upstream 100 bases:

>100_bases
GCTGCAGGCACGAATTAATCGGCTCGAAAGTGAATTGCAGCGTATGCAGACGCAGGTTGCCGCTCAAAGCTCGTCGTCCA
ATAAAGGTTAAGCAAACAGT

Downstream 100 bases:

>100_bases
TGGCGAGAGGTTTGTGCCGTTGATTCTAAAGCCCGTAATTTAGGTTACGGGTTTTAGAGGAACTTGGCCGAGGTTTGGTA
AATGGTACTTTACTCGTTAA

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MDLLIILSYVALSYGVFKLFRIPVNKWTVPTAVLGGIFIVGALILGMNYNHPYTYRAQKIAISVPIVPQVSGMIVEVTDK
TNVLLRKGEVLFRLDDTRYRARLNKLQAELAGAQADVRGRQATLNESAANVQRVNAEYERARKDYQRYAKGATMAVNPFS
EQDISHAQQQYQAQSAALQAARAQHQQAKEQLSGHYNGEDAHIASLKSQIAEATYNLEQTTIRAPSDGYVTQVLARPGTT
AVRLPFKPVMIFIPQQKRQVVAVFRQNSILRLTEGDKAEVVFNGLPGKIYGGSVTRVLPVVPDGSYQASGALQGLNVGAQ
QEGVYVMIDLAPSRELDKLPDGVTAQTAVYTEHFEHLSIMRKVLLRMTSWMHYLYLDH

Sequences:

>Translated_378_residues
MDLLIILSYVALSYGVFKLFRIPVNKWTVPTAVLGGIFIVGALILGMNYNHPYTYRAQKIAISVPIVPQVSGMIVEVTDK
TNVLLRKGEVLFRLDDTRYRARLNKLQAELAGAQADVRGRQATLNESAANVQRVNAEYERARKDYQRYAKGATMAVNPFS
EQDISHAQQQYQAQSAALQAARAQHQQAKEQLSGHYNGEDAHIASLKSQIAEATYNLEQTTIRAPSDGYVTQVLARPGTT
AVRLPFKPVMIFIPQQKRQVVAVFRQNSILRLTEGDKAEVVFNGLPGKIYGGSVTRVLPVVPDGSYQASGALQGLNVGAQ
QEGVYVMIDLAPSRELDKLPDGVTAQTAVYTEHFEHLSIMRKVLLRMTSWMHYLYLDH
>Mature_378_residues
MDLLIILSYVALSYGVFKLFRIPVNKWTVPTAVLGGIFIVGALILGMNYNHPYTYRAQKIAISVPIVPQVSGMIVEVTDK
TNVLLRKGEVLFRLDDTRYRARLNKLQAELAGAQADVRGRQATLNESAANVQRVNAEYERARKDYQRYAKGATMAVNPFS
EQDISHAQQQYQAQSAALQAARAQHQQAKEQLSGHYNGEDAHIASLKSQIAEATYNLEQTTIRAPSDGYVTQVLARPGTT
AVRLPFKPVMIFIPQQKRQVVAVFRQNSILRLTEGDKAEVVFNGLPGKIYGGSVTRVLPVVPDGSYQASGALQGLNVGAQ
QEGVYVMIDLAPSRELDKLPDGVTAQTAVYTEHFEHLSIMRKVLLRMTSWMHYLYLDH

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790012, Length=378, Percent_Identity=59.7883597883598, Blast_Score=489, Evalue=1e-139,
Organism=Escherichia coli, GI1790024, Length=378, Percent_Identity=60.0529100529101, Blast_Score=488, Evalue=1e-139,
Organism=Escherichia coli, GI1790519, Length=293, Percent_Identity=28.3276450511945, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI87081951, Length=284, Percent_Identity=27.112676056338, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788711, Length=230, Percent_Identity=24.3478260869565, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1789637, Length=284, Percent_Identity=27.4647887323944, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42017; Mature: 42017

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLIILSYVALSYGVFKLFRIPVNKWTVPTAVLGGIFIVGALILGMNYNHPYTYRAQKI
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEE
AISVPIVPQVSGMIVEVTDKTNVLLRKGEVLFRLDDTRYRARLNKLQAELAGAQADVRGR
EEEECCCCCCCCEEEEEECCCCEEEECCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCC
QATLNESAANVQRVNAEYERARKDYQRYAKGATMAVNPFSEQDISHAQQQYQAQSAALQA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
ARAQHQQAKEQLSGHYNGEDAHIASLKSQIAEATYNLEQTTIRAPSDGYVTQVLARPGTT
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHEECCCCC
AVRLPFKPVMIFIPQQKRQVVAVFRQNSILRLTEGDKAEVVFNGLPGKIYGGSVTRVLPV
EEEECCCEEEEEECCCHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCEECCCEEEEEEE
VPDGSYQASGALQGLNVGAQQEGVYVMIDLAPSRELDKLPDGVTAQTAVYTEHFEHLSIM
CCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHCCCCCCHHHHHHHHHHHHHHHH
RKVLLRMTSWMHYLYLDH
HHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MDLLIILSYVALSYGVFKLFRIPVNKWTVPTAVLGGIFIVGALILGMNYNHPYTYRAQKI
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEE
AISVPIVPQVSGMIVEVTDKTNVLLRKGEVLFRLDDTRYRARLNKLQAELAGAQADVRGR
EEEECCCCCCCCEEEEEECCCCEEEECCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCC
QATLNESAANVQRVNAEYERARKDYQRYAKGATMAVNPFSEQDISHAQQQYQAQSAALQA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
ARAQHQQAKEQLSGHYNGEDAHIASLKSQIAEATYNLEQTTIRAPSDGYVTQVLARPGTT
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHEECCCCC
AVRLPFKPVMIFIPQQKRQVVAVFRQNSILRLTEGDKAEVVFNGLPGKIYGGSVTRVLPV
EEEECCCEEEEEECCCHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCEECCCEEEEEEE
VPDGSYQASGALQGLNVGAQQEGVYVMIDLAPSRELDKLPDGVTAQTAVYTEHFEHLSIM
CCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHCCCCCCHHHHHHHHHHHHHHHH
RKVLLRMTSWMHYLYLDH
HHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]