Click here to switch to the map view.

The map label for this gene is ais [H]

Identifier: 157161738

GI number: 157161738

Start: 2405805

End: 2406407

Strand: Reverse

Name: ais [H]

Synonym: EcHS_A2397

Alternate gene names: 157161738

Gene position: 2406407-2405805 (Counterclockwise)

Preceding gene: 157161746

Following gene: 157161736

Centisome position: 51.82

GC content: 42.29

Gene sequence:

>603_bases
GTGTTAGCTTTTTGCCGCTCATCATTGAAGTCAAAAAAATATTTCATCATTTTACTGGCGCTCGCTGCAATTGCCGGACT
GGGTACTCATGCCGCCTGGAGTAGCAATGGTTTGCCACGTATCGACAATAAAACATTGGCCAGACTGGCACAGCAGCACC
CGGTTGTCGTTTTGTTTCGCCATGCTGAACGTTGCGATCGTTCAACCAATCAATGCTTGTCAGATATAACAGGTATTACG
GTTAAAGGTACCCAGGATGCCCGTGAACTGGGCAACGCTTTTAGTGCTGATATCCCTGATTTCGATCTTTATTCCAGTAA
TACCGTCCGGACCATTCAGTCGGCGACCTGGTTTTCAGCGGGTAAAAAGCTGACGGTAGATAAACGATTTCTTCAGTGCG
GTAATGATATTTATAGTGCAATTAAAGACTTACAAAGCAAAGCACCTGATAAAAATATCGTTATTTTTACCCATAATCAT
TGCCTGACATATATTGCTAAAGATAAGCGTGATGCGACATTTAAACCTGATTATCTGAATGGTTTAGTCATGCATGTGGA
AAAAGGCAAAGTTTATCTGGATGGGGAATTCGTTAACCACTAA

Upstream 100 bases:

>100_bases
GTAGGATTTTTAATATTACACCAACTGCTAATTATCGCCAGAAATGTCGCTCAATTTCACGGTAATTGTCTGGTTGCGCT
TGTCTATAGGTGGAGTTTAC

Downstream 100 bases:

>100_bases
ATTTTCAATCTGACAGCCAGTAATGGCTGTCATCATTGTTACAGAAGACCTTTCAAACGTAACGTTTTTCGGGTGGCAAC
GTTCAAATCATAGTGCACCA

Product: phosphoglycerate mutase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNKTLARLAQQHPVVVLFRHAERCDRSTNQCLSDITGIT
VKGTQDARELGNAFSADIPDFDLYSSNTVRTIQSATWFSAGKKLTVDKRFLQCGNDIYSAIKDLQSKAPDKNIVIFTHNH
CLTYIAKDKRDATFKPDYLNGLVMHVEKGKVYLDGEFVNH

Sequences:

>Translated_200_residues
MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNKTLARLAQQHPVVVLFRHAERCDRSTNQCLSDITGIT
VKGTQDARELGNAFSADIPDFDLYSSNTVRTIQSATWFSAGKKLTVDKRFLQCGNDIYSAIKDLQSKAPDKNIVIFTHNH
CLTYIAKDKRDATFKPDYLNGLVMHVEKGKVYLDGEFVNH
>Mature_200_residues
MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNKTLARLAQQHPVVVLFRHAERCDRSTNQCLSDITGIT
VKGTQDARELGNAFSADIPDFDLYSSNTVRTIQSATWFSAGKKLTVDKRFLQCGNDIYSAIKDLQSKAPDKNIVIFTHNH
CLTYIAKDKRDATFKPDYLNGLVMHVEKGKVYLDGEFVNH

Specific function: Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. Ais subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788586, Length=200, Percent_Identity=97.5, Blast_Score=378, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR011310 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: NA

Molecular weight: Translated: 22295; Mature: 22295

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNKTLARLAQQHPVVVLFR
CCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEE
HAERCDRSTNQCLSDITGITVKGTQDARELGNAFSADIPDFDLYSSNTVRTIQSATWFSA
CHHHHCCHHHHHHHHHCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHC
GKKLTVDKRFLQCGNDIYSAIKDLQSKAPDKNIVIFTHNHCLTYIAKDKRDATFKPDYLN
CCEEEHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCCCCCCCHHHC
GLVMHVEKGKVYLDGEFVNH
EEEEEEECCEEEEECEECCC
>Mature Secondary Structure
MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNKTLARLAQQHPVVVLFR
CCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEE
HAERCDRSTNQCLSDITGITVKGTQDARELGNAFSADIPDFDLYSSNTVRTIQSATWFSA
CHHHHCCHHHHHHHHHCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHC
GKKLTVDKRFLQCGNDIYSAIKDLQSKAPDKNIVIFTHNHCLTYIAKDKRDATFKPDYLN
CCEEEHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCCCCCCCHHHC
GLVMHVEKGKVYLDGEFVNH
EEEEEEECCEEEEECEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA