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The map label for this gene is ygjR

Identifier: 157162563

GI number: 157162563

Start: 3280647

End: 3281633

Strand: Direct

Name: ygjR

Synonym: EcHS_A3269

Alternate gene names: 157162563

Gene position: 3280647-3281633 (Clockwise)

Preceding gene: 157162562

Following gene: 157162564

Centisome position: 70.65

GC content: 52.58

Gene sequence:

>987_bases
ATGATACGTTTCGCTGTGATTGGTACGAACTGGATCACTCGCCAGTTCGTCGAGGCCGCCCATGAGAGCGGTAAATACAA
GTTAACCGCCGTATATTCCCGCAGCCTTGAACAGGCCCAGCACTTCGCCAATGATTTTTCTGTCGAGCATCTGTTTACCT
CGCTGGAAGCGATGGCGGAAAGCGATGCCATTGACGCGGTGTATATTGCCAGCCCGAATTCCCTGCATTTTTCCCAGACA
CAACTTTTCCTTAGCCATAAAATTAATGTGATTTGCGAGAAACCGCTGGCGTCGAATCTGGCGGAAGTGGATGCCGCCAT
TGCCTGTGCGCGGGAAAATCAGGTGGTGCTGTTTGAGGCATTTAAAACCGCCTGCCTGCCGAACTTTCATTTGTTGCGCC
AGGCGCTGCCGAAAGTCGGCAAACTGCGGAAAGTCTTTTTCAACTATTGCCAGTATTCCTCGCGGTATCAACGTTACCTG
GATGGTGAGAATCCCAACACCTTTAATCCGGCATTCTCTAACGGTTCAATTATGGATATCGGTTTTTACTGTCTGGCGTC
GGCGGTGGCGTTATTTGGTGAGCCGAAAAGCGTGCAGGCAACCGCCAGTTTGCTGGCAAGCGGCGTTGACGCCCAGGGCG
TGGTGGTGATGGATTACGGTGATTTCAGCGTCACCTTGCAGCACTCAAAAGTCAGTGATTCTGTCCTGGCGAGCGAGATT
CAGGGCGAAGCAGGATCGCTGGTGATTGAAAAACTGTCTGAATGCCAGAAAGTGTGCTTCGTGCCGCGTGGCAGCCAAAT
GCAGGATCTCACCCAGCCGCAGCATATTAATACCATGCTCTACGAAGCAGAGCTGTTCGCTACCCTGGTGGATGAGCATC
TGGTGGATCATCCAGGGCTGGCGGTCAGTCGCATCACCGCCAAACTGCTGACCGAGATCCGCCGCCAGACTGGGGTGATT
TTTCCGGCAGATAGCGTAAAACTATAA

Upstream 100 bases:

>100_bases
TGGCTGTCCGGCGCAGAAATAATGCGTATCTGCGCACGTCGAAGATGAAAAAGGCGTGCTACATTGACGACAGAATCCCT
TTATGGAGTATCCACGCGTT

Downstream 100 bases:

>100_bases
TTGCCAAAGTAAAACAGTGTAAAAGGTATGTAACAGACCATTGACTGGCTGAATGGTCTGTCATACTTTGTTACCTGCAA
AGGGGAGTAACTTCATTGCC

Product: oxidoreductase, NAD binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MIRFAVIGTNWITRQFVEAAHESGKYKLTAVYSRSLEQAQHFANDFSVEHLFTSLEAMAESDAIDAVYIASPNSLHFSQT
QLFLSHKINVICEKPLASNLAEVDAAIACARENQVVLFEAFKTACLPNFHLLRQALPKVGKLRKVFFNYCQYSSRYQRYL
DGENPNTFNPAFSNGSIMDIGFYCLASAVALFGEPKSVQATASLLASGVDAQGVVVMDYGDFSVTLQHSKVSDSVLASEI
QGEAGSLVIEKLSECQKVCFVPRGSQMQDLTQPQHINTMLYEAELFATLVDEHLVDHPGLAVSRITAKLLTEIRRQTGVI
FPADSVKL

Sequences:

>Translated_328_residues
MIRFAVIGTNWITRQFVEAAHESGKYKLTAVYSRSLEQAQHFANDFSVEHLFTSLEAMAESDAIDAVYIASPNSLHFSQT
QLFLSHKINVICEKPLASNLAEVDAAIACARENQVVLFEAFKTACLPNFHLLRQALPKVGKLRKVFFNYCQYSSRYQRYL
DGENPNTFNPAFSNGSIMDIGFYCLASAVALFGEPKSVQATASLLASGVDAQGVVVMDYGDFSVTLQHSKVSDSVLASEI
QGEAGSLVIEKLSECQKVCFVPRGSQMQDLTQPQHINTMLYEAELFATLVDEHLVDHPGLAVSRITAKLLTEIRRQTGVI
FPADSVKL
>Mature_328_residues
MIRFAVIGTNWITRQFVEAAHESGKYKLTAVYSRSLEQAQHFANDFSVEHLFTSLEAMAESDAIDAVYIASPNSLHFSQT
QLFLSHKINVICEKPLASNLAEVDAAIACARENQVVLFEAFKTACLPNFHLLRQALPKVGKLRKVFFNYCQYSSRYQRYL
DGENPNTFNPAFSNGSIMDIGFYCLASAVALFGEPKSVQATASLLASGVDAQGVVVMDYGDFSVTLQHSKVSDSVLASEI
QGEAGSLVIEKLSECQKVCFVPRGSQMQDLTQPQHINTMLYEAELFATLVDEHLVDHPGLAVSRITAKLLTEIRRQTGVI
FPADSVKL

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family

Homologues:

Organism=Homo sapiens, GI7657212, Length=348, Percent_Identity=25.5747126436782, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI145693182, Length=328, Percent_Identity=100, Blast_Score=680, Evalue=0.0,
Organism=Drosophila melanogaster, GI24581117, Length=345, Percent_Identity=25.7971014492754, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24581115, Length=339, Percent_Identity=23.8938053097345, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24584727, Length=261, Percent_Identity=25.6704980842912, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YGJR_ECOLI (P42599)

Other databases:

- EMBL:   U18997
- EMBL:   U18997
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   D65097
- RefSeq:   AP_003636.1
- RefSeq:   NP_417558.2
- ProteinModelPortal:   P42599
- SMR:   P42599
- STRING:   P42599
- EnsemblBacteria:   EBESCT00000000760
- EnsemblBacteria:   EBESCT00000015273
- GeneID:   947600
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW3058
- KEGG:   eco:b3087
- EchoBASE:   EB2588
- EcoGene:   EG12729
- eggNOG:   COG0673
- GeneTree:   EBGT00050000011165
- HOGENOM:   HBG407231
- OMA:   QTGVVFP
- ProtClustDB:   CLSK880576
- BioCyc:   EcoCyc:G7606-MONOMER
- Genevestigator:   P42599
- GO:   GO:0005488
- InterPro:   IPR016040
- InterPro:   IPR000683
- Gene3D:   G3DSA:3.40.50.720

Pfam domain/function: PF01408 GFO_IDH_MocA

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36215; Mature: 36215

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x176ac400)-;

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRFAVIGTNWITRQFVEAAHESGKYKLTAVYSRSLEQAQHFANDFSVEHLFTSLEAMAE
CEEEEEECCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHC
SDAIDAVYIASPNSLHFSQTQLFLSHKINVICEKPLASNLAEVDAAIACARENQVVLFEA
CCCCCEEEEECCCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCCCCEEEEEH
FKTACLPNFHLLRQALPKVGKLRKVFFNYCQYSSRYQRYLDGENPNTFNPAFSNGSIMDI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHH
GFYCLASAVALFGEPKSVQATASLLASGVDAQGVVVMDYGDFSVTLQHSKVSDSVLASEI
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEECCEEEEEECCCCHHHHHHHHH
QGEAGSLVIEKLSECQKVCFVPRGSQMQDLTQPQHINTMLYEAELFATLVDEHLVDHPGL
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
AVSRITAKLLTEIRRQTGVIFPADSVKL
HHHHHHHHHHHHHHHHCCEEECCCCCCH
>Mature Secondary Structure
MIRFAVIGTNWITRQFVEAAHESGKYKLTAVYSRSLEQAQHFANDFSVEHLFTSLEAMAE
CEEEEEECCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHC
SDAIDAVYIASPNSLHFSQTQLFLSHKINVICEKPLASNLAEVDAAIACARENQVVLFEA
CCCCCEEEEECCCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCCCCEEEEEH
FKTACLPNFHLLRQALPKVGKLRKVFFNYCQYSSRYQRYLDGENPNTFNPAFSNGSIMDI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHH
GFYCLASAVALFGEPKSVQATASLLASGVDAQGVVVMDYGDFSVTLQHSKVSDSVLASEI
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEECCEEEEEECCCCHHHHHHHHH
QGEAGSLVIEKLSECQKVCFVPRGSQMQDLTQPQHINTMLYEAELFATLVDEHLVDHPGL
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
AVSRITAKLLTEIRRQTGVIFPADSVKL
HHHHHHHHHHHHHHHHCCEEECCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503