BacMap

Definition	Serratia proteamaculans 568 chromosome, complete genome.
Accession	NC_009832
Length	5,448,853

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The map label for this gene is kduD [C]

Identifier: 157371303

GI number: 157371303

Start: 3373285

End: 3374058

Strand: Reverse

Name: kduD [C]

Synonym: Spro_3063

Alternate gene names: 157371303

Gene position: 3374058-3373285 (Counterclockwise)

Preceding gene: 157371305

Following gene: 157371302

Centisome position: 61.92

GC content: 57.88

Gene sequence:

>774_bases
ATGAGCAAACAATCTTTAAATGGAAAAGTGGTGTTGATCGCTGGCGGTGCGAAGAACCTGGGTGGCCTGGTGGCGCGCGA
TCTGGCGGCCGGCGGTGCAGCAGCGATAGTCGTGCATTACAACAGCGATGCGACCCGGGCGGCAGCGGAGGAAACGCTGA
AGGCGGTTAAAGCGGCGGGCGCACAGGCGATAACGGTGCAGGGCGATCTGACTAAACCGGCTAACGTGGCGCAGCTGTTT
GAGCAGGCTATCAAGGCATTCGGCAAAGTGGATATTGCCGTTAATACCGCCGGTTTGGTAATCAAAAAACCGATTGCCGA
GGTGACCGAAGCGGACTACGACAGCAGTTTTGACATCAATTCCAAGGCGGCTTTCTTCTTTATCCAGCAGGCGGGCAAGC
ATTTGGCCGACAACGGTCGCATTGTGTCCATCGTCAGCTCACTGCTGGCGGCTTATACGCCGTTTTATGCCGTCTATCCG
GGCAGCAAGGCACCGGTGGAGCACTTTACCCGTGCCGCGTCCAAAGAGTTTGGCGAGCGGGGCATCAGCGTGAACGCCAT
CGGCCCCGGCCCAATGGATACGCCGTTCTTCTACGGGCAGGAAAGCAAAGAGGCGGTGGAATATCACAGCAGCGCCGCGG
CGCTGAGCAAGTTCTCGAAAACCGGCCTGACCGACATTGAGGACATCGCGCCGATCGTCAAATTTCTGGTCACCGACGGC
TGGTGGATCACCGGGCAGACGCTGTTTGCCAACGGTGGCTATACTACCCGTTAA

Upstream 100 bases:

>100_bases
TTGACCGAAAAACCGGGATGGTTCATCCCGGTTTAGACAGATTATCTGAGCGGTCACAGTTCCTATACTCGTTACAACCT
TCACTAACGGAGTCACTGTA

Downstream 100 bases:

>100_bases
TATCAATTTTGCTGCGGCCGATGCCGCAGCCTGTTTAACAGGATGCACTGCCGGTGGATAAAATAGGGAGATTGCGGGTC
TTTATCCAGGTGGCCGAAGT

Product: short-chain dehydrogenase/reductase SDR

Products: @DEHY06.txt*3-Dehydro-2- Deoxy-D-Gluconate!; NADH. [C]

Alternate protein names: ORFC [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MSKQSLNGKVVLIAGGAKNLGGLVARDLAAGGAAAIVVHYNSDATRAAAEETLKAVKAAGAQAITVQGDLTKPANVAQLF
EQAIKAFGKVDIAVNTAGLVIKKPIAEVTEADYDSSFDINSKAAFFFIQQAGKHLADNGRIVSIVSSLLAAYTPFYAVYP
GSKAPVEHFTRAASKEFGERGISVNAIGPGPMDTPFFYGQESKEAVEYHSSAAALSKFSKTGLTDIEDIAPIVKFLVTDG
WWITGQTLFANGGYTTR

Sequences:

>Translated_257_residues
MSKQSLNGKVVLIAGGAKNLGGLVARDLAAGGAAAIVVHYNSDATRAAAEETLKAVKAAGAQAITVQGDLTKPANVAQLF
EQAIKAFGKVDIAVNTAGLVIKKPIAEVTEADYDSSFDINSKAAFFFIQQAGKHLADNGRIVSIVSSLLAAYTPFYAVYP
GSKAPVEHFTRAASKEFGERGISVNAIGPGPMDTPFFYGQESKEAVEYHSSAAALSKFSKTGLTDIEDIAPIVKFLVTDG
WWITGQTLFANGGYTTR
>Mature_256_residues
SKQSLNGKVVLIAGGAKNLGGLVARDLAAGGAAAIVVHYNSDATRAAAEETLKAVKAAGAQAITVQGDLTKPANVAQLFE
QAIKAFGKVDIAVNTAGLVIKKPIAEVTEADYDSSFDINSKAAFFFIQQAGKHLADNGRIVSIVSSLLAAYTPFYAVYPG
SKAPVEHFTRAASKEFGERGISVNAIGPGPMDTPFFYGQESKEAVEYHSSAAALSKFSKTGLTDIEDIAPIVKFLVTDGW
WITGQTLFANGGYTTR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=266, Percent_Identity=26.3157894736842, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI15277342, Length=264, Percent_Identity=26.8939393939394, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI7705925, Length=254, Percent_Identity=26.3779527559055, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI40254992, Length=254, Percent_Identity=28.740157480315, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=23.4615384615385, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI10190704, Length=258, Percent_Identity=25.1937984496124, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI31542939, Length=228, Percent_Identity=26.7543859649123, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI66933014, Length=259, Percent_Identity=27.7992277992278, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1789208, Length=263, Percent_Identity=30.0380228136882, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=27.6679841897233, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=26.3779527559055, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082160, Length=256, Percent_Identity=26.5625, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788459, Length=223, Percent_Identity=27.8026905829596, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=28.2868525896414, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=27.6923076923077, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367365, Length=193, Percent_Identity=30.0518134715026, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789378, Length=190, Percent_Identity=28.4210526315789, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=30.188679245283, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=264, Percent_Identity=28.030303030303, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=28.740157480315, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=28.4090909090909, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=29.2134831460674, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=28.735632183908, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=149, Percent_Identity=34.8993288590604, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=28.0442804428044, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=27.6119402985075, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=28.030303030303, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=275, Percent_Identity=28, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=29.5019157088123, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=29.1187739463602, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=27.9693486590038, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=259, Percent_Identity=26.2548262548263, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=27.3764258555133, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=29.1666666666667, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=27.6515151515151, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=25.5905511811024, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=26.1363636363636, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=266, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=255, Percent_Identity=27.4509803921569, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=241, Percent_Identity=27.3858921161826, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=240, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=210, Percent_Identity=27.1428571428571, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=26.2357414448669, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=26.4150943396226, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561272, Length=255, Percent_Identity=28.6274509803922, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=262, Percent_Identity=24.8091603053435, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71982365, Length=193, Percent_Identity=27.4611398963731, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322226, Length=195, Percent_Identity=29.2307692307692, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21355319, Length=264, Percent_Identity=29.5454545454545, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24639444, Length=260, Percent_Identity=31.9230769230769, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=26.0869565217391, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=27.2727272727273, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=28.0155642023346, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=25.296442687747, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24644337, Length=255, Percent_Identity=25.8823529411765, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI18859837, Length=270, Percent_Identity=25.1851851851852, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.125 [C]

Molecular weight: Translated: 26966; Mature: 26835

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQSLNGKVVLIAGGAKNLGGLVARDLAAGGAAAIVVHYNSDATRAAAEETLKAVKAAG
CCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCC
AQAITVQGDLTKPANVAQLFEQAIKAFGKVDIAVNTAGLVIKKPIAEVTEADYDSSFDIN
CEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEECCCEEEECCHHHHHHCCCCCCCCCC
SKAAFFFIQQAGKHLADNGRIVSIVSSLLAAYTPFYAVYPGSKAPVEHFTRAASKEFGER
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHC
GISVNAIGPGPMDTPFFYGQESKEAVEYHSSAAALSKFSKTGLTDIEDIAPIVKFLVTDG
CCEEEECCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
WWITGQTLFANGGYTTR
EEEECEEEEECCCCCCC
>Mature Secondary Structure 
SKQSLNGKVVLIAGGAKNLGGLVARDLAAGGAAAIVVHYNSDATRAAAEETLKAVKAAG
CCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCC
AQAITVQGDLTKPANVAQLFEQAIKAFGKVDIAVNTAGLVIKKPIAEVTEADYDSSFDIN
CEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEECCCEEEECCHHHHHHCCCCCCCCCC
SKAAFFFIQQAGKHLADNGRIVSIVSSLLAAYTPFYAVYPGSKAPVEHFTRAASKEFGER
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHC
GISVNAIGPGPMDTPFFYGQESKEAVEYHSSAAALSKFSKTGLTDIEDIAPIVKFLVTDG
CCEEEECCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
WWITGQTLFANGGYTTR
EEEECEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 15.4 {2-deoxygluconate}} [C]

Substrates: @DEOX03.txt*2-Deoxy-D-Gluconate!; NAD(+) [C]

Specific reaction: @DEOX03.txt*2-Deoxy-D-Gluconate! + NAD(+) = @DEHY06.txt*3-Dehydro-2- Deoxy-D-Gluconate! + NADH. [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8868443 [H]