Click here to switch to the map view.

The map label for this gene is hofB [H]

Identifier: 157369022

GI number: 157369022

Start: 866256

End: 867701

Strand: Reverse

Name: hofB [H]

Synonym: Spro_0777

Alternate gene names: 157369022

Gene position: 867701-866256 (Counterclockwise)

Preceding gene: 157369023

Following gene: 157369021

Centisome position: 15.92

GC content: 58.78

Gene sequence:

>1446_bases
ATGAGTACGGCAATCAGTGACGAAATCCATGCGCTGTGCCGCCGTTATCAGGCACTGGCTCTCAGCGAAGATCGGTACTG
CCTGAATGTGGCCCTGACTACGGAGGCGCCAGAGGCGCTGCTGTCGGCGCTGCGTTTCGCCACCGGCAAGCGCATTCATC
TGGAACAGTGGCCGGCCGCCCGGCTGGAAATGGAACTGAACCAACGACAAATACAAGGCGATCGACTCCCGCAAGAAGTG
CCGGAGACACAACCTGATGCACCCTCATTAAACGACGACAGCGACGCTCCCGTTGTGCAGTTTATCAATCAGACGCTGCG
CATCGCCATTCAACGGCGTGCCTCGGATATTCATTTCGAGCCTTACCAACAGACGCTACGTATCCGCCTGCGGATCGACG
GGGTACTGCAGGCGATAACCTCACCGCCATTCACGCTCGCCGCTCGCCTCATCGCCCGACTGAAGATCATGGGGCAGTTG
GACATTGCCGAACGTCGCCTGCCACAGGATGGTCAGCTCAGCGTGCAATTGGATAACGCCAGTTACTCGATGCGCATCGC
CACCCTGCCCACGCTGCACGGCGAAAAAGTGGTGCTGCGAGTCCTGCAAACCGAACGCCAGGAGCTACCGCTGGATCGGC
TGGGAATGGATCCGCCGGCGTTGGCGGAGTTTGCCGCGGCATTGTCCTGTCCACAGGGTATGATCCTGGTCACCGGCCCG
ACCGGCAGTGGTAAAACCGTGACGCTTTACAGCGGCCTGCGTCAGTTGAATGATGCGCAAAGTAATTTATGCAGCGTCGA
GGATCCGATCGAGATCCCGTTGTTTGGCGTTAACCAGACGCAAATTAATGCCAAAACCGACCTGGATTTTTCCCGCGTTT
TACGCGCCTTACTGCGACAAGATCCGGACGTGATCATGATCGGTGAAATCCGCGACAGGGAAACGGCAGAGATCGCGGTT
AAAGCCGCGCAAACCGGCCATCTGGTGCTATCCACATTGCACACCAACTCCACCAGCGAAACCCTGACGCGCCTGACCCA
TATGGGGATTCCCGGCTATCTGATTGCCGCCTGCCTGAAGCTGGTGATAGCCCAGCGGCTGGTGCGCAAACTTTGCAGCC
ACTGCCGCTATCAGCAAAGCCAGCCCGTACGCTTCCCTGCCGCCATTTGGGCCACGCCCCTGCTGCCCTGGCAGGCTGAT
GGTTGCGAACACTGCTTTAGCGGCTACTACGGCCGCACCGGGGTATATGAATTACTGACTATCACCCCAGAGGTGCAGGC
CGGGCTGTTACGGAGCGCCGCTCCTGGTGAACTGGCCGACATCGCCCAACAGCAAGGGCAGACAACGCTGCTGCAAGCCG
GATTAACGCTGGTTTCACAAGGCGTCACATCGCTGGAAGAGGTATACCGTATTGTCGGCATCATTGCCGGTGAGGAGGCA
CCGTGA

Upstream 100 bases:

>100_bases
TGACCCGTTGGACACGTCAGTGCACCAGCAGCAACGCCAATCTGCAGGAAACCTGTCAGGAAGTTTTCCGTTTTGACGCC
ACCGCAACGGCACCAACGCC

Downstream 100 bases:

>100_bases
AAGCGCTGCGCCTTTTCCTCTGGCAGGCGATTGACCCTCTGGGTCAACTGCGTCAGGGCGAACTGATGTGCAGCGAAAAG
AATTTGGTCAGCCACTGGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MSTAISDEIHALCRRYQALALSEDRYCLNVALTTEAPEALLSALRFATGKRIHLEQWPAARLEMELNQRQIQGDRLPQEV
PETQPDAPSLNDDSDAPVVQFINQTLRIAIQRRASDIHFEPYQQTLRIRLRIDGVLQAITSPPFTLAARLIARLKIMGQL
DIAERRLPQDGQLSVQLDNASYSMRIATLPTLHGEKVVLRVLQTERQELPLDRLGMDPPALAEFAAALSCPQGMILVTGP
TGSGKTVTLYSGLRQLNDAQSNLCSVEDPIEIPLFGVNQTQINAKTDLDFSRVLRALLRQDPDVIMIGEIRDRETAEIAV
KAAQTGHLVLSTLHTNSTSETLTRLTHMGIPGYLIAACLKLVIAQRLVRKLCSHCRYQQSQPVRFPAAIWATPLLPWQAD
GCEHCFSGYYGRTGVYELLTITPEVQAGLLRSAAPGELADIAQQQGQTTLLQAGLTLVSQGVTSLEEVYRIVGIIAGEEA
P

Sequences:

>Translated_481_residues
MSTAISDEIHALCRRYQALALSEDRYCLNVALTTEAPEALLSALRFATGKRIHLEQWPAARLEMELNQRQIQGDRLPQEV
PETQPDAPSLNDDSDAPVVQFINQTLRIAIQRRASDIHFEPYQQTLRIRLRIDGVLQAITSPPFTLAARLIARLKIMGQL
DIAERRLPQDGQLSVQLDNASYSMRIATLPTLHGEKVVLRVLQTERQELPLDRLGMDPPALAEFAAALSCPQGMILVTGP
TGSGKTVTLYSGLRQLNDAQSNLCSVEDPIEIPLFGVNQTQINAKTDLDFSRVLRALLRQDPDVIMIGEIRDRETAEIAV
KAAQTGHLVLSTLHTNSTSETLTRLTHMGIPGYLIAACLKLVIAQRLVRKLCSHCRYQQSQPVRFPAAIWATPLLPWQAD
GCEHCFSGYYGRTGVYELLTITPEVQAGLLRSAAPGELADIAQQQGQTTLLQAGLTLVSQGVTSLEEVYRIVGIIAGEEA
P
>Mature_480_residues
STAISDEIHALCRRYQALALSEDRYCLNVALTTEAPEALLSALRFATGKRIHLEQWPAARLEMELNQRQIQGDRLPQEVP
ETQPDAPSLNDDSDAPVVQFINQTLRIAIQRRASDIHFEPYQQTLRIRLRIDGVLQAITSPPFTLAARLIARLKIMGQLD
IAERRLPQDGQLSVQLDNASYSMRIATLPTLHGEKVVLRVLQTERQELPLDRLGMDPPALAEFAAALSCPQGMILVTGPT
GSGKTVTLYSGLRQLNDAQSNLCSVEDPIEIPLFGVNQTQINAKTDLDFSRVLRALLRQDPDVIMIGEIRDRETAEIAVK
AAQTGHLVLSTLHTNSTSETLTRLTHMGIPGYLIAACLKLVIAQRLVRKLCSHCRYQQSQPVRFPAAIWATPLLPWQADG
CEHCFSGYYGRTGVYELLTITPEVQAGLLRSAAPGELADIAQQQGQTTLLQAGLTLVSQGVTSLEEVYRIVGIIAGEEAP

Specific function: Unknown

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1786296, Length=471, Percent_Identity=51.5923566878981, Blast_Score=462, Evalue=1e-131,
Organism=Escherichia coli, GI1789723, Length=438, Percent_Identity=44.2922374429224, Blast_Score=360, Evalue=1e-100,
Organism=Escherichia coli, GI87082188, Length=307, Percent_Identity=32.2475570032573, Blast_Score=105, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007831
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E; PF05157 GSPII_E_N [H]

EC number: NA

Molecular weight: Translated: 53014; Mature: 52882

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00093 N4_MTASE ; PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAISDEIHALCRRYQALALSEDRYCLNVALTTEAPEALLSALRFATGKRIHLEQWPAA
CCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHCCCEEEECCCCCH
RLEMELNQRQIQGDRLPQEVPETQPDAPSLNDDSDAPVVQFINQTLRIAIQRRASDIHFE
HHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
PYQQTLRIRLRIDGVLQAITSPPFTLAARLIARLKIMGQLDIAERRLPQDGQLSVQLDNA
CHHHEEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEECCC
SYSMRIATLPTLHGEKVVLRVLQTERQELPLDRLGMDPPALAEFAAALSCPQGMILVTGP
CEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHCCCCCEEEEECC
TGSGKTVTLYSGLRQLNDAQSNLCSVEDPIEIPLFGVNQTQINAKTDLDFSRVLRALLRQ
CCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEECCCCCCCHHHHHHHHHHC
DPDVIMIGEIRDRETAEIAVKAAQTGHLVLSTLHTNSTSETLTRLTHMGIPGYLIAACLK
CCCEEEECCCCCCCHHHHEEEECCCCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHH
LVIAQRLVRKLCSHCRYQQSQPVRFPAAIWATPLLPWQADGCEHCFSGYYGRTGVYELLT
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHCCCCCCCCCEEEEE
ITPEVQAGLLRSAAPGELADIAQQQGQTTLLQAGLTLVSQGVTSLEEVYRIVGIIAGEEA
ECHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
P
C
>Mature Secondary Structure 
STAISDEIHALCRRYQALALSEDRYCLNVALTTEAPEALLSALRFATGKRIHLEQWPAA
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHCCCEEEECCCCCH
RLEMELNQRQIQGDRLPQEVPETQPDAPSLNDDSDAPVVQFINQTLRIAIQRRASDIHFE
HHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
PYQQTLRIRLRIDGVLQAITSPPFTLAARLIARLKIMGQLDIAERRLPQDGQLSVQLDNA
CHHHEEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEECCC
SYSMRIATLPTLHGEKVVLRVLQTERQELPLDRLGMDPPALAEFAAALSCPQGMILVTGP
CEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHCCCCCEEEEECC
TGSGKTVTLYSGLRQLNDAQSNLCSVEDPIEIPLFGVNQTQINAKTDLDFSRVLRALLRQ
CCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEECCCCCCCHHHHHHHHHHC
DPDVIMIGEIRDRETAEIAVKAAQTGHLVLSTLHTNSTSETLTRLTHMGIPGYLIAACLK
CCCEEEECCCCCCCHHHHEEEECCCCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHH
LVIAQRLVRKLCSHCRYQQSQPVRFPAAIWATPLLPWQADGCEHCFSGYYGRTGVYELLT
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHCCCCCCCCCEEEEE
ITPEVQAGLLRSAAPGELADIAQQQGQTTLLQAGLTLVSQGVTSLEEVYRIVGIIAGEEA
ECHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7959070; 8202364; 9278503 [H]