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The map label for this gene is ppiD [H]

Identifier: 157369342

GI number: 157369342

Start: 1209854

End: 1211737

Strand: Direct

Name: ppiD [H]

Synonym: Spro_1099

Alternate gene names: 157369342

Gene position: 1209854-1211737 (Clockwise)

Preceding gene: 157369341

Following gene: 157369343

Centisome position: 22.2

GC content: 55.68

Gene sequence:

>1884_bases
ATGATGGACAATTTACGCGCGGCAGCTAATCACGTCGTGCTCAAAATCATCCTGGGCTTGATCATTTTGTCATTTCTTTT
GACAGGGGTGGTCAGCTATCAGGGGAGTGCCGGTGATTATGCAGCGAAGGTCAATGGCCAGGTGATCGAGCGTGCTCAGC
TGGAACAGGCTTTCCAAAGCGAACGCAGCCGCATGCAGCAACAGTTGGGTGACCAGTTCTCCGCACTGGCGGGCAACGAA
GGCTATATGCAGCAGATGCGCCATCAGGCACTGTCACAGCTGATCGACAACATGCTGCTGGACCAATATGCCAAGAAATT
AGGCCTGAGCGTCAGTGACGATCAGGTGAAAGAAGCTATCCGTAAAGCACCTTACTTCCAGACAAACGGCCAGTTCGATA
ACGCCAAATATCTCGATCTGATTAGCCGCATGGGTTACACCGCCGATAACTTTGCACAATCAATGCGTCAGCAGTTGGTT
AACCAGCAGGTGATCCAGGCCTTTGGCGGTTCGGGCTTTATTCTGCCTGCCGAAGCTCAGGACATGACGGCACTGGTGCT
GCAACAGCGCGATGTGCGCTTGGCTACGCTGGATCTGAAAGCGTTGCAGGCCAAGCAGACCGTGACCGACGACGAGCTGA
AAGACTACTACAGCCAGAACAAGAACAGCTTTATTGCGCCAGAACAGGTCAAAGTAAGCTACATCCCAATGGACGCCGCT
GCTATGCAAGACAAGGTGACGGTAGCCGACGCGGATATCAGCGCCTATTACGACCAGCACAAAAGCAGCTACGGCCAGCC
TGAACGCAAGAACTACAGCGTGATCCAGTTGAAAACCGAGGCGGAAGCCAATGCGGTACTGGATGAACTGAAGAAAGGCG
GCGATTTTGCCACCCTGGCGAAAGACAAATCCACTGACATCATTTCACGCCGTACCGGCGGTGAACTGGGCTGGCTGGAG
CCGGACACCACTGCAGACGAACTCAAGCAGGCTAACCTGACCGAAAAAGGCCAGCTTTCCGGCGTCGTGAAGTCTTCAGT
AGGCTATCTGGTGATCCGCCTCAACGACATCGCACCGGAAAAAGTGAAGCCGTTGAGCGAAGTGCGTGACGCTATCGCCA
AGCAGGTTAAGCAGGAGAAAGCGGTAGACGCTTATTACGCACTGCAACAGAAGGTGAGTGAAGCGGCTACCAGCGATAAC
GAGTCTCTGGCATCGGCCGAAGAGGCCGCCGGCGTGAAAGCGGCGCAGACCGACTGGTTTACCCGCGACAATATTCCGGC
AGCGCTGAACTTCAAACCGGTCATTCAGTCGATTTTCGACGGTTCCCTGATTGGTGAAGGCGGCTCTCCGGGCAGCAACT
CCGACGTGATCACCGTTGATGGCGACCGTGCCTTCGTGATCCGTGTGTCTGGCCACAAGCCAGAGGGCATTGAGCCGTTC
GACCAGGTGAAAGATCGCGTGGCAGAACTGGTCAAGCGCAACAAAGCTGAACAGGAAGCCAAACTGCAGGGCGAGAAGCT
GCTGGTTGAGCTGAAGCAGGGTAAGGGCGACGAGGCGATGAAAGCCGCCGGCCTGAGCTTTGGCAGCGTACAGAAGATGG
CGCGCGCGCCGGAAGACAGCCAACTGGTGCAGAGCGTGTTCGCGCTGCCGCATCCGCAAGAAGGCAAGCCGGTTTATGGC
ATGTCGCAGGACCGTCAGGACAACGTGGTACTGATTGCACTGGATGCCGTGAAGCCAGGCACCTTGCCGGCTGAAGAAAT
GAAAACCTTCGTCAGCAAGATGGAAGAAGGTGCGACTGGCGTGTCCTTTGACTCTCTGCTGGCCAGCCTGCGCAAAGAAG
CCAAGATCACCATGGGTGCCGCTGAACAGCAGCAACCTCAGTAA

Upstream 100 bases:

>100_bases
AAGGCGCATCAGATTGATGCGCTTTTTTTATTTTTGTCGCAGGGAACGCGCCTGCACAAGGGTGTTTTTAATCCACATCA
CAGCGGAGTGTTGTCACACT

Downstream 100 bases:

>100_bases
AGCGCCGCAGTTTTCTGCAACGCAATGTAATCCTCAAAGGCCGCTTTCGCGGCCTTTTCCATATCTGAAATCCGCCAATT
GCTGAAGTTTCTTCGCTGCG

Product: peptidyl-prolyl cis-trans isomerase D

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MMDNLRAAANHVVLKIILGLIILSFLLTGVVSYQGSAGDYAAKVNGQVIERAQLEQAFQSERSRMQQQLGDQFSALAGNE
GYMQQMRHQALSQLIDNMLLDQYAKKLGLSVSDDQVKEAIRKAPYFQTNGQFDNAKYLDLISRMGYTADNFAQSMRQQLV
NQQVIQAFGGSGFILPAEAQDMTALVLQQRDVRLATLDLKALQAKQTVTDDELKDYYSQNKNSFIAPEQVKVSYIPMDAA
AMQDKVTVADADISAYYDQHKSSYGQPERKNYSVIQLKTEAEANAVLDELKKGGDFATLAKDKSTDIISRRTGGELGWLE
PDTTADELKQANLTEKGQLSGVVKSSVGYLVIRLNDIAPEKVKPLSEVRDAIAKQVKQEKAVDAYYALQQKVSEAATSDN
ESLASAEEAAGVKAAQTDWFTRDNIPAALNFKPVIQSIFDGSLIGEGGSPGSNSDVITVDGDRAFVIRVSGHKPEGIEPF
DQVKDRVAELVKRNKAEQEAKLQGEKLLVELKQGKGDEAMKAAGLSFGSVQKMARAPEDSQLVQSVFALPHPQEGKPVYG
MSQDRQDNVVLIALDAVKPGTLPAEEMKTFVSKMEEGATGVSFDSLLASLRKEAKITMGAAEQQQPQ

Sequences:

>Translated_627_residues
MMDNLRAAANHVVLKIILGLIILSFLLTGVVSYQGSAGDYAAKVNGQVIERAQLEQAFQSERSRMQQQLGDQFSALAGNE
GYMQQMRHQALSQLIDNMLLDQYAKKLGLSVSDDQVKEAIRKAPYFQTNGQFDNAKYLDLISRMGYTADNFAQSMRQQLV
NQQVIQAFGGSGFILPAEAQDMTALVLQQRDVRLATLDLKALQAKQTVTDDELKDYYSQNKNSFIAPEQVKVSYIPMDAA
AMQDKVTVADADISAYYDQHKSSYGQPERKNYSVIQLKTEAEANAVLDELKKGGDFATLAKDKSTDIISRRTGGELGWLE
PDTTADELKQANLTEKGQLSGVVKSSVGYLVIRLNDIAPEKVKPLSEVRDAIAKQVKQEKAVDAYYALQQKVSEAATSDN
ESLASAEEAAGVKAAQTDWFTRDNIPAALNFKPVIQSIFDGSLIGEGGSPGSNSDVITVDGDRAFVIRVSGHKPEGIEPF
DQVKDRVAELVKRNKAEQEAKLQGEKLLVELKQGKGDEAMKAAGLSFGSVQKMARAPEDSQLVQSVFALPHPQEGKPVYG
MSQDRQDNVVLIALDAVKPGTLPAEEMKTFVSKMEEGATGVSFDSLLASLRKEAKITMGAAEQQQPQ
>Mature_627_residues
MMDNLRAAANHVVLKIILGLIILSFLLTGVVSYQGSAGDYAAKVNGQVIERAQLEQAFQSERSRMQQQLGDQFSALAGNE
GYMQQMRHQALSQLIDNMLLDQYAKKLGLSVSDDQVKEAIRKAPYFQTNGQFDNAKYLDLISRMGYTADNFAQSMRQQLV
NQQVIQAFGGSGFILPAEAQDMTALVLQQRDVRLATLDLKALQAKQTVTDDELKDYYSQNKNSFIAPEQVKVSYIPMDAA
AMQDKVTVADADISAYYDQHKSSYGQPERKNYSVIQLKTEAEANAVLDELKKGGDFATLAKDKSTDIISRRTGGELGWLE
PDTTADELKQANLTEKGQLSGVVKSSVGYLVIRLNDIAPEKVKPLSEVRDAIAKQVKQEKAVDAYYALQQKVSEAATSDN
ESLASAEEAAGVKAAQTDWFTRDNIPAALNFKPVIQSIFDGSLIGEGGSPGSNSDVITVDGDRAFVIRVSGHKPEGIEPF
DQVKDRVAELVKRNKAEQEAKLQGEKLLVELKQGKGDEAMKAAGLSFGSVQKMARAPEDSQLVQSVFALPHPQEGKPVYG
MSQDRQDNVVLIALDAVKPGTLPAEEMKTFVSKMEEGATGVSFDSLLASLRKEAKITMGAAEQQQPQ

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=626, Percent_Identity=59.2651757188498, Blast_Score=752, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 68520; Mature: 68520

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDNLRAAANHVVLKIILGLIILSFLLTGVVSYQGSAGDYAAKVNGQVIERAQLEQAFQS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHH
ERSRMQQQLGDQFSALAGNEGYMQQMRHQALSQLIDNMLLDQYAKKLGLSVSDDQVKEAI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RKAPYFQTNGQFDNAKYLDLISRMGYTADNFAQSMRQQLVNQQVIQAFGGSGFILPAEAQ
HHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
DMTALVLQQRDVRLATLDLKALQAKQTVTDDELKDYYSQNKNSFIAPEQVKVSYIPMDAA
HHHHHHHHHCCCEEEEEHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCHH
AMQDKVTVADADISAYYDQHKSSYGQPERKNYSVIQLKTEAEANAVLDELKKGGDFATLA
HHCCCEEEECCHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEC
KDKSTDIISRRTGGELGWLEPDTTADELKQANLTEKGQLSGVVKSSVGYLVIRLNDIAPE
CCCCCHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCH
KVKPLSEVRDAIAKQVKQEKAVDAYYALQQKVSEAATSDNESLASAEEAAGVKAAQTDWF
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHCCCCC
TRDNIPAALNFKPVIQSIFDGSLIGEGGSPGSNSDVITVDGDRAFVIRVSGHKPEGIEPF
CCCCCCCCCCHHHHHHHHHCCCEECCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCCHH
DQVKDRVAELVKRNKAEQEAKLQGEKLLVELKQGKGDEAMKAAGLSFGSVQKMARAPEDS
HHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHCCCCHH
QLVQSVFALPHPQEGKPVYGMSQDRQDNVVLIALDAVKPGTLPAEEMKTFVSKMEEGATG
HHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCC
VSFDSLLASLRKEAKITMGAAEQQQPQ
CCHHHHHHHHHHHHHEEECCCCCCCCC
>Mature Secondary Structure
MMDNLRAAANHVVLKIILGLIILSFLLTGVVSYQGSAGDYAAKVNGQVIERAQLEQAFQS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHH
ERSRMQQQLGDQFSALAGNEGYMQQMRHQALSQLIDNMLLDQYAKKLGLSVSDDQVKEAI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RKAPYFQTNGQFDNAKYLDLISRMGYTADNFAQSMRQQLVNQQVIQAFGGSGFILPAEAQ
HHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
DMTALVLQQRDVRLATLDLKALQAKQTVTDDELKDYYSQNKNSFIAPEQVKVSYIPMDAA
HHHHHHHHHCCCEEEEEHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCHH
AMQDKVTVADADISAYYDQHKSSYGQPERKNYSVIQLKTEAEANAVLDELKKGGDFATLA
HHCCCEEEECCHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEC
KDKSTDIISRRTGGELGWLEPDTTADELKQANLTEKGQLSGVVKSSVGYLVIRLNDIAPE
CCCCCHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCH
KVKPLSEVRDAIAKQVKQEKAVDAYYALQQKVSEAATSDNESLASAEEAAGVKAAQTDWF
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHCCCCC
TRDNIPAALNFKPVIQSIFDGSLIGEGGSPGSNSDVITVDGDRAFVIRVSGHKPEGIEPF
CCCCCCCCCCHHHHHHHHHCCCEECCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCCHH
DQVKDRVAELVKRNKAEQEAKLQGEKLLVELKQGKGDEAMKAAGLSFGSVQKMARAPEDS
HHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHCCCCHH
QLVQSVFALPHPQEGKPVYGMSQDRQDNVVLIALDAVKPGTLPAEEMKTFVSKMEEGATG
HHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCC
VSFDSLLASLRKEAKITMGAAEQQQPQ
CCHHHHHHHHHHHHHEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]