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The map label for this gene is queC

Identifier: 157369345

GI number: 157369345

Start: 1212871

End: 1213569

Strand: Reverse

Name: queC

Synonym: Spro_1102

Alternate gene names: 157369345

Gene position: 1213569-1212871 (Counterclockwise)

Preceding gene: 157369346

Following gene: 157369335

Centisome position: 22.27

GC content: 56.65

Gene sequence:

>699_bases
ATGAAGCGCGCGGTTGTCGTTTTCAGCGGTGGACAAGATTCCACGACCTGCTTGATTCAGGCATTGAAACAGTATGATGA
AGTTCACTGCGTCACCTTTGACTACGGCCAGCGTCATCGTGCCGAAATTGAGGTGGCTCAGGAACTGTCAGTGGCCCTGG
GAGCCAAGGCGCATAAGCTGTTGGACGTAGGCCTGCTCAATGAGCTGGCGATCAGCAGCCTGACCCGTGACAACATTCCG
GTTCCCGCCTACGACAGCACGCAGAGCAATGGGTTACCGAGCACCTTTGTGCCGGGCCGCAACATTCTGTTCCTGACGCT
GGCGGCGATTTATGCCTATCAGGTCGAAGCTGAAGCGGTGATCACCGGCGTGTGTGAAACCGACTTCTCCGGCTACCCAG
ACTGTCGCGACGAGTTTGTCAAAGCGCTGAACCAGGCAATAGTTCTGGGCATCGCCCGCGATATCCGCTTTGAAACGCCG
TTGATGTGGCTGAACAAGGCAGAAACCTGGGCACTGGCAGATTACTACCATCAGCTGGAGCTGGTGCAGCAGGACACTCT
GACCTGCTACAACGGCATCAAAGGCAATGGCTGCGGTGAATGTGCGGCCTGTCATCTGCGCGCCAACGGCCTGCAGCAGT
ACCAAATCAACAAGGCCGAAGTGATGGCGAGCCTGAAGCAAAAGACCGGGCTGGTCTGA

Upstream 100 bases:

>100_bases
TATGCCACCATTTCTGCTACCATTGCTGCCGCAACGCATTTTTATCTTACCGCCCGAATGTGTATCGGGTAGGGTCTCAG
CAATAAATTGAGGTTATTTT

Downstream 100 bases:

>100_bases
TTGAATAACGGCGGCACAGGTTGCCGCTCGTTGCTTTACCTATCTTCAAGCGGCGTGAGCACCTGCAGGTGTTCGCGCAG
TTGCCCTTCGATCGGCAATG

Product: queuosine biosynthesis protein QueC

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MKRAVVVFSGGQDSTTCLIQALKQYDEVHCVTFDYGQRHRAEIEVAQELSVALGAKAHKLLDVGLLNELAISSLTRDNIP
VPAYDSTQSNGLPSTFVPGRNILFLTLAAIYAYQVEAEAVITGVCETDFSGYPDCRDEFVKALNQAIVLGIARDIRFETP
LMWLNKAETWALADYYHQLELVQQDTLTCYNGIKGNGCGECAACHLRANGLQQYQINKAEVMASLKQKTGLV

Sequences:

>Translated_232_residues
MKRAVVVFSGGQDSTTCLIQALKQYDEVHCVTFDYGQRHRAEIEVAQELSVALGAKAHKLLDVGLLNELAISSLTRDNIP
VPAYDSTQSNGLPSTFVPGRNILFLTLAAIYAYQVEAEAVITGVCETDFSGYPDCRDEFVKALNQAIVLGIARDIRFETP
LMWLNKAETWALADYYHQLELVQQDTLTCYNGIKGNGCGECAACHLRANGLQQYQINKAEVMASLKQKTGLV
>Mature_232_residues
MKRAVVVFSGGQDSTTCLIQALKQYDEVHCVTFDYGQRHRAEIEVAQELSVALGAKAHKLLDVGLLNELAISSLTRDNIP
VPAYDSTQSNGLPSTFVPGRNILFLTLAAIYAYQVEAEAVITGVCETDFSGYPDCRDEFVKALNQAIVLGIARDIRFETP
LMWLNKAETWALADYYHQLELVQQDTLTCYNGIKGNGCGECAACHLRANGLQQYQINKAEVMASLKQKTGLV

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=231, Percent_Identity=79.2207792207792, Blast_Score=396, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_SERP5 (A8GAR6)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001477334.1
- ProteinModelPortal:   A8GAR6
- SMR:   A8GAR6
- STRING:   A8GAR6
- GeneID:   5604737
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_1102
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- ProtClustDB:   PRK11106
- BioCyc:   SPRO399741:SPRO_1102-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25539; Mature: 25539

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRAVVVFSGGQDSTTCLIQALKQYDEVHCVTFDYGQRHRAEIEVAQELSVALGAKAHKL
CCEEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHH
LDVGLLNELAISSLTRDNIPVPAYDSTQSNGLPSTFVPGRNILFLTLAAIYAYQVEAEAV
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEHHHH
ITGVCETDFSGYPDCRDEFVKALNQAIVLGIARDIRFETPLMWLNKAETWALADYYHQLE
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHH
LVQQDTLTCYNGIKGNGCGECAACHLRANGLQQYQINKAEVMASLKQKTGLV
HHHHHHHHHHCCCCCCCCCCHHEEEHHHCCCHHHCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRAVVVFSGGQDSTTCLIQALKQYDEVHCVTFDYGQRHRAEIEVAQELSVALGAKAHKL
CCEEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHH
LDVGLLNELAISSLTRDNIPVPAYDSTQSNGLPSTFVPGRNILFLTLAAIYAYQVEAEAV
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEHHHH
ITGVCETDFSGYPDCRDEFVKALNQAIVLGIARDIRFETPLMWLNKAETWALADYYHQLE
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHH
LVQQDTLTCYNGIKGNGCGECAACHLRANGLQQYQINKAEVMASLKQKTGLV
HHHHHHHHHHCCCCCCCCCCHHEEEHHHCCCHHHCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA