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The map label for this gene is pcp2 [H]

Identifier: 157371233

GI number: 157371233

Start: 3291233

End: 3291880

Strand: Reverse

Name: pcp2 [H]

Synonym: Spro_2993

Alternate gene names: 157371233

Gene position: 3291880-3291233 (Counterclockwise)

Preceding gene: 157371261

Following gene: 157371229

Centisome position: 60.41

GC content: 56.94

Gene sequence:

>648_bases
ATGGACAGGGTATTAGTGACGGGTATAGAGCCGTTTGACGGCGACGCGATTAATCCTTCATGGCAGGTCGCGCAAGCTCT
GGCCGGGGAACAGGTGGCGGGTGCGGAGGTGGTGGTACGTCAATTGGCTTGCGTGCTGGGTTTGTCCAACCAGCAGCTCA
TTGCCGCGATTGAAGAGTTGCGCCCAAAGGTGGTTATCTGCCTGGGACTGGCGGGGGGGCGCGGCGAAATCTCGATTGAG
CGGGTGGCCATCAACCTGATCGATGCCCGTATTCCTGATAATGCCGGTAAACAACCGATAGATATCCCGGTGGTGGAGGG
CGGCCCGGTGGGCTATTTTTCCACGTTGCCGGTGAAGGCGATTGTGCATCATCTGCGTCAGTCAGGCATTCCGGCTGTGG
TTTCACATACGGCGGGGACCTACAATTGCAACCAGCTTTTTTATGGCCTGAGTCACCATATCGCCAGCCATAATCTGGCG
ATCAAGGGCGGTTTTATCCACATTCCTTACAGCCATGAGCTGGCGGTCAATCATCCGGGAAAACCAAGTATGGCGTTAGC
GACGATGGTCGCGGCGGTGCGCAGTATTGTGCATACCGCGCTGACGGTGGGGGAAGATTTAACCATCACCGGGGGAGCGC
TGCATTGA

Upstream 100 bases:

>100_bases
CATATTATGAATACTCTATATACAGATAATCCATTTCCAGAATCATACCGCGTTGTTTAGGCTGAGAGCACGCTGATTCA
ATAACAACATAGGTGTGGCG

Downstream 100 bases:

>100_bases
GGTGCCGGTAAAGTGTTCAGTGTTTCATGGTAGGAGTGCCGCATGTTGCGCCCGCCGGCATCATCAATGGGTTAAATCGG
GTCGAACTCATTTTCGACCC

Product: pyrrolidone-carboxylate peptidase

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase 2; Pyroglutamyl-peptidase I 2; PGP-I 2; Pyrase 2 [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MDRVLVTGIEPFDGDAINPSWQVAQALAGEQVAGAEVVVRQLACVLGLSNQQLIAAIEELRPKVVICLGLAGGRGEISIE
RVAINLIDARIPDNAGKQPIDIPVVEGGPVGYFSTLPVKAIVHHLRQSGIPAVVSHTAGTYNCNQLFYGLSHHIASHNLA
IKGGFIHIPYSHELAVNHPGKPSMALATMVAAVRSIVHTALTVGEDLTITGGALH

Sequences:

>Translated_215_residues
MDRVLVTGIEPFDGDAINPSWQVAQALAGEQVAGAEVVVRQLACVLGLSNQQLIAAIEELRPKVVICLGLAGGRGEISIE
RVAINLIDARIPDNAGKQPIDIPVVEGGPVGYFSTLPVKAIVHHLRQSGIPAVVSHTAGTYNCNQLFYGLSHHIASHNLA
IKGGFIHIPYSHELAVNHPGKPSMALATMVAAVRSIVHTALTVGEDLTITGGALH
>Mature_215_residues
MDRVLVTGIEPFDGDAINPSWQVAQALAGEQVAGAEVVVRQLACVLGLSNQQLIAAIEELRPKVVICLGLAGGRGEISIE
RVAINLIDARIPDNAGKQPIDIPVVEGGPVGYFSTLPVKAIVHHLRQSGIPAVVSHTAGTYNCNQLFYGLSHHIASHNLA
IKGGFIHIPYSHELAVNHPGKPSMALATMVAAVRSIVHTALTVGEDLTITGGALH

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 22582; Mature: 22582

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS01333 PYRASE_GLU ; PS01334 PYRASE_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRVLVTGIEPFDGDAINPSWQVAQALAGEQVAGAEVVVRQLACVLGLSNQQLIAAIEEL
CCCEEEECCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHC
RPKVVICLGLAGGRGEISIERVAINLIDARIPDNAGKQPIDIPVVEGGPVGYFSTLPVKA
CCEEEEEEEECCCCCCEEEEEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCHHCCCHHH
IVHHLRQSGIPAVVSHTAGTYNCNQLFYGLSHHIASHNLAIKGGFIHIPYSHELAVNHPG
HHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCEEEECCEEECCCCCEEEECCCC
KPSMALATMVAAVRSIVHTALTVGEDLTITGGALH
CCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC
>Mature Secondary Structure
MDRVLVTGIEPFDGDAINPSWQVAQALAGEQVAGAEVVVRQLACVLGLSNQQLIAAIEEL
CCCEEEECCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHC
RPKVVICLGLAGGRGEISIERVAINLIDARIPDNAGKQPIDIPVVEGGPVGYFSTLPVKA
CCEEEEEEEECCCCCCEEEEEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCHHCCCHHH
IVHHLRQSGIPAVVSHTAGTYNCNQLFYGLSHHIASHNLAIKGGFIHIPYSHELAVNHPG
HHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCEEEECCEEECCCCCEEEECCCC
KPSMALATMVAAVRSIVHTALTVGEDLTITGGALH
CCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]