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The map label for this gene is yciA [H]

Identifier: 157370918

GI number: 157370918

Start: 2948226

End: 2948654

Strand: Direct

Name: yciA [H]

Synonym: Spro_2678

Alternate gene names: 157370918

Gene position: 2948226-2948654 (Clockwise)

Preceding gene: 157370917

Following gene: 157370919

Centisome position: 54.11

GC content: 56.18

Gene sequence:

>429_bases
ATGACTCAACAACGACCTTTACCCAGTGGCGAAATGGTGCTGCGAACGCTGGCGATGCCGGCAGATACCAATGCCAACGG
CGATATTTTTGGCGGCTGGCTGATGTCGCAGATGGATATCGGCGGCGCTATTCAGGCCAAAGAAATTGCCGAAGGCCGCG
TAGTCACCGTGCGTGTGGATGGCATGACCTTCCTGAAGCCGGTCGCGGTAGGTGACGTGGTATGTTGCTACGCGCACTGT
ATCCGTACCGGACGCAGCTCGATCACCATCAATATCGAAGTGTGGGTCAAGAAAGTGTCTTCCGCCCCTATCGGCCAGCG
CTATCGCGCCACCGAAGCGGTGTTTACCTATGTTGCCGTAGACGATGAAGGCAATTCACGCGCCCTGCCCGATGGCAAGA
TGAACTTCCGCGTCGGATTCGAAGAATAA

Upstream 100 bases:

>100_bases
CATGCCGGAAGAACAGAAAAAATAGTTACAAAATTGTTAATGCCCGTGGCCTTTGCTACGGGCAGTATAGTGAAATCCCT
TCTTTGATAAGCAGACAGCT

Downstream 100 bases:

>100_bases
GCCTTAGCGCCAGGATTCTTTTTCAAAAAGCCCGATGTGACCCATCGGGTTTTTTTTATTGATGCTGATTACCCGGTGTC
GCAATACCCAGTTTCGATAA

Product: acyl-CoA thioester hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MTQQRPLPSGEMVLRTLAMPADTNANGDIFGGWLMSQMDIGGAIQAKEIAEGRVVTVRVDGMTFLKPVAVGDVVCCYAHC
IRTGRSSITINIEVWVKKVSSAPIGQRYRATEAVFTYVAVDDEGNSRALPDGKMNFRVGFEE

Sequences:

>Translated_142_residues
MTQQRPLPSGEMVLRTLAMPADTNANGDIFGGWLMSQMDIGGAIQAKEIAEGRVVTVRVDGMTFLKPVAVGDVVCCYAHC
IRTGRSSITINIEVWVKKVSSAPIGQRYRATEAVFTYVAVDDEGNSRALPDGKMNFRVGFEE
>Mature_141_residues
TQQRPLPSGEMVLRTLAMPADTNANGDIFGGWLMSQMDIGGAIQAKEIAEGRVVTVRVDGMTFLKPVAVGDVVCCYAHCI
RTGRSSITINIEVWVKKVSSAPIGQRYRATEAVFTYVAVDDEGNSRALPDGKMNFRVGFEE

Specific function: Catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA [H]

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1787506, Length=130, Percent_Identity=77.6923076923077, Blast_Score=216, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 15457; Mature: 15326

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQRPLPSGEMVLRTLAMPADTNANGDIFGGWLMSQMDIGGAIQAKEIAEGRVVTVRVD
CCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEHEEEECCCCCCCEEEEECCCCCEEEEEEC
GMTFLKPVAVGDVVCCYAHCIRTGRSSITINIEVWVKKVSSAPIGQRYRATEAVFTYVAV
CEEEECHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCCCCCCEEEEEEEEE
DDEGNSRALPDGKMNFRVGFEE
ECCCCCCCCCCCCEEEEEECCC
>Mature Secondary Structure 
TQQRPLPSGEMVLRTLAMPADTNANGDIFGGWLMSQMDIGGAIQAKEIAEGRVVTVRVD
CCCCCCCCHHHHHHHHCCCCCCCCCCCEEEHEEEECCCCCCCEEEEECCCCCEEEEEEC
GMTFLKPVAVGDVVCCYAHCIRTGRSSITINIEVWVKKVSSAPIGQRYRATEAVFTYVAV
CEEEECHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCCCCCCEEEEEEEEE
DDEGNSRALPDGKMNFRVGFEE
ECCCCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]