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The map label for this gene is ade

Identifier: 157369359

GI number: 157369359

Start: 1229997

End: 1231784

Strand: Reverse

Name: ade

Synonym: Spro_1116

Alternate gene names: 157369359

Gene position: 1231784-1229997 (Counterclockwise)

Preceding gene: 157369361

Following gene: 157369358

Centisome position: 22.61

GC content: 60.68

Gene sequence:

>1788_bases
ATGACCACTCATTGCATCAGCACGGGCGAACGCCAGCGTGCGGTGAAGGCCGCATTGGGCCAACTTCCCTTTGATTTGCT
GCTGACCAACGCCGCGTTAATTGACATGGCAACCGGCGAAGTCCGTAACGTCGACGTCGGCATCGTCGGCGCACTGATCG
CCAGCGTCCATCCCTGCGGCACCCTGACCGAAGCCTTGCAGACGCAGGACTTGGCCGGTGCTTATCTGAGCCCAGGACTG
ATCGACACCCACGTGCATGTTGAAAGCTCACACCTGCCGCCGGAACGTTATGCCGAGATCGTCGTCGCCCAAGGCACCAC
CACCATTTTCTGGGATCCGCACGAGTTGGCCAACGTGCTCGGCGTTGCCGGTGTGCGTTATGCGGTAGACGCCAGCCGCG
GCCTGCCACTCAGAGTGATCTGTGCAGCCCCTTCAAGCGTCCCCTCCACTCCGGGGCTGGAAATGTCCGGTGCCGATTTT
GCCGGCCAGGAAATGGAAACCATGCTGGCGTGGCCAGAAGTCGGCGGCGTCGCCGAGGTCATGGACATGCACGGCGTGTT
GAATGGCAGCGAGCGCATGCTGGAAATTCTCAATGCCGGGCTTAATAGCGGCAAATTGATCGAAGGCCATGCGCGCGGGC
TGAGCGGCGCCGACCTGCAGGCTTATCTGGCGGCTGGAGTCACCTCCGACCATGAGCTGACCTCCGGAGCCGATGCGCTG
GAGAAATTACGCGCCGGTCTGACGCTGGAAATCAGAGGTTCCCACCCTTATCTGCTGCCGGAGATTGTCGCGGCGCTGAA
AACGCTGCCGCACCTGTCCTCACAAATCACCGTCTGCACCGATGATGTCCCGCCGGATATGCTGCTGGAAAAAGGCGGCA
TAGTAGCGTTACTCAATATGTTGATCGAACAAGGCCTGCCGGCGACCGACGTGCTGCGGATGGCCACGCTCAATGCCGCC
ATTCGTTTGCAGCGCAACGATCTCGGGCTGATTGCCGCAGGCCGCGTTGCCGATCTGGTGGTGTTTGATTCGCTGACTCA
GCTTAGAGCGCAACAAGTCTACGTCGCAGGTAAATTGACGGCACAGCAAGGCAAGATGCAAAAGCCGCTCAACGCCAACC
CTAACGTGGCGGCACCGCGTGACACCCTGCGGCTGCAACCTTTGGCTGCCGGGGACTTTGTGTTGAAGGTTCCGGCGATC
CGTCACGGCAAAGCCACTCTACGCCACATAAAGGGCGCGCGTTTTACCCAGTGGAACGAAACCACGGTCGAAGTGCGTAA
CGGTGAAGTGCAGATCCCGCAAGGCTTTAGCCTGATCTGGGTGCAGCACCGCCATGGCCGCCATCAGGCCACACCGCAAC
TGGCATTGCTGGAGGGCTGGGGTGAGTTGCGGGGTGCCATTGCCACCAGCTACTCACATGACTCACATAATCTGGTTGTG
CTGGGGCGTGATGCCGCCGACATGGCGCTGGCCGCCAACGCCCTGATTGCCAGTGGCGGCGGCATGGCCCTGAGTCAAAA
CGGGGAAATTCTGGCGCAAGTGGCAATGCCGATTGCCGGTATGCTCTCTGACTTGCCCGCCGCAGAGCTGGCACAACAGT
TCAAAAACCTGCGCGATTTGAGCGCACGAATCGCCGACTGGGAACCGCCTTACCGGGTTTTCAAGGCGATTGAAGGCACC
TGCCTGGCGTGTAACGCCGGGCCGCACCTGACCGATCTCGGCCTGACCGATGGCTCAACACGTCAGATTGTCGATCCGCT
GATCGCCTGCTGGGAAACCCCGGCCTAA

Upstream 100 bases:

>100_bases
CAGCATAAACGTTTCTTATCAGGCGATAAATTAAATCATCTGTGCAAAGCCAGTCCGCCGCCCTAGAGTAACAACCCTGT
CATCATGCCGGGTAATTACC

Downstream 100 bases:

>100_bases
AAATAATCATAATAACAATATGTACCCTATGGATTTCAAGTTGCGGCTTAAAATACGACGGGTAACGACGGAGAGAATTT
AAATGGCTGAAAATTCAGTA

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase

Number of amino acids: Translated: 595; Mature: 594

Protein sequence:

>595_residues
MTTHCISTGERQRAVKAALGQLPFDLLLTNAALIDMATGEVRNVDVGIVGALIASVHPCGTLTEALQTQDLAGAYLSPGL
IDTHVHVESSHLPPERYAEIVVAQGTTTIFWDPHELANVLGVAGVRYAVDASRGLPLRVICAAPSSVPSTPGLEMSGADF
AGQEMETMLAWPEVGGVAEVMDMHGVLNGSERMLEILNAGLNSGKLIEGHARGLSGADLQAYLAAGVTSDHELTSGADAL
EKLRAGLTLEIRGSHPYLLPEIVAALKTLPHLSSQITVCTDDVPPDMLLEKGGIVALLNMLIEQGLPATDVLRMATLNAA
IRLQRNDLGLIAAGRVADLVVFDSLTQLRAQQVYVAGKLTAQQGKMQKPLNANPNVAAPRDTLRLQPLAAGDFVLKVPAI
RHGKATLRHIKGARFTQWNETTVEVRNGEVQIPQGFSLIWVQHRHGRHQATPQLALLEGWGELRGAIATSYSHDSHNLVV
LGRDAADMALAANALIASGGGMALSQNGEILAQVAMPIAGMLSDLPAAELAQQFKNLRDLSARIADWEPPYRVFKAIEGT
CLACNAGPHLTDLGLTDGSTRQIVDPLIACWETPA

Sequences:

>Translated_595_residues
MTTHCISTGERQRAVKAALGQLPFDLLLTNAALIDMATGEVRNVDVGIVGALIASVHPCGTLTEALQTQDLAGAYLSPGL
IDTHVHVESSHLPPERYAEIVVAQGTTTIFWDPHELANVLGVAGVRYAVDASRGLPLRVICAAPSSVPSTPGLEMSGADF
AGQEMETMLAWPEVGGVAEVMDMHGVLNGSERMLEILNAGLNSGKLIEGHARGLSGADLQAYLAAGVTSDHELTSGADAL
EKLRAGLTLEIRGSHPYLLPEIVAALKTLPHLSSQITVCTDDVPPDMLLEKGGIVALLNMLIEQGLPATDVLRMATLNAA
IRLQRNDLGLIAAGRVADLVVFDSLTQLRAQQVYVAGKLTAQQGKMQKPLNANPNVAAPRDTLRLQPLAAGDFVLKVPAI
RHGKATLRHIKGARFTQWNETTVEVRNGEVQIPQGFSLIWVQHRHGRHQATPQLALLEGWGELRGAIATSYSHDSHNLVV
LGRDAADMALAANALIASGGGMALSQNGEILAQVAMPIAGMLSDLPAAELAQQFKNLRDLSARIADWEPPYRVFKAIEGT
CLACNAGPHLTDLGLTDGSTRQIVDPLIACWETPA
>Mature_594_residues
TTHCISTGERQRAVKAALGQLPFDLLLTNAALIDMATGEVRNVDVGIVGALIASVHPCGTLTEALQTQDLAGAYLSPGLI
DTHVHVESSHLPPERYAEIVVAQGTTTIFWDPHELANVLGVAGVRYAVDASRGLPLRVICAAPSSVPSTPGLEMSGADFA
GQEMETMLAWPEVGGVAEVMDMHGVLNGSERMLEILNAGLNSGKLIEGHARGLSGADLQAYLAAGVTSDHELTSGADALE
KLRAGLTLEIRGSHPYLLPEIVAALKTLPHLSSQITVCTDDVPPDMLLEKGGIVALLNMLIEQGLPATDVLRMATLNAAI
RLQRNDLGLIAAGRVADLVVFDSLTQLRAQQVYVAGKLTAQQGKMQKPLNANPNVAAPRDTLRLQPLAAGDFVLKVPAIR
HGKATLRHIKGARFTQWNETTVEVRNGEVQIPQGFSLIWVQHRHGRHQATPQLALLEGWGELRGAIATSYSHDSHNLVVL
GRDAADMALAANALIASGGGMALSQNGEILAQVAMPIAGMLSDLPAAELAQQFKNLRDLSARIADWEPPYRVFKAIEGTC
LACNAGPHLTDLGLTDGSTRQIVDPLIACWETPA

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=543, Percent_Identity=34.4383057090239, Blast_Score=258, Evalue=5e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC_SERP5 (A8GAT0)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001477348.1
- ProteinModelPortal:   A8GAT0
- STRING:   A8GAT0
- GeneID:   5606324
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_1116
- eggNOG:   COG1001
- HOGENOM:   HBG725357
- OMA:   IELRGSH
- ProtClustDB:   CLSK881699
- BioCyc:   SPRO399741:SPRO_1116-MONOMER
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 63139; Mature: 63008

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTHCISTGERQRAVKAALGQLPFDLLLTNAALIDMATGEVRNVDVGIVGALIASVHPCG
CCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHEEEECCCCCEECCHHHHHHHHHHCCCCH
TLTEALQTQDLAGAYLSPGLIDTHVHVESSHLPPERYAEIVVAQGTTTIFWDPHELANVL
HHHHHHHHHHHCCHHCCCCEEEEEEEEECCCCCHHHHHEEEEECCCEEEEECHHHHHHHH
GVAGVRYAVDASRGLPLRVICAAPSSVPSTPGLEMSGADFAGQEMETMLAWPEVGGVAEV
HHCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHH
MDMHGVLNGSERMLEILNAGLNSGKLIEGHARGLSGADLQAYLAAGVTSDHELTSGADAL
HHHHHCCCCHHHHHHHHHCCCCCCCEEEHHCCCCCCCCHHHHHHHCCCCCCCCCCHHHHH
EKLRAGLTLEIRGSHPYLLPEIVAALKTLPHLSSQITVCTDDVPPDMLLEKGGIVALLNM
HHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCHHHHHHH
LIEQGLPATDVLRMATLNAAIRLQRNDLGLIAAGRVADLVVFDSLTQLRAQQVYVAGKLT
HHHCCCCHHHHHHHHHHCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHEEEEEEEE
AQQGKMQKPLNANPNVAAPRDTLRLQPLAAGDFVLKVPAIRHGKATLRHIKGARFTQWNE
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCHHHHHHHCCCCEECCCC
TTVEVRNGEVQIPQGFSLIWVQHRHGRHQATPQLALLEGWGELRGAIATSYSHDSHNLVV
EEEEEECCEEECCCCCEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCEEE
LGRDAADMALAANALIASGGGMALSQNGEILAQVAMPIAGMLSDLPAAELAQQFKNLRDL
EECCHHHHHHHHHHHEECCCCEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
SARIADWEPPYRVFKAIEGTCLACNAGPHLTDLGLTDGSTRQIVDPLIACWETPA
HHHHCCCCCHHHHHHHCCCCEEEECCCCCEEECCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTHCISTGERQRAVKAALGQLPFDLLLTNAALIDMATGEVRNVDVGIVGALIASVHPCG
CCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHEEEECCCCCEECCHHHHHHHHHHCCCCH
TLTEALQTQDLAGAYLSPGLIDTHVHVESSHLPPERYAEIVVAQGTTTIFWDPHELANVL
HHHHHHHHHHHCCHHCCCCEEEEEEEEECCCCCHHHHHEEEEECCCEEEEECHHHHHHHH
GVAGVRYAVDASRGLPLRVICAAPSSVPSTPGLEMSGADFAGQEMETMLAWPEVGGVAEV
HHCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHH
MDMHGVLNGSERMLEILNAGLNSGKLIEGHARGLSGADLQAYLAAGVTSDHELTSGADAL
HHHHHCCCCHHHHHHHHHCCCCCCCEEEHHCCCCCCCCHHHHHHHCCCCCCCCCCHHHHH
EKLRAGLTLEIRGSHPYLLPEIVAALKTLPHLSSQITVCTDDVPPDMLLEKGGIVALLNM
HHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCHHHHHHH
LIEQGLPATDVLRMATLNAAIRLQRNDLGLIAAGRVADLVVFDSLTQLRAQQVYVAGKLT
HHHCCCCHHHHHHHHHHCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHEEEEEEEE
AQQGKMQKPLNANPNVAAPRDTLRLQPLAAGDFVLKVPAIRHGKATLRHIKGARFTQWNE
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCHHHHHHHCCCCEECCCC
TTVEVRNGEVQIPQGFSLIWVQHRHGRHQATPQLALLEGWGELRGAIATSYSHDSHNLVV
EEEEEECCEEECCCCCEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCEEE
LGRDAADMALAANALIASGGGMALSQNGEILAQVAMPIAGMLSDLPAAELAQQFKNLRDL
EECCHHHHHHHHHHHEECCCCEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
SARIADWEPPYRVFKAIEGTCLACNAGPHLTDLGLTDGSTRQIVDPLIACWETPA
HHHHCCCCCHHHHHHHCCCCEEEECCCCCEEECCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA