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The map label for this gene is yicO [C]

Identifier: 157369358

GI number: 157369358

Start: 1228571

End: 1229914

Strand: Reverse

Name: yicO [C]

Synonym: Spro_1115

Alternate gene names: 157369358

Gene position: 1229914-1228571 (Counterclockwise)

Preceding gene: 157369359

Following gene: 157369357

Centisome position: 22.57

GC content: 57.59

Gene sequence:

>1344_bases
ATGGCTGAAAATTCAGTACCTACTCCAACACCAGGGGGCTGGCTGCAACGGCGTTTTCAACTGCATGCGCGGCAAAGTAA
TGTCAAAACCGAATGTCTGGCCGGTATCACCGGTTTTCTGGCGGCCGCTTATCTGTTGGTGGTGATCCCAGGGTTGTTAG
CCGTCGGCGGCATGGATAAGGGGGCTGCCACTACCGGCACCATTCTGGTGTTTGTGCTGGGTAGCTTGCTGATGGCGTTA
TACGGCAACCTGCCGTTTATCGTCGGACCGGGCATCGGCGGCTCGGTGTTGGTCGGCGTAACTCTTGCAGGCAGTGAAGG
CATCGGTTGGCAAATTGGCTTGGGTATCGCCTGCTGGTCCGGTATTTTGTTTTTCGCCCTGACGCGGCTCGGGCTACGTG
AGGTGGTCACCCGTTCGGTACCGCAATCGATCAAGCTGGGGCTAACGGCCTCTATCGGGCTGTTCGTGGCAATACTGGGG
TTCCGCAATGCCGGGCTGGTGCTGGCCAACGCAAAGTCCAATGCGTTGATGCTGGGTGATTTCACCGCGCCCGGTGCATT
GATCGCCCTATGCGGCCTGTTCCTGGCAATCGCCCTGCAGGCCCGACGTATTCCCGGTGCTATTTTGTGGGCCATCCTGT
TCGCTACTCTGGTCGGCATCCCGTTCGGCGTCACCCATCTGCCAACCAGCCTCGTGGCGATGCCGCATTCATTGGCCCCG
GTGCTTGGCCATGTTGACCTTATCGGTGCATTGAATATCGCCTTCCTGCCCTATTTGTTCGTCTTTTTCGCCTCGGAGTT
TTTCTCCACCATGGGCACCACGCTGGCCGTAGGCGGTGAAGCCGGCCTGCTGGACGAACACGGCAATATGCCGCACATCA
ACCGGCCCTTTATGGTGGACTCTATCGCCGCCGCGCTTGGCCCTATAGTCGGTATTCCTGCCGCCACCGCCCTGATTGAA
TCCTCTGCGGCGGCAGAAGCCGGTGGAAAAACCGGGCTAACCGCCTTGGCCGCTGCGGTGATGTTTTTGCTGATGCTGCT
GTTCACACCGATTGCGCTGATGATCCCGAAAGAAGCCACCGCCCCGGCGCTGATTTTGATCGGCCTGAATATGTTCAGCG
GACTACGCAAAGTTGATTTGGCCAACTTCACCGATGGCCTGCCGGTACTGATGATGGTAATGATCACCCTGATCGCCAAC
AGCTTTGGTACCGGTATCGCTGGTGGATTGCTGTTTTATATCATTATCAAGGTGATTGCCGGTCAATGGCGCGAAGTACC
CGCCGGGTTGTATCTGTTGGCGATCCCGCTGGCGTACTATTTTGCCACGCTGGTTAGGCACTGA

Upstream 100 bases:

>100_bases
TGGGAAACCCCGGCCTAAAAATAATCATAATAACAATATGTACCCTATGGATTTCAAGTTGCGGCTTAAAATACGACGGG
TAACGACGGAGAGAATTTAA

Downstream 100 bases:

>100_bases
TCTAAAAGTGGTGCACTGATATTCTGTCAGCGCACCACTTTAATAACTCGAGTACAGAAATATATTCTCTGTCGCCCTGT
AAAATAGACCACACAGGGAG

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MAENSVPTPTPGGWLQRRFQLHARQSNVKTECLAGITGFLAAAYLLVVIPGLLAVGGMDKGAATTGTILVFVLGSLLMAL
YGNLPFIVGPGIGGSVLVGVTLAGSEGIGWQIGLGIACWSGILFFALTRLGLREVVTRSVPQSIKLGLTASIGLFVAILG
FRNAGLVLANAKSNALMLGDFTAPGALIALCGLFLAIALQARRIPGAILWAILFATLVGIPFGVTHLPTSLVAMPHSLAP
VLGHVDLIGALNIAFLPYLFVFFASEFFSTMGTTLAVGGEAGLLDEHGNMPHINRPFMVDSIAAALGPIVGIPAATALIE
SSAAAEAGGKTGLTALAAAVMFLLMLLFTPIALMIPKEATAPALILIGLNMFSGLRKVDLANFTDGLPVLMMVMITLIAN
SFGTGIAGGLLFYIIIKVIAGQWREVPAGLYLLAIPLAYYFATLVRH

Sequences:

>Translated_447_residues
MAENSVPTPTPGGWLQRRFQLHARQSNVKTECLAGITGFLAAAYLLVVIPGLLAVGGMDKGAATTGTILVFVLGSLLMAL
YGNLPFIVGPGIGGSVLVGVTLAGSEGIGWQIGLGIACWSGILFFALTRLGLREVVTRSVPQSIKLGLTASIGLFVAILG
FRNAGLVLANAKSNALMLGDFTAPGALIALCGLFLAIALQARRIPGAILWAILFATLVGIPFGVTHLPTSLVAMPHSLAP
VLGHVDLIGALNIAFLPYLFVFFASEFFSTMGTTLAVGGEAGLLDEHGNMPHINRPFMVDSIAAALGPIVGIPAATALIE
SSAAAEAGGKTGLTALAAAVMFLLMLLFTPIALMIPKEATAPALILIGLNMFSGLRKVDLANFTDGLPVLMMVMITLIAN
SFGTGIAGGLLFYIIIKVIAGQWREVPAGLYLLAIPLAYYFATLVRH
>Mature_446_residues
AENSVPTPTPGGWLQRRFQLHARQSNVKTECLAGITGFLAAAYLLVVIPGLLAVGGMDKGAATTGTILVFVLGSLLMALY
GNLPFIVGPGIGGSVLVGVTLAGSEGIGWQIGLGIACWSGILFFALTRLGLREVVTRSVPQSIKLGLTASIGLFVAILGF
RNAGLVLANAKSNALMLGDFTAPGALIALCGLFLAIALQARRIPGAILWAILFATLVGIPFGVTHLPTSLVAMPHSLAPV
LGHVDLIGALNIAFLPYLFVFFASEFFSTMGTTLAVGGEAGLLDEHGNMPHINRPFMVDSIAAALGPIVGIPAATALIES
SAAAEAGGKTGLTALAAAVMFLLMLLFTPIALMIPKEATAPALILIGLNMFSGLRKVDLANFTDGLPVLMMVMITLIANS
FGTGIAGGLLFYIIIKVIAGQWREVPAGLYLLAIPLAYYFATLVRH

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=441, Percent_Identity=34.4671201814059, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI1790150, Length=435, Percent_Identity=33.3333333333333, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1790499, Length=443, Percent_Identity=33.4085778781038, Blast_Score=234, Evalue=8e-63,
Organism=Escherichia coli, GI48994909, Length=439, Percent_Identity=33.0296127562642, Blast_Score=211, Evalue=7e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46342; Mature: 46211

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENSVPTPTPGGWLQRRFQLHARQSNVKTECLAGITGFLAAAYLLVVIPGLLAVGGMDK
CCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAATTGTILVFVLGSLLMALYGNLPFIVGPGIGGSVLVGVTLAGSEGIGWQIGLGIACWS
CCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEEEEECCCCCCEEHHHHHHHHH
GILFFALTRLGLREVVTRSVPQSIKLGLTASIGLFVAILGFRNAGLVLANAKSNALMLGD
HHHHHHHHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEC
FTAPGALIALCGLFLAIALQARRIPGAILWAILFATLVGIPFGVTHLPTSLVAMPHSLAP
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHH
VLGHVDLIGALNIAFLPYLFVFFASEFFSTMGTTLAVGGEAGLLDEHGNMPHINRPFMVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCHHHH
SIAAALGPIVGIPAATALIESSAAAEAGGKTGLTALAAAVMFLLMLLFTPIALMIPKEAT
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
APALILIGLNMFSGLRKVDLANFTDGLPVLMMVMITLIANSFGTGIAGGLLFYIIIKVIA
CCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GQWREVPAGLYLLAIPLAYYFATLVRH
CCHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AENSVPTPTPGGWLQRRFQLHARQSNVKTECLAGITGFLAAAYLLVVIPGLLAVGGMDK
CCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAATTGTILVFVLGSLLMALYGNLPFIVGPGIGGSVLVGVTLAGSEGIGWQIGLGIACWS
CCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEEEEECCCCCCEEHHHHHHHHH
GILFFALTRLGLREVVTRSVPQSIKLGLTASIGLFVAILGFRNAGLVLANAKSNALMLGD
HHHHHHHHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEC
FTAPGALIALCGLFLAIALQARRIPGAILWAILFATLVGIPFGVTHLPTSLVAMPHSLAP
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHH
VLGHVDLIGALNIAFLPYLFVFFASEFFSTMGTTLAVGGEAGLLDEHGNMPHINRPFMVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCHHHH
SIAAALGPIVGIPAATALIESSAAAEAGGKTGLTALAAAVMFLLMLLFTPIALMIPKEAT
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
APALILIGLNMFSGLRKVDLANFTDGLPVLMMVMITLIANSFGTGIAGGLLFYIIIKVIA
CCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GQWREVPAGLYLLAIPLAYYFATLVRH
CCHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]