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The map label for this gene is nudC [H]

Identifier: 157368535

GI number: 157368535

Start: 328515

End: 329282

Strand: Direct

Name: nudC [H]

Synonym: Spro_0286

Alternate gene names: 157368535

Gene position: 328515-329282 (Clockwise)

Preceding gene: 157368527

Following gene: 157368536

Centisome position: 6.03

GC content: 57.68

Gene sequence:

>768_bases
ATGGAACTTGCATTAACGGGTAATGAAAATGGCTGGTGGATCGTCAGCCATGAAAGCAAACTTTGGTTACCGAACGGTGA
ATTGCCGTGCGGTTTGGCCGCGTCATTTTCCCTGCTGGGAAGAATGGCTCGTGTTATTGGCGAATGGGAAGGATTGCCGG
TCTGGCTGGTGCGCCACGCAATGCCGCAGGAGATGGGATCGGTACGCCAACTGTTAGAACTGGATCGCGGGCTGTTCCAG
CTTGCCGGACGGGGCGTACAACTGGCCGAGTTTTACCGTTCCCATCGCTACTGCGGTTACTGCGGCCATGAAATGCATCT
CAGCCGCACCGAAAGTGCCTGCCTGTGCGGCCACTGCCGGGAGCGCTACTACCCGCAGATCGCCCCCTGCGTGATCGTTG
CCATTCGGCGTGACGATGAGATCCTGCTGGCACAACATGTGCGCCATCGCGGCGGTATTCATACCGTACTGGCCGGCTTT
GTCGAGGTTGGCGAAACGCTGGAGCAGGCGGCCGCACGCGAGGTGATGGAAGAAAGTAATATTGAAATCAAAAACCTGCG
TTATGTCACCTCACAACCCTGGCCGTTCCCGCACTCGTTGATGATGGCCTTTATGGCCGATTACCACCGCGGCGAGATCC
GTCACGATCCGAAAGAGCTGCTTAACGCCGGTTGGTACCGCTACGATCGGTTGCCGCTATTACCGCCGCCCGGCACGGTA
GCGCGTCGCCTGATAGAGGACACCGTAGCCTTATGCCGTGAGCAATAA

Upstream 100 bases:

>100_bases
TGTTTGACTCCGTAAGTAATAAAACGTAACAGTAAGTTATTAAAATGTAACAAGGCCGATTTGTAGAGTGCCAGTGAAGC
TGAGGTTGTGCAACAACGAT

Downstream 100 bases:

>100_bases
ATCGCTACAATACCGGCAGATGAATAAGGGAGCCCCATAAATGAATGAGTTGAAGAACGATCGCTACCTGCGCGCACTGC
TGCGTCAGCCGGTGGATGTG

Product: NADH pyrophosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MELALTGNENGWWIVSHESKLWLPNGELPCGLAASFSLLGRMARVIGEWEGLPVWLVRHAMPQEMGSVRQLLELDRGLFQ
LAGRGVQLAEFYRSHRYCGYCGHEMHLSRTESACLCGHCRERYYPQIAPCVIVAIRRDDEILLAQHVRHRGGIHTVLAGF
VEVGETLEQAAAREVMEESNIEIKNLRYVTSQPWPFPHSLMMAFMADYHRGEIRHDPKELLNAGWYRYDRLPLLPPPGTV
ARRLIEDTVALCREQ

Sequences:

>Translated_255_residues
MELALTGNENGWWIVSHESKLWLPNGELPCGLAASFSLLGRMARVIGEWEGLPVWLVRHAMPQEMGSVRQLLELDRGLFQ
LAGRGVQLAEFYRSHRYCGYCGHEMHLSRTESACLCGHCRERYYPQIAPCVIVAIRRDDEILLAQHVRHRGGIHTVLAGF
VEVGETLEQAAAREVMEESNIEIKNLRYVTSQPWPFPHSLMMAFMADYHRGEIRHDPKELLNAGWYRYDRLPLLPPPGTV
ARRLIEDTVALCREQ
>Mature_255_residues
MELALTGNENGWWIVSHESKLWLPNGELPCGLAASFSLLGRMARVIGEWEGLPVWLVRHAMPQEMGSVRQLLELDRGLFQ
LAGRGVQLAEFYRSHRYCGYCGHEMHLSRTESACLCGHCRERYYPQIAPCVIVAIRRDDEILLAQHVRHRGGIHTVLAGF
VEVGETLEQAAAREVMEESNIEIKNLRYVTSQPWPFPHSLMMAFMADYHRGEIRHDPKELLNAGWYRYDRLPLLPPPGTV
ARRLIEDTVALCREQ

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI50593112, Length=171, Percent_Identity=33.9181286549708, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI13899267, Length=203, Percent_Identity=29.5566502463054, Blast_Score=93, Evalue=2e-19,
Organism=Escherichia coli, GI48994995, Length=255, Percent_Identity=74.9019607843137, Blast_Score=403, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI212645999, Length=152, Percent_Identity=32.8947368421053, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71986510, Length=152, Percent_Identity=32.8947368421053, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321371, Length=170, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376 [H]

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase [H]

EC number: =3.6.1.22 [H]

Molecular weight: Translated: 29184; Mature: 29184

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELALTGNENGWWIVSHESKLWLPNGELPCGLAASFSLLGRMARVIGEWEGLPVWLVRHA
CEEEEECCCCCEEEEECCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
MPQEMGSVRQLLELDRGLFQLAGRGVQLAEFYRSHRYCGYCGHEMHLSRTESACLCGHCR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHECCCCHHHHHHHHHH
ERYYPQIAPCVIVAIRRDDEILLAQHVRHRGGIHTVLAGFVEVGETLEQAAAREVMEESN
HHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IEIKNLRYVTSQPWPFPHSLMMAFMADYHRGEIRHDPKELLNAGWYRYDRLPLLPPPGTV
CEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEECCCCCCCCCHHH
ARRLIEDTVALCREQ
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MELALTGNENGWWIVSHESKLWLPNGELPCGLAASFSLLGRMARVIGEWEGLPVWLVRHA
CEEEEECCCCCEEEEECCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
MPQEMGSVRQLLELDRGLFQLAGRGVQLAEFYRSHRYCGYCGHEMHLSRTESACLCGHCR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHECCCCHHHHHHHHHH
ERYYPQIAPCVIVAIRRDDEILLAQHVRHRGGIHTVLAGFVEVGETLEQAAAREVMEESN
HHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IEIKNLRYVTSQPWPFPHSLMMAFMADYHRGEIRHDPKELLNAGWYRYDRLPLLPPPGTV
CEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEECCCCCCCCCHHH
ARRLIEDTVALCREQ
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA