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The map label for this gene is visC [H]

Identifier: 157162366

GI number: 157162366

Start: 3078626

End: 3079828

Strand: Reverse

Name: visC [H]

Synonym: EcHS_A3065

Alternate gene names: 157162366

Gene position: 3079828-3078626 (Counterclockwise)

Preceding gene: 157162367

Following gene: 157162365

Centisome position: 66.33

GC content: 54.7

Gene sequence:

>1203_bases
ATGCAAAGTGTTGATGTAGCCATTGTTGGTGGCGGCATGGTGGGGCTGGCGGTTGCCTGCGGCTTACAGGGGAGCGGCTT
ACGCGTTGCCGTACTGGAGCAGCGCGTACCGGAACCTCTGGCGGCGGATGCACCACCACAACTGCGCGTTTCGGCTATCA
ATGCCGCCAGCGAAAAATTACTCACCCGTCTTGGCGTCTGGCAGGACATTCTCTCTCGTAGGGCCAGTTGTTATCACGGT
ATGGAAGTGTGGGACAAAGACAGTTTTGGTCACATTTCGTTTGACGATCAAAGCATGGGCTATAGCCATCTTGGGCATAT
CGTTGAAAACTCAGTGATTCACTACGCGCTGTGGAACAAAGCGCAGCAGTCGTCAGATATCACTCTGTTGGCCCCCGCAG
AATTACAGCAGGTCGCCTGGGGAGAAAATGAAACTTTCCTGACGCTGAAAGATGGCAGCATGTTAACGGCGCGTCTGGTG
ATTGGCGCGGACGGTGCTAATTCCTGGTTGCGCAACAAAGCAGATATTCCGCTGACTTTCTGGGATTATCAGCATCACGC
GCTGGTAGCGACCATTCGCACGGAAGAACCGCATGATGCGGTGGCGCGGCAGGTTTTCCATGGCGAAGGCATTCTGGCCT
TTTTACCGCTTAGCGATCCGCATCTTTGCTCAATTGTCTGGTCACTGTCGCCAGAGGAAGCGCAGCGGATGCAGCAGGCA
AGTGAAGATGAATTTAATCGCGCGTTAAATATCGCTTTTGATAATCGCCTGGGCTTATGCAAGGTTGAGAGCGCGCGTCA
GGTGTTCCCACTGACGGGGCGTTATGCGCGCCAGTTTGCCGCGCACCGTCTGGTGCTGGTGGGCGACGCCGCGCATACCA
TTCACCCGCTGGCGGGGCAGGGAGTAAATCTCGGCTTTATGGATGCTGCAGAGCTGATTGCTGAACTGAAACGGTTGCAT
CGTCAGGGGAAAGACATCGGGCAGTACATTTACCTGCGCCGGTATGAGCGTAGCCGCAAGCACAGTGCGGCGCTGATGCT
GGCTGGTATGCAGGGATTCCGCGATCTGTTTTCCGGTACCAATCCGGCGAAAAAACTGCTGCGTGATATTGGTTTGAAAC
TGGCCGACACGCTTCTTGGCGTTAAACCACAACTTATCCGCCAGGCAATGGGATTAAACGATTTGCCTGAATGGCTGCGT
TAA

Upstream 100 bases:

>100_bases
GGACTGATGACGATGGAATTATTCACCCCGGCACGCGATGTGCTGGCGCAGCGCACCCTCGGTTGGGTGGCGCGTTGAAG
GCGGTTTTAAGGAATAAACA

Downstream 100 bases:

>100_bases
AAATTTCTCTTCTGCTGTTTATTTGATACCCATCACACTTTCATCTCCCGGTTTTTTCGCCGGGAGATTTTCCTCATTTG
AAATAAACTAATTTCACCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADAPPQLRVSAINAASEKLLTRLGVWQDILSRRASCYHG
MEVWDKDSFGHISFDDQSMGYSHLGHIVENSVIHYALWNKAQQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLV
IGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLSDPHLCSIVWSLSPEEAQRMQQA
SEDEFNRALNIAFDNRLGLCKVESARQVFPLTGRYARQFAAHRLVLVGDAAHTIHPLAGQGVNLGFMDAAELIAELKRLH
RQGKDIGQYIYLRRYERSRKHSAALMLAGMQGFRDLFSGTNPAKKLLRDIGLKLADTLLGVKPQLIRQAMGLNDLPEWLR

Sequences:

>Translated_400_residues
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADAPPQLRVSAINAASEKLLTRLGVWQDILSRRASCYHG
MEVWDKDSFGHISFDDQSMGYSHLGHIVENSVIHYALWNKAQQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLV
IGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLSDPHLCSIVWSLSPEEAQRMQQA
SEDEFNRALNIAFDNRLGLCKVESARQVFPLTGRYARQFAAHRLVLVGDAAHTIHPLAGQGVNLGFMDAAELIAELKRLH
RQGKDIGQYIYLRRYERSRKHSAALMLAGMQGFRDLFSGTNPAKKLLRDIGLKLADTLLGVKPQLIRQAMGLNDLPEWLR
>Mature_400_residues
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADAPPQLRVSAINAASEKLLTRLGVWQDILSRRASCYHG
MEVWDKDSFGHISFDDQSMGYSHLGHIVENSVIHYALWNKAQQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLV
IGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLSDPHLCSIVWSLSPEEAQRMQQA
SEDEFNRALNIAFDNRLGLCKVESARQVFPLTGRYARQFAAHRLVLVGDAAHTIHPLAGQGVNLGFMDAAELIAELKRLH
RQGKDIGQYIYLRRYERSRKHSAALMLAGMQGFRDLFSGTNPAKKLLRDIGLKLADTLLGVKPQLIRQAMGLNDLPEWLR

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=382, Percent_Identity=34.2931937172775, Blast_Score=178, Evalue=9e-45,
Organism=Homo sapiens, GI32967307, Length=347, Percent_Identity=34.0057636887608, Blast_Score=155, Evalue=5e-38,
Organism=Escherichia coli, GI1789273, Length=400, Percent_Identity=98.5, Blast_Score=808, Evalue=0.0,
Organism=Escherichia coli, GI1786883, Length=392, Percent_Identity=39.030612244898, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1789274, Length=393, Percent_Identity=30.7888040712468, Blast_Score=169, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI25146631, Length=431, Percent_Identity=32.0185614849188, Blast_Score=178, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6321694, Length=458, Percent_Identity=24.6724890829694, Blast_Score=110, Evalue=5e-25,
Organism=Drosophila melanogaster, GI19920760, Length=384, Percent_Identity=33.59375, Blast_Score=176, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 44234; Mature: 44234

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADAPPQLRVSAINAASEKL
CCCCEEEEECCCHHHHHHHHCCCCCCCEEEEEHHHCCCCCCCCCCCCEEEEHHHHHHHHH
LTRLGVWQDILSRRASCYHGMEVWDKDSFGHISFDDQSMGYSHLGHIVENSVIHYALWNK
HHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEECCCCCCCHHHHHHHHHCCEEEEEHHCC
AQQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLVIGADGANSWLRNKADIPLTF
CCCCCCEEEECHHHHHHHHCCCCCEEEEEECCCEEEEEEEEECCCCCHHHCCCCCCCEEE
WDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLSDPHLCSIVWSLSPEEAQRMQQA
ECCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHC
SEDEFNRALNIAFDNRLGLCKVESARQVFPLTGRYARQFAAHRLVLVGDAAHTIHPLAGQ
CHHHHHHEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHCEEEEEECCHHHHCCCCCC
GVNLGFMDAAELIAELKRLHRQGKDIGQYIYLRRYERSRKHSAALMLAGMQGFRDLFSGT
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPAKKLLRDIGLKLADTLLGVKPQLIRQAMGLNDLPEWLR
CHHHHHHHHHCHHHHHHHHCCCHHHHHHHCCCCCCHHHHC
>Mature Secondary Structure
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADAPPQLRVSAINAASEKL
CCCCEEEEECCCHHHHHHHHCCCCCCCEEEEEHHHCCCCCCCCCCCCEEEEHHHHHHHHH
LTRLGVWQDILSRRASCYHGMEVWDKDSFGHISFDDQSMGYSHLGHIVENSVIHYALWNK
HHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEECCCCCCCHHHHHHHHHCCEEEEEHHCC
AQQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLVIGADGANSWLRNKADIPLTF
CCCCCCEEEECHHHHHHHHCCCCCEEEEEECCCEEEEEEEEECCCCCHHHCCCCCCCEEE
WDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLSDPHLCSIVWSLSPEEAQRMQQA
ECCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHC
SEDEFNRALNIAFDNRLGLCKVESARQVFPLTGRYARQFAAHRLVLVGDAAHTIHPLAGQ
CHHHHHHEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHCEEEEEECCHHHHCCCCCC
GVNLGFMDAAELIAELKRLHRQGKDIGQYIYLRRYERSRKHSAALMLAGMQGFRDLFSGT
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPAKKLLRDIGLKLADTLLGVKPQLIRQAMGLNDLPEWLR
CHHHHHHHHHCHHHHHHHHCCCHHHHHHHCCCCCCHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]