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The map label for this gene is ubiG [H]

Identifier: 157161715

GI number: 157161715

Start: 2380549

End: 2381271

Strand: Direct

Name: ubiG [H]

Synonym: EcHS_A2372

Alternate gene names: 157161715

Gene position: 2380549-2381271 (Clockwise)

Preceding gene: 157161708

Following gene: 157161717

Centisome position: 51.27

GC content: 54.5

Gene sequence:

>723_bases
ATGAATGCCGAAAAATCGCCGGTAAACCATAACGTAGACCACGAAGAGATCGCTAAATTTGAAGCCGTCGCCTCCCGCTG
GTGGGATCTTGAAGGTGAGTTCAAACCGCTGCACCGCATTAACCCGCTGCGTCTGGGCTATATTGCCGAGCGTGCTGGCG
GTTTATTTGGCAAAAAGGTGCTCGATGTCGGTTGTGGCGGCGGCATTCTGGCCGAGAGTATGGCGCGCGAAGGCGCGACG
GTGACCGGTCTGGATATGGGCTTTGAGCCATTGCAGGTGGCAAAGCTGCACGCACTGGAAAGCGGCATTCAAGTGGATTA
CGTGCAGGAAACCGTGGAAGAGCACGCGGCAAAACATGCCGGGCAGTATGATGTGGTGACCTGCATGGAGATGCTGGAGC
ACGTCCCCGATCCGCAGTCAGTGGTCAGAGCCTGTGCGCAACTGGTGAAACCGGGCGGCGATGTCTTTTTCTCGACGCTT
AACCGCAACGGCAAGTCATGGCTGATGGCGGTGGTTGGCGCGGAACATATTTTGCGCATGGTGCCCAAAGGCACGCATGA
TGTGAAGAAGTTTATTAAACCGGCAGAGCTGCTTGGCTGGGTAGATCAGACAAGCCTTAAAGAGCGACATATAACCGGGC
TACATTACAACCCGATCACTAATACTTTTAAACTCGGCCCCGGCGTGGATGTGAACTATATGCTGCACACGCAGAATAAG
TGA

Upstream 100 bases:

>100_bases
TATAACACAGCCGCGCAGTTTGAGGTAAACCTATACGCTTTATTCACATCCAATGCCTGATATACTCGTTTGTCTTGCCA
ATTACGGAGTAGAAGTGCCA

Downstream 100 bases:

>100_bases
GGTTGATGTTTGGCCGCGCCAATGCCTGATGCGACGCTTGCCGCGTCTTATCAGGCCTACAAATGCTCCCCGTAGGCCGG
ATAAGGCGTTTACGCCGCAT

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGAT
VTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTL
NRNGKSWLMAVVGAEHILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNTFKLGPGVDVNYMLHTQNK

Sequences:

>Translated_240_residues
MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGAT
VTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTL
NRNGKSWLMAVVGAEHILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNTFKLGPGVDVNYMLHTQNK
>Mature_240_residues
MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGAT
VTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTL
NRNGKSWLMAVVGAEHILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNTFKLGPGVDVNYMLHTQNK

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=239, Percent_Identity=33.4728033472803, Blast_Score=157, Evalue=5e-39,
Organism=Escherichia coli, GI1788564, Length=240, Percent_Identity=99.5833333333333, Blast_Score=497, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI115533050, Length=239, Percent_Identity=31.3807531380753, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6324476, Length=240, Percent_Identity=31.6666666666667, Blast_Score=129, Evalue=5e-31,
Organism=Drosophila melanogaster, GI281365311, Length=229, Percent_Identity=33.6244541484716, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24585589, Length=227, Percent_Identity=33.4801762114537, Blast_Score=134, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 26530; Mature: 26530

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKV
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHCCHHHHHH
LDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHA
HHCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
GQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEHILRM
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
VPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNTFKLGPGVDVNYMLHTQNK
CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEECCCCCEEECCCCCCEEEEEEECCC
>Mature Secondary Structure
MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKV
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHCCHHHHHH
LDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHA
HHCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
GQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEHILRM
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
VPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNTFKLGPGVDVNYMLHTQNK
CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEECCCCCEEECCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA