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The map label for this gene is rstB [H]

Identifier: 157370831

GI number: 157370831

Start: 2848666

End: 2849970

Strand: Direct

Name: rstB [H]

Synonym: Spro_2591

Alternate gene names: 157370831

Gene position: 2848666-2849970 (Clockwise)

Preceding gene: 157370830

Following gene: 157370832

Centisome position: 52.28

GC content: 56.4

Gene sequence:

>1305_bases
ATGAGAAAGCTCTTTGTGCAGTTCTTCCTGCTGCTTTTCGTGTGTTTCCTGGTGATGGCAATGCTGGTGGGGTTGGTGTA
CAAAGTCACCGCCGAACGCGCCGGCCGCCAGTCGATGGACGATCTGATGAAAAGCTCGCTGTACCTGATGCGCAGCGAAC
TGCGGGAAATTCCGCTCAAAGACTGGAACAAGACCATCGCCACGCTGGACTTGAATCTGTCGTTTAAGCTGCACATCGAG
CCGCTGGGCAAACAGGATCTGAGCGAAGATTTGAAAAAACGGCTGCGTCTGGGGGAGATTATCGCCCTCGACGATCAATA
CACCTTTATGCAGCGTATCCCGCGCAGTCACTACGTGCTGGTGGTCGGGCCGATCCCTTATCTGTTCTATCTGCATCAAA
TGCGGCTGCTGGATTTGGCGCTGCTGGTGTTTATCGGCATGTCGCTGGCGCTGCCGGTATTTCTGTGGATGCGTCCGCAC
TGGCAGGACTTGCTCAAGCTGGAAAACGCGGCTCAGCGCCTCGGTGCCGGGCATCTGGATGAGCGAACCCATTTCGACCC
TACCTCCAGCCTGAATCGGCTTGGCGTAGCCTTTAACCAGATGGCGGATAACGTCAATACGCTGATCGCCAGCAAGAAAC
AGCTGATAGACGGTATCGCCCATGAACTGCGCACTCCGCTGGTACGGCTGCGTTACCGCCTGGCGATGAGCGATAACCTT
TCCGAGAGTGAACAGCAGGCGCTGAACCGCGATATCGGTCAGTTGGAGTCACTGATCGACGAACTGCTGACCTATGCACG
ATTGGACCGTCCGCAGGTCGCACTCAATATAGAACCGCTGGATTTGCCCAAATGGCTGGAGGACAAGGCTGACGACCTGC
GCCTGATCCACCCGGAACGTGAAATCGAATTGAACATCCCGCACGTCGGTGATTTTGGCGGCGTCGATTTACGGCTAATG
GAGCGGGTGCTGGATAATCTGGTGAACAATGCGCTGCGTTATAGTGAGCAACGCTTGCGCATCGGCCTGTGGTTTGACGG
CGACAACGCCTGCCTGCAGGTAGAAGACGATGGGCCAGGTATTCCACCGGAAGAACGTGAGCGGGTATTCGAGCCCTTTG
TACGTCTCGATCCCAGCCGCGATCGCGCGACCGGCGGCTGTGGCCTGGGTTTGGCGATTGTTCATTCGATTGCCGTGGCC
TACCAGGGCCAGGTCTACGTTGACGCCAGCTCTCTCGGTGGTGCCAGCTTCCGATTCTGTTGGCCGCTAAAGCCCACTTT
CAATTTAAAAGCAGACCCGGTGTAA

Upstream 100 bases:

>100_bases
GCCGCAAACTGTACGACAATGCCCTGGAACCCTTCCGCGTCAAAACCGTGCGTAATAAAGGTTACCTGTTCGCTCCGAAT
GCCTGGGAGTTCGTGCAGCA

Downstream 100 bases:

>100_bases
CCCCGTTTACGTGGCAGCATAAAAACGCGAAACAGTGATCCGGTTTACAAAAAATGGAGCTAAACGATGACATCTGCACA
TTCCCCTTCTTCTTACGACG

Product: sensor protein RstB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MRKLFVQFFLLLFVCFLVMAMLVGLVYKVTAERAGRQSMDDLMKSSLYLMRSELREIPLKDWNKTIATLDLNLSFKLHIE
PLGKQDLSEDLKKRLRLGEIIALDDQYTFMQRIPRSHYVLVVGPIPYLFYLHQMRLLDLALLVFIGMSLALPVFLWMRPH
WQDLLKLENAAQRLGAGHLDERTHFDPTSSLNRLGVAFNQMADNVNTLIASKKQLIDGIAHELRTPLVRLRYRLAMSDNL
SESEQQALNRDIGQLESLIDELLTYARLDRPQVALNIEPLDLPKWLEDKADDLRLIHPEREIELNIPHVGDFGGVDLRLM
ERVLDNLVNNALRYSEQRLRIGLWFDGDNACLQVEDDGPGIPPEERERVFEPFVRLDPSRDRATGGCGLGLAIVHSIAVA
YQGQVYVDASSLGGASFRFCWPLKPTFNLKADPV

Sequences:

>Translated_434_residues
MRKLFVQFFLLLFVCFLVMAMLVGLVYKVTAERAGRQSMDDLMKSSLYLMRSELREIPLKDWNKTIATLDLNLSFKLHIE
PLGKQDLSEDLKKRLRLGEIIALDDQYTFMQRIPRSHYVLVVGPIPYLFYLHQMRLLDLALLVFIGMSLALPVFLWMRPH
WQDLLKLENAAQRLGAGHLDERTHFDPTSSLNRLGVAFNQMADNVNTLIASKKQLIDGIAHELRTPLVRLRYRLAMSDNL
SESEQQALNRDIGQLESLIDELLTYARLDRPQVALNIEPLDLPKWLEDKADDLRLIHPEREIELNIPHVGDFGGVDLRLM
ERVLDNLVNNALRYSEQRLRIGLWFDGDNACLQVEDDGPGIPPEERERVFEPFVRLDPSRDRATGGCGLGLAIVHSIAVA
YQGQVYVDASSLGGASFRFCWPLKPTFNLKADPV
>Mature_434_residues
MRKLFVQFFLLLFVCFLVMAMLVGLVYKVTAERAGRQSMDDLMKSSLYLMRSELREIPLKDWNKTIATLDLNLSFKLHIE
PLGKQDLSEDLKKRLRLGEIIALDDQYTFMQRIPRSHYVLVVGPIPYLFYLHQMRLLDLALLVFIGMSLALPVFLWMRPH
WQDLLKLENAAQRLGAGHLDERTHFDPTSSLNRLGVAFNQMADNVNTLIASKKQLIDGIAHELRTPLVRLRYRLAMSDNL
SESEQQALNRDIGQLESLIDELLTYARLDRPQVALNIEPLDLPKWLEDKADDLRLIHPEREIELNIPHVGDFGGVDLRLM
ERVLDNLVNNALRYSEQRLRIGLWFDGDNACLQVEDDGPGIPPEERERVFEPFVRLDPSRDRATGGCGLGLAIVHSIAVA
YQGQVYVDASSLGGASFRFCWPLKPTFNLKADPV

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=423, Percent_Identity=69.9763593380615, Blast_Score=612, Evalue=1e-176,
Organism=Escherichia coli, GI1790346, Length=264, Percent_Identity=33.7121212121212, Blast_Score=138, Evalue=9e-34,
Organism=Escherichia coli, GI1789808, Length=278, Percent_Identity=31.294964028777, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788393, Length=270, Percent_Identity=32.2222222222222, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786783, Length=310, Percent_Identity=29.0322580645161, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=27.3127753303965, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786912, Length=222, Percent_Identity=31.5315315315315, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788279, Length=239, Percent_Identity=31.7991631799163, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789403, Length=452, Percent_Identity=26.1061946902655, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790551, Length=218, Percent_Identity=30.2752293577982, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87082128, Length=292, Percent_Identity=27.0547945205479, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI145693157, Length=259, Percent_Identity=26.2548262548263, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=223, Percent_Identity=26.457399103139, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789149, Length=224, Percent_Identity=28.125, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788549, Length=243, Percent_Identity=26.7489711934156, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081816, Length=252, Percent_Identity=26.5873015873016, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787374, Length=321, Percent_Identity=25.5451713395639, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49656; Mature: 49656

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLFVQFFLLLFVCFLVMAMLVGLVYKVTAERAGRQSMDDLMKSSLYLMRSELREIPLK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCH
DWNKTIATLDLNLSFKLHIEPLGKQDLSEDLKKRLRLGEIIALDDQYTFMQRIPRSHYVL
HCCCEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCEEE
VVGPIPYLFYLHQMRLLDLALLVFIGMSLALPVFLWMRPHWQDLLKLENAAQRLGAGHLD
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
ERTHFDPTSSLNRLGVAFNQMADNVNTLIASKKQLIDGIAHELRTPLVRLRYRLAMSDNL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SESEQQALNRDIGQLESLIDELLTYARLDRPQVALNIEPLDLPKWLEDKADDLRLIHPER
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHCCCCCEEEECCCC
EIELNIPHVGDFGGVDLRLMERVLDNLVNNALRYSEQRLRIGLWFDGDNACLQVEDDGPG
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCCC
IPPEERERVFEPFVRLDPSRDRATGGCGLGLAIVHSIAVAYQGQVYVDASSLGGASFRFC
CCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEE
WPLKPTFNLKADPV
ECCCCCCCCCCCCC
>Mature Secondary Structure
MRKLFVQFFLLLFVCFLVMAMLVGLVYKVTAERAGRQSMDDLMKSSLYLMRSELREIPLK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCH
DWNKTIATLDLNLSFKLHIEPLGKQDLSEDLKKRLRLGEIIALDDQYTFMQRIPRSHYVL
HCCCEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCEEE
VVGPIPYLFYLHQMRLLDLALLVFIGMSLALPVFLWMRPHWQDLLKLENAAQRLGAGHLD
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
ERTHFDPTSSLNRLGVAFNQMADNVNTLIASKKQLIDGIAHELRTPLVRLRYRLAMSDNL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SESEQQALNRDIGQLESLIDELLTYARLDRPQVALNIEPLDLPKWLEDKADDLRLIHPER
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHCCCCCEEEECCCC
EIELNIPHVGDFGGVDLRLMERVLDNLVNNALRYSEQRLRIGLWFDGDNACLQVEDDGPG
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCCC
IPPEERERVFEPFVRLDPSRDRATGGCGLGLAIVHSIAVAYQGQVYVDASSLGGASFRFC
CCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEE
WPLKPTFNLKADPV
ECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]