Click here to switch to the map view.

The map label for this gene is hupB [H]

Identifier: 157369341

GI number: 157369341

Start: 1209366

End: 1209671

Strand: Direct

Name: hupB [H]

Synonym: Spro_1098

Alternate gene names: 157369341

Gene position: 1209366-1209671 (Clockwise)

Preceding gene: 157369340

Following gene: 157369342

Centisome position: 22.19

GC content: 52.29

Gene sequence:

>306_bases
GTGCGACGATTGAATTCTAGAGGGGATGATAGAGTGAATAAGTCACAACTGATCGACAAAATTGCCGCAGGTGCTGATAT
TTCCAAAGCGGCAGCTGGACGTGCTTTAGATGCAGTGATTGCATCTGTTACTGACTCCTTGAAGGAAGGGGATGACGTGG
CCCTGGTGGGTTTCGGTTCCTTCACCGTGCGTGAACGTTCGGCCCGTACCGGTCGTAACCCGCAAACCGGTAAAGAGATC
AAAATCGCGGCAGCCAAAGTTCCGGCCTTCCGTGCAGGGAAAGCGCTGAAAGACGCAGTAAACTGA

Upstream 100 bases:

>100_bases
GACAGCTGTCGGCCCGCGTTTTGTCACGCTTACGGTGGCTTGCCAAGGCACGATGGGATTGATATAACAGCTGCGCTGTC
GCAACCGTAGGGATTTTTCG

Downstream 100 bases:

>100_bases
TTGTTTGCGTCTAACCGTTTAGCGTTACAGGGCTTTGTAATAAACAATCACCTGACGCAACGGTGCTGGTAAGGTAAGAT
ATAAGGCGCATCAGATTGAT

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: HU-1; NS1 [H]

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MRRLNSRGDDRVNKSQLIDKIAAGADISKAAAGRALDAVIASVTDSLKEGDDVALVGFGSFTVRERSARTGRNPQTGKEI
KIAAAKVPAFRAGKALKDAVN

Sequences:

>Translated_101_residues
MRRLNSRGDDRVNKSQLIDKIAAGADISKAAAGRALDAVIASVTDSLKEGDDVALVGFGSFTVRERSARTGRNPQTGKEI
KIAAAKVPAFRAGKALKDAVN
>Mature_101_residues
MRRLNSRGDDRVNKSQLIDKIAAGADISKAAAGRALDAVIASVTDSLKEGDDVALVGFGSFTVRERSARTGRNPQTGKEI
KIAAAKVPAFRAGKALKDAVN

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=90, Blast_Score=161, Evalue=8e-42,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=67.4157303370787, Blast_Score=121, Evalue=8e-30,
Organism=Escherichia coli, GI1787141, Length=91, Percent_Identity=34.0659340659341, Blast_Score=70, Evalue=4e-14,
Organism=Escherichia coli, GI1788005, Length=84, Percent_Identity=38.0952380952381, Blast_Score=63, Evalue=3e-12,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 10594; Mature: 10594

Theoretical pI: Translated: 11.03; Mature: 11.03

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLNSRGDDRVNKSQLIDKIAAGADISKAAAGRALDAVIASVTDSLKEGDDVALVGFGS
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
FTVRERSARTGRNPQTGKEIKIAAAKVPAFRAGKALKDAVN
CEECCCHHCCCCCCCCCCEEEEECCCCCCHHCCHHHHHHCC
>Mature Secondary Structure
MRRLNSRGDDRVNKSQLIDKIAAGADISKAAAGRALDAVIASVTDSLKEGDDVALVGFGS
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
FTVRERSARTGRNPQTGKEIKIAAAKVPAFRAGKALKDAVN
CEECCCHHCCCCCCCCCCEEEEECCCCCCHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550432 [H]