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The map label for this gene is nudG [H]

Identifier: 157370956

GI number: 157370956

Start: 2992738

End: 2993139

Strand: Direct

Name: nudG [H]

Synonym: Spro_2716

Alternate gene names: 157370956

Gene position: 2992738-2993139 (Clockwise)

Preceding gene: 157370955

Following gene: 157370962

Centisome position: 54.92

GC content: 55.47

Gene sequence:

>402_bases
ATGAAAATTATCGATGTCGTCGCCGCCATCATTGAAAGAAATGGCAAAATTCTTTTGGCGCAGCGTAATGCTGACAGCGA
TCAGGCCGGATTGTGGGAGTTTCCCGGCGGCAAGGTTGAGGCAGGCGAGAGCCAGCCACAGGCACTGGCGCGTGAACTGG
ACGAAGAGTTGGGAATTGTGGCCAGTGTTGGCCGCTATGTCGCCAGCAACCAGTGGCAACAGAGTGAGCGAATGATCCGG
CTACATGCCTGGCAGGTTGATACCTTTAGCGGTGAATTACAAAACCGCTGCCATTCGGATTTTGTCTGGTTGGCGCCGGA
GCAGGCGTTTGACTATCCCCTGGCCCCGGCGGACGTACCGCTATTAACCGCCTATATTAGCGCATTGCAGGCGGAAGCCT
GA

Upstream 100 bases:

>100_bases
CGGGATGGAAAAACCGTCGGATCACGCGCCAGTCTGGGCGGAATTCTCACTGTAATTGACCCAACCCCGGCCATTGCCGG
GGTTTTGCTATGTGGTACCT

Downstream 100 bases:

>100_bases
GTTACAGCGTCACTTCTTCAGACGCACCCAGATTAACGGATTAGTCCCTACCACGTTGGGGTCGCGTACGCACTGCAACG
CTTCCCCTTCCACCTTGAGA

Product: pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MKIIDVVAAIIERNGKILLAQRNADSDQAGLWEFPGGKVEAGESQPQALARELDEELGIVASVGRYVASNQWQQSERMIR
LHAWQVDTFSGELQNRCHSDFVWLAPEQAFDYPLAPADVPLLTAYISALQAEA

Sequences:

>Translated_133_residues
MKIIDVVAAIIERNGKILLAQRNADSDQAGLWEFPGGKVEAGESQPQALARELDEELGIVASVGRYVASNQWQQSERMIR
LHAWQVDTFSGELQNRCHSDFVWLAPEQAFDYPLAPADVPLLTAYISALQAEA
>Mature_133_residues
MKIIDVVAAIIERNGKILLAQRNADSDQAGLWEFPGGKVEAGESQPQALARELDEELGIVASVGRYVASNQWQQSERMIR
LHAWQVDTFSGELQNRCHSDFVWLAPEQAFDYPLAPADVPLLTAYISALQAEA

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=127, Percent_Identity=66.9291338582677, Blast_Score=169, Evalue=8e-44,
Organism=Escherichia coli, GI1786288, Length=125, Percent_Identity=34.4, Blast_Score=64, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 14723; Mature: 14723

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIDVVAAIIERNGKILLAQRNADSDQAGLWEFPGGKVEAGESQPQALARELDEELGIV
CHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEECCCCCEECCCCCHHHHHHHHHHHHHHH
ASVGRYVASNQWQQSERMIRLHAWQVDTFSGELQNRCHSDFVWLAPEQAFDYPLAPADVP
HHHHHHHHCCCHHHHHHEEHHHEEECCCCCHHHHHHHCCCEEEECCHHHCCCCCCCCCHH
LLTAYISALQAEA
HHHHHHHHHHCCC
>Mature Secondary Structure
MKIIDVVAAIIERNGKILLAQRNADSDQAGLWEFPGGKVEAGESQPQALARELDEELGIV
CHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEECCCCCEECCCCCHHHHHHHHHHHHHHH
ASVGRYVASNQWQQSERMIRLHAWQVDTFSGELQNRCHSDFVWLAPEQAFDYPLAPADVP
HHHHHHHHCCCHHHHHHEEHHHEEECCCCCHHHHHHHCCCEEEECCHHHCCCCCCCCCHH
LLTAYISALQAEA
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]