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The map label for this gene is ttuB [H]

Identifier: 157368954

GI number: 157368954

Start: 782665

End: 784053

Strand: Reverse

Name: ttuB [H]

Synonym: Spro_0709

Alternate gene names: 157368954

Gene position: 784053-782665 (Counterclockwise)

Preceding gene: 157368955

Following gene: 157368953

Centisome position: 14.39

GC content: 54.21

Gene sequence:

>1389_bases
ATGAAGTTGACGATGGAAAAGCAGACGGTGAAGCAAACCGCTGAAACGCAGGTCTACGGTAAGATCACACGCCGCCTGAT
CCCTTTTTTGATCCTGTGTTATTTCTTCGCTTACCTGGACCGCGTTAACGTCGGGTTCGCCAAGCTGCACATGCAGGATG
CCCTGAATTTCAGCGATACCGTTTATGGCCTGGGCGCCGGTATCTTCTTCATTGGTTATTTTATTTTTGAGTTGCCCAGC
AATCTGCTGATGCAACGTTTTGGGCCACGATTCTGGATAGCCCGCATCATGGCGACCTGGGCAGTACTGTCAGCGGCCAT
GATGTTTGTCACCACCCCTACCAGCTTTTACGTATTGCGCTTTCTGCTCGGCGTGGCCGAAGCCGGCTTCTTCCCAGGCA
TCGTGTTCTATTTAACCCTGTGGTTTCCTTCATGGCGTTCCGCCCGCACGCTGGGGCTGTTTATTCTGGTCACGCCGCTG
TCGGTGATCATCGGCAGCCCGCTTTCAGGTTTGATCCTCAAGCTGTTTGAAAACGTCGGCGGCTTGCATAACTGGCAGTG
GCTGTTCTTGATTGAAGCGGTCCCATCTTTGGTTCTGGCCTTTGTGGTGTTGCGTTACCTGGATAACAATGTGGCCGAAG
CCAAATGGTTAACTGCCGCAGAGAAAAACCTGGTGCAGGCCGATCTGGCTAAAGATCAGGCCAACCGCGACCGGGCGGCC
AACGGCAAAGCGGCTCACAGTCTCAAAGAGATGCTGGCTAACCGCTACGTCTGGCTATTGGCATTGATTTTCTTCAGTTT
TAATGTCGGCTACTACGGCATCAGTTTCTGGCTACCTTCCATCATCAAAACCTCAGGTATCAGCGACGATTTGCAAATCG
GCCTGCTGGCGGCCCTGCCCTACGTATTTGGCGCACTGTTTATGATATGGAACAGCCGACACTCCGATTTGAAACAGGAG
CGCCGTTGGCATATTGCCATTCCGGCGGTGATTGGCTGTATCGGGCTGACACTCAGCGCTTACTGCAGCGGCTCGACCTT
CTGGATGATGACGTGGATCTGCGTTGCCATGTCCGGCACCCTGGCGCTGATCCCCACCTATATCAGCCTGCCGGGCGCAT
TGCTTTCCGGCACTGCGGCGGCGGCCGGTATCGCACTGGTGAATTCGGTCGGCAATCTCGCGGGGTTCTTCGGCCCCACG
GTACTCGGCTGGCTGAAAGACCAAACCGGCCAGACTGACAGTGGACTGTATATTTTGGCGGGCTTCCTGCTGCTGTGCGC
CCCGTTGATCTTCATGCTTCCGGCCAGATTGATAAACCCAAAGATCAAACCGCATCAGGCGACTCAGCCTGATACCGAAG
GCCCTTTAAATATCACTGAGAGATTTTAA

Upstream 100 bases:

>100_bases
GTTGCCCTGCGCCACATCGGCAAATCACCGCAGCCGAAGGCTGATGTTCGCTCCTTGAATACGCCGGTATAACCCGACTA
ATAAATCTGAGGAACCGCTC

Downstream 100 bases:

>100_bases
TTATGAGCGGATGTGGAACCTGTGGCGGCGGCAGTTGCGGCGCGCATTTTAACCCAATCCTCGAGGGTGATGACGGTGCG
CTGAAACGTGCGCTGTATAA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MKLTMEKQTVKQTAETQVYGKITRRLIPFLILCYFFAYLDRVNVGFAKLHMQDALNFSDTVYGLGAGIFFIGYFIFELPS
NLLMQRFGPRFWIARIMATWAVLSAAMMFVTTPTSFYVLRFLLGVAEAGFFPGIVFYLTLWFPSWRSARTLGLFILVTPL
SVIIGSPLSGLILKLFENVGGLHNWQWLFLIEAVPSLVLAFVVLRYLDNNVAEAKWLTAAEKNLVQADLAKDQANRDRAA
NGKAAHSLKEMLANRYVWLLALIFFSFNVGYYGISFWLPSIIKTSGISDDLQIGLLAALPYVFGALFMIWNSRHSDLKQE
RRWHIAIPAVIGCIGLTLSAYCSGSTFWMMTWICVAMSGTLALIPTYISLPGALLSGTAAAAGIALVNSVGNLAGFFGPT
VLGWLKDQTGQTDSGLYILAGFLLLCAPLIFMLPARLINPKIKPHQATQPDTEGPLNITERF

Sequences:

>Translated_462_residues
MKLTMEKQTVKQTAETQVYGKITRRLIPFLILCYFFAYLDRVNVGFAKLHMQDALNFSDTVYGLGAGIFFIGYFIFELPS
NLLMQRFGPRFWIARIMATWAVLSAAMMFVTTPTSFYVLRFLLGVAEAGFFPGIVFYLTLWFPSWRSARTLGLFILVTPL
SVIIGSPLSGLILKLFENVGGLHNWQWLFLIEAVPSLVLAFVVLRYLDNNVAEAKWLTAAEKNLVQADLAKDQANRDRAA
NGKAAHSLKEMLANRYVWLLALIFFSFNVGYYGISFWLPSIIKTSGISDDLQIGLLAALPYVFGALFMIWNSRHSDLKQE
RRWHIAIPAVIGCIGLTLSAYCSGSTFWMMTWICVAMSGTLALIPTYISLPGALLSGTAAAAGIALVNSVGNLAGFFGPT
VLGWLKDQTGQTDSGLYILAGFLLLCAPLIFMLPARLINPKIKPHQATQPDTEGPLNITERF
>Mature_462_residues
MKLTMEKQTVKQTAETQVYGKITRRLIPFLILCYFFAYLDRVNVGFAKLHMQDALNFSDTVYGLGAGIFFIGYFIFELPS
NLLMQRFGPRFWIARIMATWAVLSAAMMFVTTPTSFYVLRFLLGVAEAGFFPGIVFYLTLWFPSWRSARTLGLFILVTPL
SVIIGSPLSGLILKLFENVGGLHNWQWLFLIEAVPSLVLAFVVLRYLDNNVAEAKWLTAAEKNLVQADLAKDQANRDRAA
NGKAAHSLKEMLANRYVWLLALIFFSFNVGYYGISFWLPSIIKTSGISDDLQIGLLAALPYVFGALFMIWNSRHSDLKQE
RRWHIAIPAVIGCIGLTLSAYCSGSTFWMMTWICVAMSGTLALIPTYISLPGALLSGTAAAAGIALVNSVGNLAGFFGPT
VLGWLKDQTGQTDSGLYILAGFLLLCAPLIFMLPARLINPKIKPHQATQPDTEGPLNITERF

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=418, Percent_Identity=36.3636363636364, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI2367379, Length=410, Percent_Identity=25.8536585365854, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1789515, Length=460, Percent_Identity=22.1739130434783, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789152, Length=445, Percent_Identity=22.9213483146067, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322025, Length=249, Percent_Identity=27.3092369477912, Blast_Score=83, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6321698, Length=283, Percent_Identity=22.6148409893993, Blast_Score=73, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6319876, Length=328, Percent_Identity=22.8658536585366, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6324410, Length=160, Percent_Identity=26.25, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323032, Length=332, Percent_Identity=23.7951807228916, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 51296; Mature: 51296

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]