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The map label for this gene is ptrB [H]

Identifier: 157371704

GI number: 157371704

Start: 3837672

End: 3839807

Strand: Reverse

Name: ptrB [H]

Synonym: Spro_3467

Alternate gene names: 157371704

Gene position: 3839807-3837672 (Counterclockwise)

Preceding gene: 157371705

Following gene: 157371703

Centisome position: 70.47

GC content: 55.95

Gene sequence:

>2136_bases
ATGAAACAAACACTTCTGTCGGGCCGCCAGCGTTGGCGTGCGGCCACCTATGCCGTGATTTCATTGAGCTTATTGGGCCA
GGCCGCCTGGGCGCAGCCGTTGGCGCCCAGCGCCGAGATTATCCCGCACCCATTAACCGCCCAGGGGGAAACCCGGGTGG
ATGATTATTATTGGCTGCGTGACGACAGCCGGCAAAATAAAAAGGTGCTGAATTATCTGACGGCGGAAAACCGTTATACC
GAGCAGATGATGCAGCCGTATAAAAAACTGCGCGATAGGCTGTATCAGGAAATGCTGGGCCGCATCAGCCCGGAAGATCG
CTCGGTGCCCTACCAACTTAATGGGTATCGCTATCAGGAAAGCTATGCGGCAGGTAAAGACTTTGCCCTGTATCAACGTC
AGGCTCTGACTGCCGATGCGCCGTGGCAAACCTTGCTGGACGCCAATCAGCGTGCTGCAGGGCAGGATTATTACCGCTTG
GGTGGGATGGCGATCAGCCTGGATAACCAGCAGATGGCGATCGCTGAAGATCTGCAGGGGCGCAGGCAGTACCGGATTTC
GCTGCGTGAAATCGATAGCGGTAAATGGGCGCCGGAAGTGATTGAAAACACCTCCGGTGACATGGCGTGGGCCAATGACG
GCAAGACGCTATTTTATATTCGCAACCACCCGCAGACCCTGTTGCCATATCAGGTTTATCGCCATCAGTCCGGCACGCCG
GTTGCGGACGACAAACTTGTCTATCAGGAAAATGATGGCGGGTTCTATTTGAGCCTGGGTCGTTCTTCTTCGCGTGACTA
CGTCATTATTACCATCAGCGGCAATACCACTTCCGAGGCACGGCTGATTGACGCTAATCAGCCTCTGAGCACGCCGGTGT
TGTTTGCCGCGCGCAAGAACGGCCACGAGTATTATGTAGACCACTATCGCGGTGAGTTCTATCTGCGATCCAACCACCAA
AGCCCGCATTTTGGTCTGTATCACACCGCGGCAGTCGGCAAGCCATGGCAGGCGCTACTGGCACCACAGGAAAAGCGCGA
GGTGGAAGACTTCACGGTGTTCCGCGACTGGCTGGTAGTGAAGGAACGTGCTGATGGCCTGGTACAGCTACGGCAAATCA
GTTGGGACGGTAAAACCCAGCGCAGTATTCCGTTCGACGACGCCAGCTATATGGCCTGGCTGGGCTATAACCCGGAGCCG
GACAACCAGCAGCTGCGCTATGGCTATTCGGCGATGACAACCCCGACCCGCACATACCAATGGGATCTCAACAAAGGCGA
GCGCACCCTGCTGAAACAGCAGGAAGTGAAGGGAGTGGATCCCAGCCAGTACCACAGCGAGCGGGTGTGGATTAACGCGC
GTGACGGTGTGAAGGTGCCGGTCTCGCTGGTCTACAACAAAGCCATGTTCAAACCGGGGCACAGCCCGCTGCTGGTGTAC
GGTTATGGTGCCTATGGCATGAGTATGGATCCGGCCTTTAGCGCTAACCGCATTAGTTTGCTGGATCGCGGTTTCGTTTA
TGCGCTAATCCACGTGCGCGGTGGCGGTGAGCTGGGGCAGAACTGGTACCAACAGGGCAAGTTGACTCATAAGCCAAACA
CCTTCAGTGACTTTATCGACGCCACCCAGGCATTAATCCAACAGGGTTATGGTCAGCCGGGCCGTATTTACGCCATGGGG
GGCAGTGCCGGCGGCCTGCTGATGGGGGCAGTGATTAATCAGGCACCGCAGTTGTATAACGCGGTGGTGGCGCAGGTGCC
TTTTGTTGATGTGCTGACCACCATGCTGGACGACAGCATTCCGCTGACGGTCGGTGAATACGAAGAGTGGGGCAATCCGA
ATCAGCCGCAGGCCTATGCGTTGATGAAGTCCTATAGCCCGTATGACAACCTGGCTAAACAGGCCTATCCGAACCTGCTG
GTCACCAGCGGCCTGTATGACTCGCAGGTGCAATATTGGGAACCGGCCAAATGGGTAGCCAAACTGCGTCGTTTTAAACA
GGGTGATTCAGTGTTGCTGCTGGCGACCGATATGACGGCCGGCCACGGCGGAAAATCGGGCCGCCTGACGCGGCTGGAAA
ATAACGCGCTGGAATACAGTTTTATTATGGCGATGGATCAGAAAACACAGAAATAA

Upstream 100 bases:

>100_bases
GGCGGCGCTGGACGCCAGCCAATAATTTATTTCGTGAGCCGCGTTCTTTTGTTTACCCAAACAAAAGGGAGCTGCTGATG
CCAAACTATCGTGAGGGACC

Downstream 100 bases:

>100_bases
CCACTTTCACCGTCGGGTAATAAGCCCGGCGGTTTATTAAAACTATAAAAAATAAATTTACCGTCGATTCCGGCGGGCTT
TTTGCTGGGCATTGTCGGCC

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 711; Mature: 711

Protein sequence:

>711_residues
MKQTLLSGRQRWRAATYAVISLSLLGQAAWAQPLAPSAEIIPHPLTAQGETRVDDYYWLRDDSRQNKKVLNYLTAENRYT
EQMMQPYKKLRDRLYQEMLGRISPEDRSVPYQLNGYRYQESYAAGKDFALYQRQALTADAPWQTLLDANQRAAGQDYYRL
GGMAISLDNQQMAIAEDLQGRRQYRISLREIDSGKWAPEVIENTSGDMAWANDGKTLFYIRNHPQTLLPYQVYRHQSGTP
VADDKLVYQENDGGFYLSLGRSSSRDYVIITISGNTTSEARLIDANQPLSTPVLFAARKNGHEYYVDHYRGEFYLRSNHQ
SPHFGLYHTAAVGKPWQALLAPQEKREVEDFTVFRDWLVVKERADGLVQLRQISWDGKTQRSIPFDDASYMAWLGYNPEP
DNQQLRYGYSAMTTPTRTYQWDLNKGERTLLKQQEVKGVDPSQYHSERVWINARDGVKVPVSLVYNKAMFKPGHSPLLVY
GYGAYGMSMDPAFSANRISLLDRGFVYALIHVRGGGELGQNWYQQGKLTHKPNTFSDFIDATQALIQQGYGQPGRIYAMG
GSAGGLLMGAVINQAPQLYNAVVAQVPFVDVLTTMLDDSIPLTVGEYEEWGNPNQPQAYALMKSYSPYDNLAKQAYPNLL
VTSGLYDSQVQYWEPAKWVAKLRRFKQGDSVLLLATDMTAGHGGKSGRLTRLENNALEYSFIMAMDQKTQK

Sequences:

>Translated_711_residues
MKQTLLSGRQRWRAATYAVISLSLLGQAAWAQPLAPSAEIIPHPLTAQGETRVDDYYWLRDDSRQNKKVLNYLTAENRYT
EQMMQPYKKLRDRLYQEMLGRISPEDRSVPYQLNGYRYQESYAAGKDFALYQRQALTADAPWQTLLDANQRAAGQDYYRL
GGMAISLDNQQMAIAEDLQGRRQYRISLREIDSGKWAPEVIENTSGDMAWANDGKTLFYIRNHPQTLLPYQVYRHQSGTP
VADDKLVYQENDGGFYLSLGRSSSRDYVIITISGNTTSEARLIDANQPLSTPVLFAARKNGHEYYVDHYRGEFYLRSNHQ
SPHFGLYHTAAVGKPWQALLAPQEKREVEDFTVFRDWLVVKERADGLVQLRQISWDGKTQRSIPFDDASYMAWLGYNPEP
DNQQLRYGYSAMTTPTRTYQWDLNKGERTLLKQQEVKGVDPSQYHSERVWINARDGVKVPVSLVYNKAMFKPGHSPLLVY
GYGAYGMSMDPAFSANRISLLDRGFVYALIHVRGGGELGQNWYQQGKLTHKPNTFSDFIDATQALIQQGYGQPGRIYAMG
GSAGGLLMGAVINQAPQLYNAVVAQVPFVDVLTTMLDDSIPLTVGEYEEWGNPNQPQAYALMKSYSPYDNLAKQAYPNLL
VTSGLYDSQVQYWEPAKWVAKLRRFKQGDSVLLLATDMTAGHGGKSGRLTRLENNALEYSFIMAMDQKTQK
>Mature_711_residues
MKQTLLSGRQRWRAATYAVISLSLLGQAAWAQPLAPSAEIIPHPLTAQGETRVDDYYWLRDDSRQNKKVLNYLTAENRYT
EQMMQPYKKLRDRLYQEMLGRISPEDRSVPYQLNGYRYQESYAAGKDFALYQRQALTADAPWQTLLDANQRAAGQDYYRL
GGMAISLDNQQMAIAEDLQGRRQYRISLREIDSGKWAPEVIENTSGDMAWANDGKTLFYIRNHPQTLLPYQVYRHQSGTP
VADDKLVYQENDGGFYLSLGRSSSRDYVIITISGNTTSEARLIDANQPLSTPVLFAARKNGHEYYVDHYRGEFYLRSNHQ
SPHFGLYHTAAVGKPWQALLAPQEKREVEDFTVFRDWLVVKERADGLVQLRQISWDGKTQRSIPFDDASYMAWLGYNPEP
DNQQLRYGYSAMTTPTRTYQWDLNKGERTLLKQQEVKGVDPSQYHSERVWINARDGVKVPVSLVYNKAMFKPGHSPLLVY
GYGAYGMSMDPAFSANRISLLDRGFVYALIHVRGGGELGQNWYQQGKLTHKPNTFSDFIDATQALIQQGYGQPGRIYAMG
GSAGGLLMGAVINQAPQLYNAVVAQVPFVDVLTTMLDDSIPLTVGEYEEWGNPNQPQAYALMKSYSPYDNLAKQAYPNLL
VTSGLYDSQVQYWEPAKWVAKLRRFKQGDSVLLLATDMTAGHGGKSGRLTRLENNALEYSFIMAMDQKTQK

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=702, Percent_Identity=27.7777777777778, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI284172420, Length=543, Percent_Identity=28.9134438305709, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI284172413, Length=543, Percent_Identity=28.9134438305709, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI70778815, Length=543, Percent_Identity=28.9134438305709, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI284172438, Length=543, Percent_Identity=28.9134438305709, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI284172431, Length=543, Percent_Identity=28.9134438305709, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI108860686, Length=539, Percent_Identity=27.6437847866419, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI108860692, Length=232, Percent_Identity=37.5, Blast_Score=148, Evalue=1e-35,
Organism=Escherichia coli, GI1788150, Length=679, Percent_Identity=54.9337260677467, Blast_Score=798, Evalue=0.0,
Organism=Drosophila melanogaster, GI24583414, Length=721, Percent_Identity=26.0748959778086, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI221510989, Length=701, Percent_Identity=25.1069900142653, Blast_Score=159, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 80779; Mature: 80779

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS00708 PRO_ENDOPEP_SER ; PS00501 SPASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQTLLSGRQRWRAATYAVISLSLLGQAAWAQPLAPSAEIIPHPLTAQGETRVDDYYWLR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEC
DDSRQNKKVLNYLTAENRYTEQMMQPYKKLRDRLYQEMLGRISPEDRSVPYQLNGYRYQE
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCEEEEH
SYAAGKDFALYQRQALTADAPWQTLLDANQRAAGQDYYRLGGMAISLDNQQMAIAEDLQG
HHCCCCCHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCEECCCEEEEECCCCHHHHHHHCC
RRQYRISLREIDSGKWAPEVIENTSGDMAWANDGKTLFYIRNHPQTLLPYQVYRHQSGTP
CCEEEEEEEECCCCCCCHHHHHCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHCCCCCC
VADDKLVYQENDGGFYLSLGRSSSRDYVIITISGNTTSEARLIDANQPLSTPVLFAARKN
CCCCEEEEEECCCCEEEEECCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCEEEEEECC
GHEYYVDHYRGEFYLRSNHQSPHFGLYHTAAVGKPWQALLAPQEKREVEDFTVFRDWLVV
CCEEEEEEECCEEEEECCCCCCCCCEEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHHH
KERADGLVQLRQISWDGKTQRSIPFDDASYMAWLGYNPEPDNQQLRYGYSAMTTPTRTYQ
HHHCCCEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCEECCCCEEEE
WDLNKGERTLLKQQEVKGVDPSQYHSERVWINARDGVKVPVSLVYNKAMFKPGHSPLLVY
EECCCCHHHHHHHHHHCCCCCHHHCCCEEEEECCCCCCCCHHHEEHHHHCCCCCCCEEEE
GYGAYGMSMDPAFSANRISLLDRGFVYALIHVRGGGELGQNWYQQGKLTHKPNTFSDFID
EECCCCCCCCCCCCCCCHHHHHCCEEEEEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHH
ATQALIQQGYGQPGRIYAMGGSAGGLLMGAVINQAPQLYNAVVAQVPFVDVLTTMLDDSI
HHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHCCCC
PLTVGEYEEWGNPNQPQAYALMKSYSPYDNLAKQAYPNLLVTSGLYDSQVQYWEPAKWVA
CEEECCHHHCCCCCCCHHHHHHHCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHH
KLRRFKQGDSVLLLATDMTAGHGGKSGRLTRLENNALEYSFIMAMDQKTQK
HHHHHCCCCCEEEEEECCCCCCCCCCCCEEEECCCCEEEEEEEEECCCCCC
>Mature Secondary Structure
MKQTLLSGRQRWRAATYAVISLSLLGQAAWAQPLAPSAEIIPHPLTAQGETRVDDYYWLR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEC
DDSRQNKKVLNYLTAENRYTEQMMQPYKKLRDRLYQEMLGRISPEDRSVPYQLNGYRYQE
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCEEEEH
SYAAGKDFALYQRQALTADAPWQTLLDANQRAAGQDYYRLGGMAISLDNQQMAIAEDLQG
HHCCCCCHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCEECCCEEEEECCCCHHHHHHHCC
RRQYRISLREIDSGKWAPEVIENTSGDMAWANDGKTLFYIRNHPQTLLPYQVYRHQSGTP
CCEEEEEEEECCCCCCCHHHHHCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHCCCCCC
VADDKLVYQENDGGFYLSLGRSSSRDYVIITISGNTTSEARLIDANQPLSTPVLFAARKN
CCCCEEEEEECCCCEEEEECCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCEEEEEECC
GHEYYVDHYRGEFYLRSNHQSPHFGLYHTAAVGKPWQALLAPQEKREVEDFTVFRDWLVV
CCEEEEEEECCEEEEECCCCCCCCCEEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHHH
KERADGLVQLRQISWDGKTQRSIPFDDASYMAWLGYNPEPDNQQLRYGYSAMTTPTRTYQ
HHHCCCEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCEECCCCEEEE
WDLNKGERTLLKQQEVKGVDPSQYHSERVWINARDGVKVPVSLVYNKAMFKPGHSPLLVY
EECCCCHHHHHHHHHHCCCCCHHHCCCEEEEECCCCCCCCHHHEEHHHHCCCCCCCEEEE
GYGAYGMSMDPAFSANRISLLDRGFVYALIHVRGGGELGQNWYQQGKLTHKPNTFSDFID
EECCCCCCCCCCCCCCCHHHHHCCEEEEEEEEECCCHHHHHHHHCCCCCCCCCHHHHHHH
ATQALIQQGYGQPGRIYAMGGSAGGLLMGAVINQAPQLYNAVVAQVPFVDVLTTMLDDSI
HHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHCCCC
PLTVGEYEEWGNPNQPQAYALMKSYSPYDNLAKQAYPNLLVTSGLYDSQVQYWEPAKWVA
CEEECCHHHCCCCCCCHHHHHHHCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHH
KLRRFKQGDSVLLLATDMTAGHGGKSGRLTRLENNALEYSFIMAMDQKTQK
HHHHHCCCCCEEEEEECCCCCCCCCCCCEEEECCCCEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]