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The map label for this gene is yfcG [H]

Identifier: 157369772

GI number: 157369772

Start: 1668110

End: 1668817

Strand: Reverse

Name: yfcG [H]

Synonym: Spro_1529

Alternate gene names: 157369772

Gene position: 1668817-1668110 (Counterclockwise)

Preceding gene: 157369775

Following gene: 157369771

Centisome position: 30.63

GC content: 55.65

Gene sequence:

>708_bases
ATGCTCGACCAAACCCAATTTCCGATCGTCAAACGCTGGCCCGCTCAGCACCCGGAAAGACTACAACTTTACTCATTGCC
AACGCCCAACGGTGTCAAGGTCTCCATCATGCTGGAAGAAATAGGTCTGGCTTATGAACCGCACCTGATCGATATCGGCA
ACAACGAAACCTGGACGCCGGAATTTCTGTCACTGAACCCGAACGGCAAGATCCCCTCGATCATCGATCCCAACGGCCCG
GACGGTAAGCCGCTGGCGCTGTTTGAATCCGGCGCTATCCTGCTATACCTGGCGGAAAAAAGCGGCAAGTTCCTGCCGCA
GGATCCCGCTCTGCGCTACGAAACCATCCAGTGGGTATTTTTCCAGATGGCGGCGGTGGGCCCGATGTTCGGTCAAGTCG
GCTTCTTCCACAAATTCGCCGGTCGCGAATATGAGGATAAACGTCCGCTGGAACGCTATAAAAATGAATCCAAACGCCTG
CTCGGCGTGCTGGAAACCCGGCTTGAAGGCCGTGACTGGATCATGGGGCAGGATTACAGCATCGCCGATATTTCATTGCT
GGGCTGGGTACGTAACCTGATCGGCTTTTATGAAGCCCGTGAGTTGGTCGAGTTCGATAGTTTCCCGCGGGTAGGACAAT
GGCTGGAGCGCGGTCTGGCCCGTCCAGCAGTACAACGCGGCCTGAATATTCCCGCCCGCAGCGAATAA

Upstream 100 bases:

>100_bases
GAAAGCGCTGAAAGCACATTTTGACCTCACGGTTTAACCTCACAACAGGTTAGTTTTGGTGCAATACTCAATAGGCAAAC
CGTCAACCCGAGGACTCGTC

Downstream 100 bases:

>100_bases
TGGATAGCCTGGGATAGCCGCCCGGCTATCCTTTTATCCCCAATTACCGTCATAAAAGTGTCACACCTCTGCACTACTCT
CCCTGCGTAACAAACTGATG

Product: glutathione S-transferase domain-containing protein

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MLDQTQFPIVKRWPAQHPERLQLYSLPTPNGVKVSIMLEEIGLAYEPHLIDIGNNETWTPEFLSLNPNGKIPSIIDPNGP
DGKPLALFESGAILLYLAEKSGKFLPQDPALRYETIQWVFFQMAAVGPMFGQVGFFHKFAGREYEDKRPLERYKNESKRL
LGVLETRLEGRDWIMGQDYSIADISLLGWVRNLIGFYEARELVEFDSFPRVGQWLERGLARPAVQRGLNIPARSE

Sequences:

>Translated_235_residues
MLDQTQFPIVKRWPAQHPERLQLYSLPTPNGVKVSIMLEEIGLAYEPHLIDIGNNETWTPEFLSLNPNGKIPSIIDPNGP
DGKPLALFESGAILLYLAEKSGKFLPQDPALRYETIQWVFFQMAAVGPMFGQVGFFHKFAGREYEDKRPLERYKNESKRL
LGVLETRLEGRDWIMGQDYSIADISLLGWVRNLIGFYEARELVEFDSFPRVGQWLERGLARPAVQRGLNIPARSE
>Mature_235_residues
MLDQTQFPIVKRWPAQHPERLQLYSLPTPNGVKVSIMLEEIGLAYEPHLIDIGNNETWTPEFLSLNPNGKIPSIIDPNGP
DGKPLALFESGAILLYLAEKSGKFLPQDPALRYETIQWVFFQMAAVGPMFGQVGFFHKFAGREYEDKRPLERYKNESKRL
LGVLETRLEGRDWIMGQDYSIADISLLGWVRNLIGFYEARELVEFDSFPRVGQWLERGLARPAVQRGLNIPARSE

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=209, Percent_Identity=43.5406698564593, Blast_Score=164, Evalue=4e-42,
Organism=Escherichia coli, GI87082195, Length=221, Percent_Identity=42.0814479638009, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI87081789, Length=173, Percent_Identity=25.4335260115607, Blast_Score=60, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6324100, Length=259, Percent_Identity=30.8880308880309, Blast_Score=105, Evalue=4e-24,
Organism=Drosophila melanogaster, GI17933730, Length=204, Percent_Identity=29.4117647058824, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17864592, Length=202, Percent_Identity=29.7029702970297, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28571670, Length=182, Percent_Identity=30.2197802197802, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17864594, Length=200, Percent_Identity=31.5, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19922532, Length=203, Percent_Identity=31.0344827586207, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17864598, Length=204, Percent_Identity=27.9411764705882, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45549270, Length=202, Percent_Identity=28.2178217821782, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI85725204, Length=204, Percent_Identity=29.9019607843137, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17737923, Length=204, Percent_Identity=29.9019607843137, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24646249, Length=207, Percent_Identity=28.9855072463768, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24654983, Length=211, Percent_Identity=28.9099526066351, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 26874; Mature: 26874

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDQTQFPIVKRWPAQHPERLQLYSLPTPNGVKVSIMLEEIGLAYEPHLIDIGNNETWTP
CCCCCCCCHHHCCCCCCCCCEEEEECCCCCCEEEEEEEHHCCCEECCEEEECCCCCCCCC
EFLSLNPNGKIPSIIDPNGPDGKPLALFESGAILLYLAEKSGKFLPQDPALRYETIQWVF
CEEEECCCCCCCCCCCCCCCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCHHHHHHHHH
FQMAAVGPMFGQVGFFHKFAGREYEDKRPLERYKNESKRLLGVLETRLEGRDWIMGQDYS
HHHHHHCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCC
IADISLLGWVRNLIGFYEARELVEFDSFPRVGQWLERGLARPAVQRGLNIPARSE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHCCCCCCCCC
>Mature Secondary Structure
MLDQTQFPIVKRWPAQHPERLQLYSLPTPNGVKVSIMLEEIGLAYEPHLIDIGNNETWTP
CCCCCCCCHHHCCCCCCCCCEEEEECCCCCCEEEEEEEHHCCCEECCEEEECCCCCCCCC
EFLSLNPNGKIPSIIDPNGPDGKPLALFESGAILLYLAEKSGKFLPQDPALRYETIQWVF
CEEEECCCCCCCCCCCCCCCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCHHHHHHHHH
FQMAAVGPMFGQVGFFHKFAGREYEDKRPLERYKNESKRLLGVLETRLEGRDWIMGQDYS
HHHHHHCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCC
IADISLLGWVRNLIGFYEARELVEFDSFPRVGQWLERGLARPAVQRGLNIPARSE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]