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The map label for this gene is hpaA [C]

Identifier: 157163793

GI number: 157163793

Start: 4586007

End: 4586897

Strand: Reverse

Name: hpaA [C]

Synonym: EcHS_A4577

Alternate gene names: 157163793

Gene position: 4586897-4586007 (Counterclockwise)

Preceding gene: 157163794

Following gene: 157163792

Centisome position: 98.78

GC content: 52.64

Gene sequence:

>891_bases
ATGTGTGACCGTCAGATTGCCAATATTGATATCAGCAAAGAGTACGATGAAAGCCTGGGCACGGACGATGTGCATTATCA
GTCCTTCGCCCGCATGGCGGCATTTTTTGGCCGCCATATGCTGCCACATCGCCACGAACAGTACTTTCAGATGCATTTCC
TCAATAGCGGACAGATTGAGCTACAGCTTGACGATCATCGCTACTCGGTGGAAGCGCCCCTGTTTGTCCTGACGCCGCCG
TCAGTACCTCATGCGTTTATTACGGAGTCTGACGCCGACGGTCATGTGTTGACGGTACGGGAAGATCTGATCTGGCCCCT
GCTGGAAGTTCTTTATCCAGGCACTCGGGAAACCTTCGGCCTGCCGGGGATTTGCCTGTCACTGGCAGATAAACCCGACG
AACTGGCGGCGCTGGAACACTATTGGCAACTGATAGAGCGGGAATCGGTAGAACAACTGCCTGGACGGGAACACACCCTG
ACGTTACTGGCACAGGCAGTGTTCACCCTACTGCTGCGTAACGCAAAACTCGACGACCATGCCGCCAGCGGAATGCGCGG
AGAATTAAAACTGTTCCAGCGTTTTCATATGCTGATTGAAAGCCATTTTCATCAGCACTGGACAGTACCGGATTACGCTA
ACGAACTGCATATCACCGAATCACGCCTCACGGACATCTGCCGCCGCTTTGCCAACCGTCCGCCAAAACGGTTGATTTTC
GACAGGCAGCTGCGAGAAGCCAAGCGGCTGCTGCTGTTTTCTGATAACGCCGTGAACAATATTGCCTGGCAACTCGGTTT
TAAGGATCCAGCTTATTTTGCGCGCTTTTTTAATCGCTTAGTCGGTTGCTCGCCCAGTGCTTATCGTGCCAAAAAAGTAC
CTGTGACGTGA

Upstream 100 bases:

>100_bases
ATTGTGGTTTGTTGCCGCGCTGCTGGTGATTGGTGCGGGGATTATCTGGGCAATTCCAATGCAGTCCTCCCGTCCGCGAG
CGACCCCGTAAGGAACGACG

Downstream 100 bases:

>100_bases
AAATCCCTTAGCCTTAACGGGAAACCAGGCACCACCTGCTATTCCCCTTTCTCCGCCTGGAGCAAGGGGATTTAGTAACG
TCAAAAATCGCTAAAAGCGA

Product: 4-hydroxyphenylacetate catabolism regulatory protein HpaA

Products: NA

Alternate protein names: Transcriptional Regulator AraC Family; Transcriptional Regulator; Helix-Turn-Helix Domain-Containing Protein; 4-Hydroxyphenylacetate Catabolism Regulatory Protein HpaA; Transcriptional Regulator PobR; Transcriptional Regulatory Protein; Regulator Of 4HPA-Hydroxylase Operon; AraC-Family Transcriptional Regulator; Helix-Turn-Helix- Domain Containing Protein AraC Type; PobR Regulator; AraC Family Transcription Regulator; Transcriptional Regulator AraC Family Protein; Transcriptional Regulator Arac Family; Transcriptional Regulator Pobr Arac Family Protein; AraC Protein; AraC Family Regulatory Protein; Transcriptional Regulatory Protein AraC-Type; Regulatory Protein; AraC/XylS Family Transcription Factor; AraC-Type Regulatory Protein; Helix-Turn-Helix AraC Type; Regulator Of 4hpa-Hydroxylase Operon; Transcriptional Regulator Protein; AraC Family Transcription Regulator Protein

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MCDRQIANIDISKEYDESLGTDDVHYQSFARMAAFFGRHMLPHRHEQYFQMHFLNSGQIELQLDDHRYSVEAPLFVLTPP
SVPHAFITESDADGHVLTVREDLIWPLLEVLYPGTRETFGLPGICLSLADKPDELAALEHYWQLIERESVEQLPGREHTL
TLLAQAVFTLLLRNAKLDDHAASGMRGELKLFQRFHMLIESHFHQHWTVPDYANELHITESRLTDICRRFANRPPKRLIF
DRQLREAKRLLLFSDNAVNNIAWQLGFKDPAYFARFFNRLVGCSPSAYRAKKVPVT

Sequences:

>Translated_296_residues
MCDRQIANIDISKEYDESLGTDDVHYQSFARMAAFFGRHMLPHRHEQYFQMHFLNSGQIELQLDDHRYSVEAPLFVLTPP
SVPHAFITESDADGHVLTVREDLIWPLLEVLYPGTRETFGLPGICLSLADKPDELAALEHYWQLIERESVEQLPGREHTL
TLLAQAVFTLLLRNAKLDDHAASGMRGELKLFQRFHMLIESHFHQHWTVPDYANELHITESRLTDICRRFANRPPKRLIF
DRQLREAKRLLLFSDNAVNNIAWQLGFKDPAYFARFFNRLVGCSPSAYRAKKVPVT
>Mature_296_residues
MCDRQIANIDISKEYDESLGTDDVHYQSFARMAAFFGRHMLPHRHEQYFQMHFLNSGQIELQLDDHRYSVEAPLFVLTPP
SVPHAFITESDADGHVLTVREDLIWPLLEVLYPGTRETFGLPGICLSLADKPDELAALEHYWQLIERESVEQLPGREHTL
TLLAQAVFTLLLRNAKLDDHAASGMRGELKLFQRFHMLIESHFHQHWTVPDYANELHITESRLTDICRRFANRPPKRLIF
DRQLREAKRLLLFSDNAVNNIAWQLGFKDPAYFARFFNRLVGCSPSAYRAKKVPVT

Specific function: Unknown

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 34354; Mature: 34354

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCDRQIANIDISKEYDESLGTDDVHYQSFARMAAFFGRHMLPHRHEQYFQMHFLNSGQIE
CCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEE
LQLDDHRYSVEAPLFVLTPPSVPHAFITESDADGHVLTVREDLIWPLLEVLYPGTRETFG
EEECCCEEEECCCEEEECCCCCCCCEEECCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCC
LPGICLSLADKPDELAALEHYWQLIERESVEQLPGREHTLTLLAQAVFTLLLRNAKLDDH
CCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHH
AASGMRGELKLFQRFHMLIESHFHQHWTVPDYANELHITESRLTDICRRFANRPPKRLIF
HHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHHHHCCCHHHHHH
DRQLREAKRLLLFSDNAVNNIAWQLGFKDPAYFARFFNRLVGCSPSAYRAKKVPVT
HHHHHHHHHEEEECCCCCCHHEEEECCCCHHHHHHHHHHHHCCCCCHHCCCCCCCC
>Mature Secondary Structure
MCDRQIANIDISKEYDESLGTDDVHYQSFARMAAFFGRHMLPHRHEQYFQMHFLNSGQIE
CCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEE
LQLDDHRYSVEAPLFVLTPPSVPHAFITESDADGHVLTVREDLIWPLLEVLYPGTRETFG
EEECCCEEEECCCEEEECCCCCCCCEEECCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCC
LPGICLSLADKPDELAALEHYWQLIERESVEQLPGREHTLTLLAQAVFTLLLRNAKLDDH
CCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHH
AASGMRGELKLFQRFHMLIESHFHQHWTVPDYANELHITESRLTDICRRFANRPPKRLIF
HHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHHHHCCCHHHHHH
DRQLREAKRLLLFSDNAVNNIAWQLGFKDPAYFARFFNRLVGCSPSAYRAKKVPVT
HHHHHHHHHEEEECCCCCCHHEEEECCCCHHHHHHHHHHHHCCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA