Click here to switch to the map view.

The map label for this gene is mgtC [H]

Identifier: 157371285

GI number: 157371285

Start: 3354598

End: 3355296

Strand: Reverse

Name: mgtC [H]

Synonym: Spro_3045

Alternate gene names: 157371285

Gene position: 3355296-3354598 (Counterclockwise)

Preceding gene: 157371288

Following gene: 157371284

Centisome position: 61.58

GC content: 55.65

Gene sequence:

>699_bases
ATGGCTATGACTCCTTTTGTTTTAAATTTATTACTGGCGATGAGCCTGGGCGCGGTTATTGGCGCTGAGCGGCAGTGGCG
CCAACGTATGGCCGGTCTGCGCACCAATGCATTGGTGGCAACCGGAGCTGCGGTCTTTATCCTCAGTTCCATGTCTACCG
ATCCTTCCAGCGCCGGACGAGTTGCCGCGCAAATTGTCTCCGGTATCGGCTTTTTGGGTGCCGGGGTGATCATGCGTGAA
GGGTTGAATATCCGCGGGCTGAATACCGCCGCCACGCTATGGTGTTCTGCGGCGATCGGCGTGCTGTGCGGCCTTGGGCA
GTATTGGAACGCGGTACTGGCGACGTTGGTGATCCTGTGTGCGAATATCCTGCTGCGTGAAGCGGCGCAGCGCATCAACC
TGCAACCCCAGCAGCAGGCGACCGATCTGGAAGTGTGCTACCGCATTCAGGTCACCTGCGGTGAGCAGGATGAAATACTG
GTGCGTACCCTGATATTGCAGGCGCTAAATGGTGTGGCATTAAAATTACAATCGCTGCGCAGTGCGGATATTTCCATTCC
CGGTCAGTTGGAAGTTTGCGCGGAAATAACCGCAAATCCCTCGGTGCAAAAAGAAATTGAGGGCATAGTCTGTCGTGTCA
GCCTGGAAAAAAGCGTGAGTGCCGTGCGCTGGCGCATTGCTTCCGAATTGCCTGTTTGA

Upstream 100 bases:

>100_bases
AGGCATTCACACGCCCAACCGCTGATTTATTATCGGCGAGATTTCGCGTGTGCTAAAAAGCACATGATTTTATCTCCTGC
AGTTATTTAAGGGGAAAGTC

Downstream 100 bases:

>100_bases
TTATTGATAAATATTCACTTTATTAAGTGATAAGGAGGCGTCATGGACGGTGACCCCGAAAGTTTGATTATTAAGCGTTT
CTGGCGTGGAAATAAACCGC

Product: MgtC/SapB transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MAMTPFVLNLLLAMSLGAVIGAERQWRQRMAGLRTNALVATGAAVFILSSMSTDPSSAGRVAAQIVSGIGFLGAGVIMRE
GLNIRGLNTAATLWCSAAIGVLCGLGQYWNAVLATLVILCANILLREAAQRINLQPQQQATDLEVCYRIQVTCGEQDEIL
VRTLILQALNGVALKLQSLRSADISIPGQLEVCAEITANPSVQKEIEGIVCRVSLEKSVSAVRWRIASELPV

Sequences:

>Translated_232_residues
MAMTPFVLNLLLAMSLGAVIGAERQWRQRMAGLRTNALVATGAAVFILSSMSTDPSSAGRVAAQIVSGIGFLGAGVIMRE
GLNIRGLNTAATLWCSAAIGVLCGLGQYWNAVLATLVILCANILLREAAQRINLQPQQQATDLEVCYRIQVTCGEQDEIL
VRTLILQALNGVALKLQSLRSADISIPGQLEVCAEITANPSVQKEIEGIVCRVSLEKSVSAVRWRIASELPV
>Mature_231_residues
AMTPFVLNLLLAMSLGAVIGAERQWRQRMAGLRTNALVATGAAVFILSSMSTDPSSAGRVAAQIVSGIGFLGAGVIMREG
LNIRGLNTAATLWCSAAIGVLCGLGQYWNAVLATLVILCANILLREAAQRINLQPQQQATDLEVCYRIQVTCGEQDEILV
RTLILQALNGVALKLQSLRSADISIPGQLEVCAEITANPSVQKEIEGIVCRVSLEKSVSAVRWRIASELPV

Specific function: Virulence factor required for growth in low Mg(2+) medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na(+)/K(+)-ATPase [H]

COG id: COG1285

COG function: function code S; Uncharacterized membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MgtC/SapB family [H]

Homologues:

Organism=Escherichia coli, GI1789924, Length=148, Percent_Identity=37.8378378378378, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003416 [H]

Pfam domain/function: PF02308 MgtC [H]

EC number: NA

Molecular weight: Translated: 24713; Mature: 24582

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMTPFVLNLLLAMSLGAVIGAERQWRQRMAGLRTNALVATGAAVFILSSMSTDPSSAGR
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHH
VAAQIVSGIGFLGAGVIMREGLNIRGLNTAATLWCSAAIGVLCGLGQYWNAVLATLVILC
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ANILLREAAQRINLQPQQQATDLEVCYRIQVTCGEQDEILVRTLILQALNGVALKLQSLR
HHHHHHHHHHHCCCCCHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
SADISIPGQLEVCAEITANPSVQKEIEGIVCRVSLEKSVSAVRWRIASELPV
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHEEEEEHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AMTPFVLNLLLAMSLGAVIGAERQWRQRMAGLRTNALVATGAAVFILSSMSTDPSSAGR
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHH
VAAQIVSGIGFLGAGVIMREGLNIRGLNTAATLWCSAAIGVLCGLGQYWNAVLATLVILC
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ANILLREAAQRINLQPQQQATDLEVCYRIQVTCGEQDEILVRTLILQALNGVALKLQSLR
HHHHHHHHHHHCCCCCHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
SADISIPGQLEVCAEITANPSVQKEIEGIVCRVSLEKSVSAVRWRIASELPV
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHEEEEEHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA