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The map label for this gene is secD [H]

Identifier: 157369306

GI number: 157369306

Start: 1169432

End: 1171279

Strand: Direct

Name: secD [H]

Synonym: Spro_1063

Alternate gene names: 157369306

Gene position: 1169432-1171279 (Clockwise)

Preceding gene: 157369305

Following gene: 157369307

Centisome position: 21.46

GC content: 57.79

Gene sequence:

>1848_bases
GTGCTAAACCGTTATCCTTTGTGGAAGTATCTGATGCTGATCGTAGTGATCATCATCGGTCTGCTTTATGCGCTTCCCAA
CCTCTATGGTGAGGATCCGGCTGTACAGATCACTGGCGCGCGCGGTGTCGCCGCCAGTGAAACTACGCTGGACCAAGTCC
GTACCGTATTAGAAAAAGACAAGATCGCGAGCAAGTCGATTGCGCTGGAAAATGGCGCCATCCTGGCTCGCTTTAGCAAT
CCTGATATTCAGCTGCGCGCGCGTGAAGCCTTAATGGCTGAGCTGGGCGACAAGTTCGTGGTGGCGCTGAACCTGGCCCC
GGCCACGCCGGCCTGGTTGGCCATGCTGGGCGCCGAACCGATGAAACTCGGTCTGGACCTGCGCGGTGGCGTGCACTTCC
TGATGGAAGTGGACATGGACACTGCGCTGAGCAAACTGCAGGAACAGACCATGGACACCCTGCGCAGCGAGCTGCGTGAA
AAGGGCATTCCTTATGCGTCTATCCGCAAGCTGGACAACAACGGCGTGGAAGTGCGTTTCCGTGACGATGCTGCCCGCGA
TCAGGCCATCAGCTACCTTGGCCCACGCCAACGTGACATGGTGTTCTCTGCCAACGGCACCAACACCCTGAAAGCCAACC
TGACGGATGCCCGCCTGAGCGAAGCGCGTGAGTATGCGGTGCAGCAGAACATCACTATCCTGCGTAACCGTGTTAACCAG
CTCGGCGTTGCCGAACCGCTGGTACAACGCCAGGGTTCTGACCGCATCGTGGTCGAACTGCCGGGTATTCAGGATACCGC
ACGTGCCAAAGAGATCCTGGGCGCTACCGCGACGCTGGAATTCCGTCTGGTTAACACCAATGCGGATACCACTGCGGCAG
CCAATGGCCGTGTGCCGGGTGACTCCGAAGTAAAAGACACCCGCGAAGGCCAGCCGGTTGTGCTGTACAAGCGCGTGATC
CTGACCGGTGACCACATTACCGACTCCACCTCCAGCACCGACGAATACAACCAGCCGCAGGTTAATATCTCGCTGGACAG
TACCGGCGGTACCGCGATGTCCAACTTCACCAAGGACAATATCGGCAAGCCGATGGCGACCCTGTTTGTGGAGTACAAGG
ACAGCGGCAAGAAAGACGCTAACGGCCGTGCAGTCCTGGTGAAACAGGAAGAAGTGATCAACGTGGCGAACATTCAGTCG
CGTCTGGGCAACAGCTTCCGTATTACCGGCATCGGCAACCCGAACGAAGCACGTCAGCTCTCGCTGCTGCTGCGCGCCGG
TGCGCTGATTGCGCCTATCCAGATCGTGGAAGAGCGGACAATCGGTCCGACCCTGGGGCAACAGAATATCACCCAAGGTC
TGGAAGCCTGCTTGTGGGGCCTGGTGGCATCCATCGTGTTTATGGTGGTTTGGTACCGTAAGTTCGGCATGATCGCTACC
ACGGCGCTGGTCGCCAACCTGGTGCTGATTGTCGGTGTCATGTCCCTGTTGCCGGGGGCGACGCTGACCATGCCGGGTAT
TGCCGGTATCGTGCTGACGCTGGCGGTGGCGGTCGACGCCAACGTACTGATCAATGAACGTATCAAGGAAGAGCTGAAGA
ACGGACGTTCCGTTCAGCAGGCGATCCATGAAGGCTATAAAGGCGCGTTCTCCAGTATCGTTGATGCCAACATCACCACC
CTGATCACCGCGATTATTCTGTACGCAGTGGGCACCGGTTCGATCAAAGGCTTTGCGATTACCACCGCAATCGGTGTGGC
GACGTCCATGTTCACCGCGATTGTCGGTACCCGTGCCATCGTCAACCTGCTTTACGGCGGCAAACGCATTAACAAGCTGT
CTATCTGA

Upstream 100 bases:

>100_bases
GACACCACGGAAGTGATGATCAAGCGTGACTTCGTGGCGGCCGTTCTGCCGAAAGGTACCATGAAGGCCCTGTAATTTTG
TTTTCCCGAAGGGAATTGCC

Downstream 100 bases:

>100_bases
GGAGTGCGTTGTGGCACAGGATTATACTGTTGAACAACTCAACTACGGCCGTAAAGTCTATGACTTTATGCGCTGGGATT
ACGTGGCCTTCGGCATCTCG

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MLNRYPLWKYLMLIVVIIIGLLYALPNLYGEDPAVQITGARGVAASETTLDQVRTVLEKDKIASKSIALENGAILARFSN
PDIQLRAREALMAELGDKFVVALNLAPATPAWLAMLGAEPMKLGLDLRGGVHFLMEVDMDTALSKLQEQTMDTLRSELRE
KGIPYASIRKLDNNGVEVRFRDDAARDQAISYLGPRQRDMVFSANGTNTLKANLTDARLSEAREYAVQQNITILRNRVNQ
LGVAEPLVQRQGSDRIVVELPGIQDTARAKEILGATATLEFRLVNTNADTTAAANGRVPGDSEVKDTREGQPVVLYKRVI
LTGDHITDSTSSTDEYNQPQVNISLDSTGGTAMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEVINVANIQS
RLGNSFRITGIGNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGQQNITQGLEACLWGLVASIVFMVVWYRKFGMIAT
TALVANLVLIVGVMSLLPGATLTMPGIAGIVLTLAVAVDANVLINERIKEELKNGRSVQQAIHEGYKGAFSSIVDANITT
LITAIILYAVGTGSIKGFAITTAIGVATSMFTAIVGTRAIVNLLYGGKRINKLSI

Sequences:

>Translated_615_residues
MLNRYPLWKYLMLIVVIIIGLLYALPNLYGEDPAVQITGARGVAASETTLDQVRTVLEKDKIASKSIALENGAILARFSN
PDIQLRAREALMAELGDKFVVALNLAPATPAWLAMLGAEPMKLGLDLRGGVHFLMEVDMDTALSKLQEQTMDTLRSELRE
KGIPYASIRKLDNNGVEVRFRDDAARDQAISYLGPRQRDMVFSANGTNTLKANLTDARLSEAREYAVQQNITILRNRVNQ
LGVAEPLVQRQGSDRIVVELPGIQDTARAKEILGATATLEFRLVNTNADTTAAANGRVPGDSEVKDTREGQPVVLYKRVI
LTGDHITDSTSSTDEYNQPQVNISLDSTGGTAMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEVINVANIQS
RLGNSFRITGIGNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGQQNITQGLEACLWGLVASIVFMVVWYRKFGMIAT
TALVANLVLIVGVMSLLPGATLTMPGIAGIVLTLAVAVDANVLINERIKEELKNGRSVQQAIHEGYKGAFSSIVDANITT
LITAIILYAVGTGSIKGFAITTAIGVATSMFTAIVGTRAIVNLLYGGKRINKLSI
>Mature_615_residues
MLNRYPLWKYLMLIVVIIIGLLYALPNLYGEDPAVQITGARGVAASETTLDQVRTVLEKDKIASKSIALENGAILARFSN
PDIQLRAREALMAELGDKFVVALNLAPATPAWLAMLGAEPMKLGLDLRGGVHFLMEVDMDTALSKLQEQTMDTLRSELRE
KGIPYASIRKLDNNGVEVRFRDDAARDQAISYLGPRQRDMVFSANGTNTLKANLTDARLSEAREYAVQQNITILRNRVNQ
LGVAEPLVQRQGSDRIVVELPGIQDTARAKEILGATATLEFRLVNTNADTTAAANGRVPGDSEVKDTREGQPVVLYKRVI
LTGDHITDSTSSTDEYNQPQVNISLDSTGGTAMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEVINVANIQS
RLGNSFRITGIGNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGQQNITQGLEACLWGLVASIVFMVVWYRKFGMIAT
TALVANLVLIVGVMSLLPGATLTMPGIAGIVLTLAVAVDANVLINERIKEELKNGRSVQQAIHEGYKGAFSSIVDANITT
LITAIILYAVGTGSIKGFAITTAIGVATSMFTAIVGTRAIVNLLYGGKRINKLSI

Specific function: Involved in protein export [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=615, Percent_Identity=83.5772357723577, Blast_Score=1055, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 66457; Mature: 66457

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNRYPLWKYLMLIVVIIIGLLYALPNLYGEDPAVQITGARGVAASETTLDQVRTVLEKD
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
KIASKSIALENGAILARFSNPDIQLRAREALMAELGDKFVVALNLAPATPAWLAMLGAEP
HHHHHHEEEECCEEEEEECCCCEEEHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCCC
MKLGLDLRGGVHFLMEVDMDTALSKLQEQTMDTLRSELREKGIPYASIRKLDNNGVEVRF
HHCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEECCCCCEEEE
RDDAARDQAISYLGPRQRDMVFSANGTNTLKANLTDARLSEAREYAVQQNITILRNRVNQ
CCCHHHHHHHHHCCCCCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGVAEPLVQRQGSDRIVVELPGIQDTARAKEILGATATLEFRLVNTNADTTAAANGRVPG
CCCHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCEEEEEEEEEECCCCCCCCCCCCCCC
DSEVKDTREGQPVVLYKRVILTGDHITDSTSSTDEYNQPQVNISLDSTGGTAMSNFTKDN
CCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHCCCHHH
IGKPMATLFVEYKDSGKKDANGRAVLVKQEEVINVANIQSRLGNSFRITGIGNPNEARQL
CCCCHHHEEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHH
SLLLRAGALIAPIQIVEERTIGPTLGQQNITQGLEACLWGLVASIVFMVVWYRKFGMIAT
HHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TALVANLVLIVGVMSLLPGATLTMPGIAGIVLTLAVAVDANVLINERIKEELKNGRSVQQ
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHH
AIHEGYKGAFSSIVDANITTLITAIILYAVGTGSIKGFAITTAIGVATSMFTAIVGTRAI
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
VNLLYGGKRINKLSI
HHHHHCCCCCCCCCC
>Mature Secondary Structure
MLNRYPLWKYLMLIVVIIIGLLYALPNLYGEDPAVQITGARGVAASETTLDQVRTVLEKD
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
KIASKSIALENGAILARFSNPDIQLRAREALMAELGDKFVVALNLAPATPAWLAMLGAEP
HHHHHHEEEECCEEEEEECCCCEEEHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCCC
MKLGLDLRGGVHFLMEVDMDTALSKLQEQTMDTLRSELREKGIPYASIRKLDNNGVEVRF
HHCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEECCCCCEEEE
RDDAARDQAISYLGPRQRDMVFSANGTNTLKANLTDARLSEAREYAVQQNITILRNRVNQ
CCCHHHHHHHHHCCCCCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGVAEPLVQRQGSDRIVVELPGIQDTARAKEILGATATLEFRLVNTNADTTAAANGRVPG
CCCHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCEEEEEEEEEECCCCCCCCCCCCCCC
DSEVKDTREGQPVVLYKRVILTGDHITDSTSSTDEYNQPQVNISLDSTGGTAMSNFTKDN
CCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHCCCHHH
IGKPMATLFVEYKDSGKKDANGRAVLVKQEEVINVANIQSRLGNSFRITGIGNPNEARQL
CCCCHHHEEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHH
SLLLRAGALIAPIQIVEERTIGPTLGQQNITQGLEACLWGLVASIVFMVVWYRKFGMIAT
HHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TALVANLVLIVGVMSLLPGATLTMPGIAGIVLTLAVAVDANVLINERIKEELKNGRSVQQ
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHH
AIHEGYKGAFSSIVDANITTLITAIILYAVGTGSIKGFAITTAIGVATSMFTAIVGTRAI
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
VNLLYGGKRINKLSI
HHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]