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The map label for this gene is ttuB [H]

Identifier: 157370738

GI number: 157370738

Start: 2742592

End: 2743899

Strand: Direct

Name: ttuB [H]

Synonym: Spro_2498

Alternate gene names: 157370738

Gene position: 2742592-2743899 (Clockwise)

Preceding gene: 157370737

Following gene: 157370739

Centisome position: 50.33

GC content: 58.1

Gene sequence:

>1308_bases
ATGGATAATAAAATACCCAACACCCGCTGGCTGCGGGTTATTGCCCCGATCCTGATCGCCTGCATTATTTCCTTTATGGA
CCGGGTCAATATCAGTTTTGCCCTGCCCGGCGGTATGGAAAGTGATTTGGGCATCACCAGCCAGATGGCCGGTTTGGCCA
GCGGCATCTTCTTTATCGGCTATCTGTTTTTGCAGGTTCCCGGCGGGCGCATTGCGGTTAACGGCAGCGGCAAGCGCTTT
ATTGCCTGGTCACTGTGTGCCTGGGCGGTGGTTTCCGTGGCGACCGGTTTTGTCACTAACCACTATCAACTGCTGATTTT
GCGCTTTGTGTTGGGGATTTCCGAAGGGGGTATGTTGCCGGTGGTGCTGACCATGATCAGCAACTGGTTCCCGGAAAAAG
AACTGGGCCGTGCCAACGCCTTCGTGATGATGTTCGCCCCGCTGGGTGGCATGCTCACCGCCCCCATTTCTGGCGCCATC
ATTAACCAGCTCGACTGGCGCTGGCTGTTTATCCTCGAAGGTTTGCTGTCACTGGTGGTGTTGGCCGTCTGGTGGCTGTT
GATCAGCGATCGGCCGCAGGAAGCGCGCTGGTTACCGGCCCGCGAGCGCGAATATCTGATCACCGAGCTGACGCGCGAAC
GGCAAGCACGCAGCAAAATGCAGCCGGTCAGCAAGGCGCCACTGAGGGACGTATTCCGCAATAAGGGGTTGATGAAGCTG
GTATTGCTGAACTTCTTCTACCAGACCGGTGACTATGGTTACACCCTGTGGTTGCCGACCATTCTGAAAAACCTGACCGG
TGGCAATATGGCCTCGGTCGGTTTCCTGGCCATTTTGCCGTTCGTCGCCACCCTGCTGGGGATTTACCTGATTTCGGTGC
TGACCGATAAAACCGGCAAGCGCCGCCTGTGGGTAATGGTTTCACTGTTCTGCTTCGCCGCTGCGCTGTTGGCCTCGGTG
GTGCTGCGCCATAACGTGGTGGCGGCCTATATCGCATTAGTGGTGTGCGGCTTCTTCCTGAAGGCGGCAACCAGCCCGTT
CTGGTCGATGCCAGGGCGTATCGCTTCGGCGGAGGTCGCCGGTGGCGCGCGCGGTGTGATTAACGGTCTGGGCAATCTGG
GGGGGTTCTGCGGGCCTTATCTGGTCGGTGTGATGATCTACCTGTACGGTCAAAACGTCGCGGTGTGCGCGTTGGCGGTA
TCGCTGATCATCGCCGGTATTATCGCCTGGCGCTTGCCGAGAGAATGTGACCTGACCAGCAGCGAGCCGGCGCATGACCC
ACTGTTGGATAAGGCCAAACGCGCCTGA

Upstream 100 bases:

>100_bases
TGAATAATTAAGCCGTTTCTTTCGAATTTATTATCGCCGTACCACAGAACCTCTTTATTAATTGAGAGGTTCTCCCTGCG
CCTTATAAAGAGAGATCGCC

Downstream 100 bases:

>100_bases
ATAACAACGAAAACCACGAGCGGGCAACGGCAAAATTTGCTATGTTAGCCCGCTCTGATTAAGGTCTGTTGTTACTCGCC
GGATAGGTCTATGTTTACCC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MDNKIPNTRWLRVIAPILIACIISFMDRVNISFALPGGMESDLGITSQMAGLASGIFFIGYLFLQVPGGRIAVNGSGKRF
IAWSLCAWAVVSVATGFVTNHYQLLILRFVLGISEGGMLPVVLTMISNWFPEKELGRANAFVMMFAPLGGMLTAPISGAI
INQLDWRWLFILEGLLSLVVLAVWWLLISDRPQEARWLPAREREYLITELTRERQARSKMQPVSKAPLRDVFRNKGLMKL
VLLNFFYQTGDYGYTLWLPTILKNLTGGNMASVGFLAILPFVATLLGIYLISVLTDKTGKRRLWVMVSLFCFAAALLASV
VLRHNVVAAYIALVVCGFFLKAATSPFWSMPGRIASAEVAGGARGVINGLGNLGGFCGPYLVGVMIYLYGQNVAVCALAV
SLIIAGIIAWRLPRECDLTSSEPAHDPLLDKAKRA

Sequences:

>Translated_435_residues
MDNKIPNTRWLRVIAPILIACIISFMDRVNISFALPGGMESDLGITSQMAGLASGIFFIGYLFLQVPGGRIAVNGSGKRF
IAWSLCAWAVVSVATGFVTNHYQLLILRFVLGISEGGMLPVVLTMISNWFPEKELGRANAFVMMFAPLGGMLTAPISGAI
INQLDWRWLFILEGLLSLVVLAVWWLLISDRPQEARWLPAREREYLITELTRERQARSKMQPVSKAPLRDVFRNKGLMKL
VLLNFFYQTGDYGYTLWLPTILKNLTGGNMASVGFLAILPFVATLLGIYLISVLTDKTGKRRLWVMVSLFCFAAALLASV
VLRHNVVAAYIALVVCGFFLKAATSPFWSMPGRIASAEVAGGARGVINGLGNLGGFCGPYLVGVMIYLYGQNVAVCALAV
SLIIAGIIAWRLPRECDLTSSEPAHDPLLDKAKRA
>Mature_435_residues
MDNKIPNTRWLRVIAPILIACIISFMDRVNISFALPGGMESDLGITSQMAGLASGIFFIGYLFLQVPGGRIAVNGSGKRF
IAWSLCAWAVVSVATGFVTNHYQLLILRFVLGISEGGMLPVVLTMISNWFPEKELGRANAFVMMFAPLGGMLTAPISGAI
INQLDWRWLFILEGLLSLVVLAVWWLLISDRPQEARWLPAREREYLITELTRERQARSKMQPVSKAPLRDVFRNKGLMKL
VLLNFFYQTGDYGYTLWLPTILKNLTGGNMASVGFLAILPFVATLLGIYLISVLTDKTGKRRLWVMVSLFCFAAALLASV
VLRHNVVAAYIALVVCGFFLKAATSPFWSMPGRIASAEVAGGARGVINGLGNLGGFCGPYLVGVMIYLYGQNVAVCALAV
SLIIAGIIAWRLPRECDLTSSEPAHDPLLDKAKRA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=344, Percent_Identity=24.7093023255814, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI9945322, Length=385, Percent_Identity=23.1168831168831, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI9966811, Length=381, Percent_Identity=22.0472440944882, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI148743791, Length=258, Percent_Identity=25.1937984496124, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI21322234, Length=357, Percent_Identity=22.96918767507, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87082071, Length=439, Percent_Identity=29.6127562642369, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI87082320, Length=416, Percent_Identity=25.7211538461538, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1789515, Length=418, Percent_Identity=23.9234449760766, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI2367379, Length=306, Percent_Identity=26.1437908496732, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789152, Length=423, Percent_Identity=23.4042553191489, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI2367193, Length=288, Percent_Identity=25.3472222222222, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1788074, Length=382, Percent_Identity=23.2984293193717, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17552542, Length=350, Percent_Identity=24.8571428571429, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560030, Length=293, Percent_Identity=24.2320819112628, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533556, Length=312, Percent_Identity=24.3589743589744, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533554, Length=312, Percent_Identity=24.3589743589744, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17566884, Length=234, Percent_Identity=25.2136752136752, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI25141318, Length=318, Percent_Identity=22.9559748427673, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI86561091, Length=290, Percent_Identity=22.0689655172414, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25141316, Length=284, Percent_Identity=23.2394366197183, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25141341, Length=240, Percent_Identity=23.3333333333333, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17535049, Length=370, Percent_Identity=23.5135135135135, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321698, Length=343, Percent_Identity=21.5743440233236, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6322025, Length=223, Percent_Identity=23.3183856502242, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322612, Length=203, Percent_Identity=24.1379310344828, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI20130167, Length=399, Percent_Identity=28.0701754385965, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24583789, Length=360, Percent_Identity=23.3333333333333, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24584153, Length=375, Percent_Identity=24.5333333333333, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24641682, Length=369, Percent_Identity=24.9322493224932, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI45550460, Length=295, Percent_Identity=25.0847457627119, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28573708, Length=274, Percent_Identity=25.1824817518248, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28573707, Length=274, Percent_Identity=25.1824817518248, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24653727, Length=385, Percent_Identity=25.974025974026, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24655255, Length=272, Percent_Identity=25.3676470588235, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24580790, Length=227, Percent_Identity=25.5506607929515, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24655271, Length=393, Percent_Identity=21.6284987277354, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI20130135, Length=393, Percent_Identity=21.6284987277354, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI28573299, Length=405, Percent_Identity=25.4320987654321, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24654215, Length=368, Percent_Identity=23.3695652173913, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19922400, Length=368, Percent_Identity=23.3695652173913, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24639764, Length=363, Percent_Identity=23.1404958677686, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221474708, Length=189, Percent_Identity=26.984126984127, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24648416, Length=272, Percent_Identity=20.2205882352941, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356189, Length=272, Percent_Identity=20.2205882352941, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45550364, Length=344, Percent_Identity=22.6744186046512, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20129235, Length=423, Percent_Identity=22.4586288416076, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24658696, Length=218, Percent_Identity=24.7706422018349, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24658666, Length=394, Percent_Identity=21.0659898477157, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47668; Mature: 47668

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNKIPNTRWLRVIAPILIACIISFMDRVNISFALPGGMESDLGITSQMAGLASGIFFIG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
YLFLQVPGGRIAVNGSGKRFIAWSLCAWAVVSVATGFVTNHYQLLILRFVLGISEGGMLP
HHHHCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VVLTMISNWFPEKELGRANAFVMMFAPLGGMLTAPISGAIINQLDWRWLFILEGLLSLVV
HHHHHHHCCCCCHHHCCCCEEEEEECCCCCHHHCCCCHHHHHHCCHHHHHHHHHHHHHHH
LAVWWLLISDRPQEARWLPAREREYLITELTRERQARSKMQPVSKAPLRDVFRNKGLMKL
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHH
VLLNFFYQTGDYGYTLWLPTILKNLTGGNMASVGFLAILPFVATLLGIYLISVLTDKTGK
HHHHHHHHCCCCCEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RRLWVMVSLFCFAAALLASVVLRHNVVAAYIALVVCGFFLKAATSPFWSMPGRIASAEVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHC
GGARGVINGLGNLGGFCGPYLVGVMIYLYGQNVAVCALAVSLIIAGIIAWRLPRECDLTS
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SEPAHDPLLDKAKRA
CCCCCCHHHHHHCCC
>Mature Secondary Structure
MDNKIPNTRWLRVIAPILIACIISFMDRVNISFALPGGMESDLGITSQMAGLASGIFFIG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
YLFLQVPGGRIAVNGSGKRFIAWSLCAWAVVSVATGFVTNHYQLLILRFVLGISEGGMLP
HHHHCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VVLTMISNWFPEKELGRANAFVMMFAPLGGMLTAPISGAIINQLDWRWLFILEGLLSLVV
HHHHHHHCCCCCHHHCCCCEEEEEECCCCCHHHCCCCHHHHHHCCHHHHHHHHHHHHHHH
LAVWWLLISDRPQEARWLPAREREYLITELTRERQARSKMQPVSKAPLRDVFRNKGLMKL
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHH
VLLNFFYQTGDYGYTLWLPTILKNLTGGNMASVGFLAILPFVATLLGIYLISVLTDKTGK
HHHHHHHHCCCCCEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RRLWVMVSLFCFAAALLASVVLRHNVVAAYIALVVCGFFLKAATSPFWSMPGRIASAEVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHC
GGARGVINGLGNLGGFCGPYLVGVMIYLYGQNVAVCALAVSLIIAGIIAWRLPRECDLTS
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SEPAHDPLLDKAKRA
CCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]