Click here to switch to the map view.

The map label for this gene is hflX [H]

Identifier: 157368679

GI number: 157368679

Start: 483573

End: 484853

Strand: Direct

Name: hflX [H]

Synonym: Spro_0432

Alternate gene names: 157368679

Gene position: 483573-484853 (Clockwise)

Preceding gene: 157368678

Following gene: 157368680

Centisome position: 8.87

GC content: 54.8

Gene sequence:

>1281_bases
TTGTTTGACCGTTATGAAGCCGGTGAGCAGGCCGTCCTGGTTCATATCTATTTCTCGCAAGACAAAGATACAGAAGATCT
CAGTGAGTTCGAATCCCTGGTGTCCTCTGCGGGTGTCGAAGCTTTGCAAGTGGTGACTGGTAGCCGCAAAGCCCCACATC
CCAAGTACTTTGTCGGTGAAGGAAAGGCCGAAGAAATTGCAGATGCGGTAAAAGCCAGTGGCGCATCTGTTGTCCTGTTT
GATCACTCCCTTTCCGCGGCGCAAGAGAGAAACCTTGAACGCCTGTGCGAATGCCGGGTGATCGATCGCACCGGGTTGAT
TCTAGACATCTTTGCCCAGCGTGCCCGTACCCATGAAGGTAAGCTGCAGGTAGAGCTGGCGCAGTTGCGTCATATCGCCA
CGCGTTTAGTTCGTGGCTGGACGCACCTTGAGCGCCAAAAAGGGGGGATTGGCCTGCGCGGGCCAGGGGAAACCCAATTA
GAGACCGACCGTCGTCTGTTACGCGATCGCATTAGCCTGATTCTACGCCGCCTGGAGCGGGTAGCTAAGCAGCGTGAACA
GGGCCGACGTGCGCGTACCCGTGCCGAAGTGCCAACCGTATCGCTGGTGGGATACACCAACGCCGGTAAATCTACCCTGT
TTAATCGAATAACGTCTGCCGATGTGTACGCGGCCGACCAGCTATTTGCCACCCTGGATCCTACCCTGCGGCGTATCGAC
GTGGCCGATGTGGGCGATACCGTGTTGGCGGATACCGTAGGCTTTATCCGGCACCTGCCGCACGATCTGGTGGCCGCCTT
CAAGGCAACGCTGCAAGAAACGCGTCAGGCATCTTTGCTGTTACATGTAATCGACGCCGCGGATACCCGTGTCGATGAGA
ACATTGAAGCGGTAAATACCGTGCTGGCAGAGATTGAATCGGATGAGATCCCTACACTGTTAGTGATGAACAAAATAGAT
ATGCTGGATGATTTTGTTCCGCGTATCGACCGCAACGATGAAAACTTACCGATCCGGGTGTGGCTGTCCGCCGCCAGCGG
TGAAGGTATCCCGTTGCTGTATCAGGCGTTGACGGAGCGCTTATCGGGGGAAATCGCGCATTATGAGCTGCGCTTACCGC
CAGAGGCAGGCCGTCTTCGTAGCCGTTTTTACCAGCTTCAGGCAATTGAGAAAGAGTGGAACGAAGAAGACGGCAGCATT
GGCGTGGTGGTTCGTATGCCTATCGTCGAATGGCGTCGCCTCTGCAAACAGGAACTGGATCTGATTAACTTTATAGTATG
A

Upstream 100 bases:

>100_bases
AATAAAGCGCGTTGCGAGTCAACCATGACGGGGAGCATAAGCAGCCGTGGGCTGTTTATGTCCCCCAAACTCACGGATTT
CCGTTTGAGAGGTTGCACGC

Downstream 100 bases:

>100_bases
TCATATCCTGTTACATTTGAGCTTCGCGTAAGCCTGAAGTACCCAATCACAGAATATGGAGCTAAAACATGGCGTGGAAT
CAGCCCGGTAATAACGGACA

Product: putative GTPase HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MFDRYEAGEQAVLVHIYFSQDKDTEDLSEFESLVSSAGVEALQVVTGSRKAPHPKYFVGEGKAEEIADAVKASGASVVLF
DHSLSAAQERNLERLCECRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHIATRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRDRISLILRRLERVAKQREQGRRARTRAEVPTVSLVGYTNAGKSTLFNRITSADVYAADQLFATLDPTLRRID
VADVGDTVLADTVGFIRHLPHDLVAAFKATLQETRQASLLLHVIDAADTRVDENIEAVNTVLAEIESDEIPTLLVMNKID
MLDDFVPRIDRNDENLPIRVWLSAASGEGIPLLYQALTERLSGEIAHYELRLPPEAGRLRSRFYQLQAIEKEWNEEDGSI
GVVVRMPIVEWRRLCKQELDLINFIV

Sequences:

>Translated_426_residues
MFDRYEAGEQAVLVHIYFSQDKDTEDLSEFESLVSSAGVEALQVVTGSRKAPHPKYFVGEGKAEEIADAVKASGASVVLF
DHSLSAAQERNLERLCECRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHIATRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRDRISLILRRLERVAKQREQGRRARTRAEVPTVSLVGYTNAGKSTLFNRITSADVYAADQLFATLDPTLRRID
VADVGDTVLADTVGFIRHLPHDLVAAFKATLQETRQASLLLHVIDAADTRVDENIEAVNTVLAEIESDEIPTLLVMNKID
MLDDFVPRIDRNDENLPIRVWLSAASGEGIPLLYQALTERLSGEIAHYELRLPPEAGRLRSRFYQLQAIEKEWNEEDGSI
GVVVRMPIVEWRRLCKQELDLINFIV
>Mature_426_residues
MFDRYEAGEQAVLVHIYFSQDKDTEDLSEFESLVSSAGVEALQVVTGSRKAPHPKYFVGEGKAEEIADAVKASGASVVLF
DHSLSAAQERNLERLCECRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHIATRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRDRISLILRRLERVAKQREQGRRARTRAEVPTVSLVGYTNAGKSTLFNRITSADVYAADQLFATLDPTLRRID
VADVGDTVLADTVGFIRHLPHDLVAAFKATLQETRQASLLLHVIDAADTRVDENIEAVNTVLAEIESDEIPTLLVMNKID
MLDDFVPRIDRNDENLPIRVWLSAASGEGIPLLYQALTERLSGEIAHYELRLPPEAGRLRSRFYQLQAIEKEWNEEDGSI
GVVVRMPIVEWRRLCKQELDLINFIV

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=225, Percent_Identity=34.2222222222222, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI310133116, Length=222, Percent_Identity=34.6846846846847, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI310124269, Length=204, Percent_Identity=35.2941176470588, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI310124267, Length=204, Percent_Identity=35.2941176470588, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI310124171, Length=204, Percent_Identity=35.2941176470588, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI310124169, Length=204, Percent_Identity=35.2941176470588, Blast_Score=112, Evalue=5e-25,
Organism=Escherichia coli, GI1790615, Length=426, Percent_Identity=85.6807511737089, Blast_Score=749, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561038, Length=286, Percent_Identity=28.3216783216783, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24650079, Length=284, Percent_Identity=30.6338028169014, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47974; Mature: 47974

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRYEAGEQAVLVHIYFSQDKDTEDLSEFESLVSSAGVEALQVVTGSRKAPHPKYFVGE
CCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEECC
GKAEEIADAVKASGASVVLFDHSLSAAQERNLERLCECRVIDRTGLILDIFAQRARTHEG
CCHHHHHHHHHCCCCEEEEEECCHHHHHHCCHHHHHHHEEECCCCHHHHHHHHHHHCCCC
KLQVELAQLRHIATRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRDRISLILRRLER
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VAKQREQGRRARTRAEVPTVSLVGYTNAGKSTLFNRITSADVYAADQLFATLDPTLRRID
HHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHCHHHHEEE
VADVGDTVLADTVGFIRHLPHDLVAAFKATLQETRQASLLLHVIDAADTRVDENIEAVNT
HHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VLAEIESDEIPTLLVMNKIDMLDDFVPRIDRNDENLPIRVWLSAASGEGIPLLYQALTER
HHHHHCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHH
LSGEIAHYELRLPPEAGRLRSRFYQLQAIEKEWNEEDGSIGVVVRMPIVEWRRLCKQELD
HCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHH
LINFIV
HHHHCC
>Mature Secondary Structure
MFDRYEAGEQAVLVHIYFSQDKDTEDLSEFESLVSSAGVEALQVVTGSRKAPHPKYFVGE
CCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEECC
GKAEEIADAVKASGASVVLFDHSLSAAQERNLERLCECRVIDRTGLILDIFAQRARTHEG
CCHHHHHHHHHCCCCEEEEEECCHHHHHHCCHHHHHHHEEECCCCHHHHHHHHHHHCCCC
KLQVELAQLRHIATRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRDRISLILRRLER
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VAKQREQGRRARTRAEVPTVSLVGYTNAGKSTLFNRITSADVYAADQLFATLDPTLRRID
HHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHCHHHHEEE
VADVGDTVLADTVGFIRHLPHDLVAAFKATLQETRQASLLLHVIDAADTRVDENIEAVNT
HHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VLAEIESDEIPTLLVMNKIDMLDDFVPRIDRNDENLPIRVWLSAASGEGIPLLYQALTER
HHHHHCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHH
LSGEIAHYELRLPPEAGRLRSRFYQLQAIEKEWNEEDGSIGVVVRMPIVEWRRLCKQELD
HCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHH
LINFIV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]