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The map label for this gene is malE [C]

Identifier: 157370811

GI number: 157370811

Start: 2827337

End: 2828590

Strand: Direct

Name: malE [C]

Synonym: Spro_2571

Alternate gene names: 157370811

Gene position: 2827337-2828590 (Clockwise)

Preceding gene: 157370806

Following gene: 157370812

Centisome position: 51.89

GC content: 51.52

Gene sequence:

>1254_bases
ATGTCACCGATAAAAAATACCGGCCGTCTTCTGGCGCACTCTGCCATTGCGGTTGCATTATTATTGCCGACCATGTTATA
TGCCGCCGATCAAATAACCCTGCGTTACGCCGTGTGGGACAGGAATCAATTACCTTCCGAGCAGGAGATTGCCAAAAGAT
TTGAAAAAGAAAACCCTAACATTAAAATCGCCATAGAATTAACGCCGTCGGCACAATACTTCGTTAAATTAGATTCCGCC
GCCGCAGGGGGTGTCGCGCCAGATATATTCTGGATAAACATGCCTTATTTCGTTCAATACGCCAAAAATGGCATTATGCA
ACCCTTAACGCCGTATATTACCGGCAGCAGCGTGCAATTAAATAATATCGTCGCCAGTTCGGTTAAAGCCTATCAGTATG
ATGGGCAGCAAATGGCCATCCCCCGCGACGTTGACTCAATCGCCGTGTGGTACAACAAAAAATTATTCGACCAGGCCGGC
GTCAGCTACCCGACCAACGACTGGAGCTGGGATGACCTGAAAAACAAAGCCACCGCGCTGAAAACCGGCTTGAAGGGCAG
TGCCTTCCCGCTGGTGATGGATCTGAGCATTGACGGGCAGGACAGCTATATGAACCTGCTGTTCCAAAACGGCAACCACA
TAGTCCCGAAAGACGGTCAACCCACCGACATCGCTAACGATAAATCCATCTGGGTCTATCAACAGCTGCAATCCATGATG
AAAGATGGCTTGATGCCCAGCGCCCAACAGATGAGCGAAGTCAAAACCGAAAACATCTTCCAGTCCAACCGTGCGGCGAT
GGTGTATGCCGGCTCATGGCTGGCCGCCCCGTTCGCCAACAATCCGCTGATCAACGACCATATCGGCGTGGTCATGATGC
CGAAAATCGAGCGCCAGTCCGGCGTGGCGCACAGCCTGGCATTTGCCATGTCCGCCAACAGCGCCCACAAGCAGGAAGCC
TGGAAATACATCGAATTTATGAGCTCCGAAGCCTCGCAGACCGAGTTGGCAAAAGCGGTGATCCCGGCCAACAAACTGGC
GGCCAAAGCCTGGGCGGCGGAGATCAAAAAAGTCGATGTCACACCTTATATTGACACCCTCAACGTGACCGAAGCCTACC
CCACAGCCGGTACCAATACGCCGAAATGGCAAAACATGTGGATTGCCAGCCTAAAGAAAATCTTTATGGGTGCGGACGCC
AAAGTCGAGATGGACAAATCGGTCAAGAAGATCGAACGCGTAATGGAGCAGTAA

Upstream 100 bases:

>100_bases
TTTTTGGGCAGATCGGGGCGTATTGACACATTGAAAGTTAAGGGATAGAAAGAATTCACGTTACGAAAATATTTATTCGT
CGTTCACCGAGGGGAAAACA

Downstream 100 bases:

>100_bases
TCACCCCGAGCCGGTAGCGCCTGCCCGAAGGCGCACCGGCTGCGGAATACCGCAGAGCAGTTACAGGTGAGGAAAGGCAA
CATGTCGCTGGCAGAAAGCT

Product: extracellular solute-binding protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSPIKNTGRLLAHSAIAVALLLPTMLYAADQITLRYAVWDRNQLPSEQEIAKRFEKENPNIKIAIELTPSAQYFVKLDSA
AAGGVAPDIFWINMPYFVQYAKNGIMQPLTPYITGSSVQLNNIVASSVKAYQYDGQQMAIPRDVDSIAVWYNKKLFDQAG
VSYPTNDWSWDDLKNKATALKTGLKGSAFPLVMDLSIDGQDSYMNLLFQNGNHIVPKDGQPTDIANDKSIWVYQQLQSMM
KDGLMPSAQQMSEVKTENIFQSNRAAMVYAGSWLAAPFANNPLINDHIGVVMMPKIERQSGVAHSLAFAMSANSAHKQEA
WKYIEFMSSEASQTELAKAVIPANKLAAKAWAAEIKKVDVTPYIDTLNVTEAYPTAGTNTPKWQNMWIASLKKIFMGADA
KVEMDKSVKKIERVMEQ

Sequences:

>Translated_417_residues
MSPIKNTGRLLAHSAIAVALLLPTMLYAADQITLRYAVWDRNQLPSEQEIAKRFEKENPNIKIAIELTPSAQYFVKLDSA
AAGGVAPDIFWINMPYFVQYAKNGIMQPLTPYITGSSVQLNNIVASSVKAYQYDGQQMAIPRDVDSIAVWYNKKLFDQAG
VSYPTNDWSWDDLKNKATALKTGLKGSAFPLVMDLSIDGQDSYMNLLFQNGNHIVPKDGQPTDIANDKSIWVYQQLQSMM
KDGLMPSAQQMSEVKTENIFQSNRAAMVYAGSWLAAPFANNPLINDHIGVVMMPKIERQSGVAHSLAFAMSANSAHKQEA
WKYIEFMSSEASQTELAKAVIPANKLAAKAWAAEIKKVDVTPYIDTLNVTEAYPTAGTNTPKWQNMWIASLKKIFMGADA
KVEMDKSVKKIERVMEQ
>Mature_416_residues
SPIKNTGRLLAHSAIAVALLLPTMLYAADQITLRYAVWDRNQLPSEQEIAKRFEKENPNIKIAIELTPSAQYFVKLDSAA
AGGVAPDIFWINMPYFVQYAKNGIMQPLTPYITGSSVQLNNIVASSVKAYQYDGQQMAIPRDVDSIAVWYNKKLFDQAGV
SYPTNDWSWDDLKNKATALKTGLKGSAFPLVMDLSIDGQDSYMNLLFQNGNHIVPKDGQPTDIANDKSIWVYQQLQSMMK
DGLMPSAQQMSEVKTENIFQSNRAAMVYAGSWLAAPFANNPLINDHIGVVMMPKIERQSGVAHSLAFAMSANSAHKQEAW
KYIEFMSSEASQTELAKAVIPANKLAAKAWAAEIKKVDVTPYIDTLNVTEAYPTAGTNTPKWQNMWIASLKKIFMGADAK
VEMDKSVKKIERVMEQ

Specific function: Probably part of an ABC transporter complex [H]

COG id: COG1653

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 720 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059
- InterPro:   IPR006061 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 46364; Mature: 46232

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS00110 PYRUVATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPIKNTGRLLAHSAIAVALLLPTMLYAADQITLRYAVWDRNQLPSEQEIAKRFEKENPN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCC
IKIAIELTPSAQYFVKLDSAAAGGVAPDIFWINMPYFVQYAKNGIMQPLTPYITGSSVQL
EEEEEEECCCCEEEEEECCCCCCCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCCCCEEE
NNIVASSVKAYQYDGQQMAIPRDVDSIAVWYNKKLFDQAGVSYPTNDWSWDDLKNKATAL
HHHHHHHHHHEEECCCEEECCCCCCCEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
KTGLKGSAFPLVMDLSIDGQDSYMNLLFQNGNHIVPKDGQPTDIANDKSIWVYQQLQSMM
HCCCCCCCCEEEEEEEECCCHHHHHHEEECCCEECCCCCCCCCCCCCCCCHHHHHHHHHH
KDGLMPSAQQMSEVKTENIFQSNRAAMVYAGSWLAAPFANNPLINDHIGVVMMPKIERQS
HCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCEEECCCCCCCEECCCCCEEEECCCHHHC
GVAHSLAFAMSANSAHKQEAWKYIEFMSSEASQTELAKAVIPANKLAAKAWAAEIKKVDV
CHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHEECC
TPYIDTLNVTEAYPTAGTNTPKWQNMWIASLKKIFMGADAKVEMDKSVKKIERVMEQ
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPIKNTGRLLAHSAIAVALLLPTMLYAADQITLRYAVWDRNQLPSEQEIAKRFEKENPN
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCC
IKIAIELTPSAQYFVKLDSAAAGGVAPDIFWINMPYFVQYAKNGIMQPLTPYITGSSVQL
EEEEEEECCCCEEEEEECCCCCCCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCCCCEEE
NNIVASSVKAYQYDGQQMAIPRDVDSIAVWYNKKLFDQAGVSYPTNDWSWDDLKNKATAL
HHHHHHHHHHEEECCCEEECCCCCCCEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
KTGLKGSAFPLVMDLSIDGQDSYMNLLFQNGNHIVPKDGQPTDIANDKSIWVYQQLQSMM
HCCCCCCCCEEEEEEEECCCHHHHHHEEECCCEECCCCCCCCCCCCCCCCHHHHHHHHHH
KDGLMPSAQQMSEVKTENIFQSNRAAMVYAGSWLAAPFANNPLINDHIGVVMMPKIERQS
HCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCEEECCCCCCCEECCCCCEEEECCCHHHC
GVAHSLAFAMSANSAHKQEAWKYIEFMSSEASQTELAKAVIPANKLAAKAWAAEIKKVDV
CHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHEECC
TPYIDTLNVTEAYPTAGTNTPKWQNMWIASLKKIFMGADAKVEMDKSVKKIERVMEQ
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA