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The map label for this gene is yeaD [H]

Identifier: 157370969

GI number: 157370969

Start: 3005737

End: 3006612

Strand: Direct

Name: yeaD [H]

Synonym: Spro_2729

Alternate gene names: 157370969

Gene position: 3005737-3006612 (Clockwise)

Preceding gene: 157370968

Following gene: 157370971

Centisome position: 55.16

GC content: 55.59

Gene sequence:

>876_bases
ATGAACGAAAAGATTTTCACCCTACCCGTTACCGAACAAATTTCCCCTTTTATCAGTCAGCGCCAGCTCGATGAACTGCC
TGTCGTAGTGGTTTCCCATCCGAAAGTGCGTGCCGCTATCTCACTTCAGGGTGCGCATCTGTTGGCCTGGCAACCTAGCG
GTGAAAAACCGGTTATTTGGCTGAGCAACAACACCCCCTTTAAAAAGGGCAATGCCATCCGTGGCGGCGTGCCTATCTGC
TGGCCCTGGTTTGGCCCGGTAGCAAAACCTTCACACGGTTTCGCACGCAATCAGCCGTGGACTCTGACCGCGCATGATGA
AGACGACAACGGCGTTATTCTGACCTTCACGCTGAAAGACAATGAGCAGACCCGCAGCCTGTGGCCACATGCCTTTACGC
TGATTGCCCGCTTCAAACTGGGTGAGGAATGCGAAATAGAGCTGGAATCCCACGGCGACTATCAGGCGACCGCGGCGTTG
CACACCTACTTCCAGATCGGTGATATCGGGCAGGTTAAAGTTGCCGGGCTCGGCGAACCCTATATCGATAAGGTTGCCGG
CGGCGCAGAAGCTCGCCAGGTGGGTGACGTGACCTTTGTCGGCCAGACCGACCGGGTTTATACCCAGCCGGACGCCTTCA
GTCTGATCAAAGATGCGGCGCAACAACGCACCATTGAGGTTCATCACCATCACATGAGTGACGTGATTGCCTGGAATCCC
GGCGTGGAGCTTTCTTGCAGCATGGCGGATATGCCAAATGACGGTTATAAAACCATGGTTTGCGTAGAAACCGGTCGCGT
CAGTAAACCCCTGGTGGCAGCCGGTGAACAACCGGCCCGGCTGGCAGTGACCTTCCGTGTTCGTAACAACGGCTGA

Upstream 100 bases:

>100_bases
TCGCTCACATCTCCAAATAATGGATTGATGTTAAGCTGATGATGAGGGTGACATTTTTGTCACCCTTTTTTTGTTTCTAC
GGCGAACAAAAGGCAACCCG

Downstream 100 bases:

>100_bases
TCCCTTTTAAGTGCAGTAAAGACTTGCTGCGCTACAGATGTGCAAAAGGGGCGCCAGCGCCCCTTTATGATGCCTACATT
GCACAACATTGGTGCAGGCT

Product: aldose 1-epimerase

Products: NA

Alternate protein names: Putative D-hexose-6-phosphate mutarotase; Unknown protein from 2D-page spots T26/PR37 [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MNEKIFTLPVTEQISPFISQRQLDELPVVVVSHPKVRAAISLQGAHLLAWQPSGEKPVIWLSNNTPFKKGNAIRGGVPIC
WPWFGPVAKPSHGFARNQPWTLTAHDEDDNGVILTFTLKDNEQTRSLWPHAFTLIARFKLGEECEIELESHGDYQATAAL
HTYFQIGDIGQVKVAGLGEPYIDKVAGGAEARQVGDVTFVGQTDRVYTQPDAFSLIKDAAQQRTIEVHHHHMSDVIAWNP
GVELSCSMADMPNDGYKTMVCVETGRVSKPLVAAGEQPARLAVTFRVRNNG

Sequences:

>Translated_291_residues
MNEKIFTLPVTEQISPFISQRQLDELPVVVVSHPKVRAAISLQGAHLLAWQPSGEKPVIWLSNNTPFKKGNAIRGGVPIC
WPWFGPVAKPSHGFARNQPWTLTAHDEDDNGVILTFTLKDNEQTRSLWPHAFTLIARFKLGEECEIELESHGDYQATAAL
HTYFQIGDIGQVKVAGLGEPYIDKVAGGAEARQVGDVTFVGQTDRVYTQPDAFSLIKDAAQQRTIEVHHHHMSDVIAWNP
GVELSCSMADMPNDGYKTMVCVETGRVSKPLVAAGEQPARLAVTFRVRNNG
>Mature_291_residues
MNEKIFTLPVTEQISPFISQRQLDELPVVVVSHPKVRAAISLQGAHLLAWQPSGEKPVIWLSNNTPFKKGNAIRGGVPIC
WPWFGPVAKPSHGFARNQPWTLTAHDEDDNGVILTFTLKDNEQTRSLWPHAFTLIARFKLGEECEIELESHGDYQATAAL
HTYFQIGDIGQVKVAGLGEPYIDKVAGGAEARQVGDVTFVGQTDRVYTQPDAFSLIKDAAQQRTIEVHHHHMSDVIAWNP
GVELSCSMADMPNDGYKTMVCVETGRVSKPLVAAGEQPARLAVTFRVRNNG

Specific function: Unknown

COG id: COG0676

COG function: function code G; Uncharacterized enzymes related to aldose 1-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glucose-6-phosphate 1-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI87081973, Length=291, Percent_Identity=57.7319587628866, Blast_Score=355, Evalue=1e-99,
Organism=Saccharomyces cerevisiae, GI6323746, Length=263, Percent_Identity=30.0380228136882, Blast_Score=105, Evalue=7e-24,
Organism=Drosophila melanogaster, GI19921284, Length=249, Percent_Identity=32.5301204819277, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28574481, Length=164, Percent_Identity=31.0975609756098, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008183
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.15 [H]

Molecular weight: Translated: 32100; Mature: 32100

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEKIFTLPVTEQISPFISQRQLDELPVVVVSHPKVRAAISLQGAHLLAWQPSGEKPVIW
CCCEEEEEECHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCEEEEECCCCCCCEEE
LSNNTPFKKGNAIRGGVPICWPWFGPVAKPSHGFARNQPWTLTAHDEDDNGVILTFTLKD
ECCCCCCCCCCEEECCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECC
NEQTRSLWPHAFTLIARFKLGEECEIELESHGDYQATAALHTYFQIGDIGQVKVAGLGEP
CCCHHHHCHHHEEHHHHHCCCCEEEEEECCCCCEEEEEEEEEEEEECCCCEEEEEECCCH
YIDKVAGGAEARQVGDVTFVGQTDRVYTQPDAFSLIKDAAQQRTIEVHHHHMSDVIAWNP
HHHHHCCCCCHHCCCCEEEECCCCCEEECCCHHHHHHHHHHHCEEEEEECCCCCEEEECC
GVELSCSMADMPNDGYKTMVCVETGRVSKPLVAAGEQPARLAVTFRVRNNG
CCEEEEEECCCCCCCCEEEEEEECCCCCCCCEECCCCCCEEEEEEEEECCC
>Mature Secondary Structure
MNEKIFTLPVTEQISPFISQRQLDELPVVVVSHPKVRAAISLQGAHLLAWQPSGEKPVIW
CCCEEEEEECHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCEEEEECCCCCCCEEE
LSNNTPFKKGNAIRGGVPICWPWFGPVAKPSHGFARNQPWTLTAHDEDDNGVILTFTLKD
ECCCCCCCCCCEEECCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECC
NEQTRSLWPHAFTLIARFKLGEECEIELESHGDYQATAALHTYFQIGDIGQVKVAGLGEP
CCCHHHHCHHHEEHHHHHCCCCEEEEEECCCCCEEEEEEEEEEEEECCCCEEEEEECCCH
YIDKVAGGAEARQVGDVTFVGQTDRVYTQPDAFSLIKDAAQQRTIEVHHHHMSDVIAWNP
HHHHHCCCCCHHCCCCEEEECCCCCEEECCCHHHHHHHHHHHCEEEEEECCCCCEEEECC
GVELSCSMADMPNDGYKTMVCVETGRVSKPLVAAGEQPARLAVTFRVRNNG
CCEEEEEECCCCCCCCEEEEEEECCCCCCCCEECCCCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 10493123 [H]