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The map label for this gene is baeR

Identifier: 157161570

GI number: 157161570

Start: 2208517

End: 2209239

Strand: Direct

Name: baeR

Synonym: EcHS_A2221

Alternate gene names: 157161570

Gene position: 2208517-2209239 (Clockwise)

Preceding gene: 157161569

Following gene: 157161571

Centisome position: 47.56

GC content: 54.08

Gene sequence:

>723_bases
ATGACCGAGTTACCAATCGACGAAAACACACCGCGTATTTTGATCGTGGAAGATGAACCGAAGCTGGGGCAGTTGCTCAT
TGATTATCTGCGTGCTGCGAGCTATGCGCCGACGCTTATCAGCCACGGCGATCAGGTACTGCCGTATGTGCGCCAGACAC
CACCGGATCTGATCCTGTTAGATCTGATGCTCCCTGGCACCGATGGCCTGACGCTGTGCCGGGAAATTCGTCGTTTTTCT
GACATTCCGATCGTGATGGTGACGGCAAAAATCGAAGAGATCGATCGCCTGCTGGGGCTGGAGATTGGCGCAGATGATTA
TATCTGTAAGCCGTACAGCCCACGGGAAGTGGTAGCGCGCGTCAAAACCATTTTGCGCCGTTGCAAACCGCAGCGCGAGT
TGCAGCAACAGGATGCTGAAAGCCCGTTGATTATCGACGAAGGTCGTTTTCAGGCTTCATGGCGCGGTAAAATGCTTGAC
CTGACGCCTGCGGAATTTCGTCTGCTGAAAACGCTCTCTCACGAACCAGGAAAAGTGTTCTCCCGCGAGCAATTGCTCAA
TCATCTTTATGACGACTACCGCGTAGTAACCGACCGCACCATCGACAGCCACATTAAAAACCTGCGCCGCAAGCTGGAAT
CTCTCGACGCCGAACAGTCATTTATCCGCGCCGTTTATGGCGTCGGTTACCGCTGGGAAGCCGACGCCTGCCGCATCGTT
TAG

Upstream 100 bases:

>100_bases
TTGAAGCACATAATGGTCGCATTATTGCTGCCCATTCGCCTTTTGGCGGGGTAAGCATTACAGTAGAGTTACCGCTGGAA
CGGGATTTACAGAGAGAAGT

Downstream 100 bases:

>100_bases
TTTTAGCGACATTATTTTGTTAGCCGGAGATGGCGTTCAGACCAGATCCGGCAACATTATCCCACGCATGGTCAGCAAAC
TGACATTATCTCTCCGCCCT

Product: DNA-binding transcriptional regulator BaeR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFS
DIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLD
LTPAEFRLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRIV

Sequences:

>Translated_240_residues
MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFS
DIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLD
LTPAEFRLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRIV
>Mature_239_residues
TELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFSD
IPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLDL
TPAEFRLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRIV

Specific function: Member of the two-component regulatory system BaeS/BaeR. Activates the mdtABCD operon

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1788394, Length=240, Percent_Identity=100, Blast_Score=486, Evalue=1e-139,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=42.2222222222222, Blast_Score=168, Evalue=2e-43,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=40.1785714285714, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=37.4468085106383, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=37.3333333333333, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=35.5855855855856, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=31.7596566523605, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=35.1931330472103, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=34.0807174887892, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=34.2222222222222, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=32.2727272727273, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=33.1877729257642, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=31.8385650224215, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=30.0448430493274, Blast_Score=94, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BAER_ECOL6 (P69229)

Other databases:

- EMBL:   AE014075
- RefSeq:   NP_754493.1
- ProteinModelPortal:   P69229
- SMR:   P69229
- EnsemblBacteria:   EBESCT00000044244
- GeneID:   1037915
- GenomeReviews:   AE014075_GR
- KEGG:   ecc:c2605
- GeneTree:   EBGT00050000008651
- HOGENOM:   HBG753323
- OMA:   RCKPQRD
- ProtClustDB:   PRK10710
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00448
- SMART:   SM00862

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C; SSF46894 Bipartite_resp_reg_C-effector; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 27656; Mature: 27525

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILL
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHCCCCCEEEE
DLMLPGTDGLTLCREIRRFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVAR
EEECCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCEECCCCCEECCCCHHHHHHH
VKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLDLTPAEFRLLKTLSHEPGKVF
HHHHHHHCCCHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCHHHHHHHHHHCCCCCHHH
SREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRIV
HHHHHHHHHHHHHEEHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEECCCCCCCC
>Mature Secondary Structure 
TELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILL
CCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHCCCCCEEEE
DLMLPGTDGLTLCREIRRFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVAR
EEECCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCEECCCCCEECCCCHHHHHHH
VKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLDLTPAEFRLLKTLSHEPGKVF
HHHHHHHCCCHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCHHHHHHHHHHCCCCCHHH
SREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRIV
HHHHHHHHHHHHHEEHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157